SuPr-1-mediated desumoylation regulates the repressor activity of ΔNp63α Fulltext Access 5 Pages 2007
Carbamoylphosphate serves as the source of CN−, but not of the intrinsic CO in the active site of the regulatory [NiFe]-hydrogenase from Ralstonia eutropha Fulltext Access 5 Pages 2007
The CO and CN− ligands to the active site Fe in [NiFe]-hydrogenase of Escherichia coli have different metabolic origins Fulltext Access 5 Pages 2007
Biochemical evidence for glucose-independent induction of HXT expression in Saccharomyces cerevisiae Fulltext Access 5 Pages 2007
Crystal structure of a bacterial albumin-binding domain at 1.4 Å resolution Fulltext Access 5 Pages 2007
WNK4 phosphorylates ser206 of claudin-7 and promotes paracellular Cl− permeability Fulltext Access 5 Pages 2007
Identification and characterization of an aspartyl protease from Cryptococcus neoformans Fulltext Access 5 Pages 2007
Dissecting differential binding of fructose and phosphate as leaving group/nucleophile of glucosyl transfer catalyzed by sucrose phosphorylase Fulltext Access 5 Pages 2007
Stable insertion of Alzheimer Aβ peptide into the ER membrane strongly correlates with its length Fulltext Access 5 Pages 2007
Inhibitory role of RhoA on senescence-like growth arrest by a mechanism involving modulation of phosphatase activity Fulltext Access 5 Pages 2007
p53 mediates interstitial cystitis antiproliferative factor (APF)-induced growth inhibition of human urothelial cells Fulltext Access 5 Pages 2007
Mutations of the SM protein Sly1 resulting in bypass of GTPase requirement in vesicular transport are confined to a short helical region Fulltext Access 5 Pages 2007
Prediction of three different isoforms of the human UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase Fulltext Access 5 Pages 2007
Metacaspase 2 of Trypanosoma brucei is a calcium-dependent cysteine peptidase active without processing Fulltext Access 5 Pages 2007
Regulation of the epithelial calcium channel TRPV6 by the serum and glucocorticoid-inducible kinase isoforms SGK1 and SGK3 Fulltext Access 5 Pages 2007
Chemical disulfide mapping identifies an inhibitor cystine knot in the agouti signaling protein Fulltext Access 5 Pages 2007
ZIC1 gene expression is controlled by DNA and histone methylation in mesenchymal proliferations Fulltext Access 5 Pages 2007
Hydrolysis of non-cognate aminoacyl-adenylates by a class II aminoacyl-tRNA synthetase lacking an editing domain Fulltext Access 5 Pages 2007
The effects of Group 11 transition metals, including gold, on ethylene binding to the ETR1 receptor and growth of Arabidopsis thaliana Fulltext Access 5 Pages 2007
The degree of macromolecular crowding in the cytoplasm and nucleoplasm of mammalian cells is conserved Fulltext Access 5 Pages 2007
Crystal structure of calf spleen purine nucleoside phosphorylase complexed to a novel purine analogue Fulltext Access 5 Pages 2007
Nucleolar localization of parafibromin is mediated by three nucleolar localization signals Fulltext Access 5 Pages 2007
Crystal structure of a family I.3 lipase from Pseudomonas sp. MIS38 in a closed conformation Fulltext Access 5 Pages 2007
Circulating (cell-free) nucleic acids – A promising, non-invasive tool for early detection of several human diseases Fulltext Access 5 Pages 2007
Impairment in a negative regulatory system for TCR signaling in CD4+ T cells from old mice Fulltext Access 5 Pages 2007
Amino acid residues responsible for the recognition of dichloroacetate by pyruvate dehydrogenase kinase 2 Fulltext Access 5 Pages 2007
Wnt signaling enhances the activation and survival of human hepatic stellate cells Fulltext Access 5 Pages 2007
Carboxy terminal extended phytocystatins are bifunctional inhibitors of papain and legumain cysteine proteinases Fulltext Access 5 Pages 2007
Calpastatin simultaneously binds four calpains with different kinetic constants Fulltext Access 5 Pages 2007
