Doxorubicin triggers bioenergetic failure and p53 activation in mouse stem cell-derived cardiomyocytes Fulltext Access 36 Pages 2018
Nimodipine attenuates tau phosphorylation at Ser396 via miR-132/GSK-3β pathway in chronic cerebral hypoperfusion rats Fulltext Access 36 Pages 2018
Osteoprotective effects of salidroside in ovariectomized mice and diabetic mice Fulltext Access 36 Pages 2018
LC-MS guided isolation of diterpenoids from Sapium insigne with α-glucosidase inhibitory activities Fulltext Access 36 Pages 2018
Ginger (Zingiber officinale Roscoe) for the treatment and prevention of necrotizing enterocolitis Fulltext Access 36 Pages 2018
Scientific rationale for traditional use of plants to treat tuberculosis in the eastern region of the OR Tambo district, South Africa Fulltext Access 36 Pages 2018
Resveratrol supports and alpha-naphthoflavone disrupts growth of human ovarian follicles in an in vitro tissue culture model Fulltext Access 36 Pages 2018
Anti-quorum sensing activity, toxicity in zebrafish (Danio rerio) embryos and phytochemical characterization of Trapa natans leaf extracts Fulltext Access 36 Pages 2018
Disruption of liver development and coagulation pathway by ochratoxin A in embryonic zebrafish Fulltext Access 36 Pages 2018
Curcumin plays neuroprotective roles against traumatic brain injury partly via Nrf2 signaling Fulltext Access 36 Pages 2018
Chloroform fraction of Foeniculum vulgare induced ROS mediated, mitochondria-caspase-dependent apoptotic pathway in MCF-7, human breast cancer cell line Fulltext Access 36 Pages 2018
Gastroprotective effect of ethanol extracts of cladodes and roots of Pilosocereus gounellei (A. Weber ex K. Schum.) Bly. Ex Rowl (Cactaceae) on experimental ulcer models Fulltext Access 36 Pages 2018
TAT-mediated intracellular delivery of carboxypeptidase G2 protects against methotrexate-induced cell death in HepG2 cells Fulltext Access 36 Pages 2018
The hidden mechanism beyond ginger (Zingiber officinale Rosc.) potent in vivo and in vitro anti-inflammatory activity Fulltext Access 36 Pages 2018
Leptospermum flavescens Sm. protect pancreatic β cell function from streptozotocin involving apoptosis and autophagy signaling pathway in in vitro and in vivo case study Fulltext Access 36 Pages 2018
TRAIL attenuates sulforaphane-mediated Nrf2 and sustains ROS generation, leading to apoptosis of TRAIL-resistant human bladder cancer cells Fulltext Access 36 Pages 2018
Caffeic acid prevents UVB radiation induced photocarcinogenesis through regulation of PTEN signaling in human dermal fibroblasts and mouse skin Fulltext Access 36 Pages 2018
RNA sequence analysis of inducible pluripotent stem cell-derived cardiomyocytes reveals altered expression of DNA damage and cell cycle genes in response to doxorubicin Fulltext Access 36 Pages 2018
RING finger protein 10 prevents neointimal hyperplasia by promoting apoptosis in vitro and in vivo Fulltext Access 36 Pages 2018
Pharmacodynamics, pharmacokinetics and safety of revefenacin (TD-4208), a long-acting muscarinic antagonist, in patients with chronic obstructive pulmonary disease (COPD): Results of two randomized, double-blind, phase 2 studies Fulltext Access 36 Pages 2018
Overexpressed miR-145 inhibits osteoclastogenesis in RANKL-induced bone marrow-derived macrophages and ovariectomized mice by regulation of Smad3 Fulltext Access 36 Pages 2018
Isoniazid induces apoptosis: Role of oxidative stress and inhibition of nuclear translocation of nuclear factor (erythroid-derived 2)-like 2 (Nrf2) Fulltext Access 36 Pages 2018
Personality measures after gamma ventral capsulotomy in intractable OCD Fulltext Access 36 Pages 2018
