Quantitative aspects of the analysis of the monoclonal antibody trastuzumab using high-performance liquid chromatography coupled with electrospray mass spectrometry Fulltext Access 7 Pages 2008
Substituent control of DNA binding modes in a series of chalcogenoxanthylium photosensitizers as determined by isothermal titration calorimetry and topoisomerase I DNA unwinding assay Fulltext Access 7 Pages 2008
Synthesis and biological evaluation of a 2-aryl polyhydroxylated pyrrolidine alkaloid-based library Fulltext Access 7 Pages 2008
Synthesis and preliminary biological evaluation of novel pyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as potential agents against A549 lung cancer cells Fulltext Access 7 Pages 2008
A validated reversed phase HPLC method for the determination of process-related impurities in almotriptan malate API Fulltext Access 7 Pages 2008
Development and metrological characterization of quantitative X-ray diffraction phase analysis for the mixtures of clopidogrel bisulphate polymorphs Fulltext Access 7 Pages 2008
Establishment of an HPLC identification system for detection of counterfeit steroidal drugs Fulltext Access 7 Pages 2008
1H NMR-based metabonomic analysis of urine from young spontaneously hypertensive rats Fulltext Access 7 Pages 2008
Polymethoxylated flavones metabolites in rat plasma after the consumption of Fructus aurantii extract: Analysis by liquid chromatography/electrospray ion trap mass spectrometry Fulltext Access 7 Pages 2008
Fourier transform mid-infrared (MIR) and near-infrared (NIR) spectroscopy for rapid quality assessment of Chinese medicine preparation Honghua Oil Fulltext Access 7 Pages 2008
Method development and validation for the simultaneous determination of cinnarizine and co-formulated drugs in pharmaceutical preparations by capillary electrophoresis Fulltext Access 7 Pages 2008
Spectroscopic and chromatographic characterization of triflusal delivery systems prepared by using supercritical impregnation technologies Fulltext Access 7 Pages 2008
Synthesis and biological activity of previtamin D3 analogues with A-ring modifications Fulltext Access 7 Pages 2008
Simultaneous determination and pharmacokinetics of five bufadienolides in rat plasma after oral administration of Chansu extract by SPE-HPLC method Fulltext Access 7 Pages 2008
Quantitative analysis of polypeptide pharmaceuticals by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Fulltext Access 7 Pages 2008
Analysis of iridoid glucosides in Hedyotis diffusa by high-performance liquid chromatography/electrospray ionization tandem mass spectrometry Fulltext Access 7 Pages 2008
Evaluation of the use of UPLC-TOFMS with simultaneous [14C]-radioflow detection for drug metabolite profiling: Application to propranolol metabolites in rat urine Fulltext Access 7 Pages 2008
Electrochemical and spectrometric study of antioxidant activity of pomiferin, isopomiferin, osajin and catalposide Fulltext Access 7 Pages 2008
Stability indicating UPLC method for simultaneous determination of atorvastatin, fenofibrate and their degradation products in tablets Fulltext Access 7 Pages 2008
Evaluation of the European Pharmacopoeia method for control of residual solvents in some antibiotics Fulltext Access 7 Pages 2008
The direct comparison of health and ulcerated stomach tissue: A multiple probe microdialysis sampling approach Fulltext Access 7 Pages 2008
Isolation and structure elucidation of the major photodegradation products of seratrodast Fulltext Access 7 Pages 2008
Quality evaluation of Angelica acutiloba Kitagawa roots by 1H NMR-based metabolic fingerprinting Fulltext Access 7 Pages 2008
Synthesis and immunological evaluation of self-adjuvanting glycolipopeptide vaccine candidates Fulltext Access 7 Pages 2008
SAR study of 2,3,4,14b-tetrahydro-1H-dibenzo[b,f]pyrido[1,2-d][1,4]oxazepines as progesterone receptor agonists Fulltext Access 7 Pages 2008
Probing the structural and topological requirements for CCR2 antagonism: Holographic QSAR for indolopiperidine derivatives Fulltext Access 7 Pages 2008
Identification of a potent new chemotype for the selective inhibition of PDE4 Fulltext Access 7 Pages 2008
Novel N1-substituted 1,3-dihydro-2H-benzimidazol-2-ones as potent non-nucleoside reverse transcriptase inhibitors Fulltext Access 7 Pages 2008
In vitro inhibition of glycogen-degrading enzymes and glycosidases by six-membered sugar mimics and their evaluation in cell cultures Fulltext Access 7 Pages 2008
Synthesis and cytotoxic, anti-inflammatory, and anti-oxidant activities of 2′,5′-dialkoxylchalcones as cancer chemopreventive agents Fulltext Access 7 Pages 2008
