Denosumab, a fully human RANKL antibody, reduced bone turnover markers and increased trabecular and cortical bone mass, density, and strength in ovariectomized cynomolgus monkeys Fulltext Access 12 Pages 2011
Lrrn1 is required for formation of the midbrain-hindbrain boundary and organiser through regulation of affinity differences between midbrain and hindbrain cells in chick Fulltext Access 12 Pages 2011
Cooperative functions of Hes/Hey genes in auditory hair cell and supporting cell development Fulltext Access 12 Pages 2011
Dorsal-Ventral patterning: Crescent is a dorsally secreted Frizzled-related protein that competitively inhibits Tolloid proteases Fulltext Access 12 Pages 2011
Blastema induction in aneurogenic state and Prrx-1 regulation by MMPs and FGFs in Ambystoma mexicanum limb regeneration Fulltext Access 12 Pages 2011
Lineage specific trimethylation of H3 on lysine 4 during C. elegans early embryogenesis Fulltext Access 12 Pages 2011
Pinpointing the expression of piRNAs and function of the PIWI protein subfamily during spermatogenesis in the mouse Fulltext Access 12 Pages 2011
Collagen VI is a basement membrane component that regulates epithelial cell-fibronectin interactions Fulltext Access 12 Pages 2011
Distinct tissue distributions and subcellular localizations of differently phosphorylated forms of the myosin regulatory light chain in Drosophila Fulltext Access 12 Pages 2011
Upregulation of paxillin and focal adhesion signaling follows Dystroglycan Complex deletions and promotes a hypertensive state of differentiation Fulltext Access 12 Pages 2011
p130Cas promotes invasiveness of three-dimensional ErbB2-transformed mammary acinar structures by enhanced activation of mTOR/p70S6K and Rac1 Fulltext Access 12 Pages 2011
Identification of a dopaminergic enhancer indicates complexity in vertebrate dopamine neuron phenotype specification Fulltext Access 12 Pages 2011
Molecular subtypes of osteosarcoma identified by reducing tumor heterogeneity through an interspecies comparative approach Fulltext Access 12 Pages 2011
Endothelial cell hyperproliferation and stratification in uteroplacental blood vessels of the black mastiff bat, Molossus rufus Fulltext Access 12 Pages 2011
Cryogenic and low temperature preservation of human placental villous explants – A new way to explore drugs in pregnancy disorders Fulltext Access 12 Pages 2011
Glutamine analogs promote cytoophidium assembly in human and Drosophila cells Fulltext Access 12 Pages 2011
Suppression of edr2-mediated powdery mildew resistance, cell death and ethylene-induced senescence by mutations in ALD1 in Arabidopsis Fulltext Access 12 Pages 2011
Why do patients with psychosis use cannabis and are they ready to change their use? Fulltext Access 12 Pages 2011
Three phases of DiGeorge/22q11 deletion syndrome pathogenesis during brain development: Patterning, proliferation, and mitochondrial functions of 22q11 genes Fulltext Access 12 Pages 2011
Molecular evidence that cortical synaptic growth predominates during the first decade of life in humans Fulltext Access 12 Pages 2011
Comparative statistical mechanics of myosin molecular motors in rat heart, diaphragm and tracheal smooth muscle Fulltext Access 12 Pages 2011
A genetic screen for mutations affecting gonad formation in Drosophila reveals a role for the slit/robo pathway Fulltext Access 12 Pages 2011
Hemogenic endothelium: Origins, regulation, and implications for vascular biology Fulltext Access 12 Pages 2011
Early regulative ability of the neuroepithelium to form cardiac neural crest Fulltext Access 12 Pages 2011
SSDP cofactors regulate neural patterning and differentiation of specific axonal projections Fulltext Access 12 Pages 2011
Telencephalic neural precursor cells show transient competence to interpret the dopaminergic niche of the embryonic midbrain Fulltext Access 12 Pages 2011
Adipocyte derived paracrine mediators of mammary ductal morphogenesis controlled by retinoic acid receptors Fulltext Access 12 Pages 2011
