New selective acetylcholinesterase inhibitors designed from natural piperidine alkaloids Fulltext Access 7 Pages 2005
2,4,6-Trisubstituted pyrimidine derivatives as pregnancy interceptive agents Fulltext Access 7 Pages 2005
Parallel solid-phase synthesis and characterization of new sulfonamide and carboxamide proline derivatives as potential CNS agents Fulltext Access 7 Pages 2005
QSAR by LFER model of cytotoxicity data of anti-HIV 5-phenyl-1-phenylamino-1H-imidazole derivatives using principal component factor analysis and genetic function approximation Fulltext Access 7 Pages 2005
(R)-Goniothalamin: total syntheses and cytotoxic activity against cancer cell lines Fulltext Access 7 Pages 2005
Design, synthesis, and anti-tumor activity of (2-O-alkyloxime-3-phenyl)-propionyl-1-O-acetylbritannilactone esters Fulltext Access 7 Pages 2005
Isolation of brominated quinones showing chemiluminescence activity from luminous acorn worm, Ptychodera flava Fulltext Access 7 Pages 2005
Synthesis and biological evaluation of N-{4-[5-(2,4-diamino-6-oxo-1,6-dihydropyrimidin-5-yl)-2-(2,2,2-trifluoroacetyl)pentyl]benzoyl}-l-glutamic acid as a potential inhibitor of GAR Tfase and the de novo purine biosynthetic pathway Fulltext Access 7 Pages 2005
An efficient preparation of polyanionic affinity agent and its evaluation for the measurement of glycated hemoglobin Fulltext Access 7 Pages 2005
Design, synthesis and cytotoxic effect of hydroxy- and 3-alkylaminopropoxy-9,10-anthraquinone derivatives Fulltext Access 7 Pages 2005
Synthesis and vasodilatory activity of new N-acylhydrazone derivatives, designed as LASSBio-294 analogues Fulltext Access 7 Pages 2005
Correlation of LUMO localization with the α-amylase inhibition constant in a Tendamistat-based series of linear and cyclic peptides Fulltext Access 7 Pages 2005
Synthesis of a novel potent cyclic peptide MC4-ligand by ring-closing metathesis Fulltext Access 7 Pages 2005
Design and synthesis of an optimized positional scanning library of peptoids: identification of novel multidrug resistance reversal agents Fulltext Access 7 Pages 2005
Studies on quinones. Part 39: Synthesis and leishmanicidal activity of acylchloroquinones and hydroquinones Fulltext Access 7 Pages 2005
Inhibitory activity of a ceramide library on interleukin-4 production from activated T cells Fulltext Access 7 Pages 2005
Benzotropolone inhibitors of estradiol methylation: kinetics and in silico modeling studies Fulltext Access 7 Pages 2005
New sesquiterpenic phytotoxins establish unprecedented relationship between different groups of blackleg fungal isolates Fulltext Access 7 Pages 2005
Synthesis of novel DNA cross-linking antitumour agents based on polyazamacrocycles Fulltext Access 7 Pages 2005
Synthesis and evaluation of new ω-borono-α-amino acids as rat liver arginase inhibitors Fulltext Access 7 Pages 2005
The influence of aromatic residues in hydraphile spacer units: assay by ion selective electrode methods and in bacteria Fulltext Access 7 Pages 2005
Novel heterocyclic family of phenyl naphthothiazole carboxamides derived from naphthalimides: synthesis, antitumor evaluation, and DNA photocleavage Fulltext Access 7 Pages 2005
Novel coumarin-3-(N-aryl)carboxamides arrest breast cancer cell growth by inhibiting ErbB-2 and ERK1 Fulltext Access 7 Pages 2005
Three-Dimensional Visualization of Protein Expression in Mouse Brain Structures Using Imaging Mass Spectrometry Fulltext Access 7 Pages 2005
Evaluation and Optimization of Electron Capture Dissociation Efficiency in Fourier Transform Ion Cyclotron Resonance Mass Spectrometry Fulltext Access 7 Pages 2005
Identification of Anionic Supramolecular Complexes of Sulfonamide Receptors with Clâ, NO3â, Brâ, and Iâ by APCI-MS Fulltext Access 7 Pages 2005
Gas-Phase Dissociation of Oligoribonucleotides and their Analogs Studied by Electrospray Ionization Tandem Mass Spectrometry Fulltext Access 7 Pages 2005
The Cationization Mechanism Study of Novel Oligo (p-phenyleneethynylene)s Fulltext Access 7 Pages 2005