A soluble, magnesium-independent prenyltransferase catalyzes reverse and regular C-prenylations and O-prenylations of aromatic substrates Fulltext Access 5 Pages 2007
Oligosaccharide recognition and binding to the carbohydrate binding module of AMP-activated protein kinase Fulltext Access 5 Pages 2007
Role of Ser216 in the mechanism of action of membrane-bound lytic transglycosylase B: Further evidence for substrate-assisted catalysis Fulltext Access 5 Pages 2007
Location of PsbY in oxygen-evolving photosystem II revealed by mutagenesis and X-ray crystallography Fulltext Access 5 Pages 2007
Ligand-transporter interaction in the AcrB multidrug efflux pump determined by fluorescence polarization assay Fulltext Access 5 Pages 2007
Activation and inhibition of the proteasome by betulinic acid and its derivatives Fulltext Access 5 Pages 2007
The Ca2+-dependent exocytosis of enlargeosomes is greatly reinforced by genistein via a non-tyrosine kinase-dependent mechanism Fulltext Access 5 Pages 2007
Production of the endocannabinoids anandamide and 2-arachidonoylglycerol by endothelial progenitor cells Fulltext Access 5 Pages 2007
Changing the substrate specificity of a chitooligosaccharide oxidase from Fusarium graminearum by model-inspired site-directed mutagenesis Fulltext Access 5 Pages 2007
The C-terminus of the yeast Lsm4p is required for the association to P-bodies Fulltext Access 5 Pages 2007
The alternative complex III from Rhodothermus marinus – A prototype of a new family of quinol:electron acceptor oxidoreductases Fulltext Access 5 Pages 2007
PrrC, a Sco homologue from Rhodobacter sphaeroides, possesses thiol-disulfide oxidoreductase activity Fulltext Access 5 Pages 2007
Sialic acid is an essential moiety of mucin as a hydroxyl radical scavenger Fulltext Access 5 Pages 2007
An O2-inducible rubrerythrin-like protein, rubperoxin, is functional as a H2O2 reductase in an obligatory anaerobe Clostridium acetobutylicum Fulltext Access 5 Pages 2007
Characterization of Arabidopsis decapping proteins AtDCP1 and AtDCP2, which are essential for post-embryonic development Fulltext Access 5 Pages 2007
Protein–protein interactions in carotenoid triggered quenching of phycobilisome fluorescence in Synechocystis sp. PCC 6803 Fulltext Access 5 Pages 2007
Analogues containing the paramagnetic amino acid TOAC as substrates for angiotensin I-converting enzyme Fulltext Access 5 Pages 2007
Differential membrane perturbation caused by the cell penetrating peptide Tp10 depending on attached cargo Fulltext Access 5 Pages 2007
Molecular evolution and selection of a gene encoding two tandem microRNAs in rice Fulltext Access 5 Pages 2007
Somatostatin inhibits insulin-like growth factor-I receptor expression in the gill of a teleost fish (Oncorhynchus mykiss) Fulltext Access 5 Pages 2007
The hepatic PP1 glycogen-targeting subunit interaction with phosphorylase a can be blocked by C-terminal tyrosine deletion or an indole drug Fulltext Access 5 Pages 2007
Two neighboring residues of loop A of the α1 subunit point towards the benzodiazepine binding site of GABAA receptors Fulltext Access 5 Pages 2007
Structural basis of diversification of fungal retinal proteins probed by site-directed mutagenesis of Leptosphaeria rhodopsin Fulltext Access 5 Pages 2007
The sterol transporting heterodimer ABCG5/ABCG8 requires bile salts to mediate cholesterol efflux Fulltext Access 5 Pages 2007
α-Tocopheryl succinate inhibits angiogenesis by disrupting paracrine FGF2 signalling Fulltext Access 5 Pages 2007
mTOR is the rapamycin-sensitive kinase that confers mechanically-induced phosphorylation of the hydrophobic motif site Thr(389) in p70S6k Fulltext Access 5 Pages 2007
Post-translational modification of barley LTP1b: The lipid adduct lies in the hydrophobic cavity and alters the protein dynamics Fulltext Access 5 Pages 2007
