کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7211419 | 1469257 | 2018 | 20 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antileishmanial potential of medicinal plant extracts from the North-West of Morocco
ترجمه فارسی عنوان
پتانسیل ضد عفونی عصاره گیاهان دارویی از شمال غرب مراکش
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی (عمومی)
چکیده انگلیسی
The aim of this study is to evaluate the antileishmanial activity of selected medicinal plants from the North-West of Morocco. Plant extracts were prepared by maceration using methanol, ethanol, and n-hexane. The antileishmanial activity was evaluated against Leishmania major, Leishmania tropica, and Leishmania infantum using MTT (3-(4.5-dimethylthiazol-2yl)-2.5-diphenyltetrazolium bromide) assay. All plant extracts showed a reducing in cell promastigotes viability with variability depending on tested strains and type of extracts. The n-hexane extract showed the highest antileishmanial activity and L. infantum was the most sensitive parasite. The best growth inhibition was observed with Cistus crispus n-hexane extract against L. major (IC50 = 47.29 ± 2.25 μg/mL), Arbutus unedo n-hexane extract against L. infantum (IC50 = 64.05 ± 1.44 μg/mL) and Arbutus unedo n-hexane extract against L. tropica (IC50 = 79.57 ± 2.66 μg/mL). Considering these results, medicinal plants from the North-West of Morocco could constitute a promoter source for antileishmanial compounds.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Beni-Suef University Journal of Basic and Applied Sciences - Volume 7, Issue 1, March 2018, Pages 50-54
Journal: Beni-Suef University Journal of Basic and Applied Sciences - Volume 7, Issue 1, March 2018, Pages 50-54
نویسندگان
Abdelhakim Bouyahya, Abdeslam Et-Touys, Nadia Dakka, Hajiba Fellah, Jamal Abrini, Youssef Bakri,