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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

The reactivity of lactyl-oxythiamin implies the role of the amino-pyrimidine in thiamin catalyzed decarboxylation
Fulltext Access 6 Pages 2016
Protective effect of Theobroma cacao on nitric oxide and endothelin-1 level in endothelial cells induced by plasma from preeclamptic patients: In silico and in vitro studies
Fulltext Access 6 Pages 2016
Comparison of the effect of mefenamic acid and quince on the level of menstrual bleeding and hemoglobin: A randomized controlled clinical trial
Fulltext Access 6 Pages 2016
Application of metabolomics to toxicology of drugs of abuse: A mini review of metabolomics approach to acute and chronic toxicity studies
Fulltext Access 6 Pages 2016
Preliminary evidence suggesting that nonmetallic and metallic nanoparticle devices protect against the effects of environmental electromagnetic radiation by reducing oxidative stress and inflammatory status
Fulltext Access 6 Pages 2016
Effects of Korean herbal medicine on pregnancy outcomes of infertile women aged over 35: A retrospective study
Fulltext Access 6 Pages 2016
Herbal medicine use among patients with type 2 diabetes in Kashan, Iran, 2015
Fulltext Access 6 Pages 2016
Medicinal herbs for cancer patients undergoing chemotherapy in a Brazilian hospital - An exploratory study
Fulltext Access 6 Pages 2016
Herbal remedies and the self-treatment of stress: An Italian survey
Fulltext Access 6 Pages 2016
Pharmacokinetic drug interaction study between overactive bladder drugs mirabegron and tolterodine in Japanese healthy postmenopausal females
Fulltext Access 6 Pages 2016
Effect of isopropyl myristate on the viscoelasticity and drug release of a drug-in-adhesive transdermal patch containing blonanserin
Fulltext Access 6 Pages 2016
Inulin based micelles loaded with curcumin or celecoxib with effective anti-angiogenic activity
Fulltext Access 6 Pages 2016
Catalytic asymmetric addition of aldehydes using organolithium reagents in the presence of commercial available chiral diol ligands
Fulltext Access 6 Pages 2016
Reviewers 2015
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The case for aflatoxins in the causal chain of gallbladder cancer
Fulltext Access 6 Pages 2016
Stress-induced bystander signaling as a possible factor contributing to neuronal excitability and seizure generation/epileptogenesis
Fulltext Access 6 Pages 2016
Allometric Scaling of Therapeutic Monoclonal Antibodies Using Antigen Concentration as a Correction Factor: Application to the Human Clearance Prediction
Fulltext Access 6 Pages 2016
Proton-Coupled Organic Cation Antiporter Contributes to the Hepatic Uptake of Matrine
Fulltext Access 6 Pages 2016
Statistical Analysis of a Method to Predict Drug-Polymer Miscibility
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Essential Fatty Acids as Transdermal Penetration Enhancers
Fulltext Access 6 Pages 2016
Epidermal Growth Factor Receptor-Specific Nanoprobe Biodistribution in Mouse Models
Fulltext Access 6 Pages 2016
Technology, Applications, and Process Challenges of Dual Chamber Systems
Fulltext Access 6 Pages 2016
Virtual implantation and patient-specific simulation for optimization of outcomes in ventricular assist device recipients
Fulltext Access 6 Pages 2016
Radiotherapeutic bandage for the treatment of squamous cell carcinoma of the skin
Fulltext Access 6 Pages 2016
Estimating the Aqueous Solubility of Pharmaceutical Hydrates
Fulltext Access 6 Pages 2016
Enhanced Activity of Topical Hydrocortisone by Competitive Binding of Corticosteroid-Binding Globulin
Fulltext Access 6 Pages 2016
Effects of Carnitine on Valproic Acid Pharmacokinetics in Rats
Fulltext Access 6 Pages 2016
Pharmacodynamics and Systems Pharmacology Approaches to Repurposing Drugs in the Wake of Global Health Burden
Fulltext Access 6 Pages 2016
Technical Decision Making With Higher Order Structure Data: Perspectives on Higher Order Structure Characterization From the Biopharmaceutical Industry
Fulltext Access 6 Pages 2016
Perceptions of Egyptian physicians about drug shortage during political disturbances: Survey in Greater Cairo
Fulltext Access 6 Pages 2016
Reversal of enantioselectivity induced by the achiral part of an organocatalyst in a Diels-Alder reaction
Fulltext Access 6 Pages 2016
Histamine and histamine receptors in Tourette syndrome and other neuropsychiatric conditions
Fulltext Access 6 Pages 2016