Targeting BDNF modulation by plant glycosides as a novel therapeutic strategy in the treatment of depression Fulltext Access 36 Pages 2018
Diagnostic accuracy of NUDT15 gene variants for thiopurine-induced leukopenia: a systematic review and meta-analysis Fulltext Access 36 Pages 2018
Repeated methamphetamine and modafinil induce differential cognitive effects and specific histone acetylation and DNA methylation profiles in the mouse medial prefrontal cortex Fulltext Access 36 Pages 2018
Structure-activity relationships of HDAC8 inhibitors: Non-hydroxamates as anticancer agents Fulltext Access 36 Pages 2018
Efferocytosis in atherosclerotic lesions: Malfunctioning regulatory pathways and control mechanisms Fulltext Access 36 Pages 2018
Secoisolariciresinol diglucoside inhibits adipogenesis through the AMPK pathway Fulltext Access 36 Pages 2018
Sex difference in GPER expression does not change vascular relaxation or reactive oxygen species generation in rat mesenteric resistance arteries Fulltext Access 36 Pages 2018
Protective effect of dioscin against intestinal ischemia/reperfusion injury via adjusting miR-351-5p-mediated oxidative stress Fulltext Access 36 Pages 2018
Salvianolic acid B as an anti-emphysema agent II: In vivo reversal activities in two rat models of emphysema Fulltext Access 36 Pages 2018
Identification of 5-hydroxymethylfurfural in cigarette smoke extract as a new substrate metabolically activated by human cytochrome P450 2A13 Fulltext Access 36 Pages 2018
Alpha pinene modulates UVA-induced oxidative stress, DNA damage and apoptosis in human skin epidermal keratinocytes Fulltext Access 36 Pages 2018
Effective suppression of donor specific antibody production by Cathepsin S inhibitors in a mouse transplantation model Fulltext Access 36 Pages 2018
Protective role of glucocorticosteroid prior to endotoxin exposure in cultured neonatal type II alveolar epithelial cells Fulltext Access 36 Pages 2018
S1P promotes migration, differentiation and immune regulatory activity in amniotic-fluid-derived stem cells Fulltext Access 36 Pages 2018
Black bean peptides inhibit glucose uptake in Caco-2 adenocarcinoma cells by blocking the expression and translocation pathway of glucose transporters Fulltext Access 36 Pages 2018
Deoxynucleosides with benzimidazoles as aglycone moiety are potent anticancer agents Fulltext Access 36 Pages 2018
Levetiracetam mitigates lipopolysaccharide-induced JAK2/STAT3 and TLR4/MAPK signaling pathways activation in a rat model of adjuvant- induced arthritis Fulltext Access 36 Pages 2018
A major component of vitamin E, α-tocopherol inhibits the anti-tumor activity of crizotinib against cells transformed by EML4-ALK Fulltext Access 36 Pages 2018
Occurrence of Aflatoxin M1 in cow milk in El Salvador: Results from a two-year survey Fulltext Access 36 Pages 2018
Phosphodiesterase-3 inhibitor cilostazol reverses endothelial dysfunction with ageing in rat mesenteric resistance arteries Fulltext Access 36 Pages 2018
Effect of a spacer on total systemic and lung bioavailability in healthy volunteers and in vitro performance of the Symbicort® (budesonide/formoterol) pressurized metered dose inhaler Fulltext Access 37 Pages 2018
Hyperglycemia elicits anxiety-like behaviors in zebrafish: Protective role of dietary diphenyl diselenide Fulltext Access 37 Pages 2018
Intranasal delivery of a novel acetylcholinesterase inhibitor HLS-3 for treatment of Alzheimer's disease Fulltext Access 37 Pages 2018
The antipsychotic agent clozapine induces autophagy via the AMPK-ULK1-Beclin1 signaling pathway in the rat frontal cortex Fulltext Access 37 Pages 2018
