RIP3-deficience attenuates potassium oxonate-induced hyperuricemia and kidney injury Fulltext Access 10 Pages 2018
The natural phenolic peperobtusin A induces apoptosis of lymphoma U937 cells via the Caspase dependent and p38 MAPK signaling pathways Fulltext Access 10 Pages 2018
Ebselen can Protect Male Reproductive Organs and Male Fertility from Manganese Toxicity: Structural and Bioanalytical Approach in a Rat Model Fulltext Access 10 Pages 2018
Synthesis and antinociceptive evaluation of bioisosteres and hybrids of naproxen, ibuprofen and paracetamol Fulltext Access 10 Pages 2018
Dihydromyricetin ameliorates foam cell formation via LXRα-ABCA1/ABCG1-dependent cholesterol efflux in macrophages Fulltext Access 10 Pages 2018
miR-566 functions as an oncogene and a potential biomarker for prognosis in renal cell carcinoma Fulltext Access 10 Pages 2018
EFLDO induces apoptosis in hepatic cancer cells by caspase activation in vitro and suppresses tumor growth in vivo Fulltext Access 10 Pages 2018
Moringa concanensis Nimmo ameliorates hyperglycemia in 3T3-L1 adipocytes by upregulating PPAR-γ, C/EBP-α via Akt signaling pathway and STZ-induced diabetic rats Fulltext Access 10 Pages 2018
Sirtuin7 has an oncogenic potential via promoting the growth of cholangiocarcinoma cells Fulltext Access 10 Pages 2018
Long noncoding RNA maternally expressed gene 3 knockdown alleviates lipopolysaccharide-induced inflammatory injury by up-regulation of miR-203 in ATDC5 cells Fulltext Access 10 Pages 2018
Tea polysaccharide inhibits RANKL-induced osteoclastogenesis in RAW264.7 cells and ameliorates ovariectomy-induced osteoporosis in rats Fulltext Access 10 Pages 2018
25-Hydroxyl-protopanaxatriol protects against H2O2-induced H9c2 cardiomyocytes injury via PI3K/Akt pathway and apoptotic protein down-regulation Fulltext Access 10 Pages 2018
p-Coumaric acid mediated protection of H9c2 cells from Doxorubicin-induced cardiotoxicity: Involvement of augmented Nrf2 and autophagy Fulltext Access 10 Pages 2018
Differential expression of the receptors for thyroid hormone, thyroid stimulating hormone, vitamin D and retinoic acid and extracellular signal-regulated kinase in uterus of rats under influence of sex-steroids Fulltext Access 10 Pages 2018
VS-5584 as a PI3K/mTOR inhibitor enhances apoptotic effects of subtoxic dose arsenic trioxide via inhibition of NF-κB activity in B cell precursor-acute lymphoblastic leukemia Fulltext Access 10 Pages 2018
Polysaccharide isolated from Aloe vera gel suppresses ovalbumin-induced food allergy through inhibition of Th2 immunity in mice Fulltext Access 10 Pages 2018
Annona muricata Linn. leaf as a source of antioxidant compounds with in vitro antidiabetic and inhibitory potential against α-amylase, α-glucosidase, lipase, non-enzymatic glycation and lipid peroxidation Fulltext Access 10 Pages 2018
Betulinic acid attenuates dexamethasone-induced oxidative damage through the JNK-P38 MAPK signaling pathway in mice Fulltext Access 10 Pages 2018
Effects of tocotrienol from Bixa orellana (annatto) on bone histomorphometry in a male osteoporosis model induced by buserelin Fulltext Access 10 Pages 2018
The chemotherapeutic effect of β-2-himachalen-6-ol in chemically induced skin tumorigenesis Fulltext Access 10 Pages 2018
Involvement of estrogen receptors in silibinin protection of pancreatic β-cells from TNFα- or IL-1β-induced cytotoxicity Fulltext Access 10 Pages 2018
Inhibition of class IIa histone deacetylase activity by gallic acid, sulforaphane, TMP269, and panobinostat Fulltext Access 10 Pages 2018
β-asarone induces cell apoptosis, inhibits cell proliferation and decreases migration and invasion of glioma cells Fulltext Access 10 Pages 2018
