Neurotensin speeds inhibition of dopamine neurons through temporal modulation of GABAA and GABAB receptor-mediated synaptic input Fulltext Access 10 Pages 2018
Effect of electroconvulsive therapy on neural response to affective pictures: A randomized, sham-controlled fMRI study Fulltext Access 10 Pages 2018
Network pharmacology-based analysis of Chinese herbal Naodesheng formula for application to Alzheimer's disease Fulltext Access 10 Pages 2018
Cucurbitacin B suppresses metastasis mediated by reactive oxygen species (ROS) via focal adhesion kinase (FAK) in breast cancer MDA-MB-231 cells Fulltext Access 10 Pages 2018
Salvianolic acid A attenuates ischemia reperfusion induced rat brain damage by protecting the blood brain barrier through MMP-9 inhibition and anti-inflammation Fulltext Access 10 Pages 2018
1H NMR-based metabolomics approach to investigating the renal protective effects of Genipin in diabetic rats Fulltext Access 10 Pages 2018
Gastrodin reduces IL-1β-induced apoptosis, inflammation, and matrix catabolism in osteoarthritis chondrocytes and attenuates rat cartilage degeneration in vivo Fulltext Access 10 Pages 2018
Comprehensive analysis and experimental verification of LINC01314 as a tumor suppressor in hepatoblastoma Fulltext Access 10 Pages 2018
Chemoprotective role of ethanol extract of Urtica urens L. against the toxicity of imidacloprid on endocrine disruption and ovarian morphometric in female rats, GC/MS analysis Fulltext Access 10 Pages 2018
Alpha, 2'-dihydroxy-4,4'-dimethoxydihydrochalcone inhibits cell proliferation, invasion, and migration in gastric cancer in part via autophagy Fulltext Access 10 Pages 2018
Isoflurane post-conditioning down-regulates expression of aquaporin 4 in rats with cerebral ischemia/reperfusion injury and is possibly related to bone morphogenetic protein 4/Smad1/5/8 signaling pathway Fulltext Access 10 Pages 2018
Acanthopanax senticosus reduces brain injury in mice exposed to low linear energy transfer radiation Fulltext Access 10 Pages 2018
Effect of cytochrome CYP2C19 metabolizing activity on antidepressant response and side effects: Meta-analysis of data from genome-wide association studies Fulltext Access 10 Pages 2018
Liraglutide ameliorates cognitive decline by promoting autophagy via the AMP-activated protein kinase/mammalian target of rapamycin pathway in a streptozotocin-induced mouse model of diabetes Fulltext Access 10 Pages 2018
Neurogranin in the nucleus accumbens regulates NMDA receptor tolerance and motivation for ethanol seeking Fulltext Access 10 Pages 2018
Cannabinoids induce apathetic and impulsive patterns of choice through CB1 receptors and TRPV1 channels Fulltext Access 10 Pages 2018
Neurocognitive dysfunction following repeated binge-like self-administration of the synthetic cathinone 3,4-methylenedioxypyrovalerone (MDPV) Fulltext Access 10 Pages 2018
Physiological roles of CNS muscarinic receptors gained from knockout mice Fulltext Access 10 Pages 2018
Pharmacological inhibition of Receptor Protein Tyrosine Phosphatase β/ζ (PTPRZ1) modulates behavioral responses to ethanol Fulltext Access 10 Pages 2018
The psychostimulant (±)-cis-4,4â²-dimethylaminorex (4,4â²-DMAR) interacts with human plasmalemmal and vesicular monoamine transporters Fulltext Access 10 Pages 2018
Regulation of glutamate transporter 1 (GLT-1) gene expression by cocaine self-administration and withdrawal Fulltext Access 10 Pages 2018
Biorelevant Media Slows the Solution-Mediated Phase Transformation of Amorphous Spironolactone Fulltext Access 10 Pages 2018
Drug Solubilization by Means of a Surface-Modified Edible Biopolymer Enabled by Hot Melt Extrusion Fulltext Access 10 Pages 2018
Moringa oleifera and their phytonanoparticles: Potential antiproliferative agents against cancer Fulltext Access 10 Pages 2018
