Sex-specific differences in corticosterone secretion, behavioral phenotypes and expression of TrkB.T1 and TrkB.FL receptor isoforms: Impact of systemic TrkB inhibition and combinatory stress exposure in adolescence Fulltext Access 42 Pages 2018
3-(4-Chlorophenylselanyl)-1-methyl-1H-indole, a new selenium compound elicits an antinociceptive and anti-inflammatory effect in mice Fulltext Access 42 Pages 2018
Nicotinamide prevents sweet beverage-induced hepatic steatosis in rats by regulating the G6PD, NADPH/NADP+ and GSH/GSSG ratios and reducing oxidative and inflammatory stress Fulltext Access 42 Pages 2018
Cardiovascular pressor effects of orexins in the dorsomedial hypothalamus Fulltext Access 42 Pages 2018
Neuroprotective effect of an Nrf2-ARE activator identified from a chemical library on dopaminergic neurons Fulltext Access 42 Pages 2018
The polyherbal drug GGEx18 from Laminaria japonica, Rheum palmatum, and Ephedra sinica inhibits hepatic steatosis and fibroinflammtion in high-fat diet-induced obese mice Fulltext Access 42 Pages 2018
Anti-allergy and anti-tussive activity of Clitoria ternatea L. in experimental animals Fulltext Access 42 Pages 2018
Effects of water extract from epimedium on neuropeptide signaling in an ovariectomized osteoporosis rat model Fulltext Access 42 Pages 2018
Gastro-protective effect of edible plant Artemisia argyi in ethanol-induced rats via normalizing inflammatory responses and oxidative stress Fulltext Access 42 Pages 2018
Pyrrolidine dithiocarbamate inhibits mouse acute kidney injury induced by diclofenac by targeting oxidative damage, cytokines and NF-κB activity Fulltext Access 42 Pages 2018
Oral hydroxysafflor yellow A reduces obesity in mice by modulating the gut microbiota and serum metabolism Fulltext Access 42 Pages 2018
The immature electrophysiological phenotype of iPSC-CMs still hampers in vitro drug screening: Special focus on IK1 Fulltext Access 42 Pages 2018
Histone deacetylases (HDACs) as therapeutic target for depressive disorders Fulltext Access 42 Pages 2018
microRNA and mRNA profiles in ventral tegmental area relevant to stress-induced depression and resilience Fulltext Access 42 Pages 2018
Oral N-acetylcysteine in the treatment of obsessive-compulsive disorder: A systematic review of the clinical evidence Fulltext Access 42 Pages 2018
PIKfyve inhibitor cytotoxicity requires AKT suppression and excessive cytoplasmic vacuolation Fulltext Access 42 Pages 2018
Binge ethanol exposure induces endoplasmic reticulum stress in the brain of adult mice Fulltext Access 42 Pages 2018
H2S protects lipopolysaccharide-induced inflammation by blocking NFκB transactivation in endothelial cells Fulltext Access 42 Pages 2018
Ginsenoside-Rp3 inhibits platelet activation and thrombus formation by regulating MAPK and cyclic nucleotide signaling Fulltext Access 42 Pages 2018
Chemical characterisation and toxicity assessment in vitro and in vivo of the hydroethanolic extract of Terminalia argentea Mart. leaves Fulltext Access 42 Pages 2018
Zaprinast diminished pain and enhanced opioid analgesia in a rat neuropathic pain model Fulltext Access 42 Pages 2018
A pentacyclic triterpene derivative possessing polyhydroxyl ring A suppresses growth of HeLa cells by reactive oxygen species-dependent NF-κB pathway Fulltext Access 42 Pages 2018
Berberine modulates ASK1 signaling mediated through TLR4/TRAF2 via upregulation of miR-23a Fulltext Access 42 Pages 2018
Potential role of α-lipoic acid and Ginkgo biloba against silver nanoparticles-induced neuronal apoptosis and blood-brain barrier impairments in rats Fulltext Access 42 Pages 2018