Submolecular regulation of cell transformation by deuterium depleting water exchange reactions in the tricarboxylic acid substrate cycle
Fulltext Access 6 Pages 2016
Polystyrene supported benzoylthiourea—pyrrolidine organocatalyst for the enantioselective Michael addition
Fulltext Access 6 Pages 2016
A multidrug cocktail approach attenuates ischemic-type biliary lesions in liver transplantation from non-heart-beating donors
Fulltext Access 6 Pages 2016
A systemic evolutionary approach to cancer: Hepatocarcinogenesis as a paradigm
Fulltext Access 6 Pages 2016
Anthropogenic and temporal components in a complex trigger of type 1 diabetes suggest the active participation of antipyretics
Fulltext Access 6 Pages 2016
Fructose surges damage hepatic adenosyl-monophosphate-dependent kinase and lead to increased lipogenesis and hepatic insulin resistance
Fulltext Access 6 Pages 2016
Role of reduced insulin-stimulated bone blood flow in the pathogenesis of metabolic insulin resistance and diabetic bone fragility
Fulltext Access 6 Pages 2016
Chronic l-menthol-induced browning of white adipose tissue hypothesis: A putative therapeutic regime for combating obesity and improving metabolic health
Fulltext Access 6 Pages 2016
Announcements & Calendar of events
Fulltext Access 6 Pages 2016
Characterization of sprays for thermo-stabilized pneumatic nebulizer
Fulltext Access 6 Pages 2016
Improving the solubility of dexlansoprazole by cocrystallization with isonicotinamide
Fulltext Access 6 Pages 2016
Aliskiren inhibits the renin-angiotensin system in retinal pigment epithelium cells
Fulltext Access 6 Pages 2016
Synthesis and tyrosinase inhibition activity of trans-stilbene derivatives
Fulltext Access 6 Pages 2016
A multi-responsive multicomponent hydrogel with micro-phase separation structure: Synthesis and special drug release
Fulltext Access 6 Pages 2016
Preparation and characterization of polymeric micelles loaded with a potential anticancer prodrug
Fulltext Access 6 Pages 2016
Thalidomide analogues: Tumor necrosis factor-alpha inhibitors and their evaluation as anti-inflammatory agents
Fulltext Access 6 Pages 2016
Effect of food intake and co-administration of placebo self-nanoemulsifying drug delivery systems on the absorption of cinnarizine in healthy human volunteers
Fulltext Access 6 Pages 2016
The future of pharmaceutical manufacturing in the context of the scientific, social, technological and economic evolution
Fulltext Access 6 Pages 2016
Les quinolones et les sulfamides
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Deracemization of 1-phenylethanol via tandem biocatalytic oxidation and reduction
Fulltext Access 6 Pages 2016
Les traitements du cancer du sein
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Asymmetric fluorination of 4-substituted pyrazolones catalyzed by quinine
Fulltext Access 6 Pages 2016
Efficiency of “cyclodextrin-ibuprofen” inclusion complex formation
Fulltext Access 6 Pages 2016
Antileishmanial activity of new thiophene–indole hybrids: Design, synthesis, biological and cytotoxic evaluation, and chemometric studies
Fulltext Access 6 Pages 2016
Synthesis and evaluation of raloxifene derivatives as a selective estrogen receptor down-regulator
Fulltext Access 6 Pages 2016
Preparation, biological evaluation and molecular docking study of imidazolyl dihydropyrimidines as potential Mycobacterium tuberculosis dihydrofolate reductase inhibitors
Fulltext Access 6 Pages 2016
A facile and rapid access to resveratrol derivatives and their radioprotective activity
Fulltext Access 6 Pages 2016
Structure activity relationship, cytotoxicity and evaluation of antioxidant activity of curcumin derivatives
Fulltext Access 6 Pages 2016
Discovery of spirocyclic proline tryptophan hydroxylase-1 inhibitors
Fulltext Access 6 Pages 2016
Design, synthesis and evaluation of the multidrug resistance-reversing activity of pyridine acid esters of podophyllotoxin in human leukemia cells
Fulltext Access 6 Pages 2016
Comparing the efficacy of photodynamic and sonodynamic therapy in non-melanoma and melanoma skin cancer
Fulltext Access 6 Pages 2016
Development of a long-acting intramuscularly injectable formulation with nanosuspension of andrographolide
Fulltext Access 6 Pages 2016
Quantitative Targeted Absolute Proteomics for 28 Transporters in Brush-Border and Basolateral Membrane Fractions of Rat Kidney
Fulltext Access 6 Pages 2016
Photochemical Mechanism of Riboflavin-Induced Degradation of Famotidine and a Suggested Pharmaceutical Strategy for Improving Photostability