Antinociceptive, anti-inflammatory and toxicological evaluation of semi-synthetic molecules obtained from a benzyl-isothiocyanate isolated from Moringa oleifera Lam. in a temporomandibular joint inflammatory hypernociception model in rats Fulltext Access 10 Pages 2018
Development and validation of a Fast gas chromatography/mass spectrometry method for the determination of cannabinoids in Cannabis sativa L Fulltext Access 10 Pages 2018
A paeonol derivative, YPH-PA3 promotes the differentiation of monocyte/macrophage lineage precursor cells into osteoblasts and enhances their autophagy Fulltext Access 10 Pages 2018
Synergistic action of ursolic acid and metformin in experimental model of insulin resistance and related behavioral alterations Fulltext Access 10 Pages 2018
DHA attenuates hepatic ischemia reperfusion injury by inhibiting pyroptosis and activating PI3K/Akt pathway Fulltext Access 10 Pages 2018
Mechanisms and therapeutic targets for bone damage in rheumatoid arthritis, in particular the RANK-RANKL system Fulltext Access 10 Pages 2018
Novel approach to temozolomide resistance in malignant glioma: connexin43-directed therapeutics Fulltext Access 10 Pages 2018
Therapeutic potential of pancreatic PAX4-regulated pathways in treating diabetes mellitus Fulltext Access 10 Pages 2018
MiR-21 promotes ECM degradation through inhibiting autophagy via the PTEN/akt/mTOR signaling pathway in human degenerated NP cells Fulltext Access 10 Pages 2018
Oroxylin A suppresses influenza A virus replication correlating with neuraminidase inhibition and induction of IFNs Fulltext Access 10 Pages 2018
In vitro and in vivo immunomodulatory potential of Pedicularis longiflora and Allium carolinianum in alloxan-induced diabetes in rats Fulltext Access 10 Pages 2018
Lipid rafts disruption induces apoptosis by attenuating expression of LRP6 and survivin in triple negative breast cancer Fulltext Access 10 Pages 2018
Kockdown of OIP5-AS1 expression inhibits proliferation, metastasis and EMT progress in hepatoblastoma cells through up-regulating miR-186a-5p and down-regulating ZEB1 Fulltext Access 10 Pages 2018
Cistanche deserticola polysaccharides protects PC12 cells against OGD/RP-induced injury Fulltext Access 10 Pages 2018
Protective effect of the hydroalcoholic extract of Tripodanthus acutifolius in hypercholesterolemic Wistar rats Fulltext Access 10 Pages 2018
Eclalbasaponin I from Aralia elata (Miq.) Seem. reduces oxidative stress-induced neural cell death by autophagy activation Fulltext Access 10 Pages 2018
Haemato-protective influence of dietary fenugreek (Trigonella foenum-graecum L.) seeds is potentiated by onion (Allium cepa L.) in streptozotocin-induced diabetic rats Fulltext Access 10 Pages 2018
CXCL16/ROCK1 signaling pathway exacerbates acute kidney injury induced by ischemia-reperfusion Fulltext Access 10 Pages 2018
Helix aspersa maxima mucus exhibits antimelanogenic and antitumoral effects against melanoma cells Fulltext Access 10 Pages 2018
Cardioprotective effects of total flavonoids from Jinhe Yangxin prescription by activating the PI3K/Akt signaling pathway in myocardial ischemia injury Fulltext Access 10 Pages 2018
MicroRNA-30b promotes lipopolysaccharide-induced inflammatory injury and alleviates autophagy through JNK and NF-κB pathways in HK-2 cells Fulltext Access 10 Pages 2018
Ameliorative effects of bee pollen and date palm pollen on the glycemic state and male sexual dysfunctions in streptozotocin-Induced diabetic wistar rats Fulltext Access 10 Pages 2018
Isoorientin triggers apoptosis of hepatoblastoma by inducing DNA double-strand breaks and suppressing homologous recombination repair Fulltext Access 10 Pages 2018
Genetic ablation of TRPV1 exacerbates pressure overload-induced cardiac hypertrophy Fulltext Access 10 Pages 2018
Rapid screening of toxic glycoalkaloids and micronutrients in edible nightshades (Solanum spp.) Fulltext Access 10 Pages 2018
