Antileishmanial activity, cytotoxicity and QSAR analysis of synthetic dihydrobenzofuran lignans and related benzofurans Fulltext Access 9 Pages 2005
Structure-function relationship for saponin effects on cell cycle arrest and apoptosis in the human 1547 osteosarcoma cells: a molecular modelling approach of natural molecules structurally close to diosgenin Fulltext Access 9 Pages 2005
Design and development of a fluorescent probe for monitoring hydrogen peroxide using photoinduced electron transfer Fulltext Access 9 Pages 2005
Mechanistic study of proton transfer and hysteresis in catalytic antibody 16E7 by site-directed mutagenesis and homology modeling Fulltext Access 9 Pages 2005
Efficient fluorescent sensors of oligopeptides by dithiobis(2-benzoylamide)-bridged bis(β-cyclodextrin)s: structure in solution, binding behavior, and thermodynamic origin Fulltext Access 9 Pages 2005
Effect of Chinese medicine alpinetin on the structure of human serum albumin Fulltext Access 9 Pages 2005
Substituted propanolamines and alkylamines derived from fluoxetine as potent appetite suppressants Fulltext Access 9 Pages 2005
Design, synthesis, and biological evaluation of (E)- and (Z)-styryl-2-acetoxyphenyl sulfides and sulfones as cyclooxygenase-2 inhibitors Fulltext Access 9 Pages 2005
Comparative molecular field analysis and comparative molecular similarity indices analysis of human thymidine kinase 1 substrates Fulltext Access 9 Pages 2005
Novel thiocoumarins as inhibitors of TNF-α induced ICAM-1 expression on human umbilical vein endothelial cells (HUVECs) and microsomal lipid peroxidation Fulltext Access 9 Pages 2005
α-Glucopyranoimidazolines as intermediate analogue inhibitors of family 20 β-N-acetylglucosaminidases Fulltext Access 9 Pages 2005
Annelated pyrrolo-pyrimidines from amino-cyanopyrroles and BMMAs as leads for new DNA-interactive ring systems Fulltext Access 9 Pages 2005
Synthesis of 4-hydroxy-1-methylindole and benzo[b]thiophen-4-ol based unnatural flavonoids as new class of antimicrobial agents Fulltext Access 9 Pages 2005
Molecular docking and 3D-QSAR studies of Yersinia protein tyrosine phosphatase YopH inhibitors Fulltext Access 9 Pages 2005
Biotin-phenyldiazomethane conjugates as labeling reagents at phosphate in mono and polynucleotides Fulltext Access 9 Pages 2005
Synthesis and in vivo biodistribution of BPA-Gd-DTPA complex as a potential MRI contrast carrier for neutron capture therapy Fulltext Access 9 Pages 2005
Synthesis and in vitro evaluation of new benzovesamicol analogues as potential imaging probes for the vesicular acetylcholine transporter Fulltext Access 9 Pages 2005
Design, synthesis and photobiological properties of 3,4-cyclopentenepsoralens Fulltext Access 9 Pages 2005
Spirohydantoin derivatives of thiopyrano[2,3-b]pyridin-4(4H)-one as potent in vitro and in vivo aldose reductase inhibitors Fulltext Access 9 Pages 2005
Predicting stability of Arc repressor mutants with protein stochastic moments Fulltext Access 9 Pages 2005
Conformational sampling of the botulinum neurotoxin serotype a light chain: implications for inhibitor binding Fulltext Access 9 Pages 2005
CP-MLR directed QSAR studies on the antimycobacterial activity of functionalized alkenols-topological descriptors in modeling the activity Fulltext Access 9 Pages 2005
Stereoselective synthesis, structural characterization, and properties of 1,2-O-isopropylidene-3-C-(5-phenyl-1,2,4-oxadiazol-3-yl)-β-d-psicopyranose Fulltext Access 9 Pages 2005
Synthesis of imidazo[1,5,4-de]quinoxalin-9-ones, benzimidazole analogues of pyrroloiminoquinone marine natural products Fulltext Access 9 Pages 2005
Chalcones as potent tyrosinase inhibitors: the importance of a 2,4-substituted resorcinol moiety Fulltext Access 9 Pages 2005
Application of QSAR analysis to organic anion transporting polypeptide 1a5 (Oatp1a5) substrates Fulltext Access 9 Pages 2005
Synthesis and cytotoxic activity of N-[(alkylamino)alkyl]carboxamide derivatives of 7-oxo-7H-benz[de]anthracene, 7-oxo-7H-naphtho[1,2,3-de]quinoline, and 7-oxo-7H-benzo[e]perimidine Fulltext Access 9 Pages 2005
Synthesis and antileishmanial activities of 4,5-di-substituted acridines as compared to their 4-mono-substituted homologues Fulltext Access 9 Pages 2005
Influence of esterification and modification of A-ring in a group of lupane acids on their cytotoxicity Fulltext Access 9 Pages 2005
Selective and orally bioavailable phenylglycine tissue factor/factor VIIa inhibitors Fulltext Access 9 Pages 2005
