Transcriptionally Driven DNA Replication Program of the Human Parasite Leishmania major Fulltext Access 13 Pages 2016
Tissue-Resident CD169+ Macrophages Form a Crucial Front Line against Plasmodium Infection Fulltext Access 13 Pages 2016
Selective Maturation of Temporal Dynamics of Intracortical Excitatory Transmission at the Critical Period Onset Fulltext Access 13 Pages 2016
Nucleolin-Mediated RNA Localization Regulates Neuron Growth and Cycling Cell Size Fulltext Access 13 Pages 2016
The ID1-CULLIN3 Axis Regulates Intracellular SHH and WNT Signaling in Glioblastoma Stem Cells Fulltext Access 13 Pages 2016
MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload Fulltext Access 13 Pages 2016
Functional Genomic Screening Reveals Splicing of the EWS-FLI1 Fusion Transcript as a Vulnerability in Ewing Sarcoma Fulltext Access 13 Pages 2016
The Rag-Ragulator Complex Regulates Lysosome Function and Phagocytic Flux in Microglia Fulltext Access 13 Pages 2016
The Tubulation Activity of a Fission Yeast F-BAR Protein Is Dispensable for Its Function in Cytokinesis Fulltext Access 13 Pages 2016
Tet3 Reads 5-Carboxylcytosine through Its CXXC Domain and Is a Potential Guardian against Neurodegeneration Fulltext Access 13 Pages 2016
Transcription Factor NFIB Is a Driver of Small Cell Lung Cancer Progression in Mice and Marks Metastatic Disease in Patients Fulltext Access 13 Pages 2016
Insulin-like Signaling Promotes Glial Phagocytic Clearance of Degenerating Axons through Regulation of Draper Fulltext Access 13 Pages 2016
PAPERCLIP Identifies MicroRNA Targets and a Role of CstF64/64tau in Promoting Non-canonical poly(A) Site Usage Fulltext Access 13 Pages 2016
Enhanced Transcriptional Activity and Mitochondrial Localization of STAT3 Co-induce Axon Regrowth in the Adult Central Nervous System Fulltext Access 13 Pages 2016
ERRα-Regulated Lactate Metabolism Contributes to Resistance to Targeted Therapies in Breast Cancer Fulltext Access 13 Pages 2016
Leukemogenic MLL-ENL Fusions Induce Alternative Chromatin States to Drive a Functionally Dichotomous Group of Target Genes Fulltext Access 13 Pages 2016
Dysregulation of miRNA-9 in a Subset of Schizophrenia Patient-Derived Neural Progenitor Cells Fulltext Access 13 Pages 2016
Polarizing the Neuron through Sustained Co-expression of Alternatively Spliced Isoforms Fulltext Access 13 Pages 2016
Human iPSC-Derived Immature Astroglia Promote Oligodendrogenesis by Increasing TIMP-1 Secretion Fulltext Access 13 Pages 2016
Tet Enzymes Regulate Telomere Maintenance and Chromosomal Stability of Mouse ESCs Fulltext Access 13 Pages 2016
Translational Capacity of a Cell Is Determined during Transcription Elongation via the Ccr4-Not Complex Fulltext Access 13 Pages 2016
TREX1 Knockdown Induces an Interferon Response to HIV that Delays Viral Infection in Humanized Mice Fulltext Access 13 Pages 2016
Improved Ribosome-Footprint and mRNA Measurements Provide Insights into Dynamics and Regulation of Yeast Translation Fulltext Access 13 Pages 2016
Bio-protective microbial agents from rhizosphere eco-systems trigger plant defense responses provide protection against sheath blight disease in rice (Oryza sativa L.) Fulltext Access 13 Pages 2016
Screening and modes of action of antagonistic bacteria to control the fungal pathogen Phaeomoniella chlamydospora involved in grapevine trunk diseases Fulltext Access 13 Pages 2016
Phytogenic synthesis of silver nanoparticles, optimization and evaluation of in vitro antifungal activity against human and plant pathogens Fulltext Access 13 Pages 2016
Structural Insights into Divalent Cation Modulations of ATP-Gated P2X Receptor Channels Fulltext Access 13 Pages 2016
Ampullary Cancers Harbor ELF3 Tumor Suppressor Gene Mutations and Exhibit Frequent WNT Dysregulation Fulltext Access 13 Pages 2016
