Improved anti-oxidant activity of superoxide dismutase by direct chemical modification Fulltext Access 8 Pages 2006
Design of poly(ethylene glycol)-tethered copolymers as novel mucoadhesive drug delivery systems Fulltext Access 8 Pages 2006
Study of formulation variables influencing the drug release rate from matrix tablets by experimental design Fulltext Access 8 Pages 2006
Pharmacokinetics of intravenously administered stealth liposomal doxorubicin modulated with verapamil in rats Fulltext Access 8 Pages 2006
Aqueous HPMCAS coatings: Effects of formulation and processing parameters on drug release and mass transport mechanisms Fulltext Access 8 Pages 2006
Integrity and stability studies of precipitated rhBMP-2 microparticles with a focus on ATR-FTIR measurements Fulltext Access 8 Pages 2006
Considerations about the theoretically expected crushing strength of tablets from binary powder mixtures: Double layer tablets versus arithmetic additivity rule Fulltext Access 8 Pages 2006
Incorporation of camptothecin into N-phthaloyl chitosan-g-mPEG self-assembly micellar system Fulltext Access 8 Pages 2006
Preparation and characterization of polymeric micelles for solubilization of poorly soluble anticancer drugs Fulltext Access 8 Pages 2006
Preparation and in vitro evaluation of lipidic carriers and fillers for inhalation Fulltext Access 8 Pages 2006
W/O microemulsions for ocular delivery: Evaluation of ocular irritation and precorneal retention Fulltext Access 8 Pages 2006
Controlled release of avermectin from porous hollow silica nanoparticles: Influence of shell thickness on loading efficiency, UV-shielding property and release Fulltext Access 8 Pages 2006
Loading and mobility of spin-labeled insulin in physiologically responsive complexation hydrogels intended for oral administration Fulltext Access 8 Pages 2006
Synthesis and QSAR studies on 5-[2-(2-methylprop1-enyl)-1H benzimidazol-1yl]-4,6-diphenyl-pyrimidin-2-(5H)-thione derivatives as antibacterial agents Fulltext Access 8 Pages 2006
Novel oral formulation safely improving intestinal absorption of poorly absorbable drugs: Utilization of polyamines and bile acids Fulltext Access 8 Pages 2006
Delivery of the antibiotic gentamicin sulphate from precipitation cast matrices of polycaprolactone Fulltext Access 8 Pages 2006
Incorporation of protein-eluting microspheres into biodegradable nerve guidance channels for controlled release Fulltext Access 8 Pages 2006
Rapid deswelling of semi-IPNs with nanosized tracts in response to pH and temperature Fulltext Access 8 Pages 2006
Nasal immunization studies using liposomes loaded with tetanus toxoid and CpG-ODN Fulltext Access 8 Pages 2006
Rho GDP dissociation inhibitors as potential targets for anticancer treatment Fulltext Access 8 Pages 2006
Subcutaneous delivery of insulin loaded poly(fumaric-co-sebacic anhydride) microspheres to type 1 diabetic rats Fulltext Access 8 Pages 2006
Effect of GDNF-releasing biodegradable microspheres on the function and the survival of intrastriatal fetal ventral mesencephalic cell grafts Fulltext Access 8 Pages 2006
Investigation of nanocapsules stabilization by amorphous excipients during freeze-drying and storage Fulltext Access 8 Pages 2006
A new drug nanocarrier consisting of chitosan and hydoxypropylcyclodextrin Fulltext Access 8 Pages 2006
Distribution characteristics of orally administered olamufloxacin, a newly synthesized fluoroquinolone antibacterial, in lung epithelial lining fluid and alveolar macrophage in rats Fulltext Access 8 Pages 2006
Preparation and in vitro/in vivo evaluation of sustained-release metformin hydrochloride pellets Fulltext Access 8 Pages 2006
Protection of the peptide glutathione by complex formation with α-cyclodextrin: NMR spectroscopic analysis and stability study Fulltext Access 8 Pages 2006