Seasonality-resilient individuals downregulate their cerebral 5-HT transporter binding in winter - A longitudinal combined 11C-DASB and 11C-SB207145 PET study Fulltext Access 10 Pages 2018
Melatonin and its metabolite N1-acetyl-N2-formyl-5-methoxykynuramine (afmk) enhance chemosensitivity to gemcitabine in pancreatic carcinoma cells (PANC-1) Fulltext Access 10 Pages 2018
Chronic antidepressant-like effect of EMD386088, a partial 5-HT6 receptor agonist, in olfactory bulbectomy model may be connected with BDNF and/or CREB signalling pathway Fulltext Access 10 Pages 2018
Adolescents douloureux chroniques déscolarisés : expérience de l'hospitalisation à temps plein en soins/études Fulltext Access 10 Pages 2018
Saikosaponin D from Radix Bupleuri suppresses triple-negative breast cancer cell growth by targeting β-catenin signaling Fulltext Access 10 Pages 2018
Transcription factor 7-like 2 controls matrix degradation through nuclear factor κB signaling and is repressed by microRNA-155 in nucleus pulposus cells Fulltext Access 10 Pages 2018
miR-326 functions as a tumor suppressor in human prostatic carcinoma by targeting Mucin1 Fulltext Access 10 Pages 2018
Lipocalin-2 protects against renal ischemia/reperfusion injury in mice through autophagy activation mediated by HIF1α and NF-κb crosstalk Fulltext Access 10 Pages 2018
The influence of gut microbiota dysbiosis to the efficacy of 5-Fluorouracil treatment on colorectal cancer Fulltext Access 10 Pages 2018
Sedative-hypnotic like effect of 5-methoxyflavone in mice and investigation on possible mechanisms by in vivo and in silico methods Fulltext Access 10 Pages 2018
Dual gene deficient models of ApcMin/+ mouse in assessing molecular mechanisms of intestinal carcinogenesis Fulltext Access 10 Pages 2018
Identification and validation of midbrain Kcnq4 regulation of heavy alcohol consumption in rodents Fulltext Access 10 Pages 2018
LncRNA DBH-AS1 facilitates the tumorigenesis of hepatocellular carcinoma by targeting miR-138 via FAK/Src/ERK pathway Fulltext Access 10 Pages 2018
Targeting NLRP3 inflammasome via acetylsalicylic acid: Role in suppressing hepatic dysfunction and insulin resistance induced by atorvastatin in naïve versus alcoholic liver in rats Fulltext Access 10 Pages 2018
Premna integrifolia ameliorates cyclophosphamide-induced hepatotoxicity by modulation of oxidative stress and apoptosis Fulltext Access 10 Pages 2018
Polyphenolic composition, enzyme inhibitory effects ex-vivo and in-vivo studies on two Brassicaceae of north-central Italy Fulltext Access 10 Pages 2018
The role of XIAP in resistance to TNF-related apoptosis-inducing ligand (TRAIL) in Leukemia Fulltext Access 10 Pages 2018
Neonatal exposure to sevoflurane caused cognitive deficits by dysregulating SK2 channels and GluA2-lacking AMPA receptors in juvenile rat hippocampus Fulltext Access 10 Pages 2018
Neuropharmacology genetic deletion of the dopamine D3 receptor increases vulnerability to heroin in mice Fulltext Access 10 Pages 2018
12-week double-blind randomized multicenter study of efficacy and safety of agomelatine (25-50â¯mg/day) versus escitalopram (10-20â¯mg/day) in out-patients with severe generalized anxiety disorder Fulltext Access 10 Pages 2018
Authentic compound-free strategy for simultaneous determination of primary coumarins in Peucedani Radix using offline high performance liquid chromatography-nuclear magnetic resonance spectroscopy-tandem mass spectrometry Fulltext Access 10 Pages 2018
Mechanisms of RhoA inactivation and CDC42 and Rac1 activation during zebrafish optic nerve regeneration Fulltext Access 10 Pages 2018
Expression and regulation of CYP17A1 and 3β-hydroxysteroid dehydrogenase in cells of the nervous system: Potential effects of vitamin D on brain steroidogenesis Fulltext Access 10 Pages 2018
