In search of uracil derivatives as bioactive agents. Uracils and fused uracils: Synthesis, biological activity and applications Fulltext Access 30 Pages 2015
Kinetic and thermodynamic studies on the disulfide-bond reducing potential of hydrogen sulfide Fulltext Access 31 Pages 2015
A review of bioactive plant polysaccharides: Biological activities, functionalization, and biomedical applications Fulltext Access 31 Pages 2015
Magnesium sulfate affords protection against oxidative damage during severe preeclampsia Fulltext Access 31 Pages 2015
Cyclic nitroxide radicals attenuate inflammation and Hyper-responsiveness in a mouse model of allergic asthma Fulltext Access 32 Pages 2015
Oxidative stress in paroxysmal nocturnal hemoglobinuria and other conditions of complement-mediated hemolysis Fulltext Access 33 Pages 2015
Combating highly resistant emerging pathogen Mycobacterium abscessus and Mycobacterium tuberculosis with novel salicylanilide esters and carbamates Fulltext Access 33 Pages 2015
The role of matrix metalloproteinases in aging: Tissue remodeling and beyond Fulltext Access 33 Pages 2015
Plasmodium falciparum antioxidant protein reveals a novel mechanism for balancing turnover and inactivation of peroxiredoxins Fulltext Access 34 Pages 2015
Search for factors affecting antibacterial activity and toxicity of 1,2,4-triazole-ciprofloxacin hybrids Fulltext Access 35 Pages 2015
Nitric oxide diffusion to red blood cells limits extracellular, but not intraphagosomal, peroxynitrite formation by macrophages Fulltext Access 35 Pages 2015
Synthesis, carbonic anhydrase inhibition and cytotoxic activity of novel chromone-based sulfonamide derivatives Fulltext Access 36 Pages 2015
Synthesis and biological evaluation of 4-oxycoumarin derivatives as a new class of antifilarial agents Fulltext Access 36 Pages 2015
Incorporation of a Michael acceptor enhances the antitumor activity of triterpenoic acids Fulltext Access 36 Pages 2015
New coumarin-based fluorescent melatonin ligands. Design, synthesis and pharmacological characterization Fulltext Access 36 Pages 2015
Role of extracellular Hydrogen peroxide in regulation of iron homeostasis genes in neuronal cells: Implication in iron accumulation Fulltext Access 37 Pages 2015
Hemoglobin-induced lung vascular oxidation, inflammation, and remodeling contribute to the progression of hypoxic pulmonary hypertension and is attenuated in rats with repeated-dose haptoglobin administration Fulltext Access 37 Pages 2015
Discovery of a new class of antiviral compounds: Camphor imine derivatives Fulltext Access 37 Pages 2015
Lipocalin 2 promotes the migration and invasion of esophageal squamous cell carcinoma cells through a novel positive feedback loop Fulltext Access 37 Pages 2015
Synthesis, leishmanicidal, trypanocidal and cytotoxic activity of quinoline-hydrazone hybrids Fulltext Access 38 Pages 2015
Zinc and calcium modulate mitochondrial redox state and morphofunctional integrity Fulltext Access 38 Pages 2015
Computational and statistical methods for high-throughput analysis of post-translational modifications of proteins Fulltext Access 38 Pages 2015
Matrigel basement membrane matrix induces eccrine sweat gland cells to reconstitute sweat gland-like structures in nude mice Fulltext Access 38 Pages 2015
New and efficient approach for synthesis of novel bioactive [1,3,4]thiadiazoles incorporated with 1,3-thiazole moiety Fulltext Access 39 Pages 2015
Eculizumab treatment during pregnancy does not affect the complement system activity of the newborn Fulltext Access 40 Pages 2015
Design and studies of multiple mechanism of anti-Candida activity of a new potent Trp-rich peptide dendrimers Fulltext Access 40 Pages 2015
Determination of the topology of endoplasmic reticulum membrane proteins using redox-sensitive green-fluorescence protein fusions Fulltext Access 40 Pages 2015
Reactivity of selenium-containing compounds with myeloperoxidase-derived chlorinating oxidants: Second-order rate constants and implications for biological damage Fulltext Access 41 Pages 2015
