Cytochromes P450 and ischemic heart injury: Potential role for inhibitors in the treatment of myocardial infarction Fulltext Access 5 Pages 2005
Environmental contributions to cardiovascular disease: Particulates and ozone Fulltext Access 5 Pages 2005
Regulation of cancer cell growth and death: Evaluating new anticancer targets Fulltext Access 5 Pages 2005
In vitro characterization of radioiodinated (+)-2-[4-(4-iodophenyl) piperidino]cyclohexanol [(+)-pIV] as a sigma-1 receptor ligand Fulltext Access 5 Pages 2005
Halenaquinone and xestoquinone derivatives, inhibitors of Cdc25B phosphatase from a Xestospongia sp. Fulltext Access 5 Pages 2005
In vitro and in vivo profile of 2-(3-di-fluoromethyl-5-phenylpyrazol-1-yl)-5-methanesulfonylpyridine, a potent, selective, and orally active canine COX-2 inhibitor Fulltext Access 5 Pages 2005
A new route to trihydroxamate-containing artificial siderophores and synthesis of a new fluorescent probe Fulltext Access 5 Pages 2005
Relevance of molecular weight of chitosan and its derivatives and their antioxidant activities in vitro Fulltext Access 5 Pages 2005
Role of opiates and their receptors in the regulation of food intake and body weight Fulltext Access 5 Pages 2005
Ligands to peroxisome proliferator-activated receptors as therapeutic options for metabolic syndrome Fulltext Access 5 Pages 2005
Aldosterone synthase and mineralocorticoid receptors as targets in cardiovascular disease Fulltext Access 5 Pages 2005
A critical assessment of the potential of short interfering RNA therapeutics Fulltext Access 5 Pages 2005
The enabling technologies needed for PET-based molecular imaging to support drug development Fulltext Access 5 Pages 2005
Perspective on the status of preclinical models for psychiatric disorders Fulltext Access 5 Pages 2005
W(II)-catalyzed hydroarylation of bicyclo[2.2.1]hept-2-ene by simple arenes Fulltext Access 5 Pages 2005
Solid-phase synthesis of 2-amino-3-chloro-5- and 8-nitro-1,4-naphthoquinones: a new and general colorimetric test for resin-bound amines Fulltext Access 5 Pages 2005
A palladium Chugaev carbene complex as a modular, air-stable catalyst for Suzuki-Miyaura cross-coupling reactions Fulltext Access 5 Pages 2005
Facile catalyzed acylation of alcohols, phenols, amines and thiols based on ZrOCl2·8H2O and acetyl chloride in solution and in solvent-free conditions Fulltext Access 5 Pages 2005
Dimethylcyclam based fluoroionophore having Hg2+- and Cd2+-selective signaling behaviors Fulltext Access 5 Pages 2005
Preparation and applications of a novel bis(tributylstannyl)cyclopropane: a synthetic equivalent of a cyclopropane-1,2-dianion Fulltext Access 5 Pages 2005
Lewis acid-aldehyde-solvent interactions. A computational approach for determining the critical amount of THF molecules necessary for achieving a high enantioselection in chiral oxazaborolidinone-promoted asymmetric aldol reactions Fulltext Access 5 Pages 2005
Novel cyclo-dimerization of 1-tert-butoxycarbonyl-3-alkenylindole derivatives Fulltext Access 5 Pages 2005
Studies toward the total synthesis of di- and sesterterpenes with a dicyclopenta[a,d]cyclooctane skeleton. Construction of a versatile A/B ring building block via a ring-closing metathesis reaction and carbocationic rearrangement Fulltext Access 5 Pages 2005
Hammett 13C NMR and X-ray studies of Ï-allylpalladium phosphinooxazoline chiral ligand complexes Fulltext Access 5 Pages 2005
A family of simple amide-derived air-stable P,O-ligands for Suzuki cross-coupling of unactivated aryl chlorides Fulltext Access 5 Pages 2005
Synthetic studies on biscembranoids: asymmetric total synthesis of methyl sarcoate Fulltext Access 5 Pages 2005
3-(5-chloro-2,4-dihydroxyphenyl)-Pyrazole-4-carboxamides as inhibitors of the Hsp90 molecular chaperone Fulltext Access 5 Pages 2005
Carbonic anhydrase inhibitors: Inhibition of the human isozymes I, II, VA, and IX with a library of substituted difluoromethanesulfonamides Fulltext Access 5 Pages 2005
Synthesis and biological evaluation of methoxylated analogs of the newer generation taxoids IDN5109 and IDN5390 Fulltext Access 5 Pages 2005
Quantitative structure–activity relationship studies of vitamin D receptor affinity for analogues of 1α,25-dihydroxyvitamin D3. 1: WHIM descriptors Fulltext Access 5 Pages 2005
Novel CCR1 antagonists with oral activity in the mouse collagen induced arthritis Fulltext Access 5 Pages 2005
The Overman rearrangement in carbohydrate chemistry: stereoselective synthesis of functionalized 3-amino-3,6-dihydro-2H-pyrans and incorporation in peptide derivatives Fulltext Access 5 Pages 2005
Microwave-assisted functionalization of solid supports: application in the rapid loading of nucleosides on controlled-pore-glass (CPG) Fulltext Access 5 Pages 2005
Melleumin A, a novel peptide lactone isolated from the cultured myxomycete Physarum melleum Fulltext Access 5 Pages 2005
Generation and reactions of 3-alkylidene-1-pyrazoline radical cations by photoinduced electron transfer Fulltext Access 5 Pages 2005
Synthesis and structural analysis of isomeric pyridinophanes and thiacyclophanes Fulltext Access 5 Pages 2005
Highly efficient synthesis of 2â²,3â²-didehydro-2â²,3â²-dideoxy-β-nucleosides through a sulfur-mediated reductive 2â²,3â²-trans-elimination. From iodomethylcyclopropanes to thiirane analogs Fulltext Access 5 Pages 2005
A direct approach to α-hydroxy and α-chloro trifluoromethyl derivatives Fulltext Access 5 Pages 2005
Estrogen receptor ligands. Part 14: Application of novel antagonist side chains to existing platforms Fulltext Access 5 Pages 2005
Synthesis of α- and/or γ-benzoyloxy-α,β-enones from α-halo-α,β-enones Fulltext Access 5 Pages 2005
Synthesis and DNA binding properties of pyrrole amino acid-containing peptides Fulltext Access 5 Pages 2005
Suzuki coupling reaction for the solid-phase preparation of 5-substituted nicotinic acid derivatives Fulltext Access 5 Pages 2005
Synthesis of 1,3-enynes via Suzuki-type reaction of vinylic tellurides and potassium alkynyltrifluoroborate salts Fulltext Access 5 Pages 2005
Synthesis of isoxazoline-fused chlorins and bacteriochlorins by 1,3-dipolar cycloaddition reaction of porphyrin with nitrile oxide Fulltext Access 5 Pages 2005
Intramolecular Heck reaction strategy for the synthesis of functionalised tetrahydroanthracenes: a facile formal total synthesis of the linear abietane diterpene, umbrosone Fulltext Access 5 Pages 2005