Structural analysis of six novel oligosaccharides synthesized by glucosyl transfer from β-d-glucose 1-phosphate to raffinose and stachyose using Thermoanaerobacter brockii kojibiose phosphorylase Fulltext Access 7 Pages 2005
Mapping the hydrolytic and synthetic selectivity of a type C feruloyl esterase (StFaeC) from Sporotrichum thermophile using alkyl ferulates Fulltext Access 7 Pages 2005
New 1-amino-1-deoxy- and 2-amino-2-deoxy-polyhydroxyazepanes: synthesis and inhibition of glycosidases Fulltext Access 7 Pages 2005
Chiral 1,4-morpholin-2,5-dione derivatives as α-glucosidase inhibitors: Part 2 Fulltext Access 7 Pages 2005
Synthesis, X-ray crystallography and computational studies concerning an oxadiazinone derived from d-camphor: a structural limitation of oxadiazinones as chiral auxiliaries Fulltext Access 7 Pages 2005
Diastereoselective formation of α-aminoamides from carbamoylsilanes and aldehyde imines Fulltext Access 7 Pages 2005
Asymmetric synthesis using hydrolytic enzymes in supercritical carbon dioxide Fulltext Access 7 Pages 2005
The l-enantiomers of d-sugar-mimicking iminosugars are noncompetitive inhibitors of d-glycohydrolase? Fulltext Access 7 Pages 2005
Stereocontrolled transformation of nitrohexofuranoses into cyclopentylamines via 2-oxabicyclo[2.2.1]heptanes. Part 2: Synthesis of (1S,2R,3S,4S,5R)-3,4,5-trihydroxy-2-aminocyclopentanecarboxylic acid Fulltext Access 7 Pages 2005
Synthesis of stereoregular poly-O-methyl-d- and l-polygalactonamides as nylon 6 analogues Fulltext Access 7 Pages 2005
Enzymatic synthesis of alkyl α-2-deoxyglucosides by alkyl alcohol resistant α-glucosidase from Aspergillus niger Fulltext Access 7 Pages 2005
Catalytic, asymmetric aza-Baylis-Hillman reaction of N-sulfonated imines with 2-cyclohexen-1-one and 2-cyclopenten-1-one in the presence of a chiral phosphine Lewis base Fulltext Access 7 Pages 2005
Organocatalytic transformation of 1,3-diketones into optically active cyclohexanones Fulltext Access 7 Pages 2005
Design and synthesis of a novel neo-glycolipid containing sialyl Lewis X determinant carried on the mucin GlcNAcβ1-6GalNAcα core structure Fulltext Access 7 Pages 2005
Chiral bis(amino alcohol)oxalamides as ligands for asymmetric catalysis. Ti(IV) catalyzed enantioselective addition of diethylzinc to aldehydes Fulltext Access 7 Pages 2005
Lipase-catalyzed separation of the enantiomers of 1-substituted-3-arylthio-2-propanols Fulltext Access 7 Pages 2005
C2-Symmetric bicyclo[3.3.1]nona-2,6-diene and bicyclo[3.3.2]deca-2,6-diene: new chiral diene ligands based on the 1,5-cyclooctadiene framework Fulltext Access 7 Pages 2005
Synthesis of E-vinylogous (R)-amino acid derivatives via metal-catalyzed allylic substitutions on enzyme-derived substrates Fulltext Access 7 Pages 2005
Polymer-supported chiral sulfonamide catalyzed one-pot reduction of β-keto nitriles: a practical synthesis of (R)-fluoxetine and (R)-duloxetine Fulltext Access 7 Pages 2005
Enantioselective synthesis of either enantiomer of α-alkyl-α-hydroxy-α-phenylacetic acids using chiral auxiliaries Fulltext Access 7 Pages 2005
Enantioselective alkynylations of aromatic and aliphatic aldehydes catalyzed by terpene derived chiral amino alcohols Fulltext Access 7 Pages 2005
Asymmetric synthesis of 3-hetero-substituted 2,3-dihydro-1H-isoindol-1-ones Fulltext Access 7 Pages 2005
Role of the amino sugar in the DNA binding of disaccharide anthracyclines: crystal structure of the complex MAR70/d(CGATCG) Fulltext Access 7 Pages 2005
Fancy bioisosteres: synthesis and dopaminergic properties of the endiyne FAUC 88 as a novel non-aromatic D3 agonist Fulltext Access 7 Pages 2005
Boronic acid fluorescent sensors for monosaccharide signaling based on the 6-methoxyquinolinium heterocyclic nucleus: progress toward noninvasive and continuous glucose monitoring Fulltext Access 7 Pages 2005
Synthesis and aminoacyl-tRNA synthetase inhibitory activity of aspartyl adenylate analogs Fulltext Access 7 Pages 2005
Synthesis and anticancer activity of 2-alkylaminomethyl-5-diaryl-methylenecyclopentanone hydrochlorides and related compounds Fulltext Access 7 Pages 2005
Library construction of neomycin-dipeptide heteroconjugates and selection against RRE RNA Fulltext Access 7 Pages 2005
