On the paradox of ion channel blockade and its benefits in the treatment of Alzheimer disease Fulltext Access 7 Pages 2005
From psychophysiological insomnia to organic sleep disturbances: A continuum in late onset insomnia - with special concerns relating to its treatment Fulltext Access 7 Pages 2005
Does dysregulation of key epigenetic and biochemical pathways occur in postulated vasoactive neuropeptide autoimmune disorders? Fulltext Access 7 Pages 2005
The delta opioid receptor 1 is expressed by proliferating bile ductules in rats with cholestasis: Implications for the study of liver regeneration and malignant transformation of biliary epithelium Fulltext Access 7 Pages 2005
The molecular relationship between deficient UDP-galactose uridyl transferase (GALT) and ceramide galactosyltransferase (CGT) enzyme function: A possible cause for poor long-term prognosis in classic galactosemia Fulltext Access 7 Pages 2005
Role of oxidative metabolites of cocaine in toxicity and addiction: oxidative stress and electron transfer Fulltext Access 7 Pages 2005
Possible interplay between vitamin C deficiency and prolactin in pregnant women with premature rupture of membranes: facts and hypothesis Fulltext Access 7 Pages 2005
Music, memory, and Alzheimer's disease: is music recognition spared in dementia, and how can it be assessed? Fulltext Access 7 Pages 2005
The incorporation of iodine in thyroid hormone may stem from its role as a prehistoric signal of ecologic opportunity: An evolutionary perspective and implications for modern diseases Fulltext Access 7 Pages 2005
Therapeutic and preventive interventions for postulated vasoactive neuropeptide autoimmune fatigue-related disorders Fulltext Access 7 Pages 2005
An alternative hypothesis to the obesity epidemic: Obesity is due to increased maternal body size, birth size, growth rate, and height Fulltext Access 7 Pages 2005
Pharmacologic manipulation of the ataxia-telangiectasia mutated gene product as an intervention in age-related disease Fulltext Access 7 Pages 2005
Integrating the theories of Darwin and Bernoulli: Maladaptive baroreceptor network dysfunction may explain the pathogenesis of aortic aneurysms Fulltext Access 7 Pages 2005
Immunodominant viral peptides as determinants of cross-reactivity in the immune system - Can we develop wide spectrum viral vaccines? Fulltext Access 7 Pages 2005
Large-scale randomised trials - a misguided approach to clinical research Fulltext Access 7 Pages 2005
The use of transformed Escherichia coli for experimental angiogenesis induced by regulated in situ production of vascular endothelial growth factor - an alternative gene therapy Fulltext Access 7 Pages 2005
Kaiser Wilhelm syndrome: Obstetric trauma or placental insult in a historical case mimicking Erb's palsy Fulltext Access 7 Pages 2005
5-Hydroxytryptophan plus SSRIs for interferon-induced depression: Synergistic mechanisms for normalizing synaptic serotonin Fulltext Access 7 Pages 2005
Dominant and opportunistic leukemic clones: Proposal for a pathogenesis-oriented classification in acute myeloid leukemia Fulltext Access 7 Pages 2005
Unifying mechanism for addiction and toxicity of abused drugs with application to dopamine and glutamate mediators: Electron transfer and reactive oxygen species Fulltext Access 7 Pages 2005
The role of vestibular system and the cerebellum in adapting to gravitoinertial, spatial orientation and postural challenges of REM sleep Fulltext Access 7 Pages 2005
Personality profiles of normal healthy research volunteers: a potential concern for clinical drug trial investigators? Fulltext Access 7 Pages 2005
Adipocyte insensitivity syndromes - novel approach to nutritional metabolic problems including obesity and obesity related disorders Fulltext Access 7 Pages 2005
All the adult stem cells, where do they all come from? An external source for organ-specific stem cell pools Fulltext Access 7 Pages 2005
Thinking the unthinkable: Alzheimer's, Creutzfeldt-Jakob and Mad Cow disease: the age-related reemergence of virulent, foodborne, bovine tuberculosis or losing your mind for the sake of a shake or burger Fulltext Access 7 Pages 2005
Simplified quantification of nicotinic receptors with 2[18F]F-A-85380 PET Fulltext Access 7 Pages 2005
Relative uptake of technetium 99m stannous colloid by neutrophils and monocytes is altered by gram-negative infection Fulltext Access 7 Pages 2005
