Keywords: کامپتوتسین ; Sophoridine; Topoisomerase I; Camptothecin; Schiff base; Antitumor activity;
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Keywords: کامپتوتسین ; 2,5-DXP; 2,5-diketopiperazine; ACC; adenoid cystic carcinomas; BBR; berberine; BET; bromodomain and extraterminal; CA; chebulagic acid; CPT; camptothecin; EMT; epithelial-mesenchymal transition; GSK3; glycogen synthase kinase 3-; HCC; hepatocellular carci
Keywords: کامپتوتسین ; AC; anthroposophic constitution; AM; anthroposophic medicine; AR; autonomic regulation; ARQ; questionnaire on autonomic regulation; BMI; body mass index; CFSE; carboxyfluorescein diacetate succinimidyl ester; CPT; camptothecin; CsA; cyclosporine A; KC; co
Keywords: کامپتوتسین ; Camptothecin; Heterolipid E1E; Self-microemulsifying drug delivery system; Solubility enhancement; Anti-tumor activity; Molecular simulation;
Keywords: کامپتوتسین ; Magnesium ferrite; Magnetic nanoparticle; Camptothecin; β-Cyclodextrin; Poly(vinyl alcohol);
Keywords: کامپتوتسین ; Solid lipid nanoparticles; Oral administration; Reduction-response; Lipid-drug conjugate; Camptothecin;
Keywords: کامپتوتسین ; 56MESS; (1S2S-diaminocyclohexane)platinum(II)] dichloride; AIBN; 2,2â²-azobisisobutyronitrile; Apt; aptamer; AUC; area under curve; BBR3464; (trans,trans,trans)-bis-mu-(hexane-16-diamine)-mu-[diammineplatinum(II)]bis[diammine(chloro)platinum(II)] tetrani
Keywords: کامپتوتسین ; Drug conjugate; Capecitabine; Camptothecin; Drug delivery; Chemotherapy;
Keywords: کامپتوتسین ; SCLC; small cell lung cancer; CAM; chorioallantoic membrane; CI; combination index; STR; short tandem repeat; RPMI; Roswell Park Memorial Institute; EDTA; ethylene diamine tetraacetic acid; HEPES; 4-(2-hydroxyethyl)-1-piperazineethanesulfonic acid; SPF; s
Keywords: کامپتوتسین ; GFN; graphene family nanomaterials; GO; graphene oxide; rGO; reduced graphene oxide; TLR4; toll-like receptor 4; PEG; polyethylene glycol; CPT; camptothecin; SN-38; 7-ethyl-10-hydroxy camptothecin; PNIPAM; poly N-isopropyl acrylamide; NGO; nano graphene o
Keywords: کامپتوتسین ; Nanomedicine; Smart chemistry; Nanocarrier; Drug delivery; AAP; arylazopyrazoles; BIC; block ionomeric complex; BSA-c-PheoA; bovine serum albumin-cis-aconityl pheophorbide-A; CA; cis-aconitic anhydride; CPP; cell-penetrating peptides; CPT; camptothecin; C
Keywords: کامپتوتسین ; PEG; Polyethylene glycol; PEG-b-PS; Polyethylene glycol-block-polystyrene; PEG-b-PCL; Polyethylene glycol-block-polycaprolactone; PEG-b-PLA; Polyethylene glycol-block-poly(lactic acid); PLGA; Poly(lactic-co-glycolic acid); HA-g-PLGA; Poly(lactic acidco-gl
Keywords: کامپتوتسین ; Cancer; Target therapy; Prodrug; MDR; Multidrug resistance; ROS; Reactive oxygen species; GSH; Glutathione; ADCs; Antibody-drug conjugates; ADEPT; Antibody-directed enzyme prodrug therapy; GDEPT; Gene-directed enzyme prodrug therapy; HIF; Hypoxia-inducibl
