Menthol differs from other terpenic essential oil constituents

► Menthol is compared to other terpenes like camphor, thujone, and eucalyptol. ► Chemistry, channel interactions, and primary metabolism are different. ► Menthol shows anticonvulsant properties in vitro and in animals. ► No seizures have been reported after menthol overdose in humans. ► Seizures have been reported after camphor, thujone, and eucalyptus oil.