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Daneshyari Drug Discovery Journas Latest Articles

Drug Discovery Research Articles

Dipyridyl/pyridinium thieno[2,3-b]thiophenes as new atropisomeric systems. Synthesis, conformational analysis and energy minimization
Fulltext Access 7 Pages 2005
Gas-phase thermolysis of benzotriazole derivatives. Part 3: Kinetic and mechanistic evidence for biradical intermediates in pyrolysis of aroylbenzotriazoles and related compounds
Fulltext Access 7 Pages 2005
Synthesis of pyrrolo[3,4-c]quinolines by 1,5-electrocyclisation of non-stabilised azomethine ylides
Fulltext Access 7 Pages 2005
Synthesis, characterization and photochromic studies in film of heterocycle-containing spirooxazines
Fulltext Access 7 Pages 2005
Enantioselective, (−)-sparteine-mediated deprotonation of geranyl and neryl N,N-diisopropylcarbamate: configurational stability of the intermediate lithium compounds
Fulltext Access 7 Pages 2005
Chemoselective reduction of β-butyltellanyl α,β-unsaturated carbonyl compounds to allylic alcohols
Fulltext Access 7 Pages 2005
Solvent-assisted thiocarboxylation of amines and alcohols with carbon monoxide and sulfur under mild conditions
Fulltext Access 7 Pages 2005
A facile synthesis of highly functionalized dihydrofurans based on 1,4-diazabicyclo[2.2.2]octane (DABCO) catalyzed reaction of halides with enones
Fulltext Access 7 Pages 2005
A highly fluorescent water-soluble boronic acid reporter for saccharide sensing that shows ratiometric UV changes and significant fluorescence changes
Fulltext Access 7 Pages 2005
Tautomeric enhancement of the hyperpolarizability in new acridine-benzothiazolylamine based NLO chromophores
Fulltext Access 7 Pages 2005
Iridium-catalyzed enantioselective cycloisomerization of nitrogen-bridged 1,6-enynes to 3-azabicylo[4.1.0]heptenes
Fulltext Access 7 Pages 2005
Graphical contents list
Fulltext Access 7 Pages 2005
Efficient approach to the unknown isoxazolo[3,4-d]thieno[2,3-b]pyridine system by regioselective intramolecular nitrone cycloadditions
Fulltext Access 7 Pages 2005
Model studies in the lepadin series: synthesis of enantiopure decahydroquinolines by aminocyclization of 2-(3-aminoalkyl)cyclohexenones
Fulltext Access 7 Pages 2005
Molecular structure of simple mono- and diphenyl meso-substituted porphyrin diacids: influence of protonation and substitution on the distorsion
Fulltext Access 7 Pages 2005
Comparison between polyethylenglycol and imidazolium ionic liquids as solvents for developing a homogeneous and reusable palladium catalytic system for the Suzuki and Sonogashira coupling
Fulltext Access 7 Pages 2005
Catalytic activity of η2-(olefin)palladium(0) complexes with iminophosphine ligands in the Suzuki-Miyaura reaction. Role of the olefin in the catalyst stabilization
Fulltext Access 7 Pages 2005
Synthesis of novel (NHC)Pd(acac)Cl complexes (acac=acetylacetonate) and their activity in cross-coupling reactions
Fulltext Access 7 Pages 2005
An evaluation of phosphine and carbene adducts of phosphite- and phosphinite-based palladacycles in the coupling of alkyl bromides with aryl boronic acids
Fulltext Access 7 Pages 2005
Synthesis of a novel farnesyl transferase inhibitor, ABT-100; selective preparation of a stereogenic tertiary carbinol
Fulltext Access 7 Pages 2005
Desymmetrization of spiro-activated meso-cyclopropanes via nucleophilic substitution
Fulltext Access 7 Pages 2005
A new method for the synthesis of 2-cyclopenten-1-one-5-carboxylic ester derivatives via Rh2(OAc)4-mediated intramolecular C-H insertion reaction of 4Z-β-vinyl-α-diazo β-ketoesters
Fulltext Access 7 Pages 2005
