N-3 PUFA diet enrichment prevents amyloid beta-induced depressive-like phenotype Fulltext Access 9 Pages 2018
Common variation in ZNF804A (rs1344706) is not associated with brain morphometry in schizophrenia or healthy participants Fulltext Access 9 Pages 2018
Pharmacological analysis of zebrafish lphn3.1 morphant larvae suggests that saturated dopaminergic signaling could underlie the ADHD-like locomotor hyperactivity Fulltext Access 9 Pages 2018
Applying ketamine to alleviate the PTSD-like effects by regulating the HCN1-related BDNF Fulltext Access 9 Pages 2018
5-HT1B receptor agonist CGS12066 presynaptically inhibits glutamate release in rat hippocampus Fulltext Access 9 Pages 2018
Estradiol-induced enhancement of fear extinction in female rats: The role of NMDA receptor activation Fulltext Access 9 Pages 2018
Significance of A-to-I RNA editing of transcripts modulating pharmacokinetics and pharmacodynamics Fulltext Access 9 Pages 2018
Hormesis as a mechanistic approach to understanding herbal treatments in traditional Chinese medicine Fulltext Access 9 Pages 2018
Two intermediate states of the conformational switch in dual specificity phosphatase 13a Fulltext Access 9 Pages 2018
Transitioning from first- to second-generation biosimilars: An appraisal of regulatory and post-marketing challenges Fulltext Access 9 Pages 2018
Bleeding in advanced CKD patients on antithrombotic medication - A critical appraisal Fulltext Access 9 Pages 2018
Panic-like escape response elicited in mice by exposure to CO2, but not hypoxia Fulltext Access 9 Pages 2018
Molecular modeling study on resistance of WT/D473H SMO to antagonists LDE-225 and LEQ-506 Fulltext Access 9 Pages 2018
Down regulation of pro-inflammatory pathways by tanshinone IIA and cryptotanshinone in a non-genetic mouse model of Alzheimer's disease Fulltext Access 9 Pages 2018
Resveratrol dimer trans-ε-viniferin prevents rotaviral diarrhea in mice by inhibition of the intestinal calcium-activated chloride channel Fulltext Access 9 Pages 2018
Preclinical assessment of utility of M6S for multimodal acute and chronic pain treatment in diabetic neuropathy Fulltext Access 9 Pages 2018
Baicalin attenuates non-alcoholic steatohepatitis by suppressing key regulators of lipid metabolism, inflammation and fibrosis in mice Fulltext Access 9 Pages 2018
Exercise training versus T3 and T4 hormones treatment: The differential benefits of thyroid hormones on the parasympathetic drive of infarcted rats Fulltext Access 9 Pages 2018
Comparative study of the antioxidant properties of monocarbonyl curcumin analogues C66 and B2BrBC in isoproteranol induced cardiac damage Fulltext Access 9 Pages 2018
Effects of electroacupuncture on luteal regression and steroidogenesis in ovarian hyperstimulation syndrome model rat Fulltext Access 9 Pages 2018
Acute and sub acute studies of catechol derivatives from Semecarpus anacardium Fulltext Access 9 Pages 2018
Cryptochrome 1 promotes osteogenic differentiation of human osteoblastic cells via Wnt/β-Catenin signaling Fulltext Access 9 Pages 2018
Roles of the KEAP1-NRF2 system in mammalian skin exposed to UV radiation Fulltext Access 9 Pages 2018
Moracin derivatives from Morus Radix as dual BACE1 and cholinesterase inhibitors with antioxidant and anti-glycation capacities Fulltext Access 9 Pages 2018
Euxanthone suppresses tumor growth and metastasis in colorectal cancer via targeting CIP2A/PP2A pathway Fulltext Access 9 Pages 2018
Oncogene miR-154-5p regulates cellular function and acts as a molecular marker with poor prognosis in renal cell carcinoma Fulltext Access 9 Pages 2018