Structure Elucidation of Degradation Products of the Antibiotic Amoxicillin with Ion Trap MSn and Accurate Mass Determination by ESI TOF Fulltext Access 7 Pages 2005
Does Double Electron Capture Lead to the Formation of Biradicals? An ECD-SORI-CID Study on Lacticin 481 Fulltext Access 7 Pages 2005
Automated nanospray using chip-based emitters for the quantitative analysis of pharmaceutical compounds Fulltext Access 7 Pages 2005
Immobilized carbon nanotubes as matrix for MALDI-TOF-MS analysis: Applications to neutral small carbohydrates Fulltext Access 7 Pages 2005
LCMS/MS and TOF-SIMS identification of the color bodies on the surface of a polymer Fulltext Access 7 Pages 2005
Clear Evidence of Fluorescence Resonance Energy Transfer in Gas-Phase Ions Fulltext Access 7 Pages 2005
Sensitive LC MS Quantitative Analysis of Carbohydrates by Cs+ Attachment Fulltext Access 7 Pages 2005
Quantitation of synthetic polymers using an internal standard by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry Fulltext Access 7 Pages 2005
Results from a bench marking survey on supporting chemical synthesis and structural elucidation in the pharmaceutical industry Fulltext Access 7 Pages 2005
Determination of the gas-phase acidity of methylthioacetic acid using the Cooks' kinetic method Fulltext Access 7 Pages 2005
Bacterial analysis by MALDI-TOF mass spectrometry: An inter-laboratory comparison Fulltext Access 7 Pages 2005
Leveling Response Factors in the Electrospray Ionization Process Using a Heated Capillary Interface Fulltext Access 7 Pages 2005
Implementation of the bisection sampling method in path integral simulations Fulltext Access 7 Pages 2005
Analysis of actinomycin D-DNA model complexes using a quantum-chemical criterion: Mulliken overlap populations Fulltext Access 7 Pages 2005
3-Aminomethyl derivatives of 4,11-dihydroxynaphtho[2,3-f]indole-5,10-dione for circumvention of anticancer drug resistance Fulltext Access 7 Pages 2005
Catalytic enantioselective oxidation of aromatic hydrocarbons with D4-symmetric chiral ruthenium porphyrin catalysts Fulltext Access 7 Pages 2005
Synthesis, in vitro cellular uptake and photo-induced antiproliferative effects of lipophilic hypericin acid derivatives Fulltext Access 7 Pages 2005
Biological activities of retinoidal γ-hydroxybutenolides in cancer cell apoptosis and differentiation Fulltext Access 7 Pages 2005
Preliminary evaluation of the cytotoxicity of a series of tris-2-aminoethylamine (Tren) based hexadentate heterocyclic donor agents Fulltext Access 7 Pages 2005
Comparative QSAR study of phenol derivatives with the help of density functional theory Fulltext Access 7 Pages 2005
Verification of the turn at positions 22 and 23 of the β-amyloid fibrils with Italian mutation using solid-state NMR Fulltext Access 7 Pages 2005
Dihydropyrido[2,3-d]pyrimidines as a new class of antileishmanial agents Fulltext Access 7 Pages 2005
Oxidations catalyzed by phenylacetone monooxygenase from Thermobifida fusca Fulltext Access 7 Pages 2005
Enantioselective acylation of rac-2-phenylcycloalkanamines catalyzed by lipases Fulltext Access 7 Pages 2005
Enantioselective recognition by optically active chiral fluorescence sensors bearing amino acid units Fulltext Access 7 Pages 2005
Oxidation of chiral α-phenylacetate derivatives: formation of dimers with contiguous quaternary stereocenters versus tertiary alcohols Fulltext Access 7 Pages 2005
Syntheses and biological activities of daunorubicin analogs with uncommon sugars Fulltext Access 7 Pages 2005
New oxidative pathways for the synthesis of α-hydroxy ketones—the α-hydroxylation and ketohydroxylation Fulltext Access 7 Pages 2005
Asymmetric Baylis–Hillman reactions using (R)-4-(3-hydroxy-4,4-dimethyl-2-oxopyrrolidin-1-yl) benzoic acid acrylate derivatives in solution and on solid support Fulltext Access 7 Pages 2005
The natural alkaloid isoanabasine: synthesis from 2,3′-bipyridine, efficient resolution with BINOL, and assignment of absolute configuration by Mosher’s method Fulltext Access 7 Pages 2005
