Autocrine motility factor stimulates the invasiveness of malignant cells as well as up-regulation of matrix metalloproteinase-3 expression via a MAPK pathway Fulltext Access 6 Pages 2008
Melanoma cell sensitivity to Docetaxel-induced apoptosis is determined by class III β-tubulin levels Fulltext Access 6 Pages 2008
Single particle analysis of thylakoid proteins from Thermosynechococcus elongatus and Synechocystis 6803: Localization of the CupA subunit of NDH-1 Fulltext Access 6 Pages 2008
Roscovitine inhibits ERK1/2 activation induced by angiotensin II in vascular smooth muscle cells Fulltext Access 6 Pages 2008
Prion protein structure is affected by pH-dependent interaction with membranes: A study in a model system Fulltext Access 6 Pages 2008
Induction of trophinin in human endometrial surface epithelia by CGβ and IL-1β Fulltext Access 6 Pages 2008
A conserved domain of herpes simplex virus ICP34.5 regulates protein phosphatase complex in mammalian cells Fulltext Access 6 Pages 2008
Cx23, a connexin with only four extracellular-loop cysteines, forms functional gap junction channels and hemichannels Fulltext Access 6 Pages 2008
Parallel increase in p70 kinase activation and tau phosphorylation (S262) with Aβ overproduction Fulltext Access 6 Pages 2008
A novel function of peroxiredoxin 1 (Prx-1) in apoptosis signal-regulating kinase 1 (ASK1)-mediated signaling pathway Fulltext Access 6 Pages 2008
Uncoupling the MgATP-induced inhibition and aggregation of Escherichia coli phosphofructokinase-2 by C-terminal mutations Fulltext Access 6 Pages 2008
Dcytb (Cybrd1) functions as both a ferric and a cupric reductase in vitro Fulltext Access 6 Pages 2008
cAMP regulates respiration and oxidative stress during rehydration in Anabaena sp. PCC 7120 Fulltext Access 6 Pages 2008
F2L, a peptide derived from heme-binding protein, inhibits LL-37-induced cell proliferation and tube formation in human umbilical vein endothelial cells Fulltext Access 6 Pages 2008
p3 peptide, a truncated form of Aβ devoid of synaptotoxic effect, does not assemble into soluble oligomers Fulltext Access 6 Pages 2008
Transcriptional regulation of the hepatocyte growth factor gene by pyrrolidine dithiocarbamate Fulltext Access 6 Pages 2008
Metabolic and signaling properties of an Itpk gene family in Glycine max Fulltext Access 6 Pages 2008
Glutamate-induced glioma cell proliferation is prevented by functional expression of the glutamate transporter GLT-1 Fulltext Access 6 Pages 2008
Tissue-specific expression of ALA synthase-1 and heme oxygenase-1 and their expression in livers of rats chronically exposed to ethanol Fulltext Access 6 Pages 2008
Adiponectin inhibits induction of TNF-α/RANKL-stimulated NFATc1 via the AMPK signaling Fulltext Access 6 Pages 2008
Mycobacterial lipomannan induces MAP kinase phosphatase-1 expression in macrophages Fulltext Access 6 Pages 2008
Processing and secretion of the N-terminal domain of α-dystroglycan in cell culture media Fulltext Access 6 Pages 2008
Sphingosine-1-phosphate induces the association of membrane-type 1 matrix metalloproteinase with p130Cas in endothelial cells Fulltext Access 6 Pages 2008
Identification of the P-TEFb complex-interacting domain of Brd4 as an inhibitor of HIV-1 replication by functional cDNA library screening in MT-4 cells Fulltext Access 6 Pages 2008
Residue 134 determines the dimer–tetramer assembly of nucleoside diphosphate kinase from moderately halophilic bacteria Fulltext Access 6 Pages 2008
The transmembrane topology of Batten disease protein CLN3 determined by consensus computational prediction constrained by experimental data Fulltext Access 6 Pages 2008
Characterization of four mammalian 3-hydroxyacyl-CoA dehydratases involved in very long-chain fatty acid synthesis Fulltext Access 6 Pages 2008