A proton MR spectroscopy study of the thalamus in twins with autism spectrum disorder Fulltext Access 37 Pages 2018
14-Deoxy-11,12-didehydroandrographolide suppresses adipogenesis of 3 T3-L1 preadipocytes by inhibiting CCAAT/enhancer-binding protein β activation and AMPK-mediated mitotic clonal expansion Fulltext Access 37 Pages 2018
Gliclazide, a KATP channel blocker, inhibits vascular smooth muscle cell proliferation through the CaMKKβ-AMPK pathway Fulltext Access 37 Pages 2018
Role of Mcl-1 in regulation of cell death in human induced pluripotent stem cell-derived cardiomyocytes in vitro Fulltext Access 37 Pages 2018
Immunometabolic regulation by triterpenes of Eucalyptus tereticornis in adipose tissue cell line models Fulltext Access 37 Pages 2018
ADRB2 gene polymorphism and emphysema heterogeneity can modulate bronchodilator response in patients with emphysema Fulltext Access 37 Pages 2018
Novel formononetin-7-sal ester ameliorates pulmonary fibrosis via MEF2c signaling pathway Fulltext Access 37 Pages 2018
Modulation of tetrodotoxin-resistant Na+ channels by amitriptyline in dural afferent neurons Fulltext Access 37 Pages 2018
Paeoniflorin regulates GALNT2-ANGPTL3-LPL pathway to attenuate dyslipidemia in mice Fulltext Access 37 Pages 2018
3D human brain cell models: New frontiers in disease understanding and drug discovery for neurodegenerative diseases Fulltext Access 37 Pages 2018
Roles of CSGalNAcT1, a key enzyme in regulation of CS synthesis, in neuronal regeneration and plasticity Fulltext Access 37 Pages 2018
Repurposing potential of 1st generation H1-specific antihistamines as anti-filovirus therapeutics Fulltext Access 37 Pages 2018
Efficacy of constant long-term delivery of YM-58483 for the treatment of rheumatoid arthritis Fulltext Access 37 Pages 2018
Interferon-stimulated gene 15 promotes cholesterol efflux by activating autophagy via the miR-17-5p/Beclin-1 pathway in THP-1 macrophage-derived foam cells Fulltext Access 37 Pages 2018
Protein kinases are involved in the cardioprotective effects activated by platelet glycoprotein IIb/IIIa inhibitor tirofiban at reperfusion in rats in vivo Fulltext Access 37 Pages 2018
Tanshinone IIA suppresses FcεRI-mediated mast cell signaling and anaphylaxis by activation of the Sirt1/LKB1/AMPK pathway Fulltext Access 37 Pages 2018
Role of tenofovir alafenamide (TAF) in the treatment and prophylaxis of HIV and HBV infections Fulltext Access 37 Pages 2018
A small-molecule inhibitor of HIV-1 Rev function detected by a diversity screen based on RRE-Rev interference Fulltext Access 37 Pages 2018
Deciphering the potential of baicalin as an antiviral agent for Chikungunya virus infection Fulltext Access 37 Pages 2018
Genistein inhibits African swine fever virus replication in vitro by disrupting viral DNA synthesis Fulltext Access 37 Pages 2018
Antiallodynic and antihyperalgesic activity of new 3,3-diphenyl-propionamides with anticonvulsant activity in models of pain in mice Fulltext Access 37 Pages 2018
Auraptene regulates Th1/Th2/TReg balances, NF-κB nuclear localization and nitric oxide production in normal and Th2 provoked situations in human isolated lymphocytes Fulltext Access 37 Pages 2018
Novel mathematic models for quantitative transitivity of quality-markers in extraction process of the Buyanghuanwu decoction Fulltext Access 37 Pages 2018
Ovicidal effect of essential oils from Zingiberaceae plants and Eucalytus globulus on eggs of head lice, Pediculus humanus capitis De Geer Fulltext Access 37 Pages 2018
Mesoporous Pravastatin Solid Dispersion Granules Incorporable Into Orally Disintegrating Tablets Fulltext Access 37 Pages 2018