Remarkable DNA binding affinity and potential anticancer activity of pyrrolo[2,1-c][1,4]benzodiazepine–naphthalimide conjugates linked through piperazine side-armed alkane spacers Fulltext Access 7 Pages 2008
Structure–activity relationship of flavonoids as influenza virus neuraminidase inhibitors and their in vitro anti-viral activities Fulltext Access 7 Pages 2008
Muscarinic receptor 1 agonist activity of novel N-arylthioureas substituted 3-morpholino arecoline derivatives in Alzheimer’s presenile dementia models Fulltext Access 7 Pages 2008
Fluorescent polycyclic ligands for nitric oxide synthase (NOS) inhibition Fulltext Access 7 Pages 2008
Quality assessment of unfractionated heparin using 1H nuclear magnetic resonance spectroscopy Fulltext Access 7 Pages 2008
Anacardic acid derivatives as inhibitors of glyceraldehyde-3-phosphate dehydrogenase from Trypanosoma cruzi Fulltext Access 7 Pages 2008
Synthesis of new 4-[2-(4-methyl(amino)sulfonylphenyl)-5-trifluoromethyl-2H-pyrazol-3-yl]-1,2,3,6-tetrahydropyridines: A search for novel nitric oxide donor anti-inflammatory agents Fulltext Access 7 Pages 2008
Synthesis of 1-arylpiperazyl-2-phenylcyclopropanes designed as antidopaminergic agents: Cyclopropane-based conformationally restricted analogs of haloperidol Fulltext Access 7 Pages 2008
Antioxidative and thrombolytic TMP nitrone for treatment of ischemic stroke Fulltext Access 7 Pages 2008
New acridone-4-carboxylic acid derivatives as potential inhibitors of Hepatitis C virus infection Fulltext Access 7 Pages 2008
Synthesis and biological evaluation of polymethoxylated 4-heteroarylcoumarins as tubulin assembly inhibitor Fulltext Access 7 Pages 2008
Arabinose 5-phosphate analogues as mechanistic probes for Neisseria meningitidis 3-deoxy-d-manno-octulosonate 8-phosphate synthase Fulltext Access 7 Pages 2008
Dimer of 2,7-diamino-1,8-naphthyridine for the detection of mismatches formed by pyrimidine nucleotide bases Fulltext Access 7 Pages 2008
Synthesis and antimicrobial activity of 2-alkenylchroman-4-ones, 2-alkenylthiochroman-4-ones and 2-alkenylquinol-4-ones Fulltext Access 7 Pages 2008
Development and validation of UPLC method for determination of primaquine phosphate and its impurities Fulltext Access 7 Pages 2008
Method development and validation for the simultaneous determination of meloxicam and pridinol mesylate using RP-HPLC and its application in drug formulations Fulltext Access 7 Pages 2008
Development and validation of a capillary electrophoresis method for the simultaneous determination of impurities of escitalopram including the R-enantiomer Fulltext Access 7 Pages 2008
Enantiomer separation of α-hydroxy acids in high-performance immunoaffinity chromatography Fulltext Access 7 Pages 2008
Potentialities of ITP-CZE method with diode array detection for enantiomeric purity control of dexbrompheniramine in pharmaceuticals Fulltext Access 7 Pages 2008
A capillary zone electrophoresis method for the assay and quality control of mesembrine in Sceletium tablets Fulltext Access 7 Pages 2008
Quantification of carbamazepine, carbamazepine-10,11-epoxide, phenytoin and phenobarbital in plasma samples by stir bar-sorptive extraction and liquid chromatography Fulltext Access 7 Pages 2008
Demonstration of a direct capture immunoaffinity separation for C-reactive protein using a capillary-based microfluidic device Fulltext Access 7 Pages 2008
Molecular structural characteristics as determinants of estrogen receptor selectivity Fulltext Access 7 Pages 2008
Validated flow-injection method for rapid aluminium determination in anti-perspirants Fulltext Access 7 Pages 2008
An LC method for the simultaneous screening of some common counterfeit and sub-standard antibiotics: Validation and uncertainty estimation Fulltext Access 7 Pages 2008
Fast generic chiral separation strategies using electrophoretic and liquid chromatographic techniques Fulltext Access 7 Pages 2008
Development of predictive quantitative retention-activity relationship models of HMG-CoA reductase inhibitors by biopartitioning micellar chromatography Fulltext Access 7 Pages 2008
Prediction of calibration curves in ria of digoxin: Influence of some variables Fulltext Access 7 Pages 2008
Validation of an HPLC–MS method for rociverine tablet dissolution analysis Fulltext Access 7 Pages 2008
Ibuprofen metabolite profiling using a combination of SPE/column-trapping and HPLC–micro-coil NMR Fulltext Access 7 Pages 2008
Evaluation of thermal stability of indinavir sulphate using diffuse reflectance infrared spectroscopy Fulltext Access 7 Pages 2008
Magnesium cation effect on passive diffusion of statin molecules: Molecular chromatography approach Fulltext Access 7 Pages 2008
