کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5133503 1492066 2017 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The position of prenylation of isoflavonoids and stilbenoids from legumes (Fabaceae) modulates the antimicrobial activity against Gram positive pathogens
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
The position of prenylation of isoflavonoids and stilbenoids from legumes (Fabaceae) modulates the antimicrobial activity against Gram positive pathogens
چکیده انگلیسی


- Chemical characterization of main phytochemicals in extracts from seven legume species.
- Antibacterial activity of legume seedling extracts tested against Gram positive pathogens L. monocytogenes and MRSA.
- Prenylated phenolic compounds significantly correlated with the antibacterial activity.
- Position of prenyl group within the phenolic skeleton influences the antibacterial activity.
- Prenylated phenolic compounds can be used as multi-purpose bioactive ingredients.

The legume plant family (Fabaceae) is a potential source of antimicrobial phytochemicals. Molecular diversity in phytochemicals of legume extracts was enhanced by germination and fungal elicitation of seven legume species, as established by RP-UHPLC-UV-MS. The relationship between phytochemical composition, including different types of skeletons and substitutions, and antibacterial properties of extracts was investigated. Extracts rich in prenylated isoflavonoids and stilbenoids showed potent antibacterial activity against Listeria monocytogenes and methicillin-resistant Staphylococcus aureus at concentrations between 0.05 and 0.1% (w/v). Prenylated phenolic compounds were significantly (p < 0.01) correlated with the antibacterial properties of the extracts. Furthermore, the position of the prenyl group within the phenolic skeleton also influenced the antibacterial activity. Overall, prenylated phenolics from legume seedlings can serve multiple purposes, e.g. as phytoestrogens they can provide health benefits and as natural antimicrobials they offer preservation of foods.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Food Chemistry - Volume 226, 1 July 2017, Pages 193-201
نویسندگان
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