Effects of aging and dietary restriction on ubiquitination, sumoylation, and the proteasome in the spleen Fulltext Access 5 Pages 2007
Creation of intercellular bonds by anchoring protein ligands to membranes using the diphtheria toxin T domain Fulltext Access 5 Pages 2007
The diacylglycerol forming pathways differ among floral organs of Petunia hybrida Fulltext Access 5 Pages 2007
Anti-obesity and anti-tumor pro-apoptotic peptides are sufficient to cause release of cytochrome c from vesicles Fulltext Access 5 Pages 2007
A Stargardt disease-3 mutation in the mouse Elovl4 gene causes retinal deficiency of C32–C36 acyl phosphatidylcholines Fulltext Access 5 Pages 2007
Structural basis of mercury- and zinc-conjugated complexes as SARS-CoV 3C-like protease inhibitors Fulltext Access 5 Pages 2007
Adiponectin deficiency suppresses ABCA1 expression and ApoA-I synthesis in the liver Fulltext Access 5 Pages 2007
Differential colchicine-binding across eukaryotic families: The role of highly conserved Pro268β and Ala248β residues in animal tubulin Fulltext Access 5 Pages 2007
Phorbol myristate acetate-induced Egr-1 expression is suppressed by phospholipase D isozymes in human glioma cells Fulltext Access 5 Pages 2007
Activation of prothrombin by ASP, a serine protease released from Aeromonas sobria Fulltext Access 5 Pages 2007
Cytostatic drugs differentially affect phenotypic features of porcine coronary artery smooth muscle cell populations Fulltext Access 5 Pages 2007
Dissection of the functional interaction between p53 and the embryonic proto-oncoprotein PAX3 Fulltext Access 5 Pages 2007
Epac signaling pathway involves STEF, a guanine nucleotide exchange factor for Rac, to regulate APP processing Fulltext Access 5 Pages 2007
Substitution of isoleucine L177 by histidine in Rhodobacter sphaeroides reaction center results in the covalent binding of PA bacteriochlorophyll to the L subunit Fulltext Access 5 Pages 2007
Advanced glycation end products increases matrix metalloproteinase-1, -3, and -13, and TNF-α in human osteoarthritic chondrocytes Fulltext Access 5 Pages 2007
Glucose repression over Saccharomyces cerevisiae glycerol/H+ symporter gene STL1 is overcome by high temperature Fulltext Access 5 Pages 2007
Loss of putative tumor suppressor EI24/PIG8 confers resistance to etoposide Fulltext Access 5 Pages 2007
Mechanism of vitamin D3-induced transcription of phospholipase D1 in HaCat human keratinocytes Fulltext Access 5 Pages 2007
Involvement of FpTRP26, a thioredoxin-related protein, in oxalic acid-resistance of the brown-rot fungus Fomitopsis palustris Fulltext Access 5 Pages 2007
GM1 and GM3 gangliosides highlight distinct lipid microdomains within the apical domain of epithelial cells Fulltext Access 5 Pages 2007
The Hansenula polymorpha peroxisomal targeting signal 1 receptor, Pex5p, functions as a tetramer Fulltext Access 5 Pages 2007
The surface protease PgtE of Salmonella enterica affects complement activity by proteolytically cleaving C3b, C4b and C5 Fulltext Access 5 Pages 2007
The α(1,2)-mannosidase I inhibitor 1-deoxymannojirimycin potentiates the antiviral activity of carbohydrate-binding agents against wild-type and mutant HIV-1 strains containing glycan deletions in gp120 Fulltext Access 5 Pages 2007
Rapid, transient induction of ER stress in the liver and kidney after acute exposure to heavy metal: Evidence from transgenic sensor mice Fulltext Access 5 Pages 2007
FKBP22 is part of chaperone/folding catalyst complexes in the endoplasmic reticulum of Neurospora crassa Fulltext Access 5 Pages 2007
Chromosomal size conservation through the cell cycle supports karyotype stability in Trypanosoma cruzi Fulltext Access 5 Pages 2007
Specificity of αA-crystallin binding to destabilized mutants of βB1-crystallin Fulltext Access 5 Pages 2007
An efficient chemoenzymatic production of small molecule glucosides with in situ UDP-glucose recycling Fulltext Access 5 Pages 2007