Flow-through ultrasonic emulsification combined with static micromixing for aseptic production of microspheres by solvent extraction Fulltext Access 7 Pages 2005
QSAR for anti-RNA-virus activity, synthesis, and assay of anti-RSV carbonucleosides given a unified representation of spectral moments, quadratic, and topologic indices Fulltext Access 7 Pages 2005
Novel cyclopentane dicarboxamide sodium channel blockers as a potential treatment for chronic pain Fulltext Access 7 Pages 2005
QSAR studies on 1,2-dithiole-3-thiones: modeling of lipophilicity, quinone reductase specific activity, and production of growth hormone Fulltext Access 7 Pages 2005
Identification of a UDP-Gal: GlcNAc-R galactosyltransferase activity in Escherichia coli VW187 Fulltext Access 7 Pages 2005
In vitro adsorption of plasma proteins onto the surface (charges) modified-submicron emulsions for intravenous administration Fulltext Access 7 Pages 2005
Carbonic anhydrase inhibitors. Inhibition of the transmembrane isozyme XII with sulfonamides-a new target for the design of antitumor and antiglaucoma drugs? Fulltext Access 7 Pages 2005
Studies on synthesis and evaluation of quantitative structure-activity relationship of 5-[(3â²-chloro-4â²,4â²-disubstituted-2-oxoazetidinyl)(N-nitro)amino]-6-hydroxy-3-alkyl/aryl[1,3]azaphospholo[1,5-a]pyridin-1-yl-phosphorus dichlorides Fulltext Access 7 Pages 2005
Evaluation of extrusion/spheronisation, layering and compaction for the preparation of an oral, multi-particulate formulation of viable, hIL-10 producing Lactococcus lactis Fulltext Access 7 Pages 2005
Pharmacokinetic comparison of two recombinant human granulocyte colony-stimulating factor after subcutaneous administration in rabbits Fulltext Access 7 Pages 2005
Allosteric potentiators of the metabotropic glutamate receptor 2 (mGlu2). Part 3: Identification and biological activity of indanone containing mGlu2 receptor potentiators Fulltext Access 7 Pages 2005
Preparation of poly(N-isopropylacrylamide) copolymers and preliminary assessment of their acute and subacute toxicity in mice Fulltext Access 7 Pages 2005
Use of nonlinear mixed effect modeling for the intestinal absorption data: Application to ritonavir in the rat Fulltext Access 7 Pages 2005
Flow injection spectrophotometric determination of ofloxacin in pharmaceuticals and urine Fulltext Access 7 Pages 2005
Handling of computational in vitro/in vivo correlation problems by Microsoft Excel: IV. Generalized matrix analysis of linear compartment systems Fulltext Access 7 Pages 2005
Evaluation of in vitro and in vivo antitumor activity of BCNU-loaded PLGA wafer against 9L gliosarcoma Fulltext Access 7 Pages 2005
The evaluation of the local tolerance of vaginal formulations containing dapivirine using the Slug Mucosal Irritation test and the rabbit vaginal irritation test Fulltext Access 7 Pages 2005
Cryoconserved shielded and EGF receptor targeted DNA polyplexes: cellular mechanisms Fulltext Access 7 Pages 2005
Pharmacokinetics of an immediate release, a controlled release and a two pulse dosage form in dogs Fulltext Access 7 Pages 2005
Novel β-(imidazol-4-yl)-β-amino acids: solid-phase synthesis and study of their inhibitory activity against geranylgeranyl protein transferase type I Fulltext Access 7 Pages 2005
pH- and temperature-sensitive release behaviors from polyelectrolyte complex films composed of chitosan and PAOMA copolymer Fulltext Access 7 Pages 2005
Need for new vaccine formulations and potential of particulate antigen and DNA delivery systems Fulltext Access 7 Pages 2005
Starch/Carbopol® spray-dried mixtures as excipients for oral sustained drug delivery Fulltext Access 7 Pages 2005
5-Chloroindoloyl glycine amide inhibitors of glycogen phosphorylase: synthesis, in vitro, in vivo, and X-ray crystallographic characterization Fulltext Access 7 Pages 2005
QSAR study on the antibacterial activity of some sulfa drugs: building blockers of Mannich bases Fulltext Access 7 Pages 2005
Effects of positional and geometrical isomerism on the biological activity of some novel oxazolidinones Fulltext Access 7 Pages 2005
Difference in absorption of the two structurally similar flavonoid glycosides, hyperoside and isoquercitrin, in rats Fulltext Access 7 Pages 2005
Unified Markov thermodynamics based on stochastic forms to classify drugs considering molecular structure, partition system, and biological species: Fulltext Access 7 Pages 2005
