Application of an In Vitro Dissolution/Permeation System to Early Screening of Oral Formulations of Poorly Soluble, Weakly Basic Drugs Containing an Acidic pH-Modifier Fulltext Access 7 Pages 2018
GABAA receptors in the ventral tegmental area control the outcome of a social competition in rats Fulltext Access 7 Pages 2018
The highly selective 5-HT2A antagonist EMD-281,014 reduces dyskinesia and psychosis in the l-DOPA-treated parkinsonian marmoset Fulltext Access 7 Pages 2018
Active Mediated Transport of Chloramphenicol and Thiamphenicol in a Calu-3 Lung Epithelial Cell Model Fulltext Access 7 Pages 2018
Rapid, Room Temperature Nanoparticle Drying and Low-Energy Reconstitution via Electrospinning Fulltext Access 7 Pages 2018
Inhibition of CYP3A by Antimalarial Piperaquine and Its Metabolites in Human Liver Microsomes With IVIV Extrapolation Fulltext Access 7 Pages 2018
Simultaneous Retrodialysis by Calibrator for Rapid In Vivo Recovery Determination in Target Site Microdialysis Fulltext Access 7 Pages 2018
Development, Characterization, and In Vitro Testing of Co-Delivered Antimicrobial Dry Powder Formulation for the Treatment of Pseudomonas aeruginosa Biofilms Fulltext Access 7 Pages 2018
Biopharmaceutical Characterization and Oral Efficacy of a New Rapid Acting Antidepressant Ro 25-6981 Fulltext Access 7 Pages 2018
Exposure to cannabinoid agonist WIN 55,212-2 during early adolescence increases alcohol preference and anxiety in CD1 mice Fulltext Access 7 Pages 2018
Radical scavenging potential, antiinflammatory and antiarthritic activity of isolated isomer Methyl-γ-Orsellinate and roccellatol from Roccella montagnei Bel Fulltext Access 7 Pages 2018
Chronomodulated drug delivery system of Irbesartan: Formulation and development using Desing of Experiment (DoE) Fulltext Access 7 Pages 2018
Hypnose médicale et douleur. Point de vue d'un rhumatologue. Questions posées au Dr Eric Gibert Fulltext Access 7 Pages 2018
Rapid and sensitive liquid chromatography-tandem mass spectrometric method for the quantitative determination of potentially harmful substance 5,5â²-oxydimethylenebis (2-furfural) in traditional Chinese medicine injections Fulltext Access 7 Pages 2018
Separation and simultaneous quantitation of PGF2α and its epimer 8-iso-PGF2α using modifier-assisted differential mobility spectrometry tandem mass spectrometry Fulltext Access 7 Pages 2018
Coronaridine congeners modulate mitochondrial α3β4* nicotinic acetylcholine receptors with different potency and through distinct intra-mitochondrial pathways Fulltext Access 7 Pages 2018
Internet as a source of medicines information (MI) among frequent internet users Fulltext Access 7 Pages 2018
Acamprosate's ethanol intake-reducing effect is associated with its ability to increase dopamine Fulltext Access 7 Pages 2018
Serotonin transporter occupancy by the SSRI citalopram predicts default-mode network connectivity Fulltext Access 7 Pages 2018
The inclusion complex of carvacrol and β-cyclodextrin reduces acute skeletal muscle inflammation and nociception in rats Fulltext Access 7 Pages 2018
Toxicity of the biocide polycarbamate, used for aquaculture nets, to some marine fish species Fulltext Access 7 Pages 2018
Functional suppression of macrophages derived from THP-1 cells by environmentally-relevant concentrations of arsenite Fulltext Access 7 Pages 2018
Les nouveaux médicaments en gastro-entérologie, métabolisme-nutrition et pneumologie Fulltext Access 7 Pages 2018
Study of forced degradation behavior of pramlintide acetate by HPLC and LC-MS Fulltext Access 7 Pages 2018
Simultaneous determination of four amides in Saururus chinensis by matrix solid phase dispersion and high-performance liquid chromatography method Fulltext Access 7 Pages 2018
Ceratonia siliqua honeys from Morocco: Physicochemical properties, mineral contents, and antioxidant activities Fulltext Access 7 Pages 2018
A validated capillary electrophoretic method for the determination of indacaterol and its application to a pharmaceutical preparation Fulltext Access 7 Pages 2018
Characterization of key aroma-active compounds in lychee (Litchi chinensis Sonn.) Fulltext Access 7 Pages 2018
Where are they now? Retention strategies over 25 years in the Coronary Artery Risk Development in Young Adults (CARDIA) Study Fulltext Access 7 Pages 2018