Mps1 Mediated Phosphorylation of Hsp90 Confers Renal Cell Carcinoma Sensitivity and Selectivity to Hsp90 Inhibitors Fulltext Access 13 Pages 2016
Information Coding through Adaptive Gating of Synchronized Thalamic Bursting Fulltext Access 13 Pages 2016
Porcupine Controls Hippocampal AMPAR Levels, Composition, and Synaptic Transmission Fulltext Access 13 Pages 2016
The 11S Proteasome Subunit PSME3 Is a Positive Feedforward Regulator of NF-κB and Important for Host Defense against Bacterial Pathogens Fulltext Access 13 Pages 2016
The Gut Epithelial Receptor LRRC19 Promotes the Recruitment of Immune Cells and Gut Inflammation Fulltext Access 13 Pages 2016
MCUR1 Is a Scaffold Factor for the MCU Complex Function and Promotes Mitochondrial Bioenergetics Fulltext Access 13 Pages 2016
Satb1 Overexpression Drives Tumor-Promoting Activities in Cancer-Associated Dendritic Cells Fulltext Access 13 Pages 2016
Genome-wide Analysis Identifies Bcl6-Controlled Regulatory Networks during T Follicular Helper Cell Differentiation Fulltext Access 13 Pages 2016
An ER-Localized SNARE Protein Is Exported in Specific COPII Vesicles for Autophagosome Biogenesis Fulltext Access 13 Pages 2016
The P72R Polymorphism of p53 Predisposes to Obesity and Metabolic Dysfunction Fulltext Access 13 Pages 2016
CARMA3 Is a Host Factor Regulating the Balance of Inflammatory and Antiviral Responses against Viral Infection Fulltext Access 13 Pages 2016
Genome-wide RNAi Screen Identifies Cohesin Genes as Modifiers of Renewal and Differentiation in Human HSCs Fulltext Access 13 Pages 2016
Burst-Dependent Bidirectional Plasticity in the Cerebellum Is Driven by Presynaptic NMDA Receptors Fulltext Access 13 Pages 2016
Asymmetric Inheritance of Aggregated Proteins and Age Reset in Yeast Are Regulated by Vac17-Dependent Vacuolar Functions Fulltext Access 13 Pages 2016
Activation of CDK4 Triggers Development of Non-alcoholic Fatty Liver Disease Fulltext Access 13 Pages 2016
A Role for Timp3 in Microbiota-Driven Hepatic Steatosis and Metabolic Dysfunction Fulltext Access 13 Pages 2016
Dopamine Autoreceptor Regulation of a Hypothalamic Dopaminergic Network Fulltext Access 13 Pages 2016
RBPJ Controls Development of Pathogenic Th17 Cells by Regulating IL-23 Receptor Expression Fulltext Access 13 Pages 2016
NKp80 Defines a Critical Step during Human Natural Killer Cell Development Fulltext Access 13 Pages 2016
Frizzled-Induced Van Gogh Phosphorylation by CK1ε Promotes Asymmetric Localization of Core PCP Factors in Drosophila Fulltext Access 13 Pages 2016
Compartmentalized Epidermal Activation of β-Catenin Differentially Affects Lineage Reprogramming and Underlies Tumor Heterogeneity Fulltext Access 13 Pages 2016
The SNARE VAMP7 Regulates Exocytic Trafficking of Interleukin-12 in Dendritic Cells Fulltext Access 13 Pages 2016
Saturated Fatty Acids Engage an IRE1α-Dependent Pathway to Activate the NLRP3 Inflammasome in Myeloid Cells Fulltext Access 13 Pages 2016
RUNX2 Mediates Plasmacytoid Dendritic Cell Egress from the Bone Marrow and Controls Viral Immunity Fulltext Access 13 Pages 2016
A Polymorphic Antioxidant Response Element Links NRF2/sMAF Binding to Enhanced MAPT Expression and Reduced Risk of Parkinsonian Disorders Fulltext Access 13 Pages 2016
Selective In Vitro Propagation of Nephron Progenitors Derived from Embryos and Pluripotent Stem Cells Fulltext Access 13 Pages 2016
A Unique Class of Neural Progenitors in the Drosophila Optic Lobe Generates Both Migrating Neurons and Glia Fulltext Access 13 Pages 2016
Developmental Origin of Oligodendrocyte Lineage Cells Determines Response to Demyelination and Susceptibility to Age-Associated Functional Decline Fulltext Access 13 Pages 2016
Functional Characterization of DNA Methylation in the Oligodendrocyte Lineage Fulltext Access 13 Pages 2016
