Dibromomethane as one-carbon source in organic synthesis: total synthesis of (±)- and (â)-methylenolactocin Fulltext Access 11 Pages 2005
meso-Tetraaryl-7,8-diol-21,23-dithiachlorins and their pyrrole-modified derivatives: a spectroscopic comparison to their aza-analogues Fulltext Access 11 Pages 2005
Orthogonality and compatibility between Tsc and Fmoc amino-protecting groups Fulltext Access 11 Pages 2005
Photo-irradiation of α-halo carbonyl compounds: a novel synthesis of α-hydroxy- and α,αâ²-dihydroxyketones Fulltext Access 11 Pages 2005
Synthesis of cis bis-β-lactams via Staudinger cycloaddition reaction using C2-symmetric 1,2-diamines Fulltext Access 11 Pages 2005
Asymmetric palladium-catalyzed annulation of benzene-1,2-diol and racemic secondary propargylic carbonates bearing two different substituents Fulltext Access 11 Pages 2005
Synthesis of the end-capped 5-(N,N-dimethylamino)naphthyl-1-ethynyl derivatives and their 1,4-di[5-(N,N-dimethylamino)naphthyl]-1,3-butadiynes: anti rotamer structure Fulltext Access 11 Pages 2005
Dde-protected PNA monomers, orthogonal to Fmoc, for the synthesis of PNA-peptide conjugates Fulltext Access 11 Pages 2005
Stereocontrolled palladium(0)-catalyzed preparation of unsaturated azidosugars: an easy access to 2- and 4-aminoglycosides Fulltext Access 11 Pages 2005
Experimental and theoretical FMO interaction studies of the Diels-Alder reaction of 5-acetyl-3-methythio-1,2,4-triazine with cyclic enamines Fulltext Access 11 Pages 2005
Proton affinities of ketones, vicinal diketones and α-keto esters: a computational study Fulltext Access 11 Pages 2005
Stereochemical course of the reductive spiroannulations of N-Boc and N-benzyl 2-cyanopiperidines Fulltext Access 11 Pages 2005
1,2,3-Triazoles and related glycoconjugates as new glycosidase inhibitors Fulltext Access 11 Pages 2005
Structure-driven design and synthesis of chiral dioxocyclam derivatives Fulltext Access 11 Pages 2005
Application of directed metalation in synthesis. Part 8: Interesting example of chemoselectivity in the synthesis of thioaurones and hydroxy ketones and a novel anionic ortho-Fries rearrangement used as a tool in the synthesis of thienopyranones and thiaf Fulltext Access 11 Pages 2005
Asymmetric synthesis using catalysts containing multiple stereogenic centres and a trans-1,2-diaminocyclohexane core; reversal of predominant enantioselectivity upon N-alkylation Fulltext Access 11 Pages 2005
Transient Structural Disorder as a Facilitator of Protein-Ligand Binding: Native H/D Exchange-Mass Spectrometry Study of Cellular Retinoic Acid Binding Protein I Fulltext Access 11 Pages 2005
Mass Spectral Fragmentation of the Intravenous Anesthetic Propofol and Structurally Related Phenols Fulltext Access 11 Pages 2005
Comparison of Highly-Fluorinated Chloroformates as Direct Aqueous Sample Derivatizing Agents for Hydrophilic Analytes and Drinking-Water Disinfection By-Products Fulltext Access 11 Pages 2005
Epoxidation of α,β-unsaturated acids catalyzed by tungstate (VI) or molybdate (VI) in aqueous solvents: a specific direct oxygen transfer mechanism Fulltext Access 11 Pages 2005
Diels-Alder reactions of highly pyramidalized tricyclo[3.3.0.03,7]oct-1(5)-ene derivatives: further chemistry of pentacyclo[6.4.0.02,10.03,7.04,9]dodeca-5,8,11-triene Fulltext Access 11 Pages 2005
Synthesis of novel N-methylated thiazole-based cyclic octa- and dodecapeptides Fulltext Access 11 Pages 2005
Synthesis of the necine bases (±)-macronecine and (±)-supinidine via an aza-ene reaction and allylsilane induced ring closure Fulltext Access 11 Pages 2005