Bond-based bilinear indices for computational discovery of novel trypanosomicidal drug-like compounds through virtual screening Fulltext Access 41 Pages 2015
Synthesis and biological evaluation of novel 2-heteroarylimino-1,3-thiazolidin-4-ones as potential anti-tumor agents Fulltext Access 41 Pages 2015
A click chemistry approach for the synthesis of mono and bis aryloxy linked coumarinyl triazoles as anti-tubercular agents Fulltext Access 41 Pages 2015
Fructose consumption reduces hippocampal synaptic plasticity underlying cognitive performance Fulltext Access 41 Pages 2015
An integrated transcriptomic and proteomic analysis of sea star epidermal secretions identifies proteins involved in defense and adhesion Fulltext Access 42 Pages 2015
Critical role of peroxiredoxin 6 in the repair of peroxidized cell membranes following oxidative stress Fulltext Access 42 Pages 2015
Generation and esterification of electrophilic fatty acid nitroalkenes in triacylglycerides Fulltext Access 42 Pages 2015
Regulatory cells induced by acute toxoplasmosis prevent the development of allergic lung inflammation Fulltext Access 42 Pages 2015
Design, synthesis, and anticancer evaluation of long-chain alkoxylated mono-carbonyl analogues of curcumin Fulltext Access 42 Pages 2015
Leishmanicidal, antiproteolytic, and mutagenic evaluation of alkyltriazoles and alkylphosphocholines Fulltext Access 42 Pages 2015
Synthesis and biological evaluation of boswellic acid-NSAID hybrid molecules as anti-inflammatory and anti-arthritic agents Fulltext Access 43 Pages 2015
The autophagic- lysosomal pathway determines the fate of glial cells under manganese- induced oxidative stress conditions Fulltext Access 43 Pages 2015
Piperazine scaffold: A remarkable tool in generation of diverse pharmacological agents Fulltext Access 43 Pages 2015
Myeloperoxidase impairs the contractile function in isolated human cardiomyocytes Fulltext Access 43 Pages 2015
A proteomic perspective of the interplay of Staphylococcus aureus and human alveolar epithelial cells during infection Fulltext Access 43 Pages 2015
Helicobacter pylori chronic infection and mucosal inflammation switches the human gastric glycosylation pathways Fulltext Access 44 Pages 2015
Nanoparticles can cross mouse placenta and induce trophoblast apoptosis Fulltext Access 44 Pages 2015
Formation of reactive oxygen species by human and bacterial pyruvate and 2-oxoglutarate dehydrogenase multienzyme complexes reconstituted from recombinant components Fulltext Access 44 Pages 2015
Insights into the importance for designing curcumin-inspired anticancer agents by a prooxidant strategy: The case of diarylpentanoids Fulltext Access 44 Pages 2015
Synthetic approaches, functionalization and therapeutic potential of quinazoline and quinazolinone skeletons: The advances continue Fulltext Access 46 Pages 2015
Metabolism alteration in follicular niche: The nexus among intermediary metabolism, mitochondrial function, and classic polycystic ovary syndrome Fulltext Access 46 Pages 2015
Synthesis and biological evaluation of novel aromatic-heterocyclic biphenyls as potent anti-leukemia agents Fulltext Access 46 Pages 2015
Comparative physiology and proteomic analysis of two wheat genotypes contrasting in drought tolerance Fulltext Access 47 Pages 2015
Perfluorooctanoic acid exposure induces endoplasmic reticulum stress in the liver and its effects are ameliorated by 4-phenylbutyrate Fulltext Access 47 Pages 2015
Design, synthesis and biological evaluation of novel pyrazoline-containing derivatives as potential tubulin assembling inhibitors Fulltext Access 47 Pages 2015
Design and synthesis of some new pyrazolyl-pyrazolines as potential anti-inflammatory, analgesic and antibacterial agents Fulltext Access 48 Pages 2015
Synthesis and biological evaluation of betulonic acid derivatives as antitumor agents Fulltext Access 49 Pages 2015