Intracerebroventricular streptozotocin impairs adult neurogenesis and cognitive functions via regulating neuroinflammation and insulin signaling in adult rats Fulltext Access 42 Pages 2018
Evaluation of Spironolactone Solid Dispersions Prepared by Co-Spray Drying With Soluplus® and Polyvinylpyrrolidone and Influence of Tableting on Drug Release Fulltext Access 42 Pages 2018
Fabrication and Use of Poly(d,l-lactide-co-glycolide)-Based Formulations Designed for Modified Release of 5-Fluorouracil Fulltext Access 42 Pages 2018
Pharmacokinetic and pharmacodynamic evaluation of 5-methoxy-2-aminoindane (MEAI): A new binge-mitigating agent Fulltext Access 43 Pages 2018
microRNA-96 acts as a tumor suppressor gene in human osteosarcoma via target regulation of EZRIN Fulltext Access 43 Pages 2018
Heme oxygenase-1 protects liver against ischemia/reperfusion injury via phosphoglycerate mutase family member 5-mediated mitochondrial quality control Fulltext Access 43 Pages 2018
Oncostatin M upregulates HIF-1α in breast tumor associated macrophages independent of intracellular oxygen concentration Fulltext Access 43 Pages 2018
Human-based systems: Mechanistic NASH modelling just around the corner? Fulltext Access 43 Pages 2018
Identification of certain Panax species to be potential substitutes for Panax notoginseng in hemostatic treatments Fulltext Access 43 Pages 2018
Novel 1,4-benzothazines obliterate COX-2 mediated JAK-2/STAT-3 signals with potential regulation of oxidative and metabolic stress during colorectal cancer Fulltext Access 43 Pages 2018
trans-Resveratrol ameliorates anxiety-like behaviors and fear memory deficits in a rat model of post-traumatic stress disorder Fulltext Access 43 Pages 2018
Dendritic spine anomalies and PTEN alterations in a mouse model of VPA-induced autism spectrum disorder Fulltext Access 43 Pages 2018
Protective effects of the GLP-1 mimetic exendin-4 in Parkinson's disease Fulltext Access 43 Pages 2018
Group I metabotropic glutamate receptors generate two types of intrinsic membrane oscillations in hippocampal oriens/alveus interneurons Fulltext Access 43 Pages 2018
Ionotropic and metabotropic glutamate receptors regulate protein translation in co-cultured nucleus accumbens and prefrontal cortex neurons Fulltext Access 43 Pages 2018
Long-acting β2-adrenoreceptor agonists suppress type 1 interferon expression in human plasmacytoid dendritic cells via epigenetic regulation Fulltext Access 43 Pages 2018
Rifampin Stability and Solution Concentration Enhancement Through Amorphous Solid Dispersion in Cellulose Ï-Carboxyalkanoate Matrices Fulltext Access 43 Pages 2018
Constitutive activity of the metabotropic glutamate receptor 2 explored with a whole-cell label-free biosensor Fulltext Access 43 Pages 2018
Individual serum bile acid profiling in rats aids in human risk assessment of drug-induced liver injury due to BSEP inhibition Fulltext Access 43 Pages 2018
Toxicodynamics of Lead, Cadmium, Mercury and Arsenic- induced kidney toxicity and treatment strategy: A mini review Fulltext Access 43 Pages 2018
EGFR tyrosine kinase inhibition decreases cardiac remodeling and SERCA2a/NCX1 depletion in streptozotocin induced cardiomyopathy in C57/BL6 mice Fulltext Access 43 Pages 2018
Agmatine potentiates neuroprotective effects of subthreshold concentrations of ketamine via mTOR/S6 kinase signaling pathway Fulltext Access 43 Pages 2018
Montelukast attenuates rotenone-induced microglial activation/p38 MAPK expression in rats: Possible role of its antioxidant, anti-inflammatory and antiapoptotic effects Fulltext Access 43 Pages 2018