Moringa oleifera stem extract protect skin keratinocytes against oxidative stress injury by enhancement of antioxidant defense systems and activation of PPARα Fulltext Access 10 Pages 2018
Inhibition of miR-31a-5p decreases inflammation by down-regulating IL-25 expression in human dermal fibroblast cells (CC-2511 cells) under hyperthermic stress via Wnt/β-catenin pathway Fulltext Access 10 Pages 2018
The time-dependent effects of St John's wort on cytochrome P450, uridine diphosphate-glucuronosyltransferase, glutathione S-transferase, and NAD(P)H-quinone oxidoreductase in mice Fulltext Access 10 Pages 2018
Anti-inflammatory effect of cinnamaldehyde and linalool from the leaf essential oil of Cinnamomum osmophloeum Kanehira in endotoxin-induced mice Fulltext Access 10 Pages 2018
The effects of Ficus carica on the activity of enzymes related to metabolic syndrome Fulltext Access 10 Pages 2018
Protective effect of Nelumbo nucifera extracts on beta amyloid protein induced apoptosis in PC12 cells, in vitro model of Alzheimer's disease Fulltext Access 10 Pages 2018
Optimal conditions for cordycepin production in surface liquid-cultured Cordyceps militaris treated with porcine liver extracts for suppression of oral cancer Fulltext Access 10 Pages 2018
Comprehensive analysis of Polygoni Multiflori Radix of different geographical origins using ultra-high-performance liquid chromatography fingerprints and multivariate chemometric methods Fulltext Access 10 Pages 2018
Functional components in Scutellaria barbata D. Don with anti-inflammatory activity on RAW 264.7 cells Fulltext Access 10 Pages 2018
In vitro and in vivo assessment of delivery of hydrophobic molecules and plasmid DNAs with PEO-PPO-PEO polymeric micelles on cornea Fulltext Access 10 Pages 2018
A novel protein from edible fungi Cordyceps militaris that induces apoptosis Fulltext Access 10 Pages 2018
Mulberry Leaf Extracts prevent obesity-induced NAFLD with regulating adipocytokines, inflammation and oxidative stress Fulltext Access 10 Pages 2018
Potential role of leukotriene receptor antagonists in reducing cardiovascular and cerbrovascular risk: A systematic review of human clinical trials and in vivo animal studies Fulltext Access 10 Pages 2018
Immunochemical assay with monoclonal antibodies for detection of staphylococcal enterotoxin H Fulltext Access 10 Pages 2018
Production of antioxidant and ACE-inhibitory peptides from Kluyveromyces marxianus protein hydrolysates: Purification and molecular docking Fulltext Access 10 Pages 2018
Characteristics of fucose-containing polysaccharides from submerged fermentation of Agaricus blazei Murill Fulltext Access 10 Pages 2018
Water-soluble polysaccharides from Ulva intestinalis: Molecular properties, structural elucidation and immunomodulatory activities Fulltext Access 10 Pages 2018
Bioactive polyphenols in kinkéliba tea (Combretum micranthum) and their glucose-lowering activities Fulltext Access 10 Pages 2018
Application of thermal stability difference to remove flammutoxin in fungal immunomodulatory protein, FIP-fve, extract from Flammulina velutipes Fulltext Access 10 Pages 2018
Community-based physical activity as adjunctive smoking cessation treatment: Rationale, design, and baseline data for the Lifestyle Enhancement Program (LEAP) randomized controlled trial Fulltext Access 10 Pages 2018
Evaluating the efficacy of an integrated motivational interviewing and multi-modal exercise intervention for youth with major depression: Healthy Body, Healthy Mind randomised controlled trial protocol Fulltext Access 10 Pages 2018
Patient profiling for success after weight loss surgery (GO Bypass study): An interdisciplinary study protocol Fulltext Access 10 Pages 2018