Mechanism and Structural Factors of Lipid and Surfactant in the Formation of Self-Emulsified Nanoemulsion Fulltext Access 37 Pages 2018
Under stressful conditions activation of the ionotropic P2X7 receptor differentially regulates GABA and glutamate release from nerve terminals of the rat cerebral cortex Fulltext Access 37 Pages 2018
Astrocytic γ-aminobutyric acid (GABA) transporters mediate guanidinoacetate transport in rat brain Fulltext Access 37 Pages 2018
Human dihydrolipoamide dehydrogenase (E3) deficiency: Novel insights into the structural basis and molecular pathomechanism Fulltext Access 37 Pages 2018
Anti-allergic effects of the ethanol extract of Syzygium formosum (Wall.) Masam leaves and its immunoregulatory mechanisms Fulltext Access 37 Pages 2018
Anti-inflammatory effect of ATB-352, a H2S âreleasing ketoprofen derivative, on lipopolysaccharide-induced periodontitis in rats Fulltext Access 37 Pages 2018
Regulator of calcineurin 1 modulates vascular contractility and stiffness through the upregulation of COX-2-derived prostanoids Fulltext Access 37 Pages 2018
Maternal treatment with a placental-targeted antioxidant (MitoQ) impacts offspring cardiovascular function in a rat model of prenatal hypoxia Fulltext Access 37 Pages 2018
Effects of dehydroepiandrosterone on the ovarian reserve and pregnancy outcomes in perimenopausal rats (DHEA and fertility in perimenopausal rats) Fulltext Access 37 Pages 2018
Cell- and stage-specific localization of galectin-3, a β-galactoside-binding lectin, in a mouse model of experimental autoimmune encephalomyelitis Fulltext Access 37 Pages 2018
Adenosine A2A receptor blockade attenuates spatial memory deficit and extent of demyelination areas in lyolecithin-induced demyelination model Fulltext Access 37 Pages 2018
Melatonin inhibits osteosarcoma stem cells by suppressing SOX9-mediated signaling Fulltext Access 37 Pages 2018
C-type natriuretic peptide (CNP) in endothelial cells attenuates hepatic fibrosis and inflammation in non-alcoholic steatohepatitis Fulltext Access 37 Pages 2018
DACT2 Epigenetic Stimulator Exerts Dual Efficacy for Colorectal Cancer Prevention and Treatment Fulltext Access 37 Pages 2018
Gynura divaricata attenuates tumor growth and tumor relapse after cisplatin therapy in HCC xenograft model through suppression of cancer stem cell growth and Wnt/β-catenin signalling Fulltext Access 37 Pages 2018
Assessment of the anti-snakebite properties of extracts of Aniba fragrans Ducke (Lauraceae) used in folk medicine as complementary treatment in cases of envenomation by Bothrops atrox Fulltext Access 37 Pages 2018
Standardized fraction of Xylocarpus moluccensis fruits improve vascular relaxation and plaque stability in dyslipidemic models of atherosclerosis Fulltext Access 37 Pages 2018
Eugenia brasiliensis leaves extract attenuates visceral and somatic inflammatory pain in mice Fulltext Access 37 Pages 2018
Acetone fraction from Sechium edule (Jacq.) S.w. edible roots exhibits anti-endothelial dysfunction activity Fulltext Access 37 Pages 2018
Achyranthis bidentatae radix enhanced articular distribution and anti-inflammatory effect of berberine in Sanmiao Wan using an acute gouty arthritis rat model Fulltext Access 37 Pages 2018
Gastro-protective, therapeutic and anti-inflammatory activities of Pistacia lentiscus L. fatty oil against ethanol-induced gastric ulcers in rats Fulltext Access 37 Pages 2018
17β-estradiol suppresses carboxylesterases by activating c-Jun/AP-1 pathway in primary human and mouse hepatocytes Fulltext Access 37 Pages 2018