Modulated release metoprolol succinate formulation based on ionic interactions: In vivo proof of concept Fulltext Access 8 Pages 2006
Characterization and in vivo evaluation of ocular minitablets prepared with different bioadhesive Carbopol–starch components Fulltext Access 8 Pages 2006
Influence of nanomechanical crystal properties on the comminution process of particulate solids in spiral jet mills Fulltext Access 8 Pages 2006
Solid lipid nanoparticles can effectively bind DNA, streptavidin and biotinylated ligands Fulltext Access 8 Pages 2006
Development of an in vitro/in vivo correlation for lipid formulations of EMD 50733, a poorly soluble, lipophilic drug substance Fulltext Access 8 Pages 2006
Assessing the re-crystallization behaviour of amorphous lactose using the RH-perfusion cell Fulltext Access 8 Pages 2006
Evaluation of the antioxidant activity of soybean extract by different in vitro methods and investigation of this activity after its incorporation in topical formulations Fulltext Access 8 Pages 2006
Transdermal drug delivery system (TDDS) adhesion as a critical safety, efficacy and quality attribute Fulltext Access 8 Pages 2006
Use of κ-carrageenan as alternative pelletisation aid to microcrystalline cellulose in extrusion/spheronisation. II. Influence of drug and filler type Fulltext Access 8 Pages 2006
Synthesis and leishmanicidal activities of 1-(4-X-phenyl)-N′-[(4-Y-phenyl)methylene]-1H-pyrazole-4-carbohydrazides Fulltext Access 8 Pages 2006
Synthesis and in vitro microbiological evaluation of imidazo(4,5-b)pyridinylethoxypiperidones Fulltext Access 8 Pages 2006
Physico-chemical characterization of disoxaril–dimethyl-β-cyclodextrin inclusion complex and in vitro permeation studies Fulltext Access 8 Pages 2006
Synthesis of oxysterols and nitrogenous sterols with antileishmanial and trypanocidal activities Fulltext Access 8 Pages 2006
Synthesis and biological activity of 6H-isoindolo[2,1-a]indol-6-ones, analogues of batracylin, and related compounds Fulltext Access 8 Pages 2006
Isothiazoles. Part XV. A mild and efficient synthesis of new antiproliferative 5-sulfanylsubstituted 3-alkylaminoisothiazole 1,1-dioxides Fulltext Access 8 Pages 2006
A density functional study of flavonoid compounds with anti-HIV activity Fulltext Access 8 Pages 2006
Induction of promotive rather than suppressive immune responses from a novel NKT cell repertoire Vα19 NKT cell with α-mannosyl ceramide analogues consisting of the immunosuppressant ISP-I as the sphingosine unit Fulltext Access 8 Pages 2006
Syntheses of new substituted triazino tetrahydroisoquinolines and β-carbolines as novel antileishmanial agents1 Fulltext Access 8 Pages 2006
Structural optimization of a “smart” doxorubicin–polypeptide conjugate for thermally targeted delivery to solid tumors Fulltext Access 8 Pages 2006
Synthesis and antiamoebic activity of new 1-N-substituted thiocarbamoyl-3,5-diphenyl-2-pyrazoline derivatives and their Pd(II) complexes Fulltext Access 8 Pages 2006
Synthesis and antiproliferative activities of indolin-2-one derivatives bearing amino acid moieties Fulltext Access 8 Pages 2006
Quantitative structure activity relationship studies of aryl heterocycle-based thrombin inhibitors Fulltext Access 8 Pages 2006
Synthesis, analgesic, anti-inflammatory, ulcerogenic index and antibacterial activities of novel 2-methylthio-3-substituted-5,6,7,8-tetrahydrobenzo (b) thieno[2,3-d]pyrimidin-4(3H)-ones Fulltext Access 8 Pages 2006
Comparison of QSPR models of octanol/water partition coefficient for vitamins and non vitamins Fulltext Access 8 Pages 2006
Synthesis, characterisation, activities, cell uptake and DNA binding of a trinuclear complex: [{trans-PtCl(NH3)}2μ-{trans-Pd(NH3)(2-hydroxypyridine)-(H2N(CH2)6NH2)2]Cl4 Fulltext Access 8 Pages 2006
Synthesis, anticonvulsant activity and 5-HT1A, 5-HT2A receptor affinity of new N-[(4-arylpiperazin-1-yl)-alkyl] derivatives of 2-azaspiro[4.4]nonane and [4.5]decane-1,3-dione Fulltext Access 8 Pages 2006
