Synthesis of a library of chiral α-amino acid-based borate counteranions and their application to copper catalyzed olefin cyclopropanation Fulltext Access 11 Pages 2005
Palladium-catalysed C-C coupling reactions in the enantioselective synthesis of 2,4-disubstituted 4,5-dehydropiperidines using galactosylamine as a stereodifferentiating auxiliary Fulltext Access 11 Pages 2005
The design and synthesis of novel anomeric hydroperoxides: influence of the carbohydrate residue in the enantioselective epoxidation of quinones Fulltext Access 11 Pages 2005
Synthesis and characterisation of hexa- and tetrasaccharide mimics from acetobromomaltotriose and acetobromomaltose, and of C-disaccharide mimics from acetobromoglucose, obtained by electrochemical reduction on silver Fulltext Access 11 Pages 2005
Resolution of synthetically useful myo-inositol derivatives using the chiral auxiliary O-acetylmandelic acid Fulltext Access 11 Pages 2005
Immunogens from a synthetic hexasaccharide fragment of the O-SP of Vibrio cholerae O:1, serotype Ogawa Fulltext Access 11 Pages 2005
Synthesis of C-glycosyl amino acids: scope and limitations of the tandem Tebbe/Claisen approach Fulltext Access 11 Pages 2005
Diastereocontrolled multicomponent pathway to 3,4-heterocycle-annulated tetrahydro-β-carbolines Fulltext Access 11 Pages 2005
Stereoselective syntheses of pharmaceutically relevant chiral tetrahydrofurans from (S)- and (R)-glyceraldehyde derivatives Fulltext Access 11 Pages 2005
Synthesis of d-mannose-based azacrown ethers and their application in enantioselective reactions Fulltext Access 11 Pages 2005
([2]Paracyclo[2](5,8)quinolinophan-2-yl)carbinols as catalysts for diethylzinc addition to aldehydes: cooperative effects of planar and central chirality on the asymmetric induction Fulltext Access 11 Pages 2005
Selective sialylation of 2,3-di-O-(β-d-galactopyranosyl)-d-galactose catalyzed by Trypanosoma cruzi trans-sialidase Fulltext Access 11 Pages 2005
Synthesis of chiral sultams and their application as chiral auxiliaries in an asymmetric Diels-Alder reaction Fulltext Access 11 Pages 2005
An Automated Method for the Analysis of Stable Isotope Labeling Data in Proteomics Fulltext Access 11 Pages 2005
Proton Affinity of β-Oxalylaminoalanine (BOAA): Incorporation of Direct Entropy Correction into the Single-Reference Kinetic Method Fulltext Access 11 Pages 2005
SO2â· Electron Transfer Ion/Ion Reactions with Disulfide Linked Polypeptide Ions Fulltext Access 11 Pages 2005
Evaluation of Ion Mobility Spectroscopy for Determining Charge-Solvated versus Salt-Bridge Structures of Protonated Trimers Fulltext Access 11 Pages 2005
Electrospray Ionization Mass Spectrometry and Ion Mobility Analysis of the 20S Proteasome Complex Fulltext Access 11 Pages 2005
Increased Fragmentation Efficiency of Ions in a Low Pressure Linear Ion Trap with an Added dc Octopole Field Fulltext Access 11 Pages 2005
The Utility of Accurate Mass and LC Elution Time Information in the Analysis of Complex Proteomes Fulltext Access 11 Pages 2005
Improvement of Biological Time-of-Flight-Secondary Ion Mass Spectrometry Imaging with a Bismuth Cluster Ion Source Fulltext Access 11 Pages 2005
Rapid Method for Quantifying the Extent of Methionine Oxidation in Intact Calmodulin Fulltext Access 11 Pages 2005
Multidimensional Separations of Ubiquitin Conformers in the Gas Phase: Relating Ion Cross Sections to H/D Exchange Measurements Fulltext Access 11 Pages 2005
Identification of peptide ligands for malignancy- and growth-regulating galectins using random phage-display and designed combinatorial peptide libraries Fulltext Access 11 Pages 2005
Synthesis and biological relationships of 3â²,6-substituted 2-phenyl-4-quinolone-3-carboxylic acid derivatives as antimitotic agents Fulltext Access 11 Pages 2005
Synthesis and in vitro binding of N-phenyl piperazine analogs as potential dopamine D3 receptor ligands Fulltext Access 11 Pages 2005
Photocontrol of nitric oxide production in cell culture using a caged isoform selective inhibitor Fulltext Access 11 Pages 2005
Oligosaccharides as inhibitors of mycobacterial arabinosyltransferases. Di- and trisaccharides containing C-3 modified arabinofuranosyl residues Fulltext Access 11 Pages 2005
Perfluorinated markers for hypoxia detection: synthesis of sulfur-containing precursors and [18F]-labelling Fulltext Access 11 Pages 2005
Predicting multiple drugs side effects with a general drug-target interaction thermodynamic Markov model Fulltext Access 11 Pages 2005
