CYP2J2-derived EETs attenuated ethanol-induced myocardial dysfunction through inducing autophagy and reducing apoptosis Fulltext Access 12 Pages 2018
MitoQ improves mitochondrial dysfunction in heart failure induced by pressure overload Fulltext Access 12 Pages 2018
Nicotine induces apoptosis in human osteoblasts via a novel mechanism driven by H2O2 and entailing Glyoxalase 1-dependent MG-H1 accumulation leading to TG2-mediated NF-kB desensitization: Implication for smokers-related osteoporosis Fulltext Access 12 Pages 2018
Crosstalk between autophagy and oxidative stress regulates proteolysis in the diaphragm during mechanical ventilation Fulltext Access 12 Pages 2018
Short-term sleep deprivation with exposure to nocturnal light alters mitochondrial bioenergetics in Drosophila Fulltext Access 12 Pages 2018
Oxidants produced by methylglyoxal-modified collagen trigger ER stress and apoptosis in skin fibroblasts Fulltext Access 12 Pages 2018
Modulation of reactive oxygen species via ERK and STAT3 dependent signalling are involved in the response of mesothelioma cells to exemestane Fulltext Access 12 Pages 2018
Transient increase in sAPPα secretion in response to Aβ1-42 oligomers: an attempt of neuronal self-defense? Fulltext Access 13 Pages 2018
Hydrogen peroxide derived from NADPH oxidase 4- and 2 contributes to the endothelium-dependent vasodilatation of intrarenal arteries Fulltext Access 13 Pages 2018
Over-expression of a cardiac-specific human dopamine D5 receptor mutation in mice causes a dilated cardiomyopathy through ROS over-generation by NADPH oxidase activation and Nrf2 degradation Fulltext Access 13 Pages 2018
Cinnamic aldehyde inhibits vascular smooth muscle cell proliferation and neointimal hyperplasia in Zucker Diabetic Fatty rats Fulltext Access 13 Pages 2018
In memoriam Olivier Toussaint - Stress-induced premature senescence and the role of DNA damage Fulltext Access 13 Pages 2018
A Japanese family with mutation in the proteinase inhibitor 12 L47P gene: A case report Fulltext Access 13 Pages 2018
Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca2+/calmodulin-dependent protein kinase II Fulltext Access 13 Pages 2018
Demyelination with preferential MAG loss: A complex message from MS paraffin blocks Fulltext Access 13 Pages 2018
Curcumol induces RIPK1/RIPK3 complex-dependent necroptosis via JNK1/2-ROS signaling in hepatic stellate cells Fulltext Access 13 Pages 2018
Gut flora-dependent metabolite Trimethylamine-N-oxide accelerates endothelial cell senescence and vascular aging through oxidative stress Fulltext Access 13 Pages 2018
Myosin phosphatase accelerates cutaneous wound healing by regulating migration and differentiation of epidermal keratinocytes via Akt signaling pathway in human and murine skin Fulltext Access 13 Pages 2018
Chicoric acid prevents PDGF-BB-induced VSMC dedifferentiation, proliferation and migration by suppressing ROS/NFκB/mTOR/P70S6K signaling cascade Fulltext Access 13 Pages 2018
Pharmacological targeting of GSK-3 and NRF2 provides neuroprotection in a preclinical model of tauopathy Fulltext Access 13 Pages 2018
Autophagy regulates DUOX1 localization and superoxide production in airway epithelial cells during chronic IL-13 stimulation Fulltext Access 13 Pages 2018
High CD44 expression mediates p62-associated NFE2L2/NRF2 activation in breast cancer stem cell-like cells: Implications for cancer stem cell resistance Fulltext Access 13 Pages 2018
Butaselen prevents hepatocarcinogenesis and progression through inhibiting thioredoxin reductase activity Fulltext Access 13 Pages 2018
Early cysteine-dependent inactivation of 26S proteasomes does not involve particle disassembly Fulltext Access 13 Pages 2018
Integrated metabolic models for xenobiotic induced mitochondrial toxicity in skeletal muscle Fulltext Access 13 Pages 2018
Yap promotes hepatocellular carcinoma metastasis and mobilization via governing cofilin/F-actin/lamellipodium axis by regulation of JNK/Bnip3/SERCA/CaMKII pathways Fulltext Access 13 Pages 2018
Impaired pentose phosphate pathway in the development of 3D MCF-7 cells mediated intracellular redox disturbance and multi-cellular resistance without drug induction Fulltext Access 13 Pages 2018
MicroRNA-140-5p aggravates doxorubicin-induced cardiotoxicity by promoting myocardial oxidative stress via targeting Nrf2 and Sirt2 Fulltext Access 13 Pages 2018
SA inhibits complex III activity to generate reactive oxygen species and thereby induces GA overproduction in Ganoderma lucidum Fulltext Access 13 Pages 2018
Defective protein repair under methionine sulfoxide A deletion drives autophagy and ARE-dependent gene transcription Fulltext Access 13 Pages 2018
Sulforaphane prevents angiotensin II-induced cardiomyopathy by activation of Nrf2 via stimulating the Akt/GSK-3Ã/Fyn pathway Fulltext Access 13 Pages 2018
