|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|4957969||1445227||2018||7 صفحه PDF||سفارش دهید||دانلود کنید|
- An open-source tool for creating perfusion maps is proposed.
- The tool is written and called completely within the R computing environment.
- Perfusion maps are validated through a digital phantom.
- The package is freely available on Github.
Background and objectiveComputed tomography perfusion (CTP) is a widely used imaging modality especially in neuroimaging. Despite this, CTP is often prohibitive due to the dearth of free/open-source software. This could have wide-ranging implications for instruction and research. We have implemented an online-available CTP tool built and run completely within the R computing environment.MethodsCalled from within R, the user can select one of four different methods to construct a cerebral blood flow (CBF) map: (1) max-slope (2) singular value decomposition (3) block circulant singular value decomposition or (4) oscillation minimization singular value decomposition. The four methods are compared against a digital CBF phantom.ResultsAll four methods generate a CBF map, with the oscillation minimization technique giving the most accurate map.ConclusionsWe have constructed an easily accessible teaching and research tool to create a CBF map and made it freely available. We hope this tool will help facilitate understanding of the methods involved in constructing perfusion maps and be a valuable resource to future researchers.
Journal: Computer Methods and Programs in Biomedicine - Volume 153, January 2018, Pages 11-17