QSAR of adenosine A3 receptor antagonist 1,2,4-triazolo[4,3-a]quinoxalin-1-one derivatives using chemometric tools Fulltext Access 7 Pages 2005
Pyrrolo[3,4-c]quinoline-1,3-diones as potent caspase-3 inhibitors. Synthesis and SAR of 2-substituted 4-methyl-8-(morpholine-4-sulfonyl)-pyrrolo[3,4-c]quinoline-1,3-diones Fulltext Access 7 Pages 2005
Iminosugars as glycosyltransferase inhibitors: synthesis of polyhydroxypyrrolidines and their evaluation on chitin synthase activity Fulltext Access 7 Pages 2005
QSAR analysis of thiazole benzenesulfonamide substituted 3-pyridylethanolamines as β3-adrenergic receptor agonist Fulltext Access 7 Pages 2005
Hologram quantitative structure–activity relationships for a series of farnesoid X receptor activators Fulltext Access 7 Pages 2005
Carbonic anhydrase inhibitors: Novel sulfonamides incorporating 1,3,5-triazine moieties as inhibitors of the cytosolic and tumour-associated carbonic anhydrase isozymes I, II and IX Fulltext Access 7 Pages 2005
Potent and orally active non-peptide antagonists of the human melanocortin-4 receptor based on a series of trans-2-disubstituted cyclohexylpiperazines Fulltext Access 7 Pages 2005
Discovery of 4-aryl-4H-chromenes as a new series of apoptosis inducers using a cell- and caspase-based high-throughput screening assay. 2. Structure–activity relationships of the 7- and 5-, 6-, 8-positions Fulltext Access 7 Pages 2005
Synthesis and bladder smooth muscle relaxing properties of substituted 3-amino-4-aryl-(and aralkyl-)cyclobut-3-ene-1,2-diones Fulltext Access 7 Pages 2005
Synthesis and structure–activity relationships of biarylcarboxamide bis-aminopyrrolidine urea derived small-molecule antagonists of the melanin-concentrating hormone receptor-1 (MCH-R1) Fulltext Access 7 Pages 2005
Design, synthesis, and activity of achiral analogs of 2-quinolones and indoles as non-thiol farnesyltransferase inhibitors Fulltext Access 7 Pages 2005
Structural characterization and antimicrobial activity of 1,3-bis(2-benzimidazyl)-2-thiapropane ligand and its Pd(II) and Zn(II) halide complexes Fulltext Access 7 Pages 2005
Oral delivery of G protein-coupled receptor modulators: An explanation for the observed class difference Fulltext Access 7 Pages 2005
P2–P3 conformationally constrained ketoamide-based inhibitors of cathepsin K Fulltext Access 7 Pages 2005
3-Aminomethyl derivatives of 4,11-dihydroxynaphtho[2,3-f]indole-5,10-dione for circumvention of anticancer drug resistance Fulltext Access 7 Pages 2005
Design and synthesis of an optimized positional scanning library of peptoids: identification of novel multidrug resistance reversal agents Fulltext Access 7 Pages 2005
2,4,6-Trisubstituted pyrimidine derivatives as pregnancy interceptive agents Fulltext Access 7 Pages 2005
Parallel solid-phase synthesis and characterization of new sulfonamide and carboxamide proline derivatives as potential CNS agents Fulltext Access 7 Pages 2005
QSAR by LFER model of cytotoxicity data of anti-HIV 5-phenyl-1-phenylamino-1H-imidazole derivatives using principal component factor analysis and genetic function approximation Fulltext Access 7 Pages 2005
(R)-Goniothalamin: total syntheses and cytotoxic activity against cancer cell lines Fulltext Access 7 Pages 2005
Design, synthesis, and anti-tumor activity of (2-O-alkyloxime-3-phenyl)-propionyl-1-O-acetylbritannilactone esters Fulltext Access 7 Pages 2005
Isolation of brominated quinones showing chemiluminescence activity from luminous acorn worm, Ptychodera flava Fulltext Access 7 Pages 2005
Synthesis and biological evaluation of N-{4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl}-l-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway Fulltext Access 7 Pages 2005
Synthesis and antifungal activity of 2/3-arylthio- and 2,3-bis(arylthio)-5-hydroxy-/5-methoxy-1,4-naphthoquinones Fulltext Access 7 Pages 2005
Cationic TAT peptide transduction domain enters cells by macropinocytosis Fulltext Access 7 Pages 2005
Role of C-terminal regions of the C-terminal fragment of Clostridium perfringens enterotoxin in its interaction with claudin-4 Fulltext Access 7 Pages 2005
Evaluation of rapidly disintegrating tablets manufactured by phase transition of sugar alcohols Fulltext Access 7 Pages 2005