QSAR study on pKa vis-Ã -vis physiological activity of sulfonamides: a dominating role of surface tension (inverse steric parameter) Fulltext Access 7 Pages 2005
Amino-substituted heterocycles as isosteres of trans-cinnamides: design and synthesis of heterocyclic biaryl sulfides as potent antagonists of LFA-1/ICAM-1 binding Fulltext Access 7 Pages 2005
Estrogen receptor ligands. Part 9: Dihydrobenzoxathiin SERAMs with alkyl substituted pyrrolidine side chains and linkers Fulltext Access 7 Pages 2005
Estrogen receptor ligands. Part 10: Chromanes: old scaffolds for new SERAMs Fulltext Access 7 Pages 2005
Interaction of 31 β-lactam antibiotics with the H+/peptide symporter PEPT2: analysis of affinity constants and comparison with PEPT1 Fulltext Access 8 Pages 2005
Targeting of sterically stabilised pH-sensitive liposomes to human T-leukaemia cells Fulltext Access 8 Pages 2005
Solid-state characterization and dissolution properties of Naproxen-Arginine-Hydroxypropyl-β-cyclodextrin ternary system Fulltext Access 8 Pages 2005
Study of the physicochemical properties and stability of solid dispersions of loperamide and PEG6000 prepared by spray drying Fulltext Access 8 Pages 2005
QSAR studies on benzene sulfonamide carbonic anhydrase inhibitors: need of hydrophobic parameter for topological modeling of binding constants of sulfonamides to human CA-II Fulltext Access 8 Pages 2005
Effects of gamma-irradiation on trehalose-hydroxyethylcellulose microspheres loaded with vancomycin Fulltext Access 8 Pages 2005
Physical solid-state properties and dissolution of sustained-release matrices of polyvinylacetate Fulltext Access 8 Pages 2005
Influence of hydroxyethylcellulose on the drug release properties of theophylline pellets coated with Eudragit® RS 30 D Fulltext Access 8 Pages 2005
Liposomal incorporation of Artemisia arborescens L. essential oil and in vitro antiviral activity Fulltext Access 8 Pages 2005
Characterization of cellulosic hot-melt extruded films containing lidocaine Fulltext Access 8 Pages 2005
The impact of antimalarial drug resistance mutations on parasite fitness, and its implications for the evolution of resistance Fulltext Access 8 Pages 2005
Fibroblast activation protein-α and dipeptidyl peptidase IV (CD26): Cell-surface proteases that activate cell signaling and are potential targets for cancer therapy Fulltext Access 8 Pages 2005
Novel pyrazinone mono-amides as potent and reversible caspase-3 inhibitors Fulltext Access 8 Pages 2005
QSAR studies on structurally similar 2-(4-methanesulfonylphenyl)pyran-4-ones as selective COX-2 inhibitors: a Hansch approach Fulltext Access 8 Pages 2005
Selective interactions of perylene derivatives having different side chains with inter- and intramolecular G-quadruplex DNA structures. A correlation with telomerase inhibition Fulltext Access 8 Pages 2005
Literature highlights: Recent research in infectious disease drug resistance Fulltext Access 8 Pages 2005
Literature highlights: recent research in infectious disease drug resistance Fulltext Access 8 Pages 2005
1-N-Substituted Thiocarbamoyl-3-Phenyl-2-Pyrazolines: Synthesis and In Vitro Antiamoebic Activities Fulltext Access 8 Pages 2005
Synthesis and cytotoxic activity of 2-acyl-1H-indole-4,7-diones on human cancer cell lines Fulltext Access 8 Pages 2005
The interaction between resistance modifiers such as pyrido[3,2-g]quinoline, aza-oxafluorene and pregnane derivatives with DNA, plasmid DNA and tRNA Fulltext Access 8 Pages 2005
Synthesis of novel amino and acetyl amino-4-methylcoumarins and evaluation of their antioxidant activity Fulltext Access 8 Pages 2005
Molecular basis of the low activity of antitumor anthracenediones, mitoxantrone and ametantrone, in oxygen radical generation catalyzed by NADH dehydrogenase. Enzymatic and molecular modelling studies Fulltext Access 8 Pages 2005
Novel Cu(II) quinoxaline N1,N4-dioxide complexes as selective hypoxic cytotoxins Fulltext Access 8 Pages 2005
Benzoyl and/or benzyl substituted 1,2,3-triazoles as potassium channel activators. VIII Fulltext Access 8 Pages 2005
Preparation of celecoxib-dimethyl-β-cyclodextrin inclusion complex: characterization and in vitro permeation study Fulltext Access 8 Pages 2005
α-Aminoalkylphosphonates as a tool in experimental optimisation of P1 side chain shape of potential inhibitors in S1 pocket of leucine- and neutral aminopeptidases Fulltext Access 8 Pages 2005