Design of an experimental protocol to examine medication non-adherence among young drivers diagnosed with ADHD: A driving simulator study Fulltext Access 7 Pages 2018
Modulation of GABA and glycine receptors in rat pyramidal hippocampal neurones by 3α5β-pregnanolone derivatives Fulltext Access 7 Pages 2018
Different response of acetylcholinesterases in salt- and detergent-soluble fractions of honeybee haemolymph, head and thorax after exposure to diazinon Fulltext Access 7 Pages 2018
Molecular characterization and metal induced gene expression of the novel glutathione peroxidase 7 from the chordate invertebrate Ciona robusta Fulltext Access 7 Pages 2018
Human-cell-derived organoids as a new ex vivo model for drug assays in oncology Fulltext Access 7 Pages 2018
Toxic responses of Sox2 gene in the regeneration of the earthworm Eisenia foetida exposed to Retnoic acid Fulltext Access 7 Pages 2018
Chronic treatment with a MEK inhibitor reverses enhanced excitatory field potentials in Syngap1+/â mice Fulltext Access 7 Pages 2018
Modifying the physicochemical properties of NSAIDs for nasal and pulmonary administration Fulltext Access 7 Pages 2018
Repositioning of molsidomine for its efficacy in diabetes induced erectile dysfunction in rats: In silico, in vitro and in vivo approach Fulltext Access 7 Pages 2018
Quantitative analysis of in-vivo responses of reproductive and thyroid endpoints in male goldfish exposed to monocrotophos pesticide Fulltext Access 7 Pages 2018
Metal accumulation and expression of genes encoding for metallothionein and copper transporters in a chronically exposed wild population of the fish Hyphessobrycon luetkenii Fulltext Access 7 Pages 2018
Assessment of depression-like behavior and anhedonia after repeated cycles of binge-like ethanol drinking in male C57BL/6J mice Fulltext Access 7 Pages 2018
Effect of dietary alanyl-glutamine dipeptide against chronic ammonia stress induced hyperammonemia in the juvenile yellow catfish (Pelteobagrus fulvidraco) Fulltext Access 7 Pages 2018
The thiol switch C684 in Mitofusin-2 mediates redox-induced alterations of mitochondrial shape and respiration Fulltext Access 7 Pages 2018
FGIN-1-27, an agonist at translocator protein 18â¯kDa (TSPO), produces anti-anxiety and anti-panic effects in non-mammalian models Fulltext Access 8 Pages 2018
Relationship between CYP3A29 and pregnane X receptor in landrace pigs: Pig CYP3A29 has a similar mechanism of regulation to human CYP3A4 Fulltext Access 8 Pages 2018
Immunomodulatory effect of Celecoxib on HMGB1/TLR4 pathway in a recurrent seizures model in immature rats Fulltext Access 8 Pages 2018
S-allyl cysteine ameliorates cyclophosphamide-induced downregulation of urothelial uroplakin IIIa with a concomitant effect on expression and release of CCL11and TNF-α in mice Fulltext Access 8 Pages 2018
Two common mild analgesics have no effect on general endocrine mediated endpoints in zebrafish (Danio rerio) Fulltext Access 8 Pages 2018
Transcriptomic approach: A promising tool for rapid screening nanomaterial-mediated toxicity in the marine bivalve Mytilus edulis-Application to copper oxide nanoparticles Fulltext Access 8 Pages 2018
Drug-Disease Interaction: Effect of Inflammation and Nonsteroidal Anti-Inflammatory Drugs on Cytochrome P450 Metabolites of Arachidonic Acid Fulltext Access 8 Pages 2018
Evidence That P-glycoprotein Inhibitor (Elacridar)-Loaded Nanocarriers Improve Epidermal Targeting of an Anticancer Drug via Absorptive Cutaneous Transporters Inhibition Fulltext Access 8 Pages 2018
Glyphosate-based herbicides modulate oxidative stress response in the nematode Caenorhabditis elegans Fulltext Access 8 Pages 2018
Agmatine inhibits nicotine withdrawal induced cognitive deficits in inhibitory avoidance task in rats: Contribution of α2-adrenoceptors Fulltext Access 8 Pages 2018
Quantitative temporal changes in DTI values coupled with histological properties in cuprizone-induced demyelination and remyelination Fulltext Access 8 Pages 2018
Investigation and molecular docking studies of Bassianolide from Lecanicillium lecanii against Plutella xylostella (Lepidoptera: Plutellidae) Fulltext Access 8 Pages 2018
Involvement of vascular endothelial growth factor (VEGF) and mitogen-activated protein kinases (MAPK) in the mechanism of neuroleptic drugs Fulltext Access 8 Pages 2018
Comparison of xenobiotic metabolism in phase I oxidation and phase II conjugation between rats and bird species Fulltext Access 8 Pages 2018