Role of Toll-like receptor 4/oxidant-coupled activation in regulating the biosynthesis of omega-3 polyunsaturated fatty acid derivative resolvin D1 in primary murine peritoneal macrophage Fulltext Access 43 Pages 2018
In vitro effects of Crotalus atrox snake venom on chick and mouse neuromuscular preparations Fulltext Access 43 Pages 2018
The 5-HT3 receptor antagonist ondansetron potentiates the effects of the acetylcholinesterase inhibitor donepezil on neuronal network oscillations in the rat dorsal hippocampus Fulltext Access 43 Pages 2018
Effects of acute Î9-tetrahydrocannabinol on next-day extinction recall is mediated by post-extinction resting-state brain dynamics Fulltext Access 43 Pages 2018
Activation of α7 nicotinic acetylcholine receptor alleviates Aβ1-42-induced neurotoxicity via downregulation of p38 and JNK MAPK signaling pathways Fulltext Access 43 Pages 2018
The organophosphate pesticide methamidophos opens the blood-testis barrier and covalently binds to ZO-2 in mice Fulltext Access 43 Pages 2018
Inhibition of p21-activated kinase 1 attenuates the cardinal features of asthma through suppressing the lymph node homing of dendritic cells Fulltext Access 43 Pages 2018
Identification of Compound-B, a novel anti-dengue virus agent targeting the non-structural protein 4A Fulltext Access 43 Pages 2018
Investigation of the therapy targets of Yi-Qi-Yang-Yin-Hua-Tan-Qu-Yu recipe on type 2 diabetes by serum proteome labeled with iTRAQ Fulltext Access 43 Pages 2018
Activity profile of the cisplatin analogue PN149 in different tumor cell lines Fulltext Access 43 Pages 2018
Quantitative characterization of UDP-glucuronosyltransferase 2B17 in human liver and intestine and its role in testosterone first-pass metabolism Fulltext Access 43 Pages 2018
Activation of aryl hydrocarbon receptor regulates the LPS/IFNγ-induced inflammatory response by inducing ubiquitin-proteosomal and lysosomal degradation of RelA/p65 Fulltext Access 43 Pages 2018
Effects of cytochrome P450 single nucleotide polymorphisms on methadone metabolism and pharmacodynamics Fulltext Access 43 Pages 2018
N-propyl-2,2-diphenyl-2-hydroxyacetamide, a novel α-hydroxyamide with anticonvulsant, anxiolytic and antidepressant-like effects that inhibits voltage-gated sodium channels Fulltext Access 43 Pages 2018
Salvianolic acid B improves airway hyperresponsiveness by inhibiting MUC5AC overproduction associated with Erk1/2/P38 signaling Fulltext Access 43 Pages 2018
Deoxyelephantopin ameliorates lipopolysaccharides (LPS)-induced memory impairments in rats: Evidence for its anti-neuroinflammatory properties Fulltext Access 43 Pages 2018
Treatments for diabetes mellitus type II: New perspectives regarding the possible role of calcium and cAMP interaction Fulltext Access 43 Pages 2018
Dopaminergic and serotonergic mechanisms in the modulation of pain: In vivo studies in human brain Fulltext Access 43 Pages 2018
Conflicting roles of 20-HETE in hypertension and renal end organ damage Fulltext Access 43 Pages 2018
Ozone protects the rat lung from ischemia-reperfusion injury by attenuating NLRP3-mediated inflammation, enhancing Nrf2 antioxidant activity and inhibiting apoptosis Fulltext Access 43 Pages 2018
Ketamine and ketamine metabolites as novel estrogen receptor ligands: Induction of cytochrome P450 and AMPA glutamate receptor gene expression Fulltext Access 43 Pages 2018
The genus Datura L. (Solanaceae) in Mexico and Spain - Ethnobotanical perspective at the interface of medical and illicit uses Fulltext Access 43 Pages 2018
Aloysia citrodora Paláu (Lemon verbena): A review of phytochemistry and pharmacology Fulltext Access 43 Pages 2018
IL-1β reduces GluA1 phosphorylation and its surface expression during memory reconsolidation and α-melanocyte-stimulating hormone can modulate these effects Fulltext Access 43 Pages 2018
