MiR-21 regulates the ACAT1 gene in MCF-7 cells
Keywords: ACAT1; miR-21; PTEN; MCF-7; Cancer;
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Micro-RNA-181a suppresses progestin-promoted breast cancer cell growth
Keywords: BC; breast cancer; NET; norethisterone; PGRMC1; progesterone receptor membrane component 1; ER; estrogen receptor; miRNA; microRNA; UTR; untranslated region; BCL2; B-cell lymphoma 2; CASP-9; caspase 9; microRNA-181a; Breast cancer; MCF-7; Progestin; PGRMC
UHPLC-MSn-assisted characterization of bioactive alkaloids extracted from Nitraria sibirica leaves and enriched using response surface method and adsorption on macroporous resin
Keywords: DPPH; 2,2-diphenyl-1-picryl-hydrazyl; IC50; 50% inhibitory concentration; UHPLC-Q-Orbitrap-MS; ultra-high-pressure liquid chromatography-quadrupole-orbitrap-mass spectrometry; DMSO; dimethyl sulfoxide; MCF-7; human breast carcinoma cells; Hela; cervical c
Copper (II) oxide nanozyme based electrochemical cytosensor for high sensitive detection of circulating tumor cells in breast cancer
Keywords: Circulating tumor cells; Electrochemical cytosensor; MCF-7; Reduced graphene oxide/gold nanoparticles composites; CuO nanozyme;
Identification of N-Hydroxycinnamamide analogues and their bio-evaluation against breast cancer cell lines
Keywords: Breast cancer; MDA-MB-231; MCF-7; N-Hydroxycinnamamide; HEK-293;
N-acetylcysteine modified hyaluronic acid-paclitaxel conjugate for efficient oral chemotherapy through mucosal bioadhesion ability
Keywords: HA; hyaluronic acid; PTX; paclitaxel; NAC; N-acetylcysteine; DCC; dicyclohexylcarbodiimide; DMAP; 4-dimethylaminopyridine; DMF; N,N-dimethylformamide; NAC-HA-PTX; NAC modified HA-PTX; CMC; critical micelle concentration; C6; coumarin 6; DS; the degree of
Design, synthesis and evaluate of novel dual FGFR1 and HDAC inhibitors bearing an indazole scaffold
Keywords: 1H-Indazol-3-amine and benzohydroxamic acids hybrids; HDACs; FGFR1; Dual inhibitor; MCF-7;
Cytotoxic effects of platinum nanoparticles obtained from pomegranate extract by the green synthesis method on the MCF-7 cell line
Keywords: Biosynthesis; Platinum nanoparticles; MCF-7; Toxicity; Monodisperse; Ultrasonication;
Impairment of the Gnα11-controlled expression of claudin-1 and MMP-9 and collective migration of human breast cancer MCF-7 cells by DHEAS
Keywords: Claudin-1; DHEAS; Cell migration; Gnα11; MCF-7; MMP-9;
Design and synthesis of novel imidazo[4,5-b]pyridine based compounds as potent anticancer agents with CDK9 inhibitory activity
Keywords: Imidazo[4,5-b]pyridines; Anticancer; CDK9; HCT116; MCF-7;
Low-dose doxorubicin with carotenoids selectively alters redox status and upregulates oxidative stress-mediated apoptosis in breast cancer cells
Keywords: Carotenoids; Doxorubicin; Breast cancer cells; Cytotoxicity; Oxidative stress-mediated apoptosis; AST; Astaxanthin; Bcl-2; B-cell lymphoma 2; Bax; Bcl-2 associated X protein; BC; β-Carotene; BCA; Bicinchoninic acid; BHT; Butylatedhydroxytoluene; DCF-DA;
Bioassay guided fractionation and cytotoxic activity of Daucus carota var. boissieri
Keywords: Apiaceae; Red carrot; Hexane; Cytotoxicity; MCF-7;
Design, synthesis and molecular modeling of new 4-phenylcoumarin derivatives as tubulin polymerization inhibitors targeting MCF-7 breast cancer cells
Keywords: 4-Phenylcoumarins; Thiazole; MCF-7; Tubulin polymerization; Apoptosis; Molecular modeling;