Keywords: کامپتوتسین ; hydroxycamptothecin; folate-decorated human serum albumin; targeted delivery system; tissue distribution; CPT; camptothecin; DMEM; Dulbecco's modified eagle medium; FA; folate; FA-HSA-nHCPT-NPs; folate-decorated human serum albumin loaded with nano-hydrox
Keywords: کامپتوتسین ; Drug delivery; Controlled release; Nanomedicines; Mesoporous silica; Camptothecin; Redox-responsive;
Keywords: کامپتوتسین ; Self-assembly; Polymersome; Camptothecin; PEG; Caprolactone
Keywords: کامپتوتسین ; Camptothecin; Solid lipid nanoparticles; Reticuloendothelial system blocking; Tumor targeting; Pharmacokinetics; Antitumor activity
Keywords: کامپتوتسین ; Camptothecin (PubChem CID: 24360); Gantrez AN (PubChem CID: 62708); 2-Hydroxypropyl-β-cyclodextrin (PubChem CID: 44134771); β-Cyclodextrin (PubChem CID: 444041); Methyl-β-cyclodextrin (PubChem CID: 51051622); Camptothecin; Nanoparticles; Cyclodextrins;
Keywords: کامپتوتسین ; Sesamum indicum L.; Water-soluble fraction; Neuroprotective; SH-SY5Y cell; Anti-apoptosis; Akt; protein kinase B; Bax; Bcl-2 associated X protein; Bcl-2; B-cell lymphoma 2; BrdU; 5-bromo-2-desoxyuridine; CPT; camptothecin; FA; ferulic acid; GS-wsf; gold s
Keywords: کامپتوتسین ; ACPP; activated cell-penetrating peptide; AFM; atomic force microscopy; AN; angiopeptin; ANP; NP modified with ACPP peptide; APE-1; apurinic endonuclease-1; AU; gold; AUC; area under the curve; AUNP; gold nanoparticles; AUNS; gold nanoshells; BAT; brain a
Keywords: کامپتوتسین ; ADH; adipic acid dihydrazide; AUNPs; gold nanoparticles; BA; butyric acid; CDDP; cisplatin; CHI; chitosane; CNTs; carbon nanotubes; CPT; camptothecin; CSCs; cancer stem cells; DiPhPE; diphytanoyl-sn-glycero-3-glycerophosphatidyl ethanolamine; DL; drug loa
Keywords: کامپتوتسین ; 3D; three-dimensional; ACA; alkylcyanoacrylates; AETMAC; 2-acryloxyethyltrimethylammonium chloride; ATRP; atom transfer radical polymerization; AuNPs; gold nanoparticles; bFGF; basic fibroblast growth factor; BM-MSCs; bone marrow-derived mesenchymal stem
Keywords: کامپتوتسین ; Caprolactone (PubChem CID: 10401); Ethylene glycol (PubChem CID: 174); Camptothecin (PubChem CID: 24360); Folic acid (PubChem CID: 6037)Nanoparticles; Matrix metalloproteases; Camptothecin; Targeting; Polycaprolactone
Keywords: کامپتوتسین ; CIJ; confined impinging jet; CPT; camptothecin; dLN; draining lymph node; ECM; extracellular matrix; EPR; enhanced permeability and retention; FNP; flash nanoprecipitation; i.d.; intradermal; i.v.; intravenous; LbL; layer-by-layer; LN; lymph node; MIVM; m
Keywords: کامپتوتسین ; Camptothecin; C-20 position; Cytotoxic activity; Spin-labeled;
Keywords: کامپتوتسین ; BMA; n-butyl methacrylate; BSA; bovine serum albumin; CB; carboxybetaine; CD; cyclodextrin; CPT; camptothecin; DMA; 2-(dimethylamino)ethyl methacrylate; DOX; doxorubicin; DPA; 2-(diisopropylamino)ethyl methacrylate; DSPE; 1,2-distearoyl-sn-glycero-3-phosp