Fulltext Access 6 Pages 2016
An Investigation Into Vortioxetine Salts: Crystal Structure, Thermal Stability, and Solubilization
Fulltext Access 6 Pages 2016
The Pro-inflammatory Cytokine Interleukin-6 Regulates Nanoparticle Transport Across Model Follicle-Associated Epithelium Cells
Fulltext Access 6 Pages 2016
Graphical abstract contents listing
Fulltext Access 6 Pages 2016
Evaluation of nuclear imaging potential and photodynamic therapy efficacy of symmetrical and asymmetrical zinc phthalocyanines
Fulltext Access 6 Pages 2016
Application of Three-Dimensionally Printed Probe and Reservoir to Critical Micelle Concentration Determination by Microvolume Surface Tension Measurement
Fulltext Access 6 Pages 2016
Tumor distribution and anti-tumor effect of doxorubicin following intrapulmonary administration to mice with metastatic lung tumor
Fulltext Access 6 Pages 2016
Kinetic solubility and lipophilicity evaluation connecting formulation technology strategy perspective
Fulltext Access 6 Pages 2016
Kinetic resolution of epoxy alcohols with the Sharpless Ti-isopropoxide/tartaric ester complex
Fulltext Access 6 Pages 2016
Contribution to the synthesis of polyhydroxylated indolizidines starting from sugar isothiocyanates
Fulltext Access 6 Pages 2016
Graphical abstract contents listing
Fulltext Access 6 Pages 2016
Pharmaceutical evaluation of atorvastatin calcium tablets available on the Internet: A preliminary investigation of substandard medicines in Japan
Fulltext Access 6 Pages 2016
A novel core–shell chronotherapeutic system for the oral administration of ketoprofen
Fulltext Access 6 Pages 2016
New benzimidazolium-based chiral ionic liquids: synthesis and application in enantioselective sodium borohydride reductions in water
Fulltext Access 6 Pages 2016
Effect of relative air humidity on the flowability of lactose powders
Fulltext Access 6 Pages 2016
Particle Formation and Aggregation of a Therapeutic Protein in Nanobubble Suspensions
Fulltext Access 7 Pages 2016
Effect of Amlodipine, Cilnidipine and Diltiazem on lipid profiles of hypertensive rats fed with high fat diet: A comparative study
Fulltext Access 7 Pages 2016
Modeling Organic Anion-Transporting Polypeptide 1B1 Inhibition to Elucidate Interaction Risks in Early Drug Design
Fulltext Access 7 Pages 2016
Pharmacokinetics and Tissue Distribution of Folate-Decorated Human Serum Albumin Loaded With Nano-Hydroxycamptothecin for Tumor Targeting
Fulltext Access 7 Pages 2016
Protein Nitrogen Determination by Kjeldahl Digestion and Ion Chromatography
Fulltext Access 7 Pages 2016
The pre-clinical characterization of an alpha-emitting sigma-2 receptor targeted radiotherapeutic
Fulltext Access 7 Pages 2016
Preparation and evaluation of the tumor-specific antigen-derived synthetic mucin 1 peptide: A potential candidate for the targeting of breast carcinoma
Fulltext Access 7 Pages 2016
Charge-reversal nanoparticles: novel targeted drug delivery carriers
Fulltext Access 7 Pages 2016
Preparation and evaluation of a phospholipid-based injectable gel for the long term delivery of leuprolide acetaterrh
Fulltext Access 7 Pages 2016
Nose-to-brain delivery of macromolecules mediated by cell-penetrating peptides
Fulltext Access 7 Pages 2016
Three pairs of alkaloid enantiomers from the root of Isatis indigotica
Fulltext Access 7 Pages 2016
Comparison of drug release from liquid crystalline monoolein dispersions and solid lipid nanoparticles using a flow cytometric technique
Fulltext Access 7 Pages 2016
Rôle du pharmacien auprès des patientes atteintes d’un cancer du sein
Fulltext Access 7 Pages 2016
Les traitements de l’arthrose
Fulltext Access 7 Pages 2016
A high-throughput screening assay for eukaryotic elongation factor 2 kinase inhibitors
Fulltext Access 7 Pages 2016
Effect of age on the pharmacokinetics of polymorphic nimodipine in rats after oral administration
Fulltext Access 7 Pages 2016
Copper-64 labeled liposomes for imaging bone marrow
Fulltext Access 7 Pages 2016
Does the mosquito have more of a role in certain cancers than is currently appreciated? - The mosquito cocktail hypothesis
Fulltext Access 7 Pages 2016
Deep venous thrombosis: The valve cusp hypoxia thesis and its incompatibility with modern orthodoxy
Fulltext Access 7 Pages 2016
Early-life stress and reproductive cost: A two-hit developmental model of accelerated aging?
Fulltext Access 7 Pages 2016
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