Evaluation of (R)-[11C]verapamil as PET tracer of P-glycoprotein function in the blood-brain barrier: kinetics and metabolism in the rat Fulltext Access 7 Pages 2005
Characterization of 123I-iodo-α-methyltyrosine transport in rat lymphoma cells Fulltext Access 7 Pages 2005
The experimental study on the radioimmunotherapy of the nasopharyngeal carcinoma overexpressing HER2/neu in nude mice model with intratumoral injection of 188Re-herceptin Fulltext Access 7 Pages 2005
Synthesis and evaluation of 2-[18F]fluoro-CP-118,954 for the in vivo mapping of acetylcholinesterase Fulltext Access 7 Pages 2005
Deferoxamine as a chelator for 67Ga in the preparation of antibody conjugates Fulltext Access 7 Pages 2005
Synthesis and in vivo evaluation of [11C]PJ34, a potential radiotracer for imaging the role of PARP-1 in necrosis Fulltext Access 7 Pages 2005
In vivo evaluation of [123I]-3-(4-iodobenzyl)-1,2,3,4-tetrahydro-8-hydroxychromeno[3,4-c]pyridin-5-one: a presumed dopamine D4 receptor ligand for SPECT studies Fulltext Access 7 Pages 2005
In vivo apoptosis detection with radioiodinated Annexin V in LoVo tumour-bearing mice following Tipifarnib (Zarnestra, R115777) farnesyltransferase inhibitor therapy Fulltext Access 7 Pages 2005
Synthesis and in vitro and in vivo evaluation of three radioiodinated nitroimidazole analogues as tumor hypoxia markers Fulltext Access 7 Pages 2005
[131I]Iodoazomycin arabinoside for low-dose-rate isotope radiotherapy: radiolabeling, stability, long-term whole-body clearance and radiation dosimetry estimates in mice Fulltext Access 7 Pages 2005
The smoking gun: many conditions associated with tobacco exposure may be attributable to paradoxical compensatory autonomic responses to nicotine Fulltext Access 7 Pages 2005
Positron emission tomography studies in eating disorders: multireceptor brain imaging, correlates with behavior and implications for pharmacotherapy Fulltext Access 7 Pages 2005
Pretargeted radioimmunotherapy in tumored mice using an in vivo 212Pb/212Bi generator Fulltext Access 7 Pages 2005
Resolution, sensitivity and precision with autoradiography and small animal positron emission tomography: implications for functional brain imaging in animal research Fulltext Access 7 Pages 2005
Cy5.5-DTPA-galactosyl-dextran: a fluorescent probe for in vivo measurement of receptor biochemistry Fulltext Access 7 Pages 2005
Synthesis and biological evaluation of (E)-3-styrylpyridine derivatives as amyloid imaging agents for Alzheimer's disease Fulltext Access 7 Pages 2005
Fully automated synthesis of [18F]fluoromisonidazole using a conventional [18F]FDG module Fulltext Access 7 Pages 2005
Preparation of high specific activity 86Y using a small biomedical cyclotron Fulltext Access 7 Pages 2005
Tubal occlusion causing infertility due to an excessive inflammatory response in patients with predisposition for keloid formation Fulltext Access 7 Pages 2005
Identification of Human UDP-Glucuronosyltransferase Isoform(s) Responsible for the Glucuronidation of 2-(4-Chlorophenyl)-5-(2-Furyl)-4-Oxazoleacetic Acid (TA-1801A) Fulltext Access 7 Pages 2005
Preformulation studies and estimation of brain penetration for two alpidem analogues having anticonvulsant activity Fulltext Access 7 Pages 2005
Protective effect of SLNs encapsulation on the photodegradation and thermal degradation of retinyl palmitate introduced in hydroxyethylcellulose gel Fulltext Access 7 Pages 2005
Effect of UV light exposure on hydrophilic polymers used as drug release modulators in solid dosage forms Fulltext Access 7 Pages 2005
Controlled release of oligonucleotide/polyethyleneimine complexes from PLGA-based microspheres: potential of spray-drying technique Fulltext Access 7 Pages 2005
Effect of three types of additives in poor solvent on preparation of sustained-release nitrendipine microspheres by the quasi-emulsion solvent diffusion method Fulltext Access 7 Pages 2005
Encapsulation of ganciclovir in albumin nanoparticles enhances the thymidine kinase suicide gene therapy Fulltext Access 7 Pages 2005
Transport study of macromolecules through microporous poly(2-hydroxyethyl methacrylate) sponges Fulltext Access 7 Pages 2005
Rheological characteristics and diffusion processes in mixed cellulose hydrogel matrices Fulltext Access 7 Pages 2005
Synthesis and in vitro characterization of a novel poly(acrylic acid)-glutathione conjugate Fulltext Access 7 Pages 2005