Neutral zinc(II) and molybdenum(0) complexes with chiral guanidine ligands: synthesis, characterisation and applications Fulltext Access 7 Pages 2005
A synthesis of levetiracetam based on (S)-N-phenylpantolactam as a chiral auxiliary Fulltext Access 7 Pages 2005
Thioamides and selenoamides with chirality solely due to hindered rotation about the C–N bond: enantioselective complexation with optically active hosts Fulltext Access 7 Pages 2005
Chemo-enzymatic synthesis of all four diastereoisomers of 1-fluoro-2-amino-indane Fulltext Access 7 Pages 2005
New chiral P-ligands: P-amino- and P-cycloalkoxy dibenzo[c.e][1,2]oxaphosphorines Fulltext Access 7 Pages 2005
A stereoselective synthesis of (2S,3R)-β-methoxyphenylalanine: a component of cyclomarin A Fulltext Access 7 Pages 2005
Laser Flash Photolysis of Hydrogen Peroxide to Oxidize Protein Solvent-Accessible Residues on the Microsecond Timescale Fulltext Access 7 Pages 2005
Synthesis, antiproliferative, and vasorelaxing evaluations of coumarin α-methylene-γ-butyrolactones Fulltext Access 7 Pages 2005
New water soluble pyrroloquinoline derivatives as new potential anticancer agents Fulltext Access 7 Pages 2005
Synthesis and conformational study of 3,4-carbocyclic bridged indole melatonin and serotonin analogues Fulltext Access 7 Pages 2005
Synthesis of some new biologically active 1,3,4-oxadiazolyl nitroindoles and a modified Fischer indole synthesis of ethyl nitro indole-2-carboxylates Fulltext Access 7 Pages 2005
Lewis acid-promoted transformation of 2-alkoxypyridines into 2-aminopyridines and their antibacterial activity. Part 2: Remarkably facile C–N bond formation Fulltext Access 7 Pages 2005
Novel thiazonaphthalimides as efficient antitumor and DNA photocleaving agents: Effects of intercalation, side chains, and substituent groups Fulltext Access 7 Pages 2005
Novel synthesis and anti-inflammatory activities of 2,5-disubstituted-dioxacycloalkanes Fulltext Access 7 Pages 2005
Improvement of ACE inhibitory activity of chitooligosaccharides (COS) by carboxyl modification Fulltext Access 7 Pages 2005
Proteins Markovian 3D-QSAR with spherically-truncated average electrostatic potentials Fulltext Access 7 Pages 2005
Amentoflavone and its derivatives as novel natural inhibitors of human Cathepsin B Fulltext Access 7 Pages 2005
Synthesis of novel 4-substituted-7-trifluoromethylquinoline derivatives with nitric oxide releasing properties and their evaluation as analgesic and anti-inflammatory agents Fulltext Access 7 Pages 2005
Effects of peripheral substituents on diastereoselectivity of the fifth ligand-binding to chlorophylls, and nomenclature of the asymmetric axial coordination sites Fulltext Access 7 Pages 2005
Synthesis of 4-pyrido-6-aryl-2-substituted amino pyrimidines as a new class of antimalarial agents Fulltext Access 7 Pages 2005
Synthesis and in vivo evaluation of a novel peripheral benzodiazepine receptor PET radioligand Fulltext Access 7 Pages 2005
Preparation and anti-inflammatory activities of diarylheptanoid and diarylheptylamine analogs Fulltext Access 7 Pages 2005
Synthesis and molecular recognition of carbohydrate-centered multivalent glycoclusters by a plant lectin RCA120 Fulltext Access 7 Pages 2005
Libertellenones A–D: Induction of cytotoxic diterpenoid biosynthesis by marine microbial competition Fulltext Access 7 Pages 2005
Chiral cruciferous phytoalexins: Preparation, absolute configuration, and biological activity Fulltext Access 7 Pages 2005
Optically active cantharidin analogues possessing selective inhibitory activity on Ser/Thr protein phosphatase 2B (calcineurin): Implications for the binding mode Fulltext Access 7 Pages 2005
Lead optimization of 7-benzyloxy 2-(4′-pyridylmethyl)thio isoflavone aromatase inhibitors Fulltext Access 7 Pages 2005
Tannins and related compounds induce nitric oxide synthase and cytokines gene expressions in Leishmania major-infected macrophage-like RAW 264.7 cells Fulltext Access 7 Pages 2005