Fisetin alleviates oxidative stress after traumatic brain injury via the Nrf2-ARE pathway Fulltext Access 10 Pages 2018
Phosphatidylethanolamine-binding protein 1 protects CA1 neurons against ischemic damage via ERK-CREB signaling in Mongolian gerbils Fulltext Access 10 Pages 2018
RESP18 deficiency has protective effects in dopaminergic neurons in an MPTP mouse model of Parkinson's disease Fulltext Access 10 Pages 2018
Endogenous acetylcholine regulates neuronal and astrocytic vascular endothelial growth factor expression levels via different acetylcholine receptor mechanisms Fulltext Access 10 Pages 2018
Riparin II ameliorates corticosterone-induced depressive-like behavior in mice: Role of antioxidant and neurotrophic mechanisms Fulltext Access 10 Pages 2018
Automated techniques in pKa determination: Low, medium and high-throughput screening methods Fulltext Access 10 Pages 2018
HDL functionality in familial hypercholesterolemia: effects of treatment modalities and pharmacological interventions Fulltext Access 10 Pages 2018
CHEMGENIE: integration of chemogenomics data for applications in chemical biology Fulltext Access 10 Pages 2018
Biochemical marker discovery, testing and evaluation for facilitating OA drug discovery and development Fulltext Access 10 Pages 2018
Thymoquinone-based nanotechnology for cancer therapy: promises and challenges Fulltext Access 10 Pages 2018
Cellular Pharmacokinetic Model-Based Analysis of Genistein, Glyceollin, and MK-571 Effects on 5 (and 6)-Carboxy-2â²,7â²-Dichloroflourescein Disposition in Caco-2 Cells Fulltext Access 10 Pages 2018
N-acylethanolamine hydrolyzing acid amidase inhibition: tools and potential therapeutic opportunities Fulltext Access 10 Pages 2018
Arvanil, olvanil, AM 1172 and LY 2183240 (various cannabinoid CB1 receptor agonists) increase the threshold for maximal electroshock-induced seizures in mice Fulltext Access 10 Pages 2018
Estrogenic effects following larval exposure to the putative anti-estrogen, fulvestrant, in the fathead minnow (Pimephales promelas) Fulltext Access 10 Pages 2018
Characterization of basal gene expression trends over a diurnal cycle in Xiphophorus maculatus skin, brain and liver Fulltext Access 10 Pages 2018
Insights on the age dependent neurodegeneration induced by Monocrotophos, (an organophosphorous insecticide) in Caenorhabditis elegans fed high glucose: Evidence in wild and transgenic strains Fulltext Access 10 Pages 2018
A multi-centre, randomised, double-blind, placebo-controlled clinical trial of methylphenidate in the initial treatment of acute mania (MEMAP study) Fulltext Access 10 Pages 2018
Adjunctive azapirone for schizophrenia: A meta-analysis of randomized, double-blind, placebo-controlled trials Fulltext Access 10 Pages 2018
Nitric oxide-cGMP-PKG signaling in the bed nucleus of the stria terminalis modulates the cardiovascular responses to stress in male rats Fulltext Access 10 Pages 2018
The vagus nerve modulates BDNF expression and neurogenesis in the hippocampus Fulltext Access 10 Pages 2018
Functional mechanism of ASP5736, a selective serotonin 5-HT5A receptor antagonist with potential utility for the treatment of cognitive dysfunction in schizophrenia Fulltext Access 10 Pages 2018
Increased methylation at an unexplored glucocorticoid responsive element within exon 1D of NR3C1 gene is related to anxious-depressive disorders and decreased hippocampal connectivity Fulltext Access 10 Pages 2018
Psilocybin modulates functional connectivity of the amygdala during emotional face discrimination Fulltext Access 10 Pages 2018