Comparative effectiveness of family problem-solving therapy (F-PST) for adolescents after traumatic brain injury: Protocol for a randomized, multicenter, clinical trial Fulltext Access 10 Pages 2018
Exercise training as S-Klotho protein stimulator in sedentary healthy adults: Rationale, design, and methodology Fulltext Access 10 Pages 2018
Hinokiflavone induces apoptosis in melanoma cells through the ROS-mitochondrial apoptotic pathway and impairs cell migration and invasion Fulltext Access 10 Pages 2018
LncRNA-NR_033515 promotes proliferation, fibrogenesis and epithelial-to-mesenchymal transition by targeting miR-743b-5p in diabetic nephropathy Fulltext Access 10 Pages 2018
Co-culture of ovarian cancer stem-like cells with macrophages induced SKOV3 cells stemness via IL-8/STAT3 signaling Fulltext Access 10 Pages 2018
Protective effect of Lespedeza cuneata ethanol extract on Bisphenol A-induced testicular dysfunction in vivo and in vitro Fulltext Access 10 Pages 2018
α-Terpineol reduces cancer pain via modulation of oxidative stress and inhibition of iNOS Fulltext Access 10 Pages 2018
Overexpression of STAT1 suppresses angiogenesis under hypoxia by regulating VEGFâA in human glioma cells Fulltext Access 10 Pages 2018
Steroidal alkaloid solanine A from Solanum nigrum Linn. exhibits anti-inflammatory activity in lipopolysaccharide/interferon γ-activated murine macrophages and animal models of inflammation Fulltext Access 10 Pages 2018
Involvement of the NO/sGC/cGMP/K+ channels pathway in vascular relaxation evoked by two non-quinazoline α1-adrenoceptor antagonists Fulltext Access 10 Pages 2018
Evidence of hypoglycemic, lipid-lowering and hepatoprotective effects of the Bixin and Bixin: β-CD inclusion compound in high-fat-fed obese mice Fulltext Access 10 Pages 2018
Standard CD44 modulates YAP1 through a positive feedback loop in hepatocellular carcinoma Fulltext Access 10 Pages 2018
Anti-tumor properties of anthocyanins from Lonicera caerulea 'Beilei' fruit on human hepatocellular carcinoma: In vitro and in vivo study Fulltext Access 10 Pages 2018
Dimethylthiourea ameliorates carbon tetrachloride-induced acute liver injury in ovariectomized mice Fulltext Access 10 Pages 2018
Targeted cancer therapy through 17-DMAG as an Hsp90 inhibitor: Overview and current state of the art Fulltext Access 10 Pages 2018
Polygonum aviculare L. extract reduces fatigue by inhibiting neuroinflammation in restraint-stressed mice Fulltext Access 10 Pages 2018
Effects of Zanthoxylum piperitum ethanol extract on osteoarthritis inflammation and pain Fulltext Access 10 Pages 2018
RGD peptide-modified, paclitaxel prodrug-based, dual-drugs loaded, and redox-sensitive lipid-polymer nanoparticles for the enhanced lung cancer therapy Fulltext Access 10 Pages 2018
ROS mediated ER stress induces Bax-Bak dependent and independent apoptosis in response to Thioridazine Fulltext Access 10 Pages 2018
Qing Gan Zi Shen Tang alleviates adipose tissue dysfunction with up-regulation of SIRT1 in spontaneously hypertensive rat Fulltext Access 10 Pages 2018
Silymarin prevents apoptosis through inhibiting the Bax/caspase-3 expression and suppresses toll like receptor-4 pathway in the SNc of 6-OHDA intoxicated rats Fulltext Access 10 Pages 2018
Polymeric nano-encapsulation of 5-fluorouracil enhances anti-cancer activity and ameliorates side effects in solid Ehrlich Carcinoma-bearing mice Fulltext Access 10 Pages 2018
MiR-92a regulates oral squamous cell carcinoma (OSCC) cell growth by targeting FOXP1 expression Fulltext Access 10 Pages 2018
Melatonin ameliorates bisphenol A-induced perturbations of the prostate gland of adult Wistar rats Fulltext Access 10 Pages 2018
Taxifolin binds with LXR (α & β) to attenuate DMBA-induced mammary carcinogenesis through mTOR/Maf-1/PTEN pathway Fulltext Access 10 Pages 2018