Photochemical stabilities of some dihydropyridine calcium-channel blockers in powdered pharmaceutical tablets Fulltext Access 7 Pages 2008
Acrolein sequestering ability of the endogenous tripeptide glycyl-histidyl-lysine (GHK): Characterization of conjugation products by ESI-MSn and theoretical calculations Fulltext Access 7 Pages 2008
Analytical method for determination of allylic isoprenols in rat tissues by liquid chromatography/tandem mass spectrometry following chemical derivatization with 3-nitrophtalic anhydride Fulltext Access 7 Pages 2008
Identification of a degradation product in stressed tablets of olmesartan medoxomil by the complementary use of HPLC hyphenated techniques Fulltext Access 7 Pages 2008
Development and validation of a reverse-phase liquid chromatographic method for the assay of lidocaine hydrochloride in alginate-Gantrez® microspheres Fulltext Access 7 Pages 2008
The determination of glycyrrhizic acid in Glycyrrhiza uralensis Fisch. ex DC. (Zhi Gan Cao) root and the dried aqueous extract by LC–DAD Fulltext Access 7 Pages 2008
Measuring the distribution of density and tabletting force in pharmaceutical tablets by chemical imaging Fulltext Access 7 Pages 2008
Identification and characterization of a principal oxidation impurity in clopidogrel drug substance and drug product Fulltext Access 7 Pages 2008
Simultaneous determination of potassium and total fluoride in toothpastes using a SIA system with two potentiometric detectors Fulltext Access 7 Pages 2008
Development of a HPLC method for the determination of antichagasic phenylethenylbenzofuroxans and its major synthetic secondary products in the chemical production processes Fulltext Access 7 Pages 2008
Multimilligram enantioresolution of sulfoxide proton pump inhibitors by liquid chromatography on polysaccharide-based chiral stationary phase Fulltext Access 7 Pages 2008
Development of a discriminating in vitro dissolution method for a poorly soluble NO-donating selective cyclooxygenase-2 inhibitor Fulltext Access 7 Pages 2008
High-throughput reactive oxygen species (ROS) assay: An enabling technology for screening the phototoxic potential of pharmaceutical substances Fulltext Access 7 Pages 2008
HPLC method for the pharmacokinetics and tissue distribution of taspine solution and taspine liposome after intravenous administrations to mice Fulltext Access 7 Pages 2008
The physicochemical properties and the in vivo AChE inhibition of two potential anti-Alzheimer agents, bis(12)-hupyridone and bis(7)-tacrine Fulltext Access 7 Pages 2008
Development and validation of an improved HPLC method for the control of potentially counterfeit isometamidium products Fulltext Access 7 Pages 2008
Determination of ranolazine in human plasma by LC–MS/MS and its application in bioequivalence study Fulltext Access 7 Pages 2008
The development of methodology for clinical measurement of 5-lipoxygenase pathway intermediates from human peripheral blood mononuclear cells Fulltext Access 7 Pages 2008
Capillary electrophoretic method for the simultaneous determination of tetracycline residues in fish samples Fulltext Access 7 Pages 2008
Simultaneous determination of nucleobases, nucleosides and saponins in Panax notoginseng using multiple columns high performance liquid chromatography Fulltext Access 7 Pages 2008
Quantitation of free polyethylene glycol in PEGylated protein conjugate by size exclusion HPLC with refractive index (RI) detection Fulltext Access 7 Pages 2008
Determination of insulin in innovative formulations by means of LC coupled to fluorescence detection Fulltext Access 7 Pages 2008
Simultaneous determination of hydrazinocurcumin and phenol red in samples from rat intestinal permeability studies: HPLC method development and validation Fulltext Access 7 Pages 2008
Optimizing high-performance liquid chromatography method with fluorescence detection for quantification of tamoxifen and two metabolites in human plasma: Application to a clinical study Fulltext Access 7 Pages 2008
Simultaneous analysis of flavonoids from Hypericum japonicum Thunb.ex Murray (Hypericaceae) by HPLC-DAD–ESI/MS Fulltext Access 7 Pages 2008
Study of equilibrium solubility measurement by saturation shake-flask method using hydrochlorothiazide as model compound Fulltext Access 7 Pages 2008
An assessment of the interactions between diclofenac sodium and ammonio methacrylate copolymer using thermal analysis and Raman spectroscopy Fulltext Access 7 Pages 2008
Determination of phenacetin and salophen analgetics in solid binary mixtures with caffeine by infrared linear dichroic and Raman spectroscopy Fulltext Access 7 Pages 2008