Evaluation of ethyl 2-carbomethoxyethenesulfinates as 2-hydroxymethyl enethiol equivalents in the Diels-Alder reaction Fulltext Access 11 Pages 2005
Charge density analysis of some processes involving intramolecular hydrogen transfer Fulltext Access 11 Pages 2005
The preparation and some chemistry of 2,2-dimethyl-1,2-dihydroquinolines Fulltext Access 11 Pages 2005
Self-assembly of a new series of quadruply hydrogen bonded heterotrimers driven by the donor-acceptor interaction Fulltext Access 11 Pages 2005
1-Aryl-4-(4-succinimidobutyl)piperazines and their conformationally constrained analogues: synthesis, binding to serotonin (5-HT1A, 5-HT2A, 5-HT7), α1-adrenergic, and dopaminergic D2 receptors, and in vivo 5-HT1A functional characteristics Fulltext Access 11 Pages 2005
Molecular docking and 3D-QSAR studies on the binding mechanism of statine-based peptidomimetics with β-secretase Fulltext Access 11 Pages 2005
Novel acetylcholinesterase inhibitor as increasing agent on rhythmic bladder contractions: SAR of 8-{3-[1-(3-fluorobenzyl)piperidin-4-yl]propanoyl}-1,2,5,6-tetrahydro-4H-pyrrolo[3,2,1-ij]quinolin-4-one (TAK-802) and related compounds Fulltext Access 11 Pages 2005
Investigations of linker structure on the potency of a series of bidentate protein tyrosine phosphatase inhibitors Fulltext Access 11 Pages 2005
Cytotoxicities, cell cycle and caspase evaluations of 1,6-diaryl-3(Z)-hexen-1,5-diynes, 2-(6-aryl-3(Z)-hexen-1,5-diynyl)anilines and their derivatives Fulltext Access 11 Pages 2005
Novel anellated pyrazoloquinolin-3-ones: synthesis and in vitro BZR activity Fulltext Access 11 Pages 2005
Biphenylquinuclidines as inhibitors of squalene synthase and growth of parasitic protozoa Fulltext Access 11 Pages 2005
Synthesis and evaluation of sphingoid analogs as inhibitors of sphingosine kinases Fulltext Access 11 Pages 2005
Structure–activity relationships of tyrosinase inhibitory combinatorial library of 2,5-disubstituted-1,3,4-oxadiazole analogues Fulltext Access 11 Pages 2005
Chiral NADH model systems functionalized with Zn(II)-cyclen as flavin binding site Fulltext Access 11 Pages 2005
Design and synthesis of non-hydroxamate histone deacetylase inhibitors: identification of a selective histone acetylating agent Fulltext Access 11 Pages 2005
Exploration of a binding mode of indole amide analogues as potent histone deacetylase inhibitors and 3D-QSAR analyses Fulltext Access 11 Pages 2005
The study on the interaction between seryl-histidine dipeptide and proteins by circular dichroism and molecular modeling Fulltext Access 11 Pages 2005
Fluorinated phenylcyclopropylamines. Part 4: Effects of aryl substituents and stereochemistry on the inhibition of monoamine oxidases by 1-aryl-2-fluoro-cyclopropylamines Fulltext Access 11 Pages 2005
Synthesis, structural identification, and ligand binding of tropane ring analogs of paroxetine and an unexpected aza-bicyclo[3.2.2]nonane rearrangement product Fulltext Access 11 Pages 2005
Novel cyclosporin derivatives featuring enhanced skin penetration despite increased molecular weight Fulltext Access 11 Pages 2005
Genistein derivatives as selective estrogen receptor modulators: Sonochemical synthesis and in vivo anti-osteoporotic action Fulltext Access 11 Pages 2005
Synthesis and glycosidase inhibitory activity of new penta-substituted C8-glycomimetics Fulltext Access 11 Pages 2005
Electron depleted bis(methylene)cyclobutenes: sulfinyl and sulfonyl substitution Fulltext Access 11 Pages 2005