Docking studies on monoamine oxidase-B inhibitors: Estimation of inhibition constants (Ki) of a series of experimentally tested compounds Fulltext Access 9 Pages 2005
Synthesis, acetylcholinesterase inhibition and neuroprotective activity of new tacrine analogues Fulltext Access 9 Pages 2005
Semisynthesis and biological activity of aminoacyl triesters of squamocin, an annonaceous acetogenin Fulltext Access 9 Pages 2005
The novel pyrimidine and purine derivatives of l-ascorbic acid: synthesis, one- and two-dimensional 1H and 13C NMR study, cytostatic and antiviral evaluation Fulltext Access 9 Pages 2005
Synthesis, in vitro, and in vivo characterization of an integrin αvβ3-targeted molecular probe for optical imaging of tumor Fulltext Access 9 Pages 2005
Pore formation in and enlargement of phospholipid liposomes by synthetic models of ceramides and sphingomyelin Fulltext Access 9 Pages 2005
Design, syntheses, and biological evaluations of squamostolide and its related analogs Fulltext Access 9 Pages 2005
Synthesis and evaluation of antioxidative properties of a series of organoselenium compounds Fulltext Access 9 Pages 2005
QSAR studies on some thiophene analogs as anti-inflammatory agents: enhancement of activity by electronic parameters and its utilization for chemical lead optimization Fulltext Access 9 Pages 2005
Synthesis, anti-inflammatory and analgesic activities evaluation of some mono, bi and tricyclic pyrimidine derivatives Fulltext Access 9 Pages 2005
Antiviral cyclic d,l-α-peptides: Targeting a general biochemical pathway in virus infections Fulltext Access 9 Pages 2005
Design and synthesis of labeled analogs of PhTX-56, a potent and selective AMPA receptor antagonist Fulltext Access 9 Pages 2005
Synthesis and biological evaluation of N-methyl-laudanosine iodide analogues as potential SK channel blockers Fulltext Access 9 Pages 2005
8-O-Azeloyl-14-benzoylaconine: A new alkaloid from the roots of Aconitum karacolicum Rapcs and its antiproliferative activities Fulltext Access 9 Pages 2005
Optimization of a coagulation factor VIIa inhibitor found in factor Xa inhibitor library Fulltext Access 10 Pages 2005
Human telomerase inhibition and cytotoxicity of regioisomeric disubstituted amidoanthraquinones and aminoanthraquinones Fulltext Access 10 Pages 2005
Design, development and synthesis of mixed bioconjugates of piperic acid-glycine, curcumin-glycine/alanine and curcumin-glycine-piperic acid and their antibacterial and antifungal properties Fulltext Access 10 Pages 2005
Manipulating the Fragmentation Patterns of Phosphopeptides via Gas-Phase Boron Derivatization: Determining Phosphorylation Sites in Peptides with Multiple Serines Fulltext Access 10 Pages 2005
Berberine, a strong polyriboadenylic acid binding plant alkaloid: spectroscopic, viscometric, and thermodynamic study Fulltext Access 10 Pages 2005
Facile synthesis of the heptasaccharide repeating unit of O-deacetylated GXM of C. neoformans serotype B Fulltext Access 10 Pages 2005
The discovery and preparation of disubstituted novel amino-aryl-piperidine-based renin inhibitors Fulltext Access 10 Pages 2005
Synthesis, biological evaluation and molecular modelling studies on benzothiadiazine derivatives as PDE4 selective inhibitors Fulltext Access 10 Pages 2005
In vitro evaluation of the anti-estrogenic activity of hydroxyl substituted diphenylnaphthyl alkene ligands for the estrogen receptor Fulltext Access 10 Pages 2005
Synthesis and antiviral activity of novel acyclic nucleosides in the 5-alkynyl- and 6-alkylfuro[2,3-d]pyrimidine series Fulltext Access 10 Pages 2005
Antimycobacterial compounds. Optimization of the BM 212 structure, the lead compound for a new pyrrole derivative class Fulltext Access 10 Pages 2005
Design, synthesis and preliminary biological evaluation of zatebradine analogues as potential blockers of the hyperpolarization-activated current Fulltext Access 10 Pages 2005
Cytotoxic and antitumoral properties in a series of new, ring D modified, olivacine analogues Fulltext Access 10 Pages 2005
QSTR with extended topochemical atom indices. Part 5: Modeling of the acute toxicity of phenylsulfonyl carboxylates to Vibrio fischeri using genetic function approximation Fulltext Access 10 Pages 2005
Delivery of antisense oligonucleotides to leukemia cells by RNA bacteriophage capsids Fulltext Access 10 Pages 2005
The High-Pressure Segmented Quadrupole Collision Cell (HP-SQCC) as an Ion Molecule Reactor Fulltext Access 10 Pages 2005