A c-Myc/miR17-92/Pten Axis Controls PI3K-Mediated Positive and Negative Selection in B Cell Development and Reconstitutes CD19 Deficiency Fulltext Access 13 Pages 2016
Leader Cells Define Directionality of Trunk, but Not Cranial, Neural Crest Cell Migration Fulltext Access 13 Pages 2016
Discovery of a Small-Molecule BMP Sensitizer for Human Embryonic Stem Cell Differentiation Fulltext Access 13 Pages 2016
Mitotic Exit Function of Polo-like Kinase Cdc5 Is Dependent on Sequential Activation by Cdk1 Fulltext Access 13 Pages 2016
The lncRNA SLNCR1 Mediates Melanoma Invasion through a Conserved SRA1-like Region Fulltext Access 13 Pages 2016
Defining the Minimal Factors Required for Erythropoiesis through Direct Lineage Conversion Fulltext Access 13 Pages 2016
Two Mutually Exclusive Local Chromatin States Drive Efficient V(D)J Recombination Fulltext Access 13 Pages 2016
CYLD Proteolysis Protects Macrophages from TNF-Mediated Auto-necroptosis Induced by LPS and Licensed by Type I IFN Fulltext Access 13 Pages 2016
A Small Molecule RAS-Mimetic Disrupts RAS Association with Effector Proteins to Block Signaling Fulltext Access 13 Pages 2016
Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions Fulltext Access 13 Pages 2016
Mycobacterial WhiB6 Differentially Regulates ESX-1 and the Dos Regulon to Modulate Granuloma Formation and Virulence in Zebrafish Fulltext Access 13 Pages 2016
Autophagy Promotes Focal Adhesion Disassembly and Cell Motility of Metastatic Tumor Cells through the Direct Interaction of Paxillin with LC3 Fulltext Access 13 Pages 2016
Afferent Inputs to Neurotransmitter-Defined Cell Types in the Ventral Tegmental Area Fulltext Access 13 Pages 2016
In Vivo HIV-1 Cell-to-Cell Transmission Promotes Multicopy Micro-compartmentalized Infection Fulltext Access 13 Pages 2016
Negative Selection and Chromosome Instability Induced by Mad2 Overexpression Delay Breast Cancer but Facilitate Oncogene-Independent Outgrowth Fulltext Access 13 Pages 2016
RECQL4 Promotes DNA End Resection in Repair of DNA Double-Strand Breaks Fulltext Access 13 Pages 2016
Neutrophil-Derived IL-1β Impairs the Efficacy of NF-κB Inhibitors against Lung Cancer Fulltext Access 13 Pages 2016
Defects in the CAPN1 Gene Result in Alterations in Cerebellar Development and Cerebellar Ataxia in Mice and Humans Fulltext Access 13 Pages 2016
Cortical Polarity of the RING Protein PAR-2 Is Maintained by Exchange Rate Kinetics at the Cortical-Cytoplasmic Boundary Fulltext Access 13 Pages 2016
Autoinhibition of a Neuronal Kinesin UNC-104/KIF1A Regulates the Size and Density of Synapses Fulltext Access 13 Pages 2016
Genetic Disruption of Arc/Arg3.1 in Mice Causes Alterations in Dopamine and Neurobehavioral Phenotypes Related to Schizophrenia Fulltext Access 13 Pages 2016
Flexible analysis of digital PCR experiments using generalized linear mixed models Fulltext Access 13 Pages 2016
PML at Mitochondria-Associated Membranes Is Critical for the Repression of Autophagy and Cancer Development Fulltext Access 13 Pages 2016
ATRIP Deacetylation by SIRT2 Drives ATR Checkpoint Activation by Promoting Binding to RPA-ssDNA Fulltext Access 13 Pages 2016
Centrosome-Dependent Bypass of the DNA Damage Checkpoint by the Polo Kinase Cdc5 Fulltext Access 13 Pages 2016
Synaptophysin 1 Clears Synaptobrevin 2 from the Presynaptic Active Zone to Prevent Short-Term Depression Fulltext Access 13 Pages 2016
Zebrafish Embryonic Lipidomic Analysis Reveals that the Yolk Cell Is Metabolically Active in Processing Lipid Fulltext Access 13 Pages 2016
Presenilin 2 Modulates Endoplasmic Reticulum-Mitochondria Coupling by Tuning the Antagonistic Effect of Mitofusin 2 Fulltext Access 13 Pages 2016
Ecto-ATPase CD39 Inactivates Isoprenoid-Derived Vγ9Vδ2 T Cell Phosphoantigens Fulltext Access 13 Pages 2016