Oligonucleotide-protamine-albumin nanoparticles: Protamine sulfate causes drastic size reduction Fulltext Access 7 Pages 2005
Characteristics of nitrogen release from synthetic zeolite Na-P1 occluding NH4NO3 Fulltext Access 7 Pages 2005
A facile technique to prepare biodegradable coaxial electrospun nanofibers for controlled release of bioactive agents Fulltext Access 7 Pages 2005
Inhibition of metastatic tumor growth by targeted delivery of antioxidant enzymes Fulltext Access 7 Pages 2005
Synthesis, in vitro cytotoxic and antiviral activity of cis-[Pt(R(-) and S(+)-2-α-hydroxybenzylbenzimidazole)2Cl2] complexes Fulltext Access 7 Pages 2005
NO-donors, part 9 [1]: diazeniumdiolates inhibit human platelet aggregation and induce a transient vasodilatation of porcine pulmonary arteries in accordance with the NO-releasing rates Fulltext Access 7 Pages 2005
HIV protease inhibitors: synthesis and activity of N-aryl-Nâ²-hydroxyalkyl hydrazide pseudopeptides Fulltext Access 7 Pages 2005
An efficient preparation of polyanionic affinity agent and its evaluation for the measurement of glycated hemoglobin Fulltext Access 7 Pages 2005
Synthesis and antimicrobial activity of 4-phenyl/cyclohexyl-5-(1-phenoxyethyl)-3-[N-(2-thiazolyl)acetamido]thio-4H-1,2,4-triazole derivatives Fulltext Access 7 Pages 2005
Synthesis, physicochemical and in vitro pharmacological investigation of new platinum (II) complexes with some cycloalkanespiro-5â²-hydantoins Fulltext Access 7 Pages 2005
Synthesis and study of antibacterial and antifungal activities of novel 8-methyl-7,9-diaryl-1,2,4,8-tetraazaspiro[4.5]decan-3-thiones Fulltext Access 7 Pages 2005
The synthesis and antimicrobial activity of some new methyl N-arylthiocarbamates, dimethyl N-aryldithiocarbonimidates and 2-arylamino-2-imidazolines Fulltext Access 7 Pages 2005
Epoxide-containing side chains enhance antiproliferative activity of paullones Fulltext Access 7 Pages 2005
An unexpected amide bond cleavage: poly (ethylene glycol) transport forms of vancomycin. 2 Fulltext Access 7 Pages 2005
New thiophene analogues of kenpaullone: synthesis and biological evaluation in breast cancer cells Fulltext Access 7 Pages 2005
Synthesis and anticancer evaluation of certain 4-anilinofuro[2,3-b]quinoline and 4-anilinofuro[3,2-c]quinoline derivatives Fulltext Access 7 Pages 2005
Synthesis and antimalarial activity of E-2-quinolinylbenzocycloalcanones Fulltext Access 7 Pages 2005
Synthesis and antimicrobial study of novel heterocyclic compounds from hydroxybenzophenones Fulltext Access 7 Pages 2005
Synthesis and structure-activity relationships of mono- and dialkyl-substituted oxaliplatin derivatives Fulltext Access 7 Pages 2005
Proteins Markovian 3D-QSAR with spherically-truncated average electrostatic potentials Fulltext Access 7 Pages 2005
Amentoflavone and its derivatives as novel natural inhibitors of human Cathepsin B Fulltext Access 7 Pages 2005
Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory agents Fulltext Access 7 Pages 2005
Effects of peripheral substituents on diastereoselectivity of the fifth ligand-binding to chlorophylls, and nomenclature of the asymmetric axial coordination sites Fulltext Access 7 Pages 2005
Synthesis, antiproliferative, and vasorelaxing evaluations of coumarin α-methylene-γ-butyrolactones Fulltext Access 7 Pages 2005
Synthesis of 4-pyrido-6-aryl-2-substituted amino pyrimidines as a new class of antimalarial agents Fulltext Access 7 Pages 2005
Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand Fulltext Access 7 Pages 2005
Preparation and anti-inflammatory activities of diarylheptanoid and diarylheptylamine analogs Fulltext Access 7 Pages 2005
Synthesis and molecular recognition of carbohydrate-centered multivalent glycoclusters by a plant lectin RCA120 Fulltext Access 7 Pages 2005
Libertellenones A–D: Induction of cytotoxic diterpenoid biosynthesis by marine microbial competition Fulltext Access 7 Pages 2005
Improvement of ACE inhibitory activity of chitooligosaccharides (COS) by carboxyl modification Fulltext Access 7 Pages 2005
Chiral cruciferous phytoalexins: Preparation, absolute configuration, and biological activity Fulltext Access 7 Pages 2005