How synthetic membrane systems contribute to the understanding of lipid-driven endocytosis Fulltext Access 50 Pages 2015
Discovery and characterization of aryl isonitriles as a new class of compounds versus methicillin- and vancomycin-resistant Staphylococcus aureus Fulltext Access 50 Pages 2015
Identification of phenolics in litchi and evaluation of anticancer cell proliferation activity and intracellular antioxidant activity Fulltext Access 50 Pages 2015
Clusterin gene is predominantly regulated by histone modifications in human colon cancer and ectopic expression of the nuclear isoform induces cell death Fulltext Access 51 Pages 2015
Amelioration of radiation-induced hematopoietic syndrome by an antioxidant chlorophyllin through increased stem cell activity and modulation of hematopoiesis Fulltext Access 51 Pages 2015
Caffeic acid attenuates rat liver reperfusion injury through sirtuin 3-dependent regulation of mitochondrial respiratory chain Fulltext Access 51 Pages 2015
New multifunctional melatonin-derived benzylpyridinium bromides with potent cholinergic, antioxidant, and neuroprotective properties as innovative drugs for Alzheimer's disease Fulltext Access 53 Pages 2015
Design of a serotonin 4 receptor radiotracer with decreased lipophilicity for single photon emission computed tomography Fulltext Access 53 Pages 2015
Discovery and preliminary evaluation of 2-aminobenzamide and hydroxamate derivatives containing 1,2,4-oxadiazole moiety as potent histone deacetylase inhibitors Fulltext Access 54 Pages 2015
Plasma membrane and cytoskeleton dynamics during single-cell wound healing Fulltext Access 54 Pages 2015
Oxidative stress, mitochondrial and proteostasis malfunction in adrenoleukodystrophy: A paradigm for axonal degeneration Fulltext Access 55 Pages 2015
Alternative functions of the brain transsulfuration pathway represent an underappreciated aspect of brain redox biochemistry with significant potential for therapeutic engagement Fulltext Access 55 Pages 2015
Bioactive benzofuran derivatives: An insight on lead developments, radioligands and advances of the last decade Fulltext Access 56 Pages 2015
Hybrid compounds with two redox centres: Modular synthesis of chalcogen-containing lapachones and studies on their antitumor activity Fulltext Access 57 Pages 2015
Peroxynitrous acid induces structural and functional modifications to basement membranes and its key component, laminin Fulltext Access 58 Pages 2015
Design, synthesis, and biological evaluation of benzoselenazole-stilbene hybrids as multi-target-directed anti-cancer agents Fulltext Access 61 Pages 2015
Benzenediol lactones: a class of fungal metabolites with diverse structural features and biological activities Fulltext Access 65 Pages 2015
Characterization of proteins in soybean roots under flooding and drought stresses Fulltext Access 66 Pages 2015
Design, synthesis, biological evaluation and molecular docking studies of phenylpropanoid derivatives as potent anti-hepatitis B virus agents Fulltext Access 67 Pages 2015
Synthesis and structure-activity relationship of novel 1,4-diazabicyclo[2.2.2]octane derivatives as potent antimicrobial agents Fulltext Access 68 Pages 2015
Hyaluronan fragments as mediators of inflammation in allergic pulmonary disease Fulltext Access 68 Pages 2015
Synthesis and structure-activity relationship study of benzofuran-based chalconoids bearing benzylpyridinium moiety as potent acetylcholinesterase inhibitors Fulltext Access 70 Pages 2015
Discovery and optimization of adamantane carboxylic acid derivatives as potent diacylglycerol acyltransferase 1 inhibitors for the potential treatment of obesity and diabetes Fulltext Access 73 Pages 2015
Proteomic analysis of flooded soybean root exposed to aluminum oxide nanoparticles Fulltext Access 73 Pages 2015
Novel 2H-chromen-2-one derivatives of resveratrol: Design, synthesis, modeling and use as human monoamine oxidase inhibitors Fulltext Access 76 Pages 2015