Biological applications of Ru(II) polypyridyl complexes
Keywords: FDA; United States Food and Drug Administration; PDT; photodynamic therapy; PS; photosensitizer; ROS; reactive oxygen species; PACT; photodynamic antimicrobial chemotherapy; NKP-1339; sodium salt of indazolium trans-[tetrachlorobis(1H-indazole)ruthenate(I
Preparation, evaluation and pharmacokinetic studies of spray dried PLGA polymeric submicron particles of simvastatin for the effective treatment of breast cancer
Keywords: Simvastatin; Nanospray dryer; MTT assay; MCF-7; Solid tumor;
Chrysophanol selectively represses breast cancer cell growth by inducing reactive oxygen species production and endoplasmic reticulum stress via AKT and mitogen-activated protein kinase signal pathways
Keywords: BT-474; MCF-7; Chrysophanol; Mitochondria-dependent apoptosis; ER stress;
Anti-cancer activity of di- and tri-organotin(IV) compounds with D-(+)-Galacturonic acid on human tumor cells
Keywords: Organotin(IV); D-(+)-Galacturonic acid; NMR; Anti cancer; HCT-116; MCF-7;
Synthesis of breast cancer targeting conjugate of temporin-SHa analog and its effect on pro- and anti-apoptotic protein expression in MCF-7 cells
Keywords: AMP; Antimicrobial peptides; ANOVA; Analysis of Variance; Bcl-2; B-cell lymphoma 2 (Bcl-2), Bax, BCL2 Associated X; DMSO; Dimethyl sulfoxide; TFA; Trifluoroacetic acid; FACS; Fluorescence-activated cell sorting; GAPDH; Glyceraldehyde 3-phosphate dehydroge
Structural properties for selective and efficient l-type amino acid transporter 1 (LAT1) mediated cellular uptake
Keywords: ARPE-19; a human retinal pigment epithelial cell line; ATCC; American Type Culture Collection; ASCT2; alanine-serine-cysteine transporter 2; BBB; Blood Brain Barrier; BCH; 2-aminobicyclo-(2,2,1)-heptane-2-carboxylic acid; CNS; Central Nervous System; CYP3
A new calcium 2,5-dihydroxybenzoate: Synthesis, characterization and antioxidant studies and stress mediated cytotoxity in MCF-7 cells
Keywords: 2,5-Dihydroxybenzoic acid; Gentisic acid; 2,5-Dihydroxybenzoate; Calcium; Pro-/antioxidant; MCF-7;
Redox-stimuli-responsive drug delivery systems with supramolecular ferrocenyl-containing polymers for controlled release
Keywords: A549; A549 lung cancer cells; AAO; anodized alumina substrates; Ad; adamantane; ALMA; allyl methacrylate; ATRP; atom transfer radical polymerization; AuNPs; gold nanoparticles; CAC; critical aggregation concentration; CB[7]; cucurbituril; β-CD; β-cyclod
Comprehensive review on flavonoids biological activities of Erythrina plant species
Keywords: 5-LOX; 5-lipoxygenase; AMPK; adenosine monophosphate-activated protein kinase; Bax; Bcl-2-associated X protein; BC; lymphoma cell line; Bcl-2; B-cell CLL/lymphoma 2; Caco2; human epithelial colorectal adenocarcinoma cells; CCRF-CEM; T lymphoblastoid cell
Signaling pathways activated by PACAP in MCF-7 breast cancer cells
Keywords: PACAP; MCF-7; p38; ERK1/2; AKT; ROS; Cancer; Signal transduction;
A review on the ethnomedicinal uses, phytochemistry and pharmacology of Alpinia officinarum Hance
Keywords: ABS; Akaferd blood stopper; AN; Aspergillus niger; AO; Alpinia officinarum; BC; Bacillus cereus; B16-F10; Mouse melanoma cell line; CA; Candida albicans; CAR; Constitutive androstane receptor; CH2CL2; Dichloromethane; DPPH; Diphenylpicrylhydrazyl; EA; Eth
The chemistry and pharmacology of Ligularia przewalskii: A review
