|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|5131454||1491309||2017||4 صفحه PDF||سفارش دهید||دانلود کنید|
Gas chromatography mass spectrometry has been the lynchpin of clinical assessment of steroid profiles for â¼3 decades. The improvements in assay performance offered by tandem mass spectrometry were assessed. Across the spectrum of glucocorticoid and androgen analytes tested, limits of detection and quantitation were â¼20 fold lower with triple than single quadrupole systems, but the more noticeable improvement was that signal to noise was substantially improved and the linear range wider. These benefits allowed more reliable and concomitant measurement of steroids with substantially different abundances and in smaller volumes of urine.
Journal: Analytical Biochemistry - Volume 538, 1 December 2017, Pages 34-37