Synthesis of a new series of heterocyclic scaffolds for medicinal purposes Fulltext Access 8 Pages 2006
Indomethacin-loaded polymeric nanocarriers based on amphiphilic polyphosphazenes with poly (N-isopropylacrylamide) and ethyl tryptophan as side groups: Preparation, in vitro and in vivo evaluation Fulltext Access 8 Pages 2006
Uptake and metabolism of novel biodegradable poly (glycerol-adipate) nanoparticles in DAOY monolayer Fulltext Access 8 Pages 2006
In vitro and in vivo gene-transferring characteristics of novel cationic lipids, DMKD (O,O'-dimyristyl-N-lysyl aspartate) and DMKE (O,O'-dimyristyl-N-lysyl glutamate) Fulltext Access 8 Pages 2006
Inhibition of peritoneal dissemination of tumor cells by single dosing of phosphodiester CpG oligonucleotide/cationic liposome complex Fulltext Access 8 Pages 2006
PEGylated gene nanocarriers based on block catiomers bearing ethylenediamine repeating units directed to remarkable enhancement of photochemical transfection Fulltext Access 8 Pages 2006
Protein diffusion in agarose hydrogel in situ measured by improved refractive index method Fulltext Access 8 Pages 2006
Effects of alginate inclusion on the vector properties of chitosan-based nanoparticles Fulltext Access 8 Pages 2006
Accelerated blood clearance of PEGylated liposomes upon repeated injections: Effect of doxorubicin-encapsulation and high-dose first injection Fulltext Access 8 Pages 2006
Spleen plays an important role in the induction of accelerated blood clearance of PEGylated liposomes Fulltext Access 8 Pages 2006
Synthesis and biological evaluation of 1β-methylcarbapenems having cyclic thiourea moieties and their related compounds Fulltext Access 8 Pages 2006
Release of anti-restenosis drugs from poly(ethylene oxide)-poly(dl-lactic-co-glycolic acid) nanoparticles Fulltext Access 8 Pages 2006
Affinity of 1-aryl-1,2,3,4-tetrahydroisoquinoline derivatives to the ion channel binding site of the NMDA receptor complex Fulltext Access 8 Pages 2006
Synthesis of new esters and oximes with 4-aminobicyclo[2.2.2]octane structure and evaluation of their antitrypanosomal and antiplasmodial activities Fulltext Access 8 Pages 2006
Synthesis, in vitro antiproliferative activities, and Chk1 inhibitory properties of indolylpyrazolones and indolylpyridazinedione Fulltext Access 8 Pages 2006
Cyclic and branched acyl chain galactoglycerolipids and their effect on anti-tumor-promoting activity Fulltext Access 8 Pages 2006
Action mechanisms and structure-activity relationships of PI3Kγ inhibitors on the enzyme: a molecular modeling study Fulltext Access 8 Pages 2006
Synthesis of pharmaceutically important condensed heterocyclic 4,6-disubstituted-1,2,4-triazolo-1,3,4-thiadiazole derivatives as antimicrobials Fulltext Access 8 Pages 2006
Synthesis and antiproliferative activity of some 5-substituted 2-(2,4-dihydroxyphenyl)-1,3,4-thiadiazoles Fulltext Access 8 Pages 2006
Synthesis and cytotoxic activity of substituted 2-phenyl-3-hydroxy-4(1H)-quinolinones-7-carboxylic acids and their phenacyl esters Fulltext Access 8 Pages 2006
Syntheses and antimicrobial activities of a series of new bis-quaternary ammonium compounds Fulltext Access 8 Pages 2006
Synthesis and QSAR studies of novel triazole compounds containing thioamide as potential antifungal agents Fulltext Access 8 Pages 2006
(±)-3′-O, 4′-O-dicynnamoyl-cis-khellactone, a derivative of (±)-praeruptorin A, reverses P-glycoprotein mediated multidrug resistance in cancer cells Fulltext Access 8 Pages 2006
Myocardial regeneration strategies using human embryonic stem cell-derived cardiomyocytes Fulltext Access 8 Pages 2006
Stabilisation of deoxyribonuclease in hydrofluoroalkanes using miscible vinyl polymers Fulltext Access 8 Pages 2006
Controlled release of plasmid DNA from hydrogels prepared from gelatin cationized by different amine compounds Fulltext Access 8 Pages 2006
Biodegradable polymeric microspheres with “open/closed” pores for sustained release of human growth hormone Fulltext Access 8 Pages 2006
Nano-fibrous scaffold for controlled delivery of recombinant human PDGF-BB Fulltext Access 8 Pages 2006
Study on drug release behaviour of CDHA/chitosan nanocomposites-Effect of CDHA nanoparticles Fulltext Access 8 Pages 2006
Novel drug release profiles from micellar solutions of PLA–PEO–PLA triblock copolymers Fulltext Access 8 Pages 2006
Inhibition of gentamicin binding to rat renal brush-border membrane by megalin ligands and basic peptides Fulltext Access 8 Pages 2006