Homer2 within the central nucleus of the amygdala modulates withdrawal-induced anxiety in a mouse model of binge-drinking Fulltext Access 43 Pages 2018
The impact of regional locality on chemical composition, anti-oxidant and biological activities of Thymelaea hirsuta L. extracts Fulltext Access 43 Pages 2018
Leaves of Spondias mombin L. a traditional anxiolytic and antidepressant: Pharmacological evaluation on zebrafish (Danio rerio) Fulltext Access 43 Pages 2018
The effects of Nrf2 knockout on regulation of benzene-induced mouse hematotoxicity Fulltext Access 44 Pages 2018
Zhen-wu-tang ameliorates adenine-induced chronic renal failure in rats: regulation of the canonical Wnt4/beta-catenin signaling in the kidneys Fulltext Access 44 Pages 2018
Altered microRNA regulation of short chain fatty acid receptors in the hypertensive kidney is normalized with hydrogen sulfide supplementation Fulltext Access 44 Pages 2018
Effects of d-amphetamine on risk choice in rats depend on the manner in which the expected reward value is varied Fulltext Access 44 Pages 2018
Thyroid hormones affect nitrergic innervation function in rat mesenteric artery: Role of the PI3K/AKT pathway Fulltext Access 44 Pages 2018
Simvastatin accelerates hematoma resolution after intracerebral hemorrhage in a PPARγ-dependent manner Fulltext Access 44 Pages 2018
microRNA-136 inhibits proliferation and promotes apoptosis and radiosensitivity of cervical carcinoma through the NF-κB pathway by targeting E2F1 Fulltext Access 44 Pages 2018
Evaluation of behavioral parameters, hematological markers, liver and kidney functions in rodents exposed to Deepwater Horizon crude oil and Corexit Fulltext Access 44 Pages 2018
Irbesartan attenuates advanced glycation end products-mediated damage in diabetes-associated osteoporosis through the AGEs/RAGE pathway Fulltext Access 44 Pages 2018
Nicotine alleviates chronic stress-induced anxiety and depressive-like behavior and hippocampal neuropathology via regulating autophagy signaling Fulltext Access 44 Pages 2018
Mechanism of N6-methyladenosine modification and its emerging role in cancer Fulltext Access 44 Pages 2018
The role of the vasopressin V1A receptor in oxytocin modulation of methamphetamine primed reinstatement Fulltext Access 44 Pages 2018
Activation of NLRX1-mediated autophagy accelerates the ototoxic potential of cisplatin in auditory cells Fulltext Access 44 Pages 2018
Orally administered berberine ameliorates bleomycin-induced pulmonary fibrosis in mice through promoting activation of PPAR-γ and subsequent expression of HGF in colons Fulltext Access 44 Pages 2018
Gene expression profiling of human bronchial epithelial cells exposed to fine particulate matter (PM2.5) from biomass combustion Fulltext Access 44 Pages 2018
Yangonin protects against cholestasis and hepatotoxity via activation of farnesoid X receptor in vivo and in vitro Fulltext Access 44 Pages 2018
Toxicological study of a new doxorubicin-loaded pH-sensitive liposome: A preclinical approach Fulltext Access 44 Pages 2018
Clitoria ternatea L. root extract ameliorated the cognitive and hippocampal long-term potentiation deficits induced by chronic cerebral hypoperfusion in the rat Fulltext Access 44 Pages 2018
Prenatal ethanol induces an anxiety phenotype and alters expression of dynorphin & nociceptin/orphanin FQ genes Fulltext Access 44 Pages 2018
Interrogation of ethnomedicinal plants for synthetic lethality effects in combination with deficiency in the DNA repair endonuclease RAD1 using a yeast cell-based assay Fulltext Access 44 Pages 2018