Optically active cantharidin analogues possessing selective inhibitory activity on Ser/Thr protein phosphatase 2B (calcineurin): Implications for the binding mode Fulltext Access 7 Pages 2005
Lead optimization of 7-benzyloxy 2-(4′-pyridylmethyl)thio isoflavone aromatase inhibitors Fulltext Access 7 Pages 2005
Tannins and related compounds induce nitric oxide synthase and cytokines gene expressions in Leishmania major-infected macrophage-like RAW 264.7 cells Fulltext Access 7 Pages 2005
Syntheses and biological activities of daunorubicin analogs with uncommon sugars Fulltext Access 7 Pages 2005
Synthesis, in vitro cellular uptake and photo-induced antiproliferative effects of lipophilic hypericin acid derivatives Fulltext Access 7 Pages 2005
Biological activities of retinoidal γ-hydroxybutenolides in cancer cell apoptosis and differentiation Fulltext Access 7 Pages 2005
Preliminary evaluation of the cytotoxicity of a series of tris-2-aminoethylamine (Tren) based hexadentate heterocyclic donor agents Fulltext Access 7 Pages 2005
Comparative QSAR study of phenol derivatives with the help of density functional theory Fulltext Access 7 Pages 2005
Verification of the turn at positions 22 and 23 of the β-amyloid fibrils with Italian mutation using solid-state NMR Fulltext Access 7 Pages 2005
The influence of aromatic residues in hydraphile spacer units: assay by ion selective electrode methods and in bacteria Fulltext Access 7 Pages 2005
Design, synthesis and cytotoxic effect of hydroxy- and 3-alkylaminopropoxy-9,10-anthraquinone derivatives Fulltext Access 7 Pages 2005
Synthesis and vasodilatory activity of new N-acylhydrazone derivatives, designed as LASSBio-294 analogues Fulltext Access 7 Pages 2005
Correlation of LUMO localization with the α-amylase inhibition constant in a Tendamistat-based series of linear and cyclic peptides Fulltext Access 7 Pages 2005
Synthesis of a novel potent cyclic peptide MC4-ligand by ring-closing metathesis Fulltext Access 7 Pages 2005
New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids Fulltext Access 7 Pages 2005
Studies on quinones. Part 39: Synthesis and leishmanicidal activity of acylchloroquinones and hydroquinones Fulltext Access 7 Pages 2005
Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells Fulltext Access 7 Pages 2005
Benzotropolone inhibitors of estradiol methylation: kinetics and in silico modeling studies Fulltext Access 7 Pages 2005
New sesquiterpenic phytotoxins establish unprecedented relationship between different groups of blackleg fungal isolates Fulltext Access 7 Pages 2005
Synthesis of novel DNA cross-linking antitumour agents based on polyazamacrocycles Fulltext Access 7 Pages 2005
Synthesis and evaluation of new ω-borono-α-amino acids as rat liver arginase inhibitors Fulltext Access 7 Pages 2005
Dihydropyrido[2,3-d]pyrimidines as a new class of antileishmanial agents Fulltext Access 7 Pages 2005
Novel heterocyclic family of phenyl naphthothiazole carboxamides derived from naphthalimides: synthesis, antitumor evaluation, and DNA photocleavage Fulltext Access 7 Pages 2005
Novel coumarin-3-(N-aryl)carboxamides arrest breast cancer cell growth by inhibiting ErbB-2 and ERK1 Fulltext Access 7 Pages 2005
New water soluble pyrroloquinoline derivatives as new potential anticancer agents Fulltext Access 7 Pages 2005
Synthesis and conformational study of 3,4-carbocyclic bridged indole melatonin and serotonin analogues Fulltext Access 7 Pages 2005
Synthesis of some new biologically active 1,3,4-oxadiazolyl nitroindoles and a modified Fischer indole synthesis of ethyl nitro indole-2-carboxylates Fulltext Access 7 Pages 2005
Lewis acid-promoted transformation of 2-alkoxypyridines into 2-aminopyridines and their antibacterial activity. Part 2: Remarkably facile C–N bond formation Fulltext Access 7 Pages 2005
Novel thiazonaphthalimides as efficient antitumor and DNA photocleaving agents: Effects of intercalation, side chains, and substituent groups Fulltext Access 7 Pages 2005
RO4383596, an orally active KDR, FGFR, and PDGFR inhibitor: Synthesis and biological evaluation Fulltext Access 7 Pages 2005
Novel synthesis and anti-inflammatory activities of 2,5-disubstituted-dioxacycloalkanes Fulltext Access 7 Pages 2005