Pharmaceutical and immunological evaluation of a single-dose hepatitis B vaccine using PLGA microspheres Fulltext Access 8 Pages 2006
The short consensus repeats 1 and 2, not the cytoplasmic domain, of human CD46 are crucial for infection of subgroup B adenovirus serotype 35 Fulltext Access 8 Pages 2006
Gastroretentive Accordion Pill: Enhancement of riboflavin bioavailability in humans Fulltext Access 8 Pages 2006
Effects of Na+/H+ exchanger inhibitors on subcellular localisation of endocytic organelles and intracellular dynamics of protein transduction domains HIV–TAT peptide and octaarginine Fulltext Access 8 Pages 2006
Identification and evaluation of antioxidant, analgesic/anti-inflammatory activity of the most active ninhydrin–phenol adducts synthesized Fulltext Access 8 Pages 2006
Linear poly(amido amine)s with secondary and tertiary amino groups and variable amounts of disulfide linkages: Synthesis and in vitro gene transfer properties Fulltext Access 8 Pages 2006
DNA polyplexes based on degradable oligoethylenimine-derivatives: Combination with EGF receptor targeting and endosomal release functions Fulltext Access 8 Pages 2006
Systematic lactose-functionalization of amphiphilic octaamine macrocycle as a gene carrier. Optimization of the charge, size, toxicity, and receptor factors for hepatocyte targeting Fulltext Access 8 Pages 2006
Efficient gene transfer by pullulan–spermine occurs through both clathrin- and raft/caveolae-dependent mechanisms Fulltext Access 8 Pages 2006
Ion pair-mediated transport of metoprolol across a three lipid-component PAMPA system Fulltext Access 8 Pages 2006
Preparation, characterization and anticoagulation of curcumin-eluting controlled biodegradable coating stents Fulltext Access 8 Pages 2006
In-vivo efficacy of novel paclitaxel nanoparticles in paclitaxel-resistant human colorectal tumors Fulltext Access 8 Pages 2006
Non-viral adiponectin gene therapy into obese type 2 diabetic mice ameliorates insulin resistance Fulltext Access 8 Pages 2006
Enhanced transfection of primary cortical cultures using arginine-grafted PAMAM dendrimer, PAMAM-Arg Fulltext Access 8 Pages 2006
Anti-angiogenic inhibition of tumor growth by systemic delivery of PEI-g-PEG-RGD/pCMV-sFlt-1 complexes in tumor-bearing mice Fulltext Access 8 Pages 2006
Specific and sensitive analysis of nefopam and its main metabolite desmethyl-nefopam in human plasma by liquid chromatography-ion trap tandem mass spectrometry Fulltext Access 8 Pages 2006
Enantiomeric resolution of doxazosin mesylate and its process-related substances on polysaccharide chiral stationary phases Fulltext Access 8 Pages 2006
Simultaneous determination of triamcinolone acetonide and oxymetazoline hydrochloride in nasal spray formulations by HPLC Fulltext Access 8 Pages 2006
Quantitative determination of diclofenac sodium and aminophylline in injection solutions by FT-Raman spectroscopy Fulltext Access 8 Pages 2006
High sensitive analysis of rat serum bile acids by liquid chromatography/electrospray ionization tandem mass spectrometry Fulltext Access 8 Pages 2006
Structure elucidation and conformational study of V8: A novel synthetic non peptide AT1 antagonist Fulltext Access 8 Pages 2006
Determination of surface-bound hydroxypropylcellulose (HPC) on drug particles in colloidal dispersions using size exclusion chromatography: A comparison of ELS and RI detection Fulltext Access 8 Pages 2006
Validation and implementation of a liquid chromatography/tandem mass spectrometry assay to quantitate ABT-751, ABT-751 glucuronide, and ABT-751 sulfate in human plasma for clinical pharmacology studies Fulltext Access 8 Pages 2006
Diastereoisomeric resolution of a pronucleotide using solid phase extraction and high performance liquid chromatography: Application to a stereoselective decomposition kinetic in cell extracts Fulltext Access 8 Pages 2006
Differential pulse voltammetric determination of nimesulide in pharmaceutical formulation and human serum at glassy carbon electrode modified by cysteic acid/CNTs based on electrochemical oxidation of l-cysteine Fulltext Access 8 Pages 2006
Stability evaluation of amoxicillin in a solid premix veterinary formulation by monitoring the degradation products through a new HPLC analytical method Fulltext Access 8 Pages 2006
Cobalt tetrasulphonated phthalocyanine immobilized on poly-l-lysine film onto glassy carbon electrode as amperometric sensor for cysteine Fulltext Access 8 Pages 2006
Analysis of flavonoids from propolis by on-line HPLC–electrospray mass spectrometry Fulltext Access 8 Pages 2006