Inferring anatomical therapeutic chemical (ATC) class of drugs using shortest path and random walk with restart algorithms Fulltext Access 13 Pages 2018
Identification of key pathways and metabolic fingerprints of longevity in C. elegans Fulltext Access 13 Pages 2018
Adult-onset leukoencephalopathy with neuroaxonal spheroids and pigmented glia mimicking systemic lupus erythematosus cerebral vasculitis Fulltext Access 13 Pages 2018
Mutation screening of the TIA1 gene in Chinese patients with amyotrophic lateral sclerosis/frontotemporal dementia Fulltext Access 13 Pages 2018
Age at natural menopause and mortality: A survival analysis of elderly residents of São Paulo, Brazil Fulltext Access 13 Pages 2018
Mendelian adult-onset leukodystrophy genes in Alzheimer's disease: critical influence of CSF1R and NOTCH3 Fulltext Access 13 Pages 2018
Sphingosine kinase 2 cooperating with Fyn promotes kidney fibroblast activation and fibrosis via STAT3 and AKT Fulltext Access 13 Pages 2018
Crosstalk between Na+,K+-ATPase and a volume-regulated anion channel in membrane microdomains of human cancer cells Fulltext Access 13 Pages 2018
Alpha7 nicotinic acetylcholine receptor-specific agonist DMXBA (GTS-21) attenuates Aβ accumulation through suppression of neuronal γ-secretase activity and promotion of microglial amyloid-β phagocytosis and ameliorates cognitive impairment in a mouse m Fulltext Access 13 Pages 2018
The TRPM2 channel nexus from oxidative damage to Alzheimer's pathologies: An emerging novel intervention target for age-related dementia Fulltext Access 13 Pages 2018
Resolvin D1 blocks H2O2-mediated inhibitory crosstalk between SHP2 and PP2A and suppresses endothelial-monocyte interactions Fulltext Access 13 Pages 2018
Age-induced diminution of free radicals by Boeravinone B in Caenorhabditis elegans Fulltext Access 13 Pages 2018
Histone variant H2A.Z antagonizes the positive effect of the transcriptional activator CPC1 to regulate catalase-3 expression under normal and oxidative stress conditions Fulltext Access 13 Pages 2018
Oleanolic acid attenuates PCBs-induced adiposity and insulin resistance via HNF1b-mediated regulation of redox and PPARγ signaling Fulltext Access 13 Pages 2018
Small GTPases SAR1A and SAR1B regulate the trafficking of the cardiac sodium channel Nav1.5 Fulltext Access 13 Pages 2018
Repetitive TLR3 activation in the lung induces skeletal muscle adaptations and cachexia Fulltext Access 13 Pages 2018
A novel role of the mitochondrial permeability transition pore in (â)-gossypol-induced mitochondrial dysfunction Fulltext Access 14 Pages 2018
ROS and redox signaling in myocardial ischemia-reperfusion injury and cardioprotection Fulltext Access 14 Pages 2018
The influence of levodopa, entacapone and homocysteine on prevalence of polyneuropathy in patients with Parkinson's disease Fulltext Access 14 Pages 2018
Caloric restriction mitigates age-associated hippocampal differential CG and non-CG methylation Fulltext Access 14 Pages 2018
Holothuria scabra extracts possess anti-oxidant activity and promote stress resistance and lifespan extension in Caenorhabditis elegans Fulltext Access 14 Pages 2018
α-Lipoic acid improves abnormal behavior by mitigation of oxidative stress, inflammation, ferroptosis, and tauopathy in P301S Tau transgenic mice Fulltext Access 14 Pages 2018
Estimation of the glomerular filtration rate in older individuals with serum creatinine-based equations: A systematic comparison between CKD-EPI and BIS1 Fulltext Access 14 Pages 2018
Inactivation of glycogen synthase kinase 3β (GSK-3β) enhances mitochondrial biogenesis during myogenesis Fulltext Access 14 Pages 2018
Polydatin prevents fructose-induced liver inflammation and lipid deposition through increasing miR-200a to regulate Keap1/Nrf2 pathway Fulltext Access 14 Pages 2018
Acidic pHe regulates cytoskeletal dynamics through conformational integrin β1 activation and promotes membrane protrusion Fulltext Access 14 Pages 2018
A web platform for the network analysis of high-throughput data in melanoma and its use to investigate mechanisms of resistance to anti-PD1 immunotherapy Fulltext Access 14 Pages 2018
Different mitochondrial genetic defects exhibit the same protein signature of metabolism in skeletal muscle of PEO and MELAS patients: A role for oxidative stress Fulltext Access 14 Pages 2018
Sirtuin 3-dependent mitochondrial redox homeostasis protects against AGEs-induced intervertebral disc degeneration Fulltext Access 15 Pages 2018
CoQ10 supplementation rescues nephrotic syndrome through normalization of H2S oxidation pathway Fulltext Access 15 Pages 2018
Cerebellar degeneration and progressive ataxia associated with HIV-virus infection Fulltext Access 15 Pages 2018