Grainyhead-like 2 regulates neural tube closure and adhesion molecule expression during neural fold fusion Fulltext Access 12 Pages 2011
Extra-embryonic-specific imprinted expression is restricted to defined lineages in the post-implantation embryo Fulltext Access 12 Pages 2011
Conditional expression of the TVA receptor allows clonal analysis of descendents from Cre-expressing progenitor cells Fulltext Access 12 Pages 2011
A Dictyostelium SH2 adaptor protein required for correct DIF-1 signaling and pattern formation Fulltext Access 12 Pages 2011
Structure and optical properties of plant cell wall bio-inspired materials: Cellulose–lignin multilayer nanocomposites Fulltext Access 12 Pages 2011
Shh signalling restricts the expression of Gcm2 and controls the position of the developing parathyroids Fulltext Access 12 Pages 2011
Development of the Drosophila entero-endocrine lineage and its specification by the Notch signaling pathway Fulltext Access 12 Pages 2011
A cell-based model of Nematostella vectensis gastrulation including bottle cell formation, invagination and zippering Fulltext Access 12 Pages 2011
Synovial joint formation requires local Ext1 expression and heparan sulfate production in developing mouse embryo limbs and spine Fulltext Access 12 Pages 2011
Protogenin mediates cell adhesion for ingression and re-epithelialization of paraxial mesodermal cells Fulltext Access 12 Pages 2011
Experimental Sey mouse chimeras reveal the developmental deficiencies of Pax6-null granule cells in the postnatal cerebellum Fulltext Access 12 Pages 2011
C. elegans patched-3 is an essential gene implicated in osmoregulation and requiring an intact permease transporter domain Fulltext Access 12 Pages 2011
An AT-hook gene is required for palea formation and floral organ number control in rice Fulltext Access 12 Pages 2011
Cranial nerve fasciculation and Schwann cell migration are impaired after loss of Npn-1 Fulltext Access 12 Pages 2011
Periaxin is required for hexagonal geometry and membrane organization of mature lens fibers Fulltext Access 12 Pages 2011
Evolution and development of polarized germ cell cysts: New insights from a polychaete worm, Ophryotrocha labronica Fulltext Access 12 Pages 2011
Inositol Trisphosphate-Induced Ca2+ Signaling Modulates Auxin Transport and PIN Polarity Fulltext Access 12 Pages 2011
PDGFRβ Signaling Regulates Mural Cell Plasticity and Inhibits Fat Development Fulltext Access 12 Pages 2011
Spindle Checkpoint Silencing Requires Association of PP1 to Both Spc7 and Kinesin-8 Motors Fulltext Access 12 Pages 2011
Developmental downregulation of Xenopus cyclin E is phosphorylation and nuclear import dependent and is mediated by ubiquitination Fulltext Access 12 Pages 2011
Disrupted dorsal neural tube BMP signaling in the cilia mutant Arl13bhnn stems from abnormal Shh signaling Fulltext Access 12 Pages 2011
The E3 ubiquitin ligase Cullin 4A regulates meiotic progression in mouse spermatogenesis Fulltext Access 12 Pages 2011
Initial diameter of the polar body contractile ring is minimized by the centralspindlin complex Fulltext Access 12 Pages 2011
The gap junctional protein INX-14 functions in oocyte precursors to promote C. elegans sperm guidance Fulltext Access 12 Pages 2011
Drosophila twin spot clones reveal cell division dynamics in regenerating imaginal discs Fulltext Access 12 Pages 2011
Wnt2 signaling is necessary and sufficient to activate the airway smooth muscle program in the lung by regulating myocardin/Mrtf-B and Fgf10 expression Fulltext Access 12 Pages 2011
Developmental Genetics and New Sequencing Technologies: The Rise of Nonmodel Organisms Fulltext Access 12 Pages 2011
Syndecan contributes to heart cell specification and lumen formation during Drosophila cardiogenesis Fulltext Access 12 Pages 2011
Altered differentiation and paracrine stimulation of mammary epithelial cell proliferation by conditionally activated Smoothened Fulltext Access 12 Pages 2011