Comparison of FT-NIR transmission and UV–vis spectrophotometry to follow the mixing kinetics and to assay low-dose tablets containing riboflavin Fulltext Access 8 Pages 2006
Supercritical fluid chromatography–tandem mass spectrometry for fast bioanalysis of R/S-warfarin in human plasma Fulltext Access 8 Pages 2006
Identification and analysis of absorbed and metabolic components in rat plasma after oral administration of ‘Shuangdan’ granule by HPLC–DAD–ESI-MS/MS Fulltext Access 8 Pages 2006
Potentiometric behaviour of ion selective electrodes based on iron porphyrins: The influence of porphyrin substituents on the response properties and analytical determination of diclofenac in pharmaceutical formulations Fulltext Access 8 Pages 2006
Quantitative assay of lorazepam and its metabolite glucuronide by reverse-phase liquid chromatography-tandem mass spectrometry in human plasma and urine samples Fulltext Access 8 Pages 2006
Effective on-line purification for cationic compounds in rat bile using a column-switching LC technique Fulltext Access 8 Pages 2006
The application of inductively coupled plasma mass spectrometry in pharmaceutical and biomedical analysis Fulltext Access 8 Pages 2006
Sensitive determination of G-protein-coupled receptor binding ligands by solid phase extraction–electrospray ionization–mass spectrometry Fulltext Access 8 Pages 2006
Validated LC/MS/MS assay for curcumin and tetrahydrocurcumin in rat plasma and application to pharmacokinetic study of phospholipid complex of curcumin Fulltext Access 8 Pages 2006
High-performance liquid chromatography-atmospheric pressure chemical ionisation-mass spectrometry determination of zaleplon in human plasma Fulltext Access 8 Pages 2006
Identification and determination of nucleosides in Cordyceps sinensis and its substitutes by high performance liquid chromatography with mass spectrometric detection Fulltext Access 8 Pages 2006
Design, synthesis, and evaluation of new type of l-amino acids containing pyridine moiety as nitric oxide synthase inhibitor Fulltext Access 8 Pages 2006
Structure–activity relationship study of flavone compounds with anti-HIV-1 integrase activity: A density functional theory study Fulltext Access 8 Pages 2006
Synthesis and trypanocidal activity of 1,4-bis-(3,4,5-trimethoxy-phenyl)-1,4-butanediol and 1,4-bis-(3,4-dimethoxyphenyl)-1,4-butanediol Fulltext Access 8 Pages 2006
Highly antiproliferative, low-calcemic, side-chain amide and hydroxamate analogs of the hormone 1α,25-dihydroxyvitamin D3 Fulltext Access 8 Pages 2006
Synthesis, characterization, antibacterial and cytotoxic study of platinum (IV) complexes Fulltext Access 8 Pages 2006
Novel bioactive bromopyrrole alkaloids from the Mediterranean sponge Axinella verrucosa Fulltext Access 8 Pages 2006
Synthesis and biological activity of N,N-dialkylaminoalkyl-substituted bisindolyl and diphenyl pyrazolone derivatives Fulltext Access 8 Pages 2006
Synthesis and receptor binding affinity of carboxylate analogues of the mannose 6-phosphate recognition marker Fulltext Access 8 Pages 2006
Measurement of neurotransmitters from extracellular fluid in brain by in vivo microdialysis and chromatography–mass spectrometry Fulltext Access 8 Pages 2006
Synthesis and biological activity of tricyclic analogues of 9-{[cis-1′,2′-bis(hydroxymethyl)cycloprop-1′-yl]methyl}guanine Fulltext Access 8 Pages 2006
Ether derivatives of 3-piperidinopropan-1-ol as non-imidazole histamine H3 receptor antagonists Fulltext Access 8 Pages 2006
Design, synthesis, and bioactivity of simplified paclitaxel analogs based on the T-Taxol bioactive conformation Fulltext Access 8 Pages 2006
Determination of hexoestrol residues in animal tissues based on enzyme-linked immunosorbent assay and comparison with liquid chromatography–tandem mass spectrometry Fulltext Access 8 Pages 2006
Development and validation of a sensitive liquid chromatography/electrospray tandem mass spectrometry assay for the quantification of olanzapine in human plasma Fulltext Access 8 Pages 2006
Determination of plant and enterolignans in human serum by high-performance liquid chromatography with tandem mass spectrometric detection Fulltext Access 8 Pages 2006
An HPLC chromatographic reactor approach for investigating the hydrolytic stability of a pharmaceutical compound Fulltext Access 8 Pages 2006
Analysis of Indian mint (Mentha spicata) for essential, trace and toxic elements and its antioxidant behaviour Fulltext Access 8 Pages 2006