Spectrophotometric analysis of two eye preparations, vial and drops, containing ketorolac tromethamine and phenylephrine hydrochloride binary mixture and their ternary mixture with chlorphenirmaine maleate Fulltext Access 10 Pages 2018
In Vitro-In Vivo Evaluation of an Oral Ghost Drug Delivery Device for the Delivery of Salmon Calcitonin Fulltext Access 10 Pages 2018
Freeze-Drying From Organic Cosolvent Systems, Part 1: Thermal Analysis of Cosolvent-Based Placebo Formulations in the Frozen State Fulltext Access 10 Pages 2018
D-Optimal Design in the Development of Rheologically Improved In Situ Forming Ophthalmic Gel Fulltext Access 10 Pages 2018
Effect of 2 Emulsion-Based Adjuvants on the Structure and Thermal Stability of Staphylococcus aureus Alpha-Toxin Fulltext Access 10 Pages 2018
Moisture-Induced Amorphous Phase Separation of Amorphous Solid Dispersions: Molecular Mechanism, Microstructure, and Its Impact on Dissolution Performance Fulltext Access 10 Pages 2018
Activation of an unconventional meroterpenoid gene cluster in Neosartorya glabra leads to the production of new berkeleyacetals Fulltext Access 10 Pages 2018
Impact of Glycosylation on the Local Backbone Flexibility of Well-Defined IgG1-Fc Glycoforms Using Hydrogen Exchange-Mass Spectrometry Fulltext Access 10 Pages 2018
Enhanced glioma-targeting and stability of LGICP peptide coupled with stabilized peptide DA7R Fulltext Access 10 Pages 2018
Surface modification of PGP for a neutrophil-nanoparticle co-vehicle to enhance the anti-depressant effect of baicalein Fulltext Access 10 Pages 2018
Leukocyte-derived biomimetic nanoparticulate drug delivery systems for cancer therapy Fulltext Access 10 Pages 2018
Antihyperuricemic effect of mangiferin aglycon derivative J99745 by inhibiting xanthine oxidase activity and urate transporter 1 expression in mice Fulltext Access 10 Pages 2018
Correlation analysis between the chemical contents and bioactivity for the quality control of Alismatis Rhizoma Fulltext Access 10 Pages 2018
Beneficial effects of Houttuynia cordata polysaccharides on “two-hit” acute lung injury and endotoxic fever in rats associated with anti-complementary activities Fulltext Access 10 Pages 2018
1,25-Dihydroxyvitamin D3 protects obese rats from metabolic syndrome via promoting regulatory T cell-mediated resolution of inflammation Fulltext Access 10 Pages 2018
Biomonitoring for traditional herbal medicinal products using DNA metabarcoding and single molecule, real-time sequencing Fulltext Access 10 Pages 2018
STEP inhibition reverses behavioral, electrophysiologic, and synaptic abnormalities in Fmr1 KO mice Fulltext Access 11 Pages 2018
Identification by virtual screening and functional characterisation of novel positive and negative allosteric modulators of the α7 nicotinic acetylcholine receptor Fulltext Access 11 Pages 2018
Activation of adenosine A2A or A2B receptors causes hypothermia in mice Fulltext Access 11 Pages 2018
Dysregulation and restoration of homeostatic network plasticity in fragile X syndrome mice Fulltext Access 11 Pages 2018
Behavioral and cellular dopamine D1 and D3 receptor-mediated synergy: Implications for L-DOPA-induced dyskinesia Fulltext Access 11 Pages 2018
Dopamine depletion shifts behavior from activity based reinforcers to more sedentary ones and adenosine receptor antagonism reverses that shift: Relation to ventral striatum DARPP32 phosphorylation patterns Fulltext Access 11 Pages 2018
Activation and blockade of basolateral amygdala 5-HT6 receptor produce anxiolytic-like behaviors in an experimental model of Parkinson's disease Fulltext Access 11 Pages 2018
GABAB receptor subtypes differentially regulate thalamic spindle oscillations Fulltext Access 11 Pages 2018
Dynamic changes in hippocampal microglia contribute to depressive-like behavior induced by early social isolation Fulltext Access 11 Pages 2018