Toward an adverse outcome pathway for impaired growth: Mitochondrial dysfunction impairs growth in early life stages of the fathead minnow (Pimephales promelas) Fulltext Access 8 Pages 2018
The effects of donepezil on phencyclidine-induced cognitive deficits in a mouse model of schizophrenia Fulltext Access 8 Pages 2018
Does size matter? Venom proteomic and functional comparison between night adder species (Viperidae: Causus) with short and long venom glands Fulltext Access 8 Pages 2018
Dipalmitoylphosphatidylcholine (DPPC): Annealing Strategy to Mitigate Variability in Thermotropic and Moisture Sorption Behavior Fulltext Access 8 Pages 2018
Effects of calcium and estrogen on the development of the ceratohyal cartilage in zebrafish (Danio rerio) larvae upon embryo and maternal cadmium exposure Fulltext Access 8 Pages 2018
Silencing of HIF-1 in WSSV-infected white shrimp: Effect on viral load and antioxidant enzymes Fulltext Access 8 Pages 2018
Repeated peripheral administration of lipidized prolactin-releasing peptide analog induces c-fos and FosB expression in neurons of dorsomedial hypothalamic nucleus in male C57 mice Fulltext Access 8 Pages 2018
Lanthionine ketimine-5-ethyl ester provides neuroprotection in a zebrafish model of okadaic acid-induced Alzheimer's disease Fulltext Access 8 Pages 2018
Concerted action of dipeptidyl peptidase IV and glutaminyl cyclase results in formation of pyroglutamate-modified amyloid peptides in vitro Fulltext Access 8 Pages 2018
A brain-specific isoform of apoptosis-inducing factor 2 attenuates ischemia-induced oxidative stress in HT22 cells Fulltext Access 8 Pages 2018
P2Y12 shRNA treatment relieved HIV gp120-induced neuropathic pain in rats Fulltext Access 8 Pages 2018
A novel nitroreductase-enhanced MRI contrast agent and its potential application in bacterial imaging Fulltext Access 8 Pages 2018
Implantable sandwich PHBHHx film for burst-free controlled delivery of thymopentin peptide Fulltext Access 8 Pages 2018
Integrated metabolomic and transcriptomic analyses revealed the distribution of saponins in Panax notoginseng Fulltext Access 8 Pages 2018
Protein kinase C-mediated impairment of glutamine outward transport and SN1 transporter distribution by ammonia in mouse cortical astrocytes Fulltext Access 8 Pages 2018
Manipulating the epigenome for the treatment of disorders with thrombotic complications Fulltext Access 8 Pages 2018
Botanical and genetic characterization of Hydrocotyle umbellata L. cultivated in Egypt Fulltext Access 8 Pages 2018
Early paracetamol exposure decreases brain-derived neurotrophic factor (BDNF) in striatum and affects social behaviour and exploration in rats Fulltext Access 8 Pages 2018
Addition of Cationic Surfactants to Lipid-Based Formulations of Poorly Water-Soluble Acidic Drugs Alters the Phase Distribution and the Solid-State Form of the Precipitate Upon In Vitro Lipolysis Fulltext Access 8 Pages 2018
ATR-FTIR Characterization of Janus Nanoparticles. Part I: Implementation of Spectroscopic Descriptors Fulltext Access 8 Pages 2018
Microarray patches: potentially useful delivery systems for long-acting nanosuspensions Fulltext Access 8 Pages 2018
Retina Compatible Interactions and Effective Modulation of Blood Ocular Barrier P-gp Activity by Third-Generation Inhibitors Improve the Ocular Penetration of Loperamide Fulltext Access 8 Pages 2018
Development of a New Punch Head Shape to Replicate Scale-Up Issues on a Laboratory Tablet Press III: Replicating Sticking Phenomenon Using the SAS Punch and Evaluation by Checking the Tablet Surface Using 3-D Laser Scanning Microscope Fulltext Access 8 Pages 2018
Drug targeting of one or more aminoacyl-tRNA synthetase in the malaria parasite Plasmodium falciparum Fulltext Access 8 Pages 2018
Proliferation, Metabolic Activity, and Adipogenic Differentiation of Human Preadipocytes Exposed to 2 Surfactants In Vitro Fulltext Access 8 Pages 2018
The Effect of Drug Content Reduction on the In Vitro and In Vivo Properties of Levonorgestrel-Releasing Intravaginal Rings Fulltext Access 8 Pages 2018
Investigating the metabolic alterations in a depressive-like rat model of chronic forced swim stress: An in vivo proton magnetic resonance spectroscopy study at 7T Fulltext Access 8 Pages 2018
Effects of para-methoxyamphetamine (PMA) on agonistic encounters between male mice Fulltext Access 8 Pages 2018