Extracellular ubiquitin modulates cardiac fibroblast phenotype and function via its interaction with CXCR4 Fulltext Access 9 Pages 2018
Integration of sperm DNA damage assessment into OECD test guidelines for genotoxicity testing using the MutaMouse model Fulltext Access 9 Pages 2018
Safety profile of 40% Garcinol from Garcinia indica in experimental rodents Fulltext Access 9 Pages 2018
Acetonic extract of Vernonia amygdalina (Del.) attenuates Cd-induced liver injury: Potential application in adjuvant heavy metal therapy Fulltext Access 9 Pages 2018
Akt modulation by miR-145 during exercise-induced VSMC phenotypic switching in hypertension Fulltext Access 9 Pages 2018
Interaction of anthraquinones of Cassia occidentalis seeds with DNA and Glutathione Fulltext Access 9 Pages 2018
Pb2Â + modulates ryanodine receptors from the endoplasmic reticulum in rat brain Fulltext Access 9 Pages 2018
The antipsychotics sulpiride induces fatty liver in rats via phosphorylation of insulin receptor substrate-1 at Serine 307-mediated adipose tissue insulin resistance Fulltext Access 9 Pages 2018
Effects of continuous bisphenol A exposure from early gestation on 90â¯day old rat testes function and sperm molecular profiles: A CLARITY-BPA consortium study Fulltext Access 9 Pages 2018
The vanillin derivative 6-bromine-5-hydroxy-4-methoxybenzaldehyde induces aberrant mitotic progression and enhances radio-sensitivity accompanying suppression the expression of PLK1 in esophageal squamous cell carcinoma Fulltext Access 9 Pages 2018
Stabilization of the hypoxia-inducible transcription Factor-1 alpha (HIF-1α) in thiamine deficiency is mediated by pyruvate accumulation Fulltext Access 9 Pages 2018
Therapeutic administration of inhaled INS1009, a treprostinil prodrug formulation, inhibits bleomycin-induced pulmonary fibrosis in rats Fulltext Access 9 Pages 2018
Increased interferon-mediated immunity following in vitro and in vivo Modafinil treatment on peripheral immune cells Fulltext Access 9 Pages 2018
Flavones-bound in benzodiazepine site on GABAA receptor: Concomitant anxiolytic-like and cognitive-enhancing effects produced by Isovitexin and 6-C-glycoside-Diosmetin Fulltext Access 10 Pages 2018
Diazepam fails to alter anxiety-like responses but affects motor function in a white-black test paradigm in larval zebrafish (Danio rerio) Fulltext Access 10 Pages 2018
Chemical composition, traditional and professional use in medicine, application in environmental protection, position in food and cosmetics industries, and biotechnological studies of Nasturtium officinale (watercress) - a review Fulltext Access 10 Pages 2018
Z-505 hydrochloride ameliorates chemotherapy-induced anorexia in rodents via activation of the ghrelin receptor, GHSR1a Fulltext Access 10 Pages 2018
Cordycepin inhibits LPS-induced acute lung injury by inhibiting inflammation and oxidative stress Fulltext Access 10 Pages 2018
LncRNA myocardial infarction-associated transcript (MIAT) contributed to cardiac hypertrophy by regulating TLR4 via miR-93 Fulltext Access 10 Pages 2018
Physicochemical, pharmacokinetic, efficacy and toxicity profiling of a potential nitrofuranyl methyl piperazine derivative IIIM-MCD-211 for oral tuberculosis therapy via in-silico-in-vitro-in-vivo approach Fulltext Access 10 Pages 2018
A new promising simultaneous approach for attenuating type II diabetes mellitus induced neuropathic pain in rats: iNOS inhibition and neuroregeneration Fulltext Access 10 Pages 2018
Synthesis and in vitro characterization of a P2X7 radioligand [123I]TZ6019 and its response to neuroinflammation in a mouse model of Alzheimer disease Fulltext Access 10 Pages 2018