The Bin3 RNA methyltransferase is required for repression of caudal translation in the Drosophila embryo Fulltext Access 12 Pages 2011
C. elegans ADAMTS ADT-2 regulates body size by modulating TGFβ signaling and cuticle collagen organization Fulltext Access 12 Pages 2011
Wnt4 induces nephronic tubules in metanephric mesenchyme by a non-canonical mechanism Fulltext Access 12 Pages 2011
Drosophila adducin regulates Dlg phosphorylation and targeting of Dlg to the synapse and epithelial membrane Fulltext Access 12 Pages 2011
The transcription factor HLH-2/E/Daughterless regulates anchor cell invasion across basement membrane in C. elegans Fulltext Access 12 Pages 2011
The Hem protein mediates neuronal migration by inhibiting WAVE degradation and functions opposite of Abelson tyrosine kinase Fulltext Access 12 Pages 2011
Second order regulator Collier directly controls intercalary-specific segment polarity gene expression Fulltext Access 12 Pages 2011
A dissection of the teashirt and tiptop genes reveals a novel mechanism for regulating transcription factor activity Fulltext Access 12 Pages 2011
Expression of Drosophila Cabut during early embryogenesis, dorsal closure and nervous system development Fulltext Access 12 Pages 2011
Mechanism of the positive effect of poly(ethylene glycol) addition in enzymatic hydrolysis of steam pretreated lignocelluloses Fulltext Access 12 Pages 2011
DNA double-strand break repair pathways, chromosomal rearrangements and cancer Fulltext Access 12 Pages 2011
Transglutaminase 2 regulates early chondrogenesis and glycosaminoglycan synthesis Fulltext Access 12 Pages 2011
Cardiac remodeling in Drosophila arises from changes in actin gene expression and from a contribution of lymph gland-like cells to the heart musculature Fulltext Access 12 Pages 2011
Hedgehog signalling is required for perichondral osteoblast differentiation in zebrafish Fulltext Access 12 Pages 2011
The floor plate is sufficient for development of the sclerotome and spine without the notochord Fulltext Access 12 Pages 2011
Zebrafish wnt9a is expressed in pharyngeal ectoderm and is required for palate and lower jaw development Fulltext Access 12 Pages 2011
Drosophila spoonbill encodes a dual-specificity A-kinase anchor protein essential for oogenesis Fulltext Access 12 Pages 2011
A BAC transgenic Hes1-EGFP reporter reveals novel expression domains in mouse embryos Fulltext Access 12 Pages 2011
Tissue specific characterisation of Lim-kinase 1 expression during mouse embryogenesis Fulltext Access 12 Pages 2011
A screen for hoxb1-regulated genes identifies ppp1r14al as a regulator of the rhombomere 4 Fgf-signaling center Fulltext Access 12 Pages 2011
The native structure of cytoplasmic dynein at work translocating vesicles in Paramecium Fulltext Access 12 Pages 2011
Migration of epithelial cells on laminins: RhoA antagonizes directionally persistent migration Fulltext Access 12 Pages 2011
Homeodomain-only protein HOP is a novel modulator of late differentiation in keratinocytes Fulltext Access 12 Pages 2011
Ret finger protein 2 enhances ionizing radiation-induced apoptosis via degradation of AKT and MDM2 Fulltext Access 12 Pages 2011
Expression of keratinocyte biomarkers is governed by environmental biomechanics Fulltext Access 12 Pages 2011
piRNA-Associated Germline Nuage Formation and Spermatogenesis Require MitoPLD Profusogenic Mitochondrial-Surface Lipid Signaling Fulltext Access 12 Pages 2011
MITOPLD Is a Mitochondrial Protein Essential for Nuage Formation and piRNA Biogenesis in the Mouse Germline Fulltext Access 12 Pages 2011
Rspo3 Binds Syndecan 4 and Induces Wnt/PCP Signaling via Clathrin-Mediated Endocytosis to Promote Morphogenesis Fulltext Access 12 Pages 2011
Endothelial Smad4 Maintains Cerebrovascular Integrity by Activating N-Cadherin through Cooperation with Notch Fulltext Access 12 Pages 2011