کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
7211791 | 1469333 | 2018 | 27 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Novel 3D porous biocomposite scaffolds fabricated by fused deposition modeling and gas foaming combined technology
ترجمه فارسی عنوان
داربست های زیستی کامپوزیتی متخلخل 3 بعدی ساخته شده با مدل سازی رسوبدهی مخلوط شده و فن آوری ترکیب فوم گاز
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی (عمومی)
چکیده انگلیسی
Porosity of scaffolds plays an indispensable role in tissue regeneration. In this paper, hierarchical scaffolds with tailored macro/micro-porosity architectures for bone tissue engineering applications were introduced. Poly (vinyl alcohol) (PVA) has been innovatively blended into poly (lactic acid) (PLA) to fabricate composite filaments for fused deposition modeling (FDM). Customized macropores (pore sizeâ¯>â¯100â¯Î¼m) of scaffolds were designed and precisely fabricated by FDM process. Then the blended scaffolds were subjected to gas foaming process to create micropores (pore sizeâ¯<â¯10â¯Î¼m), which are hardly created by using 3DP techniques. Subsequently, PVA phase in the scaffolds was extracted by solvent etching method to create open pores, which are hard to create in gas foaming. The results showed that the scaffolds with 100-800â¯Î¼m macropores can be precisely fabricated by FDM technique. Meanwhile, 2-10â¯Î¼m micropores were successfully created. These novel scaffolds have the potential to be used in bone tissue regeneration.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Composites Part B: Engineering - Volume 152, 1 November 2018, Pages 151-159
Journal: Composites Part B: Engineering - Volume 152, 1 November 2018, Pages 151-159
نویسندگان
Ping Song, Changchun Zhou, Hongyuan Fan, Boqing Zhang, Xuan Pei, Yujiang Fan, Qing Jiang, Ruiying Bao, Qing Yang, Zhihong Dong, Xingdong Zhang,