New application of the commercial sweetener rebaudioside a as a hepatoprotective candidate: Induction of the Nrf2 signaling pathway Fulltext Access 10 Pages 2018
JN-2, a C-X-C motif chemokine receptor 3 antagonist, ameliorates arthritis progression in an animal model Fulltext Access 10 Pages 2018
Epigenetic modification of Nrf2 by sulforaphane increases the antioxidative and anti-inflammatory capacity in a cellular model of Alzheimer's disease Fulltext Access 10 Pages 2018
The in vitro pharmacology and non-clinical cardiovascular safety studies of a novel 5-HT4 receptor agonist, DSP-6952 Fulltext Access 10 Pages 2018
Rapid profiling and pharmacokinetic studies of multiple potential bioactive triterpenoids in rat plasma using UPLC/Q-TOF-MS/MS after oral administration of Ilicis Rotundae Cortex extract Fulltext Access 10 Pages 2018
Gαi and Gβγ subunits have opposing effects on dexmedetomidine-induced sedation Fulltext Access 10 Pages 2018
Application of machine learning classification for structural brain MRI in mood disorders: Critical review from a clinical perspective Fulltext Access 10 Pages 2018
The minor histocompatibility antigen 1 (HMHA1)/ArhGAP45 is a RacGAP and a novel regulator of endothelial integrity Fulltext Access 10 Pages 2018
Punishment of alcohol-reinforced responding in alcohol preferring P rats reveals a bimodal population: Implications for models of compulsive drug seeking Fulltext Access 10 Pages 2018
Gene polymorphisms of DISC1 is associated with schizophrenia: Evidence from a meta-analysis Fulltext Access 10 Pages 2018
Serotonergic hallucinogens in the treatment of anxiety and depression in patients suffering from a life-threatening disease: A systematic review Fulltext Access 10 Pages 2018
Eight new triterpenoids with inhibitory activity against HMG-CoA reductase from the medical mushroom Ganoderma leucocontextum collected in Tibetan plateau Fulltext Access 10 Pages 2018
Liuweiwuling tablets attenuate BDL-induced hepatic fibrosis via modulation of TGF-β/Smad and NF-κB signaling pathways Fulltext Access 10 Pages 2018
Protective effect of Danhong Injection combined with Naoxintong Capsule on cerebral ischemia-reperfusion injury in rats Fulltext Access 10 Pages 2018
Safety pharmacology in and for Africa: Establishment of the pre-clinical drug development platform Fulltext Access 10 Pages 2018
Comparison of one- and three-lead ECG to measure cardiac intervals and differentiate drug-induced multi-channel block Fulltext Access 10 Pages 2018
Anti-proliferative and pro-apoptotic effects of Uncaria tomentosa aqueous extract in squamous carcinoma cells Fulltext Access 10 Pages 2018
Leishmanicidal activity of the root bark of Erythrophleum Ivorense (Fabaceae) and identification of some of its compounds by ultra-performance liquid chromatography quadrupole time of flight mass spectrometry (UPLC-QTOF-MS/MS) Fulltext Access 10 Pages 2018
Isomeric flavonoid aglycones derived from Epimedii Folium exerted different intensities in anti-osteoporosis through OPG/RANKL protein targets Fulltext Access 10 Pages 2018
Metabolic profiles revealed anti-ischemia-reperfusion injury of Yangxinshi tablet in Rats Fulltext Access 10 Pages 2018
A proanthocyanidin-rich extract from Cassia abbreviata exhibits antioxidant and hepatoprotective activities in vivo Fulltext Access 10 Pages 2018
Propofol induced diverse and subtype-specific translocation of PKC families Fulltext Access 10 Pages 2018
Dimethyl fumarate ameliorates chemotherapy agent-induced neurotoxicity in vitro Fulltext Access 10 Pages 2018
Up-regulation of microRNA-93 inhibits TGF-β1-induced EMT and renal fibrogenesis by down-regulation of Orai1 Fulltext Access 10 Pages 2018