Tomatidine inhibits iNOS and COX-2 through suppression of NF-κB and JNK pathways in LPS-stimulated mouse macrophages Fulltext Access 6 Pages 2008
Rerouting of fibroblast growth factor 2 to the classical secretory pathway results in post-translational modifications that block binding to heparan sulfate proteoglycans Fulltext Access 6 Pages 2008
Molecular cloning of novel Monad binding protein containing tetratricopeptide repeat domains Fulltext Access 6 Pages 2008
Molecular mechanism of agonist recognition by the ligand-binding core of the ionotropic glutamate receptor 4 Fulltext Access 6 Pages 2008
AtTIP1;3 and AtTIP5;1, the only highly expressed Arabidopsis pollen-specific aquaporins, transport water and urea Fulltext Access 6 Pages 2008
Methanogens with pseudomurein use diaminopimelate aminotransferase in lysine biosynthesis Fulltext Access 6 Pages 2008
A strategy for screening an inhibitor of viral silencing suppressors, which attenuates symptom development of plant viruses Fulltext Access 6 Pages 2008
Activation of a Nodal-independent signaling pathway by Cripto-1 mutants with impaired activation of a Nodal-dependent signaling pathway Fulltext Access 6 Pages 2008
Thiamin-dependent transactivation activity of PDC2 in Saccharomyces cerevisiae Fulltext Access 6 Pages 2008
Adenosine A2A receptors assemble into higher-order oligomers at the plasma membrane Fulltext Access 6 Pages 2008
Features of a twin-arginine signal peptide required for recognition by a Tat proofreading chaperone Fulltext Access 6 Pages 2008
The Pf3 coat protein contacts TM1 and TM3 of YidC during membrane biogenesis Fulltext Access 6 Pages 2008
Calmodulin interacts with angiotensin-converting enzyme-2 (ACE2) and inhibits shedding of its ectodomain Fulltext Access 6 Pages 2008
Alternative mRNA splicing of SAP30L regulates its transcriptional repression activity Fulltext Access 6 Pages 2008
Decreased glucose transporters correlate to abnormal hyperphosphorylation of tau in Alzheimer disease Fulltext Access 6 Pages 2008
Spectrally silent light induced conformation change in photosynthetic reaction centers Fulltext Access 6 Pages 2008
Inhibition of the glucosyltransferase activity of clostridial Rho/Ras-glucosylating toxins by castanospermine Fulltext Access 6 Pages 2008
The pathological splicing mutation c.6792C > G in NF1 exon 37 causes a change of tenancy between antagonistic splicing factors Fulltext Access 6 Pages 2008
Identification of the fnx1+ and fnx2+ genes for vacuolar amino acid transporters in Schizosaccharomyces pombe Fulltext Access 6 Pages 2008
Spatial and temporal down-regulation of transgene expression using the TRSID-silencer in mice: Application to Prnp Fulltext Access 6 Pages 2008
AML1-ETO interacts with Sp1 and antagonizes Sp1 transactivity through RUNT domain Fulltext Access 6 Pages 2008
Thymosin β4 is involved in stabilin-2-mediated apoptotic cell engulfment Fulltext Access 6 Pages 2008
Isoform-specific interaction of pyruvate kinase with hepatitis C virus NS5B Fulltext Access 6 Pages 2008
Calcium-induced tripartite binding of intrinsically disordered calpastatin to its cognate enzyme, calpain Fulltext Access 6 Pages 2008
Effects of α-tocopherol (vitamin E) on the stability and lipid dynamics of model membranes mimicking the lipid composition of plant chloroplast membranes Fulltext Access 6 Pages 2008
Deregulation of PKN1 activity disrupts neurofilament organisation and axonal transport Fulltext Access 6 Pages 2008
Characterization of the papillomavirus α1E2 peptide unfolded to folded transition upon DNA binding Fulltext Access 6 Pages 2008
Air pollution induces enhanced mitochondrial oxidative stress in cystic fibrosis airway epithelium Fulltext Access 6 Pages 2008
Taxol and 10-deacetylbaccatinIII induce distinct changes in the dynamics of caveolae Fulltext Access 6 Pages 2008