Facile synthesis and regioselective thio-Claisen rearrangements of 5-prop-2-ynyl/enyl-sulfanyl pyrimidinones: transformation to thienopyrimidinones
Fulltext Access 7 Pages 2005
Nucleophilic aromatic substitution reactions of fluorobenzenechromium complexes with P-chiral secondary phosphine-boranes: synthesis of optically pure P-chiral (dialkyl)arylphosphine-boranes
Fulltext Access 7 Pages 2005
Hemiacetal and hemiaminal formation at fluoroacyl moiety
Fulltext Access 7 Pages 2005
Oligonucleotides containing 7-propynyl-7-deazaguanine: synthesis and base pair stability
Fulltext Access 7 Pages 2005
Cyclization in situ of enose-/ynose-nitrilimines: an expedient approach to the synthesis of chiral glycopyrazoles and pyrazolonucleosides
Fulltext Access 7 Pages 2005
Graphical contents list
Fulltext Access 7 Pages 2005
Thia-acyliminium cyclisations
Fulltext Access 7 Pages 2005
Novel synthesis of 4-halo-3-hydroxy-2-pyrone: one pot rearrangement–cyclization reaction by magnesium halide
Fulltext Access 7 Pages 2005
Barbier-type reaction mediated with tin nano-particles in water
Fulltext Access 7 Pages 2005
New phenolic triterpenes from Maytenus blepharodes. Semisynthesis of 6-deoxoblepharodol from pristimerin
Fulltext Access 7 Pages 2005
Synthesis and structural revision of naturally occurring ayapin derivatives
Fulltext Access 7 Pages 2005
Nitrilimine cycloaddition onto 2-azetidinones bearing alkenyl dipolarophile(s)
Fulltext Access 7 Pages 2005
New intra-intermolecular criss-cross cycloaddition of unsymmetrical allenylazines with alkynes leading to three fused five-membered heterocycles
Fulltext Access 7 Pages 2005
Activation of chlorine and fluorine by a phenylazo group towards nucleophilic aromatic substitution. Regioselective preparation of polysubstituted anilines
Fulltext Access 7 Pages 2005
An expedient synthesis of 3-acyltetramic acids of the melophlin family from α-aminoesters and immobilized Ph3PCCO
Fulltext Access 7 Pages 2005
Copper-free palladium-catalyzed sonogashira-type coupling of aryl halides and 1-aryl-2-(trimethylsilyl)acetylenes
Fulltext Access 7 Pages 2005
Synthesis of chlorinated 2-(aminomethyl)- and 2-(alkoxymethyl)pyrroles
Fulltext Access 7 Pages 2005
Synthesis of functionalised azecine and azonine derivatives via an enolate assisted aza Claisen rearrangement
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Aspartame analogues containing 1-amino-2-phenylcyclohexanecarboxylic acids (c6Phe). Part 2
Fulltext Access 7 Pages 2005
A new route to (±)-erythro-roccellic acid and chaetomellic anhydride C through functional rearrangement, promoted by n-propylamine or CH3ONa/CH3OH, of N-propyl-3-chloro-4-dichloromethyl-3-dodecylpyrrolidin-2-one
Fulltext Access 7 Pages 2005
Tetrahedron reports on organic chemistry author index
Fulltext Access 7 Pages 2005
Synthesis of substituted uracils by the reactions of halouracils with selenium, sulfur, oxygen and nitrogen nucleophiles under focused microwave irradiation
Fulltext Access 7 Pages 2005
Silicon tetrachloride in organic synthesis: new applications for the vinylogous aldol reaction
Fulltext Access 7 Pages 2005
Palladium(II)-catalyzed heterocyclisation of 8-arylethynyl-1,2,3,4-tetrahydroquinolines: a facile route to 2-aryl-5,6-dihydro-4H-pyrrolo[3,2,1-ij]quinoline derivatives
Fulltext Access 7 Pages 2005
Nitroaldol-reaction of aldehydes in the presence of non-activated Mg:Al 2:1 hydrotalcite; a possible new mechanism for the formation of 2-aryl-1,3-dinitropropanes
Fulltext Access 7 Pages 2005
1-(4-Nitrophenoxycarbonyl)-7-pyridin-4-yl indolizine: a new versatile fluorescent building block. Application to the synthesis of a series of fluorescent β-cyclodextrins
Fulltext Access 7 Pages 2005