Keywords: کامپتوتسین ; Surface coating; Nanoparticles; Camptothecin; Hyperbranched polyglycerol; Polylactic acid;
Keywords: کامپتوتسین ; Camptothecin; Mannitol; Nanoparticles; High pressure homogenization; Central composite design; Antitumor;
Keywords: کامپتوتسین ; Dioxinocamptothecin; Antitumor; Camptothecin; Oral; Permeability; TransportCPT, 20-(S)-camptothecin; CDiox, 9, 10-[1,3]-dioxinocamptothecin; SAz, sodium azide; Pgp, P-glycoprotein 1; Annexin V-FITC/PI, annexin V–fluorescein isothiocyanate/propidium iodide
Keywords: کامپتوتسین ; Anti-cancer; Polymeric micelles; Sustained delivery; Doxorubicin; Paclitaxel; Camptothecin
Keywords: کامپتوتسین ; SiNPs; silica nanoparticles; MSNs; mesoporous silica nanoparticles; C/S SiNPS; core/shell silica nanoparticle; QDs; quantum dots; MRI; magnetic resonance imaging; PET; positron emission tomography; X-ray CT; X-ray computed tomography; TEOS; tetraethyl ort
Keywords: کامپتوتسین ; ABC; adenosine triphosphate (ATP)-binding cassette; ASO; antisense oligonucleotides; CPT; camptothecin; DBD; drug-binding domain; DDS; drug delivery system; DOX; doxorubicin; EPR; enhanced permeability and retention effect; IC50 dose; a dose that kills 50
Keywords: کامپتوتسین ; Antibody drug conjugate; Camptothecin; Exatecan; Cytotoxic payload; Linker; Anti-HER2; Trastuzumab; Oncology; Cancer therapy
Curcumin sensitizes lymphoma cells to DNA damage agents through regulating Rad51-dependent homologous recombination
Keywords: کامپتوتسین ; DSB; double-strand breaks; HR; homologous recombination; NHEJ; non-homologous end-joining; PARP; poly(ADP-ribose) polymerase; PAR; poly(ADP-ribose); MTT; methyl thiazolyl; PI; propidium iodide; SD; standard deviations; SSB; single strand break; γH2AX; ph
Food-drug interactions involving multiple mechanisms: A case study with effect of Capsaicin on the pharmacokinetics of Irinotecan and its main metabolites in rat
Keywords: کامپتوتسین ; APC; 7-ethyl-10-[4-N-(5-aminopentanoic acid)-1-piperidino] carbonyloxy-camptothecin; AUC; Area under the plasma concentration-time curve; CAP; Capsaicin; CES; Carboxylesterase; CPT; Camptothecin; CPT-11; Irinotecan; CYP; cytochrome P450; DMEs; Drug-meta
Probing the evolutionary conserved residues Y204, F259, S400 and W590 that shape the catalytic groove of human TDP1 for 3â²- and 5â²-phosphodiester-DNA bond cleavage
Keywords: کامپتوتسین ; hTDP1; human tyrosyl-DNA phosphodiesterase 1; TOP1; topoisomerase I; TOP2; topoisomerase II; TOP1cc; TOP1 cleavage complex; TOP2cc; TOP2 cleavage complex; DNA damage and repair; 3â²-End blocking DNA lesions; 5â²-End blocking DNA lesions; Topoisomerases;
In vitro mass multiplication and estimation of camptothecin (CPT) in Ophiorrhiza mungos L. var. angustifolia (Thw.) Hook. f.