Keywords: A375; human melanoma cells; ABTS; 2,2'-azinobis (3-ethylbenzothiazoline-6- sulfonic acid); AChE; acetylcholinesterase; AD; Alzheimer's disease; AGEs; advanced glycation endproducts; B16F10; mouse skin melanoma; BACE1; β-site amyloid precursor cleavin
New cytotoxic compounds from Myristica fatua Houtt leaves against MCF-7 cell lines
Keywords: Myristica fatua Houtt; (7S, 8R, 8â²S, 7â²S) 7,7â²-bis(3-hydroxy-5-methoxyphenyl)-8,8â²-dimethylbuthane-7,7â²-diol; 3”-Hydroxydemethyldactyloidin; Cytotoxic activity; MCF-7;
Triterpenoid of avocado (Persea americana) seed and its cytotoxic activity toward breast MCF-7 and liver HepG2 cancer cells
Keywords: Persea americana; Triterpenoid; MCF-7; HepG2; Cancer cells;
Research PaperInvestigation of the effect of pomegranate extract and monodisperse silver nanoparticle combination on MCF-7 cell line
Keywords: Cytotoxicity; Green synthesis; MCF-7; Nanomaterials; Silver nanoparticles;
Antitumor activity of resveratrol is independent of Cu(II) complex formation in MCF-7 cell line
Keywords: Copper; Resveratrol; MCF-7; ROS; Apoptosis;
Study on apoptosis effect of human breast cancer cell MCF-7 induced by lycorine hydrochloride via death receptor pathway
Keywords: Lycorine hydrochloride; MCF-7; Death receptor pathway; Apoptosis;
Phytochemical and cytotoxic investigations of pinguisanoids from liverwort Porella cordaeana
Keywords: Pinguisane; Porella cordaeana; MCF-7; HT-29; Liverwort; Sesquiterpene;
Synthesis and cytotoxic effects of (E)-3-(2,3-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one in MDA-MB231 and MCF-7 breast cancer cell lines
Keywords: ANOVA; one-way analysis of variance; DMMF; (E)-3-(2,3-dimethoxyphenyl)-1-(5-methylfuran-2-yl) prop-2-en-1-one; FTIR; Fourier transform infrared spectroscopy; IARC; International Agency for Research; IC50; half-maximal inhibition concentration; IFN-γ; Int
The role of ROS and NF-κB pathway in olmesartan induced-toxicity in HeLa and mcf-7 cell lines
Keywords: HeLa; MCF-7; Olmesartan; ROS; Rutin; Antioxidant; Apoptosis;
Photoactivated hypericin increases the expression of SOD-2 and makes MCF-7 cells resistant to photodynamic therapy
Keywords: Photodynamic therapy; Hypericin; SOD-2; MCF-7; Resistance;
Cytotoxic effects of Fritillaria imperialis L. extracts on human liver cancer cells, breast cancer cells and fibroblast-like cells
Keywords: Fritillaria imperialis L.; Liver cancer cells; MCF-7; Cytotoxicity; Apoptosis;
The T47D cell line is an ideal experimental model to elucidate the progesterone-specific effects of a luminal A subtype of breast cancer
Keywords: T47D; MCF-7; Estrogen receptor; Progesterone receptor; ERα; PR;
Curcumin synergizes with the endocannabinoid reuptake inhibitor OMDM-2 in human MCF-7 breast cancer and U-87 glioblastoma cells
Keywords: Î9-THC; Delta-9-tetrahydrocannabinol; 2-AG; 2-arachidonoylglycerol; AEA; Anandamide; BCL2; B-cell CLL/lymphoma 2; CB-1; Cannabinoid receptor 1; CB-2; Cannabinoid receptor 2; CI; Combination Index; CXCR4; chemokine receptor type 4; DDS; Drug delivery syst
Preparation and nanoformulation of new quinolone scaffold-based anticancer agents: Enhancing solubility for better cellular delivery
Keywords: Quinolines; Antiproliferative agents; Cytotoxicity; MCF-7; MDA-MB231; Poloxamers;
Epoxy clerodane diterpene inhibits MCF-7 human breast cancer cell growth by regulating the expression of the functional apoptotic genes Cdkn2A, Rb1, mdm2 and p53
Keywords: Epoxy clerodane diterpene; Tinospora cordifolia; Caspase; Apoptosis; MCF-7;
