کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5139022 1494861 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Enantiomeric quantification of amines by 1H and 13C NMR: First report of S-citronellal as chiral derivatization agent (CDA)
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
پیش نمایش صفحه اول مقاله
Enantiomeric quantification of amines by 1H and 13C NMR: First report of S-citronellal as chiral derivatization agent (CDA)
چکیده انگلیسی
The possibility of determining enantiomeric excess (ee) in chiral compounds by nuclear magnetic resonance (NMR) was discovered half a century ago and remains an important strategy nowadays. One way to determine ee in chiral compounds is to obtain diastereoisomers by using chiral derivatization agents (CDAs). CDAs bearing an aldehyde function have helped to discriminate primary chiral amines through a reaction that promptly yields imines. To the best of our knowledge, acyclic terpenes displaying an aldehyde function like S-citronellal have not been used in this context yet. In this study, we obtained excellent accuracy when we quantified aliphatic and aromatic amines by 1H and 13C NMR using S-citronellal as CDA. This analytical method proved to be fast and useful to quantify primary chiral amines.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Microchemical Journal - Volume 133, July 2017, Pages 208-215
نویسندگان
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