Pharmacokinetic Analysis of the Tissue Distribution of Octaarginine Modified Liposomes in Mice Fulltext Access 7 Pages 2005
The Effects of Culture Conditions on CYP3A4 and MDR1 mRNA Induction by 1α,25-Dihydroxyvitamin D3 in Human Intestinal Cell Lines, Caco-2 and LS180â Fulltext Access 7 Pages 2005
Simultaneous Determination of Single Nucleotide Polymorphisms of MDR1 Genes by Electrochemical DNA Chip Fulltext Access 7 Pages 2005
Prediction of Absorbability of Poorly Water-soluble Drugs Based on Permeability Obtained through Modified In Vitro Chamber Method Fulltext Access 7 Pages 2005
Characterization of Secretory Intestinal Transport of Phenolsulfonphthalein Fulltext Access 7 Pages 2005
Effectiveness of Pirotiodecane, Absorption Enhancer, on Nasal Absorption in Rabbits Fulltext Access 7 Pages 2005
In Vitro Inhibitory Effect of 1-Aminobenzotriazole on Drug Oxidations in Human Liver Microsomes: a Comparison with SKF-525A Fulltext Access 7 Pages 2005
Long-term Levothyroxine Treatment Decreases the Oral Bioavailability of Cyclosporin A by Inducing P-glycoprotein in Small Intestine Fulltext Access 7 Pages 2005
Une nouvelle thérapie ciblée avec le bortézomib, médicament oncologique de l'année 2004 Fulltext Access 7 Pages 2005
Implication de la voie PI3K/Akt dans le cancer de la prostate. Nouvelles stratégies pour concevoir des thérapies ciblées Fulltext Access 7 Pages 2005
La vinflunine, nouvel agent anticancéreux fluoré dérivé des alcaloïdes de Vinca Fulltext Access 7 Pages 2005
Determination of polymorph conversion of an active pharmaceutical ingredient in wet granulation using NIR calibration models generated from the premix blends Fulltext Access 7 Pages 2005
Effect of Fruit Juices on the Oral Bioavailability of Fexofenadine in Rats Fulltext Access 7 Pages 2005
Latent chlamydial infections: The probable cause of a wide spectrum of human diseases Fulltext Access 7 Pages 2005
Lifetime high calcium intake increases osteoporotic fracture risk in old age Fulltext Access 7 Pages 2005
Diabetes mellitus, tuberculosis and the mycobacteria: Two millenia of enigma Fulltext Access 7 Pages 2005
The future of 'pure' medical science: The need for a new specialist professional research system Fulltext Access 7 Pages 2005
Microemulsions as Colloidal Vehicle Systems for Dermal Drug Delivery. Part V: Microemulsions without and with Glycolipid as Penetration Enhancer Fulltext Access 7 Pages 2005
Novel Method for Studying Photolability of Topical Formulations: A Case Study of Titanium Dioxide Stabilization of Ketoprofen Fulltext Access 7 Pages 2005
Oxycodone Pharmacokinetics and Pharmacodynamics in the Rat in the Presence of the P-Glycoprotein Inhibitor PSC833 Fulltext Access 7 Pages 2005
Biowaiver monographs for immediate release solid oral dosage forms based on biopharmaceutics classification system (BCS) literature data: Chloroquine phosphate, chloroquine sulfate, and chloroquine hydrochloride* Fulltext Access 7 Pages 2005
Application of NIR Spectroscopy in Polymorphic Analysis: Study of Pseudo-Polymorphs Stability Fulltext Access 7 Pages 2005
Solubilization and Preformulation Studies on PG-300995 (An Anti-HIV Drug) Fulltext Access 7 Pages 2005
Nondestructive Analysis of Tablet Coating Thicknesses Using Terahertz Pulsed Imaging Fulltext Access 7 Pages 2005
Matrixâassisted laser desorption/ionization timeâofâflight mass spectrometry for quantitation and molecular stability assessment of insulin entrapped within PLGA nanoparticles Fulltext Access 7 Pages 2005
Interâ and intralaboratory variation of in vitro diffusion cell measurements: An international multicenter study using quasiâstandardized methods and materials Fulltext Access 7 Pages 2005
Kinetics of glycine crystallization during freezing of sucrose/glycine excipient systems Fulltext Access 7 Pages 2005
Carbon nanotube-mediated delivery of peptides and genes to cells: translating nanobiotechnology to therapeutics Fulltext Access 7 Pages 2005
Oil/water “hand-bag like structures”: how interfacial rheology can help to understand their formation? Fulltext Access 7 Pages 2005
Dissolution of pH responsive formulations in media resembling intestinal fluids: bicarbonate versus phosphate buffers Fulltext Access 7 Pages 2005
The effect of water on matrix formation in sustained release tablets containing poly(ethyl acrylate, methyl methacrylate) Fulltext Access 7 Pages 2005
Rutin and quercetin gastro-resistant microparticles obtained by spray-drying technique Fulltext Access 7 Pages 2005