Cytotoxicity of trans-chalcone and licochalcone A against breast cancer cells is due to apoptosis induction and cell cycle arrest
Keywords: Apoptosis; CIDEA; Comet assay; Licochalcone A; MCF-7; Trans-chalcone; PCR Array;
Fulvestrant-loaded polymer-based nanoparticles for local drug delivery: Preparation and in vitro characterization
Keywords: Fulvestrant; Breast cancer; Polymer-based nanoparticles; PEG-b-PLGA; PEG-b-PCL; MCF-7;
Fluorescence and circular dichroism studies on the accessibility of tryptophan residues and unfolding of a jacalin-related α-d-galactose-specific lectin from mulberry (Morus indica)
Keywords: CD; circular dichroism; DSC; differential scanning calorimetry; Gdn.HCl; guanidine hydrochloride; Gdn.SCN; guanidinium thiocyanate; JRL; jacalin-related lectins; MLGL; mulberry latex galactose-specific lectin; MDCK cells; Madine-Darby canine kidney cells;
Phenolics from Rubus fairholmianus induces cytotoxicity and apoptosis in human breast adenocarcinoma cells
Keywords: Rubus; Apoptosis; Antioxidant; MCF-7; Breast cancer; Cytochrome c; Rubus fairholmianus root methanolic column subfraction; RFM; (2, 2-diphenyl-1-picrylhydrazyl); DPPH; (2, 2â²-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid)); ABTS; Trolox Equivalent An
Characterizing the biological and biochemical profile of six different scorpion venoms from the Buthidae and Scorpionidae family
Keywords: Grosphus; Babycurus; Hottentotta; Tityus; Metalloproteinases; Phospholipases; Antitumor; MCF-7; Post-translational modifications;
Gold nanostar-polymer hybrids for siRNA delivery: Polymer design towards colloidal stability and in vitro studies on breast cancer cells
Keywords: PHEA; PEG; Lipoic acid; Gold nanostars; siRNA delivery; MCF-7;
The effect of tomatine on metastasis related matrix metalloproteinase (MMP) activities in breast cancer cell model
Keywords: MMP; Matrix metalloproteinase; ECM; Extracellular matrix; MCF-7; Human breast cancer cell line; WI-38; Pulmonary fibroblast cell line; Breast cancer; Matrix metalloproteinase; Tomatine;
Facile synthesis of 2-D Cu doped WO3 nanoplates with structural, optical and differential anti cancer characteristics
Keywords: Doping; 2-D, Raman; Differential; MCF-7; Hep-2;
A Review on Phytoconstituents and Biological activities of Cuscuta species
Keywords: MDA-MB-231; human caucasian breast adenocarcinoma; MCF-7; breast adenocarcinoma from human; Hep 3B; human hepatocellular carcinoma cell lines; HEK 293; human embryonic kidney cell lines; RAW 264.7; breast adenocarcinoma from human; DPPH; intercellular adh
Chrysin loaded nanostructured lipid carriers (NLCs) triggers apoptosis in MCF-7 cancer cells by inhibiting the Nrf2 pathway
Keywords: Chrysin (PubChem CID: 5281607); Doxorubicin (PubChem CID: 31703); Glyceryl Behenate (PubChem CID: 5362585); Dimethyl Sulfoxide (PubChem CID: 679); MTT formazan (PubChem CID: 16218671); Miglyol (PubChem CID: 53471835); RPMI; Roswell Park Memorial Institute
Natural lipids enriched self-nano-emulsifying systems for effective co-delivery of tamoxifen and naringenin: Systematic approach for improved breast cancer therapeutics
Keywords: SNEDDS; Self-nano-emulsifying drug delivery systems; Smix; Surfactant mix; TMX; Tamoxifen; NG; Neringenin; PUFA; Polyunsaturated fatty acids; GIT; Gastrointestinal tract; Opt; Optimized; QbD; Quality by design; DoE; Design of experiment; CQA; Critical qua