Synthesis and potent antibacterial activity against MRSA of some novel 1,2-disubstituted-1H-benzimidazole-N-alkylated-5-carboxamidines Fulltext Access 8 Pages 2005
Synthesis and properties of isocannabinoid and cholesterol derivatized rhamnosurfactants: application to liposomal targeting of keratinocytes and skin Fulltext Access 8 Pages 2005
Synthesis, antibacterial, antifungal activity and interaction of CT-DNA with a new benzimidazole derived Cu(II) complex Fulltext Access 8 Pages 2005
Synthesis and antiproliferative activity of 2,6-Dibenzylamino-3,5-dicyanopyridines on human cancer cell lines Fulltext Access 8 Pages 2005
Synthesis and antimicrobial activity of some novel derivatives of benzofuran: part 1. Synthesis and antimicrobial activity of (benzofuran-2-yl)(3-phenyl-3-methylcyclobutyl) ketoxime derivatives Fulltext Access 8 Pages 2005
Synthesis, antimicrobial activity and molecular modeling of cobalt and nickel complexes containing the bulky ligand: bis[N-(2,6-diisopropylphenyl)imino] acenaphthene Fulltext Access 8 Pages 2005
Synthesis of 2,6-diphenylpyrazine derivatives and their DNA binding and cytotoxic properties Fulltext Access 8 Pages 2005
à propos d'une expérience d'organisation de dispensation journalière individuelle nominative (DJIN) Fulltext Access 8 Pages 2005
Validation des conditions de conservation des produits de santé thermosensibles : obligations et modalités pratiques dans une PUI Fulltext Access 8 Pages 2005
Erreurs liées au conditionnement des médicaments : quelles mesures prendre pour les réduire ? Fulltext Access 8 Pages 2005
Poly(ethylene-co-methyl acrylate) membranes as rate-controlling barriers for drug delivery systems: characterization, mechanical properties and permeability Fulltext Access 8 Pages 2005
Quantitative evaluation of polymer concentration profile during swelling of hydrophilic matrix tablets using 1H NMR and MRI methods Fulltext Access 8 Pages 2005
The influence of gellan gum on the transfer of fluorescein dextran across rat nasal epithelium in vivo Fulltext Access 8 Pages 2005
Albumin-protamine-oligonucleotide-nanoparticles as a new antisense delivery system. Part 2: cellular uptake and effect Fulltext Access 8 Pages 2005
Design of a phytosphingosine-containing, positively-charged nanoemulsion as a colloidal carrier system for dermal application of ceramides Fulltext Access 8 Pages 2005
Effect of SBE7-β-cyclodextrin complexation on carbamazepine release from sustained release beads Fulltext Access 8 Pages 2005
Carboxymethyl high amylose starch (CM-HAS) as excipient for Escherichia coli oral formulations Fulltext Access 8 Pages 2005
Cyclodextrin complexes of valdecoxib: properties and anti-inflammatory activity in rat Fulltext Access 8 Pages 2005
In vitro availability of kaempferol glycosides from cream formulations of methanolic extract of the leaves of Melilotus elegans Fulltext Access 8 Pages 2005
Cationic lipid-protamine-DNA (LPD) complexes for delivery of antisense c-myc oligonucleotides Fulltext Access 8 Pages 2005
Isothermal titration calorimetry method for determination of cyclodextrin complexation thermodynamics between artemisinin and naproxen under varying environmental conditions Fulltext Access 8 Pages 2005
Targeting delivery of oligonucleotide and plasmid DNA to hepatocyte via galactosylated chitosan vector Fulltext Access 8 Pages 2005
Differences in product information of biopharmaceuticals in the EU and the USA: implications for product development Fulltext Access 8 Pages 2005
Effects of cryoprotectants on the viability and activity of freeze dried recombinant yeasts as novel oral drug delivery systems assessed by an artificial digestive system Fulltext Access 8 Pages 2005
Development of an enteric-coated, layered multi-particulate formulation for ileal delivery of viable recombinant Lactococcus lactis Fulltext Access 8 Pages 2005
Delivery of a lentiviral vector in a Pluronic F127 gel to cells of the central nervous system Fulltext Access 8 Pages 2005
The use of thiolated polymers as carrier matrix in oral peptide delivery-Proof of concept Fulltext Access 8 Pages 2005
Effect of enzymatic degradation on the release kinetics of model drug from Pluronic F127/poly(lactic acid) nano-particles Fulltext Access 8 Pages 2005
Local and systemic drug competition in drug-eluting stent tissue deposition properties Fulltext Access 8 Pages 2005