Exploring QSAR of thiazole and thiadiazole derivatives as potent and selective human adenosine A3 receptor antagonists using FA and GFA techniques Fulltext Access 7 Pages 2005
Docking studies on PARP-1 inhibitors: insights into the role of a binding pocket water molecule Fulltext Access 7 Pages 2005
Evaluation of caffeic acid amide analogues as anti-platelet aggregation and anti-oxidative agents Fulltext Access 7 Pages 2005
Synthesis of per-sulfated flavonoids using 2,2,2-trichloro ethyl protecting group and their factor Xa inhibition potential Fulltext Access 7 Pages 2005
Quantitative structure-activity relationship to predict toxicological properties of benzene derivative compounds Fulltext Access 7 Pages 2005
Synthesis and chiral recognition of novel chiral fluorescence receptors bearing 9-anthryl moieties Fulltext Access 7 Pages 2005
Antimalarial activity of thioacridone compounds related to the acronycine alkaloid Fulltext Access 7 Pages 2005
Syntheses of C18 dibenzocyclooctadiene lignan derivatives as anti-HBsAg and anti-HBeAg agents Fulltext Access 7 Pages 2005
SAR studies of brasilicardin A for immunosuppressive and cytotoxic activities Fulltext Access 7 Pages 2005
Carbonic anhydrase inhibitors. Inhibition of Plasmodium falciparum carbonic anhydrase with aromatic sulfonamides: towards antimalarials with a novel mechanism of action? Fulltext Access 7 Pages 2005
A new strategy for glycoprotein synthesis: ligation of synthetic glycopeptides with truncated proteins expressed in E. coli as TEV protease cleavable fusion protein Fulltext Access 7 Pages 2005
Evaluation of 18F-labeled acetylcholinesterase substrates as PET radiotracers Fulltext Access 7 Pages 2005
Thi20, a remarkable enzyme from Saccharomyces cerevisiae with dual thiamin biosynthetic and degradation activities Fulltext Access 7 Pages 2005
Synthesis of sterically hindered peptide analogs using diphenyl phosphite as the coupling reagent Fulltext Access 7 Pages 2005
Stereoselective glycosylation using the long-range effect of a [2-(4-phenylbenzyl)oxycarbonyl]benzoyl group Fulltext Access 7 Pages 2005
Glycosyl thioimidates in a highly convergent one-pot strategy for oligosaccharide synthesis Fulltext Access 7 Pages 2005
Synthetic studies toward the preparation of (4R,5R)-(â)-3-[(benzyloxy)methyl]-4,5-O-isopropylidene-cyclopenten-2-one: an important synthetic intermediate for carbanucleosides Fulltext Access 7 Pages 2005
Discovery of chiral catalysts by asymmetric activation for highly enantioselective diethylzinc addition to imines: using racemic and achiral diimines as effective activators Fulltext Access 7 Pages 2005
Rhodium-catalyzed asymmetric hydroformylation of vinylarenes with novel chiral P,N-ligands derived from 1,2:5,6-di-O-cyclohexylidene-d-mannitol Fulltext Access 7 Pages 2005
A simplified synthesis of (R)-(−)-muscone using a ring-opening reaction of (R)-(+)-β-methyl-β-propiolactone Fulltext Access 7 Pages 2005
Chiral recognition in the solid state: crystallographically characterized diastereomeric co-crystals between a synthetic chiral selector (Whelk-O1) and a representative chiral analyte Fulltext Access 7 Pages 2005
Recyclable supports for stereoselective 1,3-dipolar cycloadditions: application of a fluorous oxazolidinone chiral auxiliary Fulltext Access 7 Pages 2005
Catalyzed asymmetric aryl transfer reactions to aldehydes with boroxines as aryl source Fulltext Access 7 Pages 2005
Enzymatic desymmetrization of 1,1′-methylenedi[(1R,1′S,3R,3′S,5S,5′R)-3-hydroxy-8-oxabicyclo[3.2.1]oct-6-ene-1-yl]: novel precursors of long chain polyketides Fulltext Access 7 Pages 2005
Enantioselective alkynylation and phenylation of aromatic aldehydes promoted by atropisomeric 1,1′-binaphthylazepine-based amino alcohols Fulltext Access 7 Pages 2005
Diastereoselective protonation of extended pyrrol-3-en-2-one enolates: an attempted ‘de-epimerisation’ Fulltext Access 7 Pages 2005
A novel boron trifluoride etherate mediated deep-seated rearrangement of an α,β-epoxyketone Fulltext Access 7 Pages 2005
Chiral sulfideoxathiane ligands for palladium-catalyzed asymmetric allylic alkylation Fulltext Access 7 Pages 2005