A convenient palladium catalyzed synthesis of symmetric biaryls, biheterocycles and biaryl chiral diamides
Fulltext Access 7 Pages 2005
Synthesis of novel 1,3,4-benzotriazepine derivatives from 4-oxo-3,1-benzoxazine and 3,1-benzothiazine-2-carbonitriles
Fulltext Access 7 Pages 2005
Radical cyclization of exo-methylene furanose derivatives: an expedient approach to the synthesis of chiral tricyclic nucleosides and benzannulated oxepine derivatives
Fulltext Access 7 Pages 2005
Tetrahedron reports on organic chemistry author index
Fulltext Access 7 Pages 2005
Thermal rearrangement of spiro[naphthalene(naphthopyranofurazan)]oxides to spiro[naphthalene(phenalenofurazan)oxides. A probable furazan oxide triggered tandem isomerisation process
Fulltext Access 7 Pages 2005
Smectic A liquid crystals from dihydrazide derivatives with lateral intermolecular hydrogen bonding
Fulltext Access 7 Pages 2005
Unexpected sulfonylamino migration in the reactions of carbazole derivatives with fluoroalkanesulfonyl azides
Fulltext Access 7 Pages 2005
A study of NMR chemical shielding in 5-coordinate phosphorus compounds (phosphoranes)
Fulltext Access 7 Pages 2005
Convenient synthesis of selectively substituted tribenzo[a,d,g]cyclononatrienes
Fulltext Access 7 Pages 2005
Lower rim substituted tert-butylcalix[4]arenes. Part 8: Calix[4]arenes with dialkoxyphosphoryl functions. Synthesis and complexing properties
Fulltext Access 7 Pages 2005
A mild, efficient and improved protocol for the synthesis of novel indolyl crown ethers, di(indolyl)pyrazolyl methanes and 3-alkylated indoles using H4[Si(W3O10)3]
Fulltext Access 7 Pages 2005
Graphical contents list
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Cinchona alkaloid phase-transfer catalysts revisited: influence of substituted aryl groups on the enantioselectivity of glycine ester enolate alkylation
Fulltext Access 7 Pages 2005
An in-depth look at the effect of Lewis acid catalysts on Diels-Alder cycloadditions in ionic liquids
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Intramolecular Diels-Alder reaction of 1,7,9-decatrienoates catalyzed by indium(III) trifluoromethanesulfonate in aqueous media
Fulltext Access 7 Pages 2005
New bioactive cyclic peroxides from the Caribbean marine sponge Plakortis zyggompha
Fulltext Access 7 Pages 2005
Automated batch scale-up of microwave-promoted Suzuki and Heck coupling reactions in water using ultra-low metal catalyst concentrations
Fulltext Access 7 Pages 2005
General synthesis of (1-substituted-1H-1,2,3-triazol-4-ylmethyl)-dialkylamines via a copper(I)-catalyzed three-component reaction in water
Fulltext Access 7 Pages 2005
Stereoselective Mannich-type reaction of chlorotitanium α-phenylseleno esters enolates with aromatic aldimines
Fulltext Access 7 Pages 2005
Solid-phase synthesis of hydroxypiperazine derivatives using phenethylamine linker by oxidation-Cope elimination
Fulltext Access 7 Pages 2005
Facile and convenient synthesis of functionalized propargylic alcohols and amines: an InBr3-Et3N reagent system promotes the alkynylation of aldehydes and N,O- or N,S-acetals
Fulltext Access 7 Pages 2005
A convenient synthesis of dihydrocoumarins from phenols and cinnamic acid derivatives
Fulltext Access 7 Pages 2005
Graphical contents list
Fulltext Access 7 Pages 2005
Synthesis of novel 1-(2,3-dihydro-5H-4,1-benzoxathiepin-3-yl)-uracil and -thymine, and their corresponding S-oxidized derivatives
Fulltext Access 7 Pages 2005
Dithionite adducts of pyridinium salts: regioselectivity of formation and mechanisms of decomposition
Fulltext Access 7 Pages 2005
Novel method for synthesis of unsymmetrical bis(indolyl)alkanes catalyzed by ceric ammonium nitrate (CAN) under ultrasonic irradiation
