کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
19979 43151 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Maximum-biomass prediction of homofermentative Lactobacillus
ترجمه فارسی عنوان
پیش بینی حداکثر زیست توده لاکتوباسیلوس هموفرنتوتیک
کلمات کلیدی
لاکتوباسیلوس Homofermentative؛ لاکتات؛ آنیون اسید؛ حداکثر زیست توده؛ معادله پیش بینی
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
چکیده انگلیسی

Fed-batch and pH-controlled cultures have been widely used for industrial production of probiotics. The aim of this study was to systematically investigate the relationship between the maximum biomass of different homofermentative Lactobacillus and lactate accumulation, and to develop a prediction equation for the maximum biomass concentration in such cultures. The accumulation of the end products and the depletion of nutrients by various strains were evaluated. In addition, the minimum inhibitory concentrations (MICs) of acid anions for various strains at pH 7.0 were examined. The lactate concentration at the point of complete inhibition was not significantly different from the MIC of lactate for all of the strains, although the inhibition mechanism of lactate and acetate on Lactobacillus rhamnosus was different from the other strains which were inhibited by the osmotic pressure caused by acid anions at pH 7.0. When the lactate concentration accumulated to the MIC, the strains stopped growing. The maximum biomass was closely related to the biomass yield per unit of lactate produced (YX/P) and the MIC (C) of lactate for different homofermentative Lactobacillus. Based on the experimental data obtained using different homofermentative Lactobacillus, a prediction equation was established as follows: Xmax − X0 = (0.59 ± 0.02)·YX/P·C.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Bioscience and Bioengineering - Volume 122, Issue 1, July 2016, Pages 52–57
نویسندگان
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