Accurate molecular weight measurements of nucleoside phosphoramidites: a suitable matrix of mass spectrometry Fulltext Access 11 Pages 2005
Microwave mediated synthesis of spiro-(indoline-isoxazolidines): mechanistic study and biological activity evaluation Fulltext Access 11 Pages 2005
Versatile strategies for the solid phase synthesis of small heterocyclic scaffolds: [1,3,4]-thiadiazoles and [1,3,4]-oxadiazoles Fulltext Access 11 Pages 2005
Synthesis of ferrocenylcarbodiimide as a convenient electrochemically active labeling reagent for nucleic acids Fulltext Access 11 Pages 2005
New acyclic receptors containing pyridazine units. The influence of Ï-stacking on the selective transport of lipophilic phenethylamines Fulltext Access 11 Pages 2005
2,2,6,6-Tetramethylcyclohexanethione S-methylide, a highly hindered thiocarbonyl ylide: two-step cycloadditions Fulltext Access 11 Pages 2005
Synthesis of regioselectively 18O-labelled chlorophyll derivatives at the 31- and/or 131-positions through one-pot exchange of carbonyl oxygen atoms Fulltext Access 11 Pages 2005
Deracemisation of aryl substituted α-hydroxy esters using Candida parapsilosis ATCC 7330: effect of substrate structure and mechanism Fulltext Access 11 Pages 2005
Synthesis of the insect antifeedant CDE molecular fragment of 12-ketoepoxyazadiradione and related compounds Fulltext Access 11 Pages 2005
Efficient chemoselective deprotection of silyl ethers using catalytic 1-chloroethyl chloroformate in methanol Fulltext Access 11 Pages 2005
Mapping Protein Interfaces by a Trifunctional Cross-Linker Combined with MALDI-TOF and ESI-FTICR Mass Spectrometry Fulltext Access 11 Pages 2005
Synthesis of multivalent neoglycoconjugates by 1,3 dipolar cycloaddition of nitrile oxides and alkynes and evaluation of their lectin-binding affinities Fulltext Access 11 Pages 2005
Microwave-assisted organic synthesis: scale-up of palladium-catalyzed aminations using single-mode and multi-mode microwave equipment Fulltext Access 11 Pages 2005
Atom-transfer radical reactions catalyzed by a coordinatively unsaturated diruthenium amidinate, [(η5-C5Me5)Ru(μ2-i-PrNC(Me)Ni-Pr)Ru(η5-C5Me5)]+ Fulltext Access 11 Pages 2005
Design, synthesis and biological evaluation of novel 1α,25-dihydroxyvitamin D3 analogues possessing aromatic ring on 2α-position Fulltext Access 11 Pages 2005
An unexpected highly diastereoselective double Baylis-Hillman reaction of per- (or poly)fluorophenyl aromatic aldimines with methyl vinyl ketone Fulltext Access 11 Pages 2005
Investigating direct routes to an advanced intermediate for the synthesis of C-20 diterpene alkaloids Fulltext Access 11 Pages 2005
Enantioselective synthesis of axially chiral 1-(1-naphthyl)isoquinolines and 2-(1-naphthyl)pyridines through sulfoxide ligand coupling reactions Fulltext Access 11 Pages 2005
Synthesis of 4,8-anhydro-d-glycero-d-ido-nonanitol 1,6,7-trisphosphate as a novel IP3 receptor ligand using a stereoselective radical cyclization reaction based on a conformational restriction strategy Fulltext Access 11 Pages 2005
Regioselective opening of an oxirane system with trifluoroacetic anhydride. A general method for the synthesis of 2-monoacyl- and 1,3-symmetrical triacylglycerols Fulltext Access 11 Pages 2005
Stereoselective synthesis of new modified conformationally constrained l-tyrosine analogue with potential applications to SH2 domain ligands Fulltext Access 11 Pages 2005
Syntheses of (±)-thuriferic acid ethyl ester, its analogues and (±)-picropodophyllone Fulltext Access 11 Pages 2005