PEG10 directly regulated by E2Fs might have a role in the development of hepatocellular carcinoma Fulltext Access 6 Pages 2008
NADPH-dependent thioredoxin reductase and 2-Cys peroxiredoxins are needed for the protection of Mg–protoporphyrin monomethyl ester cyclase Fulltext Access 6 Pages 2008
Heat shock protein 60 induces inflammatory mediators in mouse adipocytes Fulltext Access 6 Pages 2008
Syndecan-4 regulates platelet-derived growth factor-mediated MAP kinase activation by altering intracellular reactive oxygen species Fulltext Access 6 Pages 2008
Serum starvation induces H2AX phosphorylation to regulate apoptosis via p38 MAPK pathway Fulltext Access 6 Pages 2008
The ER-associated degradation component Der1p and its homolog Dfm1p are contained in complexes with distinct cofactors of the ATPase Cdc48p Fulltext Access 6 Pages 2008
Role of side-chains in the operation of the main molecular hinge of 3-phosphoglycerate kinase Fulltext Access 6 Pages 2008
Blocking mitochondrial permeability transition prevents p53 mitochondrial translocation during skin tumor promotion Fulltext Access 6 Pages 2008
Osteoporotic bone formation in mice lacking tob2; involvement of Tob2 in RANK ligand expression and osteoclasts differentiation Fulltext Access 6 Pages 2008
Extracellular catalase activity protects cysteine cathepsins from inactivation by hydrogen peroxide Fulltext Access 6 Pages 2008
Shaping dots and lines: Adding modularity into protein interaction networks using structural information Fulltext Access 6 Pages 2008
CDK5 activator p35 downregulates E-cadherin precursor independently of CDK5 Fulltext Access 6 Pages 2008
Glucuronic acid can extend O-linked core 1 glycans, but it contributes only weakly to the negative surface charge of Drosophila melanogaster Schneider-2 cells Fulltext Access 6 Pages 2008
Monitoring fibril formation of the N-terminal domain of PABPN1 carrying an alanine repeat by tryptophan fluorescence and real-time NMR Fulltext Access 6 Pages 2008
Inactivation of epoxide hydrolase by catalysis-induced formation of isoaspartate Fulltext Access 6 Pages 2008
A halorhodopsin-overproducing mutant isolated from an extremely haloalkaliphilic archaeon Natronomonas pharaonis Fulltext Access 6 Pages 2008
Interferon γ is recognised by importin α/β: Enhanced nuclear localising and transactivation activities of an interferon γ mimetic Fulltext Access 6 Pages 2008
A single residue mutation in Hha preserving structure and binding to H–NS results in loss of H–NS mediated gene repression properties Fulltext Access 6 Pages 2008
The lectin-like activity of human C1q and its implication in DNA and apoptotic cell recognition Fulltext Access 6 Pages 2008
Rapamycin reduces VEGF expression in retinal pigment epithelium (RPE) and inhibits RPE-induced sprouting angiogenesis in vitro Fulltext Access 6 Pages 2008
Dispensable residues in the active site of the cytochrome c biogenesis protein CcmH Fulltext Access 6 Pages 2008
Design of LNA-modified siRNAs against the highly structured 5′ UTR of coxsackievirus B3 Fulltext Access 6 Pages 2008
Biochemical characterisation of TCTP questions its function as a guanine nucleotide exchange factor for Rheb Fulltext Access 6 Pages 2008
Detection of higher-order G protein-coupled receptor oligomers by a combined BRET–BiFC technique Fulltext Access 6 Pages 2008
Acceptor substrate binding revealed by crystal structure of human glucosamine-6-phosphate N-acetyltransferase 1 Fulltext Access 6 Pages 2008
Increased cytoplasmic levels of CIS, SOCS1, SOCS2, or SOCS3 are required for nuclear translocation Fulltext Access 6 Pages 2008
Unscrambling thermal stability and temperature adaptation in evolved variants of a cold-active lipase Fulltext Access 6 Pages 2008