Exploring human adenosine A3 receptor complementarity and activity for adenosine analogues modified in the ribose and purine moiety Fulltext Access 11 Pages 2005
Cardioprotective activity of melatonin and its novel synthesized derivatives on doxorubicin-induced cardiotoxicity Fulltext Access 11 Pages 2005
Stereochemical influence on lipase-mediated hydrolysis and biological activity of stampidine and other stavudine phosphoramidates Fulltext Access 11 Pages 2005
α-Glucosidase inhibition of 6-hydroxyflavones. Part 3: Synthesis and evaluation of 2,3,4-trihydroxybenzoyl-containing flavonoid analogs and 6-aminoflavones as α-glucosidase inhibitors Fulltext Access 11 Pages 2005
Synthesis and potent antimicrobial activity of some novel methyl or ethyl 1H-benzimidazole-5-carboxylates derivatives carrying amide or amidine groups Fulltext Access 11 Pages 2005
Cyclization of the Substituted N-(Ortho-Cyclopropylphenyl)-Nâ²-Aryl Ureas and Thioureas in the Gas Phase and Solution Fulltext Access 11 Pages 2005
N-Oxide analogs of WAY-100635: new high affinity 5-HT1A receptor antagonists Fulltext Access 11 Pages 2005
Design, synthesis, and evaluation of novel bifunctional iron-chelators as potential agents for neuroprotection in Alzheimer's, Parkinson's, and other neurodegenerative diseases Fulltext Access 11 Pages 2005
2-Aryl-8-chloro-1,2,4-triazolo[1,5-a]quinoxalin-4-amines as highly potent A1 and A3 adenosine receptor antagonists Fulltext Access 11 Pages 2005
Novel diterpenoids with potent inhibitory activity against endothelium cell HMEC and cytotoxic activities from a well-known TCM plant Daphne genkwa Fulltext Access 11 Pages 2005
Expression, purification, and enzymatic characterization of the dual specificity mitogen-activated protein kinase phosphatase, MKP-4 Fulltext Access 11 Pages 2005
Rational design of novel diketoacid-containing ferrocene inhibitors of HIV-1 integrase Fulltext Access 11 Pages 2005
Evidence for the formation of Michael adducts from reactions of (E,E)-muconaldehyde with glutathione and other thiols Fulltext Access 11 Pages 2005
Functional significance of Glu-77 and Tyr-137 within the active site of isoaspartyl dipeptidase Fulltext Access 11 Pages 2005
Effects of solvent polarity and solvent viscosity on the fluorescent properties of molecular rotors and related probes Fulltext Access 11 Pages 2005
Production of (R)-chiral alcohols by a hydrogen-transfer bioreduction with NADH-dependent Leifsonia alcohol dehydrogenase (LSADH) Fulltext Access 11 Pages 2005
Combined NMR-crystallographic and modelling investigation of the inclusion of molsidomine into α-, β- and γ-cyclodextrins Fulltext Access 11 Pages 2005
Design and synthesis of novel androgen receptor antagonists with sterically bulky icosahedral carboranes Fulltext Access 11 Pages 2005
New potent 5-substituted benzofuroxans as inhibitors of Trypanosoma cruzi growth: Quantitative structure–activity relationship studies Fulltext Access 11 Pages 2005
QSAR studies on 1-phenylbenzimidazoles as inhibitors of the platelet-derived growth factor Fulltext Access 11 Pages 2005
Synthesis and antibacterial activity of new N-linked 5-triazolylmethyl oxazolidinones Fulltext Access 11 Pages 2005
Synthetic modification of the 2-oxypropionic acid moiety in 2-{4-[(7-chloro-2-quinoxalinyl)oxy]phenoxy}propionic acid (XK469), and consequent antitumor effects. Part 4 Fulltext Access 11 Pages 2005
Lobelane analogues as novel ligands for the vesicular monoamine transporter-2 Fulltext Access 11 Pages 2005
Synthesis of glycoporphyrin derivatives and their antiviral activity against herpes simplex virus types 1 and 2 Fulltext Access 11 Pages 2005
Methyllycaconitine analogues have mixed antagonist effects at nicotinic acetylcholine receptors Fulltext Access 11 Pages 2005
Determination of absolute configuration using vibrational circular dichroism spectroscopy: phenyl glycidic acid derivatives obtained via asymmetric epoxidation using oxone and a keto bile acid Fulltext Access 11 Pages 2005
Synthesis of enantiomerically pure cis- and trans-cyclopentane analogues of phenylalanine Fulltext Access 11 Pages 2005
Biomimetic synthesis of acid-sensitive (−)- and (+)-caparrapi oxides, (−)- and (+)-8-epicaparrapi oxides, and (+)-dysifragin induced by artificial cyclases Fulltext Access 11 Pages 2005
Asymmetric inverse electron-demand 1,3-dipolar cycloaddition of ynolates with a chiral nitrone derived from l-serine leading to β-amino acid derivatives Fulltext Access 11 Pages 2005