Synthesis of chiral monoaza-15-crown-5 ethers from a chiral amino alcohol and enantiomeric recognition of potassium and sodium salts of amino acids Fulltext Access 7 Pages 2005
Density functional theory study of the 5-pyrrolidin-2-yltetrazole-catalyzed aldol reaction Fulltext Access 7 Pages 2005
General strategy towards chiral methylene bis-pyrans: synthesis of the C2–C16 fragment of phorboxazole A Fulltext Access 7 Pages 2005
A C2-symmetric chiral bipyridyldiol–titanium complex as a catalyst for the asymmetric trimethylsilylcyanation of substituted benzaldehydes Fulltext Access 7 Pages 2005
Investigation of a broadly applicable chiral selector used in enantioselective chromatography (Whelk-O 1) as a chiral solvating agent for NMR determination of enantiomeric composition Fulltext Access 7 Pages 2005
Synthesis of (2R, 5S)- and (2S, 5S)-2-carboxy-1,4-diaza-[4.3.0]bicyclononane as building blocks for the synthesis of new potential HIV protease inhibitors Fulltext Access 7 Pages 2005
An efficient, asymmetric synthesis of pipecolic acid and 2-alkyl pipecolic acids Fulltext Access 7 Pages 2005
Efficient, scalable kinetic resolution of cis-4-benzyloxy-2,3-epoxybutanol Fulltext Access 7 Pages 2005
Synthesis of enantiopure 6-methoxy-2-naphthylglycolic acid and its application as a resolving agent Fulltext Access 7 Pages 2005
Asymmetric synthesis of 2′,3′-dideoxy-3′-fluoroapiofuranosyl nucleosides Fulltext Access 7 Pages 2005
Synthesis and structure–activity relationship of ethacrynic acid analogues on glutathione-s-transferase P1-1 activity inhibition Fulltext Access 7 Pages 2005
Synthesis of (3S,5S)-3,5-diaminopiperidin-2-one as a conformationally restricted surrogate of Dab-Gly dipeptide Fulltext Access 7 Pages 2005
Extension of chromatographically derived chiral recognition systems to chiral recognition and enantiomer analysis by electrospray ionization mass spectrometry Fulltext Access 7 Pages 2005
P2–P3 conformationally constrained ketoamide-based inhibitors of cathepsin K Fulltext Access 7 Pages 2005
1,8-Naphthyridin-4-one derivatives as new ligands of A2A adenosine receptors Fulltext Access 7 Pages 2005
Synthesis and evaluation of thiazole carboxamides as vanilloid receptor 1 (TRPV1) antagonists Fulltext Access 7 Pages 2005
Structural basis for the GSK-3β binding affinity and selectivity against CDK-2 of 1-(4-aminofurazan-3yl)-5-dialkylaminomethyl-1H-[1,2,3] triazole-4-carboxylic acid derivatives Fulltext Access 7 Pages 2005
RO4383596, an orally active KDR, FGFR, and PDGFR inhibitor: Synthesis and biological evaluation Fulltext Access 7 Pages 2005
Design and synthesis of a novel enediynyl pentapeptide with predominantly β-turn structural motif and its potential as a fluorescence-based chemosensor Fulltext Access 7 Pages 2005
Design and synthesis of alkyl 7,7-dihalo-3-methyl-5-(nitrophenyl)-2-azabicyclo[4.1.0]hept-3-ene-4-carboxylates with calcium channel antagonist activity Fulltext Access 7 Pages 2005
From SAR to comparative QSAR: role of hydrophobicity in the design of 4-hydroxy-5,6-dihydropyran-2-ones HIV-1 protease inhibitors Fulltext Access 7 Pages 2005
Comparison of the anti-influenza virus activity of cyclopentane derivatives with oseltamivir and zanamivir in vivo Fulltext Access 7 Pages 2005
Synthesis and biological evaluation of aromatic enones related to curcumin Fulltext Access 7 Pages 2005
The 4′,4′-difluoro analog of 5′-noraristeromycin: A new structural prototype for possible antiviral drug development toward orthopoxvirus and cytomegalovirus Fulltext Access 7 Pages 2005
Design and biological evaluation of phenyl-substituted analogs of β-phenylethylidenehydrazine Fulltext Access 7 Pages 2005
Asymmetric epoxidation of unfunctionalized olefins catalyzed by Mn(salen) axially immobilized onto insoluble polymers Fulltext Access 7 Pages 2005
Novel strategies for the preparation of aminocarbasugar analogues: syntheses of N-substituted aminocyclitols from d-mannose Fulltext Access 7 Pages 2005
Synthesis of chiral 18-crown-6 ethers containing lipophilic chains and their enantiomeric recognition of chiral ammonium picrates Fulltext Access 7 Pages 2005
Investigation of site selectivity of the stereoselective deprotonation of cyclohexene oxide using kinetic resolution of isotopic enantiomers in natural abundance Fulltext Access 7 Pages 2005