کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
6016643 | 1580020 | 2014 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Hemiconvulsion-Hemiplegia-Epilepsy syndrome associated with inflammatory-degenerative hystopathological findings in child with congenital adrenal hyperplasia
ترجمه فارسی عنوان
سندرم همی پللوژی-همیپلژیک-صرع مرتبط با یافته های هیپوتوپاتولوژی التهابی-دژنراتیو در کودک مبتلا به هیپرپلازی مادرزادی آدرنال
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کلمات کلیدی
هماچونوولسیون هلیکوباکترپیلوری، صرع، هیپرپلازی مادرزادی آدرنال، التهاب
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب تکاملی
چکیده انگلیسی
Hemiconvulsion-Hemiplegia (HH) syndrome represents an uncommon consequence of prolonged unilateral clonic or hemiconvulsive status epilepticus in childhood, usually occurring during a febrile illness, followed by ipsilateral hemiplegia. The subsequent appearance of focal seizures configures the so called Hemiconvulsion-Hemiplegia-Epilepsy (HHE) syndrome. The pathogenesis of HH/HHE syndrome is still unclear. We describe the case of a 4 year-old girl with congenital adrenal hyperplasia (CAH) whom developed HH/HHE syndrome with drug resistant seizures at the age of 21 months and underwent left cerebral hemispherotomy at the age of 3 years and 6 months. Histopathological findings showed the presence of an underlying inflammatory-degenerative process. Disregulation of the inflammatory cascade has been proposed as one of the possible pathogenetic mechanisms underlying HH/HHE syndrome. To our knowledge however, this is the first report of an association with a histologically documented inflammatory process. The clinical and histopathological findings of our reported case lend support to the possible role of inflammation in the pathogenesis of HH/HHE syndrome.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: European Journal of Paediatric Neurology - Volume 18, Issue 3, May 2014, Pages 416-419
Journal: European Journal of Paediatric Neurology - Volume 18, Issue 3, May 2014, Pages 416-419
نویسندگان
Domenico Serino, Francesca Diomedi Camassei, Olivier Delalande, Carlo E. Marras, Nicola Specchio, Federico Vigevano, Lucia Fusco,