Synthesis of (3S,3S′,4S,4S′)-1,1′-ethylenedipyrrolidine-3,3′,4,4′-tetraol and related diamino diols: donor–acceptor hydrogen-bonding motifs of the C2 symmetric 3,4-dihydroxypyrrolidine unit Fulltext Access 11 Pages 2005
Chiral α-branched mono phosphine auxiliaries, reversal of sense of asymmetric induction upon substitution Fulltext Access 11 Pages 2005
A short and highly stereoselective route to polyhydroxy-perhydroazaazulenes via a C-(d-galacto-pentopyranos-5-yl)isoxazolidine Fulltext Access 11 Pages 2005
Stereochemical consequences of the use of chiral N-phosphoryl oxazolidinones in the attempted kinetic resolution of bromomagnesium alkoxides Fulltext Access 11 Pages 2005
Reduced collagen cross links: the first synthesis of all the possible (2S,2′S)-stereoisomers of 5-hydroxylysinonorleucine and of 5,5′-dihydroxylysinonorleucine in enantiomerically pure form Fulltext Access 11 Pages 2005
Chiral monomeric organorhenium(VII) and organomolybdenum(VI) compounds as catalysts for chiral olefin epoxidation reactions Fulltext Access 11 Pages 2005
Enantiomeric recognition of α-(1-naphthyl)ethylammonium perchlorate by enantiomerically pure dimethylphenazino-18-crown-6 ligand in solid and gas phases Fulltext Access 11 Pages 2005
Synthesis and reductions of (1R,4E,5S)-4-oximino-1,8,8-trimethyl-2-oxabicyclo[3.2.1]octan-3-one Fulltext Access 11 Pages 2005
Lactones 23: Synthesis of cis-fused bicyclic hydroxy lactones with a p-menthane system Fulltext Access 11 Pages 2005
Design, synthesis and in vitro and in vivo antitumor activities of novel β-carboline derivatives Fulltext Access 11 Pages 2005
Oligosaccharide analysis using anion attachment in negative mode electrospray mass spectrometry Fulltext Access 11 Pages 2005
A new charge-associated mechanism to account for the production of fragment ions in the high-energy CID spectra of fatty acids Fulltext Access 11 Pages 2005
Characterization of low molecular weight components of [(ViMe2SiO1/2)x(PhSiO3/2)y(SiO4/2)z], [(ViMe2SiO1/2)x(SiO4/2)y], and [(SiO4/2)x(HO1/2)y(tBuO1/2)z] silsesquioxanes by Electrospray Ionization Fourier Transform Mass Spectrometry (ESI-FTMS) Fulltext Access 11 Pages 2005
Microwave-assisted acid hydrolysis of proteins combined with liquid chromatography MALDI MS/MS for protein identification Fulltext Access 11 Pages 2005
Structural Characterization of the GM1 Ganglioside by Infrared Multiphoton Dissociation, Electron Capture Dissociation, and Electron Detachment Dissociation Electrospray Ionization FT-ICR MS/MS Fulltext Access 11 Pages 2005
Fluorotrimethylsilane Affinities of Anionic Nucleophiles: A Study of Fluoride-Induced Desilylation Fulltext Access 11 Pages 2005
Estimating the sequence complexity of a random oligonucleotide population by using in vitro thermal melting and Cot analyses Fulltext Access 11 Pages 2005
Theoretically predicted structures of plasma membrane Ca2+-ATPase and their susceptibilities to oxidation Fulltext Access 11 Pages 2005
Diastereoselective synthesis of 3,4-disubstituted 5-(p-tolylsulfinyl)-5,6-dehydropiperidin-2-ones: chirality transfer in the enantioselective synthesis of ethyl (+)-(3S,4aS,7aS)-1-oxo-octahydro-1H-cyclopenta[c]pyridine-3-carboxylate Fulltext Access 11 Pages 2005
Synthesis and cytotoxicities of 7-aza rebeccamycin analogues bearing various substituents on the sugar moiety, on the imide nitrogen and on the carbazole framework Fulltext Access 11 Pages 2005
2-Arylidene-4-(4-phenoxy-phenyl)but-3-en-4-olides: Synthesis, reactions and biological activity Fulltext Access 11 Pages 2005
Validation of a histamine H3 receptor model through structure–activity relationships for classical H3 antagonists Fulltext Access 11 Pages 2005
Binding studies and GRIND/ALMOND-based 3D QSAR analysis of benzothiazine type KATP-channel openers Fulltext Access 11 Pages 2005
Hydrophobic and electronic factors in the design of dialkylglycine decarboxylase mimics Fulltext Access 11 Pages 2005
Branched aminoglycosides: Biochemical studies and antibacterial activity of neomycin B derivatives Fulltext Access 11 Pages 2005
Synthesis and initial PET imaging of new potential dopamine D3 receptor radioligands (E)-4,3,2-[11C]methoxy-N-4-(4-(2-methoxyphenyl)piperazin-1-yl)butyl-cinnamoylamides Fulltext Access 11 Pages 2005
Prostate cancer PET bioprobes: Synthesis of [18F]-radiolabeled hydroxyflutamide derivatives Fulltext Access 11 Pages 2005
Chiral anthracene and anthrone templates as stereocontrolling elements in Diels–Alder/retro Diels–Alder sequences Fulltext Access 11 Pages 2005
Metabolism of anthocyanins and their phenolic degradation products by the intestinal microflora Fulltext Access 11 Pages 2005