Fulltext Access 7 Pages 2005
Palladium mediated synthesis of isoindolinones and isoquinolinones
Fulltext Access 7 Pages 2005
Synthesis and spectroscopic studies of isosteviol-calix[4]arene and -calix[6]arene conjugates
Fulltext Access 7 Pages 2005
Synthesis of 3,3-dimethoxy-2-aryl-2,3-dihydro-1-oxa-cyclopenta[l]phenanthren-2-ols and their conversion to 2(3H)- and 3(2H)-furanones
Fulltext Access 7 Pages 2005
A spectrofluorimetric study of binary fluorophore-cyclodextrin complexes used as chiral selectors
Fulltext Access 7 Pages 2005
Poly(benzyl ether) dendrimers with strongly fluorescent distyrylbenzene cores as the fluorophores for peroxyoxalate chemiluminescence: insulating effect of dendritic structures on fluorescent sites
Fulltext Access 7 Pages 2005
Mild and efficient cyclization reaction of 2-ethynylaniline derivatives to indoles in aqueous medium
Fulltext Access 7 Pages 2005
Experimental and DFT study of the aza-Diels-Alder reaction between cyclopentadiene and protonated benzylimine derivated from glyoxylates
Fulltext Access 7 Pages 2005
Nitration of phenolic compounds by metal-modified montmorillonite KSF
Fulltext Access 7 Pages 2005
Studies on the reactions of fluoroalkanesulfonyl azide with aromatic compounds
Fulltext Access 7 Pages 2005
A novel method for synthesis of arylacetic acids from aldehydes, N-(2,3,4,6-tetra-O-pivaloylated-d-glucopyranosyl)amine and trimethylsilylcyanide
Fulltext Access 7 Pages 2005
Theoretical studies on formal hetero [3+3] cycloaddition reaction between vinylogous amide and α,β-unsaturated imine cation
Fulltext Access 7 Pages 2005
Theoretical studies on the S-N interactions in sulfoximine
Fulltext Access 7 Pages 2005
Synthetic and computational studies on intramolecular [2+2] sulfonyl isocyanate-olefin cycloadditions
Fulltext Access 7 Pages 2005
Hirsutellones A-E, antimycobacterial alkaloids from the insect pathogenic fungus Hirsutella nivea BCC 2594
Fulltext Access 7 Pages 2005
Functionalization of saturated hydrocarbons. High temperature bromination of octahydropentalene. Part 19
Fulltext Access 7 Pages 2005
I2-catalyzed Michael addition of indole and pyrrole to nitroolefins
Fulltext Access 7 Pages 2005
Efficient Pd(0)-catalyzed synthesis of 1,2,3-triazolo-3′-deoxycarbanucleosides and their analogues
Fulltext Access 7 Pages 2005
Isolation and structure of five lyngbyabellin derivatives from a Papua New Guinea collection of the marine cyanobacterium Lyngbya majuscula
Fulltext Access 7 Pages 2005
1-C-(2′-Oxoalkyl) glycosides as latent α,β-unsaturated conjugates. Synthesis of aza-C-glycosides by an intramolecular hetero-Michael addition
Fulltext Access 7 Pages 2005
BiBr3 initiated cyclization-addition reactions: effect of π-nucleophile on oxocarbenium ion addition and total syntheses of (+)-(S,S)-(cis-6-methyltetrahydropyran-2-yl)acetic acid and its trans-diastereomer
Fulltext Access 7 Pages 2005
Synthesis of (+)-agelasine C. A structural revision
Fulltext Access 7 Pages 2005
Mild and efficient direct aromatic iodination
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Tetrahedron reports on organic chemistry author index
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Comparative reactivity of N′-(5-benzoyl/ethoxycarbonyl)thiazol-2-yl-N,N-dimethylformamidines with ketenes
Fulltext Access 7 Pages 2005
Novel DNA bis-intercalators of isoquinolino[4,5-bc]acridines: design, synthesis and evaluation of cytotoxic activity
Fulltext Access 7 Pages 2005
Reaction of (2-amino-5,10,15,20-tetraphenylporphyrinato)nickel(II) with quinones
Fulltext Access 7 Pages 2005
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