Systems pharmacology dissection of the anti-stroke mechanism for the Chinese traditional medicine Xing-Nao-Jing Fulltext Access 10 Pages 2018
Ezrin as a complementary marker in ocular toxicity assessment using a three-dimensional reconstructed human corneal-like epithelium model, EpiOcular⢠Fulltext Access 10 Pages 2018
Establishment of a novel microscale thermophoresis ligand-binding assay for characterization of SLC solute carriers using oligopeptide transporter PepT1 (SLC15 family) as a model system Fulltext Access 10 Pages 2018
Anti-ulcer and anti-Helicobacter pylori potentials of the ethyl acetate fraction of Physalis alkekengi L. var. franchetii (Solanaceae) in rodent Fulltext Access 10 Pages 2018
Ginseng polysaccharides enhanced ginsenoside Rb1 and microbial metabolites exposure through enhancing intestinal absorption and affecting gut microbial metabolism Fulltext Access 10 Pages 2018
Anti-inflammatory and immune response regulation of Si-Ni-San in 2,4-dinitrochlorobenzene-induced atopic dermatitis-like skin dysfunction Fulltext Access 10 Pages 2018
A 13-week subchronic toxicity study of an Eriobotrya japonica leaf extract in rats Fulltext Access 10 Pages 2018
Implementation of a pharmacist-led pharmacogenomics service for the Program of All-Inclusive Care for the Elderly (PHARM-GENOME-PACE) Fulltext Access 10 Pages 2018
Comparison of two training methods in community pharmacy: Project VACCINATE Fulltext Access 10 Pages 2018
Protective effect of ethyl acetate fraction of Drynaria quercifolia against CCl4 induced rat liver fibrosis via Nrf2/ARE and NFκB signalling pathway Fulltext Access 10 Pages 2018
1, 25-dihydroxyvitamin D3 downregulates cytotoxic effector response in pulmonary tuberculosis Fulltext Access 10 Pages 2018
The flavonoid kurarinone inhibits clinical progression of EAE through inhibiting Th1 and Th17 cell differentiation and proliferation Fulltext Access 10 Pages 2018
Sauchinone inhibits IL-1β induced catabolism and hypertrophy in mouse chondrocytes to attenuate osteoarthritis via Nrf2/HO-1 and NF-κB pathways Fulltext Access 10 Pages 2018
Therapeutic effects of 5,2â²-dibromo-2,4â²,5â²-trihydroxydiphenylmethanone (LM49) in an experimental rat model of acute pyelonephritis by immunomodulation and anti-inflammation Fulltext Access 10 Pages 2018
Genistein reduces proliferation of EP3-expressing melanoma cells through inhibition of PGE2-induced IL-8 expression Fulltext Access 10 Pages 2018
A systematic investigation on animal models of cyclosporine A combined with Escherichia coli to simulate the immunosuppressive status of sepsis patients before onset Fulltext Access 10 Pages 2018
Influenza virus-like particles composed of conserved influenza proteins and GPI-anchored CCL28/GM-CSF fusion proteins enhance protective immunity against homologous and heterologous viruses Fulltext Access 10 Pages 2018
Microvesicles packaging IL-1β and TNF-α enhance lung inflammatory response to mechanical ventilation in part by induction of cofilin signaling Fulltext Access 10 Pages 2018
Isolation, modification and cytotoxic evaluation of stilbenoids from Acanthopanax leucorrhizus Fulltext Access 10 Pages 2018
7α,8α-Epoxynagilactones and their glucosides from the twigs of Podocarpus nagi: Isolation, structures, and cytotoxic activities Fulltext Access 10 Pages 2018
Jatrophane diterpenoids from Euphorbia helioscopia and their lipid-lowering activities Fulltext Access 10 Pages 2018
Heterocyclic pyrrolizinone and indolizinones derived from natural lactam as potential antifungal agents Fulltext Access 10 Pages 2018
Systemic inflammation in asocial BTBR T+ tf/J mice predisposes them to increased psoriatic inflammation Fulltext Access 10 Pages 2018