CircSEMA4B targets miR-431 modulating IL-1β-induced degradative changes in nucleus pulposus cells in intervertebral disc degeneration via Wnt pathway Fulltext Access 15 Pages 2018
Reactive oxygen species mediate cancer stem-like cells and determine bortezomib sensitivity via Mcl-1 and Zeb-1 in mantle cell lymphoma Fulltext Access 15 Pages 2018
Unlocking the mystery of biomarkers: A brief introduction, challenges and opportunities in Parkinson Disease Fulltext Access 15 Pages 2018
Apolipoprotein A-1 mimetic peptide 4F promotes endothelial repairing and compromises reendothelialization impaired by oxidized HDL through SR-B1 Fulltext Access 15 Pages 2018
Overdosing of benzodiazepines/Z-drugs and falls in older adults: Costs for the health system Fulltext Access 15 Pages 2018
Electrical activity of sensory pathways in female and male geriatric Rhesus monkeys (Macaca mulatta), and its relation to oxidative stress Fulltext Access 15 Pages 2018
Characterization of somatostatin receptors and associated signaling pathways in pancreas of R6/2 transgenic mice Fulltext Access 15 Pages 2018
β-dystroglycan is regulated by a balance between WWP1-mediated degradation and protection from WWP1 by dystrophin and utrophin Fulltext Access 15 Pages 2018
Hyperbaric oxygen therapy ameliorates pathophysiology of 3xTg-AD mouse model by attenuating neuroinflammation Fulltext Access 15 Pages 2018
Substantia nigra fractional anisotropy changes confirm the PD at-risk status of patients with idiopathic smell loss Fulltext Access 15 Pages 2018
Intermediate-length CAG repeat in ATXN2 is associated with increased risk for amyotrophic lateral sclerosis in Brazilian patients Fulltext Access 15 Pages 2018
Breast cancer susceptibility protein 1 (BRCA1) rescues neurons from cerebral ischemia/reperfusion injury through NRF2-mediated antioxidant pathway Fulltext Access 15 Pages 2018
Therapeutic effect of Sirtuin 3 on ameliorating nonalcoholic fatty liver disease: The role of the ERK-CREB pathway and Bnip3-mediated mitophagy Fulltext Access 15 Pages 2018
High circulatory leptin mediated NOX-2-peroxynitrite-miR21 axis activate mesangial cells and promotes renal inflammatory pathology in nonalcoholic fatty liver disease Fulltext Access 15 Pages 2018
Sema3E/PlexinD1 inhibition is a therapeutic strategy for improving cerebral perfusion and restoring functional loss after stroke in aged rats Fulltext Access 15 Pages 2018
Ameliorating mitochondrial dysfunction restores carbon ion-induced cognitive deficits via co-activation of NRF2 and PINK1 signaling pathway Fulltext Access 15 Pages 2018
Brain ischemic preconditioning protects against ischemic injury and preserves the blood-brain barrier via oxidative signaling and Nrf2 activation Fulltext Access 15 Pages 2018
iNOS polymorphism modulates iNOS/NO expression via impaired antioxidant and ROS content in P. vivax and P. falciparum infection Fulltext Access 15 Pages 2018
Loss of Trem2 in microglia leads to widespread disruption of cell coexpression networks in mouse brain Fulltext Access 16 Pages 2018
Study of GCH1 and TH genes in Chinese patients with Parkinson's disease Fulltext Access 16 Pages 2018
Prostaglandin J2 promotes O-GlcNAcylation raising APP processing by α- and β-secretases: relevance to Alzheimer's disease Fulltext Access 16 Pages 2018
A glutaredoxin in the mitochondrial intermembrane space has stage-specific functions in the thermo-tolerance and proliferation of African trypanosomes Fulltext Access 16 Pages 2018
Reduction of the molecular chaperone binding immunoglobulin protein (BiP) accentuates the effect of aging on sleep-wake behavior Fulltext Access 16 Pages 2018
Toe dystonia in Parkinson's disease: Impact of subthalamic nucleus deep brain stimulation Fulltext Access 16 Pages 2018
A novel mutation in ETFDH manifesting as severe neonatal-onset multiple acyl-CoA dehydrogenase deficiency Fulltext Access 16 Pages 2018
Consensus for the measurement of the camptocormia angle in the standing patient Fulltext Access 16 Pages 2018
Putting xanthine oxidoreductase and aldehyde oxidase on the NO metabolism map: Nitrite reduction by molybdoenzymes Fulltext Access 16 Pages 2018
Cognitive profile and 18F-fluorodeoxyglucose PET study in LRRK2-related Parkinson's disease Fulltext Access 16 Pages 2018
Diagnostic criteria for camptocormia in Parkinson's disease: A consensus-based proposal Fulltext Access 16 Pages 2018
MicroRNAs mediate the senescence-associated decline of NRF2 in endothelial cells Fulltext Access 16 Pages 2018
GLUT1 protects prostate cancer cells from glucose deprivation-induced oxidative stress Fulltext Access 16 Pages 2018
Advanced oxidation protein products induce S-phase arrest of hepatocytes via the ROS-dependent, β-catenin-CDK2-mediated pathway Fulltext Access 16 Pages 2018