Simultaneous Quantification and Identification Using 18O Labeling with an Ion Trap Mass Spectrometer and the Analysis Software Application “ZoomQuant” Fulltext Access 10 Pages 2005
Analysis of Small Molecules by Ultra Thin-Layer Chromatography-Atmospheric Pressure Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Fulltext Access 10 Pages 2005
Using Oxidized Carbon Nanotubes as Matrix for Analysis of Small Molecules by MALDI-TOF MS Fulltext Access 10 Pages 2005
Organic Environments on Saturn's Moon, Titan: Simulating Chemical Reactions and Analyzing Products by FT-ICR and Ion-Trap Mass Spectrometry Fulltext Access 10 Pages 2005
Stereoselective Discrimination and Quantification of Arginine and N-Blocked Arginine Enantiomers by Formation and Dissociation of Calcium-Mediated Diastereomeric Trimer Complexes with a Chiral Reference Compound Using Electrospray Ionization-Ion Trap Tand Fulltext Access 10 Pages 2005
A genetic algorithm-based area coverage approach for controlled drug delivery using microrobots Fulltext Access 10 Pages 2005
Separation of Sodiated Isobaric Disaccharides and Trisaccharides Using Electrospray Ionization-Atmospheric Pressure Ion Mobility-Time of Flight Mass Spectrometry Fulltext Access 10 Pages 2005
In situ sensing and manipulation of molecules in biological samples using a nanorobotic system Fulltext Access 10 Pages 2005
Structure and property correlation for Ag deposition on α-Al2O3-a first principle study Fulltext Access 10 Pages 2005
Inhibitor-based validation of a homology model of the active-site of tripeptidyl peptidase II Fulltext Access 10 Pages 2005
Scoring binding affinity of multiple ligands using implicit solvent and a single molecular dynamics trajectory: Application to Influenza neuraminidase Fulltext Access 10 Pages 2005
Development of parameter sets for semi-empirical MO calculations of transition metal systems: Iron parameters for iron-sulfur proteins Fulltext Access 10 Pages 2005
Insights into the induced fit mechanism in antithrombin-heparin interaction using molecular dynamics simulations Fulltext Access 10 Pages 2005
Charge state-dependent fragmentation of oligonucleotide/metal complexes Fulltext Access 10 Pages 2005
QSAR analyses on ginkgolides and their analogues using CoMFA, CoMSIA, and HQSAR Fulltext Access 10 Pages 2005
Cyclic sulfamide HIV-1 protease inhibitors, with sidechains spanning from P2/P2â² to P1/P1â² Fulltext Access 10 Pages 2005
Synthesis and structure-activity relationships of benzyloxyphenyl derivatives as a novel class of NCX inhibitors: effects on heart failure Fulltext Access 10 Pages 2005
Synthesis, biological evaluation, and molecular modeling of novel thioacridone derivatives related to the anticancer alkaloid acronycine Fulltext Access 10 Pages 2005
Electrospray Mass Spectrometry for the Direct Accurate Mass Measurement of Ligands in Complex With the Retinoid X Receptor α Ligand Binding Domain Fulltext Access 10 Pages 2005
Improved Sensitivity and Mass Range in Time-of-Flight Bioaerosol Mass Spectrometry Using an Electrostatic Ion Guide Fulltext Access 10 Pages 2005
Generation of Peptide Radical Dications via Low-Energy Collision-Induced Dissociation of [CuII(terpy)(M + H)]·3+ Fulltext Access 10 Pages 2005
Evaluation of protein-DNA binding affinity by electrospray ionization mass spectrometry Fulltext Access 10 Pages 2005
Identification of the minimal glycopeptide core recognized by T cells in a model for rheumatoid arthritis Fulltext Access 10 Pages 2005
Automatic gain control in mass spectrometry using a jet disrupter electrode in an electrodynamic ion funnel1 Fulltext Access 10 Pages 2005
Analysis of homoisoflavonoids in Ophiopogon japonicus by HPLC-DAD-ESI-MSn1 Fulltext Access 10 Pages 2005
Binding of gaseous Fe(III)-heme cation to model biological molecules: Direct association and ligand transfer reactions Fulltext Access 10 Pages 2005
Screening and sequencing of complex sialylated and sulfated glycosphingolipid mixtures by negative ion electrospray Fourier transform ion cyclotron resonance mass spectrometry Fulltext Access 10 Pages 2005
Statistical evaluation of electrospray tandem mass spectra for optimized peptide fragmentation Fulltext Access 10 Pages 2005
The relative influences of acidity and polarity on responsiveness of small organic molecules to analysis with negative ion electrospray ionization mass spectrometry (ESI-MS) Fulltext Access 10 Pages 2005
An Investigation of Enhanced Secondary Ion Emission Under Aun+ (n = 1-7) Bombardment Fulltext Access 10 Pages 2005