Keywords: کامپتوتسین ; MS; Murashige and Skoog; CPT; camptothecin; HPLC; high performance liquid chromatography; BA; benzyl adenine; 2iP; 2 isopentanyladinine; IBA; indole butyric acid; IAA; indole acetic acid; NAA; naphthalene acetic acid; Camptothecin; Ophiorrhiza; In vitro;
Roles of Alternative RNA Splicing of the Bif-1 Gene by SRRM4 During the Development of Treatment-induced Neuroendocrine Prostate Cancer
Keywords: کامپتوتسین ; Bif-1; SRRM4; Alternative RNA splicing; Neuroendocrine prostate cancer; Apoptosis; PCa; prostate cancer; t-NEPC; treatment-induced neuroendocrine prostate cancer; Bif-1; Bax-interacting factor 1; Bax; BCL-2 Associated X Protein; AdPC; prostate adenocarcin
Camptothecin loaded graphene oxide nanoparticle functionalized with polyethylene glycol and folic acid for anticancer drug delivery
Keywords: کامپتوتسین ; Graphene oxide; Polyethylene glycol; Folic acid; Anticancer; Camptothecin; Drug delivery;
The effects of nitidine chloride and camptothecin on the growth of Babesia and Theileria parasites
Keywords: کامپتوتسین ; CI; Combination index value; Cpt; Camptothecin; DA; Diminazene aceturate; DDW; Double distilled water; iRBC; Infected red blood cells; NC; Nitidine chloride; NC-IP; Nitidine chloride intraperitoneally administered; NC-Oral; Nitidine chloride orally admini
An efficient approach for the enzyme-enhanced extraction of camptothecin and 10-hydroxycamptothecin from the samara of Camptotheca acuminata using an ionic liquid solution
Keywords: کامپتوتسین ; Ionic liquid; Enzyme-enhanced extraction using ionic liquid solution (ILEEE); Camptothecin; 10-Hydroxycamptothecin; Hemicellulase; Camptotheca acuminata; Samara;
A series of camptothecin prodrugs exhibit HDAC inhibition activity
Keywords: کامپتوتسین ; Camptothecin; HDAC; SAHA; Prodrug;
DDK Has a Primary Role in Processing Stalled Replication Forks to Initiate Downstream Checkpoint Signaling
Keywords: کامپتوتسین ; DDK; CDC7-DBF4 kinase; HU; Hydroxyurea; CPT; Camptothecin;
Mesoporous silica nanoparticles for drug and gene delivery
Keywords: کامپتوتسین ; AO; acridine orange; APTES; 3-aminopropyltriethoxysilane; APTMS; amino propyl trimethoxysilane; BCL-2; B-cell lymphoma-2; BCS; Biopharmaceutical Classification System; Bio-TEM; biological transmission electron microscopy; C dots; Cornell dots; CMC; critic
Melanoma antigen-D2 controls cell cycle progression and modulates the DNA damage response
Keywords: کامپتوتسین ; APC/C; anaphase-promoting complex or cyclosome; ATM; ataxia-telangiectasia mutated protein; ATR; ataxia-telangiectasia- and rad3-related protein; CDC20; cell division cycle protein 20; CDK; cyclin-dependent kinase; CHK1; checkpoint kinase 1; CHK2; checkpo
Synthesis, crystal structure and antitumor activities of water soluble protonated salt of 20(S)-camptothecin
Keywords: کامپتوتسین ; Camptothecin; Protonated salt; Crystal structure; Antitumor;
Encapsulation of camptothecin into pegylated polyelectrolyte nanocarriers
Keywords: کامپتوتسین ; Polyelectrolyte nanocarriers; Camptothecin; Anticancer; Passive targeting; Drug delivery;
Ultrahigh-performance liquid chromatography-tandem mass spectrometry (UHPLC-MS/MS) assay for simultaneous quantifications of CZ48, lactone-stabilized camptothecin, and camptothecin and their pharmacokinetic and biliary evaluations in rats
Keywords: کامپتوتسین ; CZ48; Camptothecin; UHPLC-MS/MS; Solid phase extraction (SPE); Pharmacokinetics (PK); Biliary excretion;
6-Shogaol induces caspase-independent paraptosis in cancer cells via proteasomal inhibition
Keywords: کامپتوتسین ; 6S; 6-Shogaol; 6G; 6-Gingerol; MTT; 3-(4, 5-dimethylthiazol-2-yl)â2, 5-diphenyltetrazolium bromide; ER stress; Endoplasmic reticulum stress; UPR; Unfolded protein response; CHX; Cycloheximide; 3MA; 3 Methyl adenine; CQ; Chloroquine di phosphate; HBSS; H
Dimeric camptothecin derived phospholipid assembled liposomes with high drug loading for cancer therapy
Keywords: کامپتوتسین ; Camptothecin; Prodrug; Self-assembly; Liposome; Antitumor activity;