Induction of apoptosis in A549 human lung cancer cells by all-trans retinoic acid incorporated in DOTAP/cholesterol liposomes Fulltext Access 8 Pages 2006
In vitro release of the mTOR inhibitor rapamycin from poly(ethylene glycol)-b-poly(ε-caprolactone) micelles Fulltext Access 8 Pages 2006
Alendronate-loaded nanoparticles deplete monocytes and attenuate restenosis Fulltext Access 8 Pages 2006
Using TEM to couple transient protein distribution and release for PLGA microparticles for potential use as vaccine delivery vehicles Fulltext Access 8 Pages 2006
Anti-angiogenic effects of liposomal prednisolone phosphate on B16 melanoma in mice Fulltext Access 8 Pages 2006
Stabilizing of plasmid DNA in vivo by PEG-modified cationic gold nanoparticles and the gene expression assisted with electrical pulses Fulltext Access 8 Pages 2006
Induction of cancer cell-specific apoptosis by folate-labeled cationic liposomes Fulltext Access 8 Pages 2006
Poly(trimethylene carbonate) and monomethoxy poly(ethylene glycol)-block-poly(trimethylene carbonate) nanoparticles for the controlled release of dexamethasone Fulltext Access 8 Pages 2006
Improved formulations of antisense oligodeoxynucleotides using wrapped liposomes Fulltext Access 8 Pages 2006
Enhanced anti-fibrotic activity of plasmid DNA expressing small interference RNA for TGF-β type II receptor for a mouse model of obstructive nephropathy by cationized gelatin prepared from different amine compounds Fulltext Access 8 Pages 2006
Novel oral insulin delivery systems based on complexation polymer hydrogels: Single and multiple administration studies in type 1 and 2 diabetic rats Fulltext Access 8 Pages 2006
Encapsulation of the immune potentiators MPL and RC529 in PLG microparticles enhances their potency Fulltext Access 8 Pages 2006
Design, synthesis and antiproliferative activity of some new azapyranoxanthenone aminoderivatives Fulltext Access 9 Pages 2006
Dynamic moisture sorption and desorption of standard and silicified microcrystalline cellulose Fulltext Access 9 Pages 2006
A new expert systems (SeDeM Diagram) for control batch powder formulation and preformulation drug products Fulltext Access 9 Pages 2006
Nitrofurylsemicarbazone Rhenium and Ruthenium Complexes as Anti-trypanosomal Agents Fulltext Access 9 Pages 2006
Synthesis and characterization of novel hydrazide–hydrazones and the study of their structure–antituberculosis activity Fulltext Access 9 Pages 2006
Synthesis, characterization, antimicrobial and single crystal X-ray crystallographic studies of some new sulfonyl, 4-chloro phenoxy benzene and dibenzoazepine substituted benzamides Fulltext Access 9 Pages 2006
Preparation and in vitro/in vivo evaluation of nano-sized crystals for dissolution rate enhancement of ucb-35440-3, a highly dosed poorly water-soluble weak base Fulltext Access 9 Pages 2006
Evaluation of cocktail approach to standardise Caco-2 permeability experiments Fulltext Access 9 Pages 2006
In vivo antitumor, in vitro antibacterial activity and alkylating properties of phosphorohydrazine derivatives of coumarin and chromone Fulltext Access 9 Pages 2006
Synthesis and biological properties of new α-methylene-γ-butyrolactones and α,β-unsaturated δ-lactones Fulltext Access 9 Pages 2006
Synthesis and evaluation of 7-amino-2-(2(3)-furyl)-5-phenylethylamino-oxazolo[5,4-d]pyrimidines as potential A2A adenosine receptor antagonists for positron emission tomography (PET) Fulltext Access 9 Pages 2006
Antibacterial and antifungal activity of acyclic and macrocyclic uracil derivatives with quaternized nitrogen atoms in spacers Fulltext Access 9 Pages 2006
Design and evaluation of “3 + 1” mixed ligand oxorhenium and oxotechnetium complexes bearing a nitroaromatic group with potential application in nuclear medicine oncology Fulltext Access 9 Pages 2006
Synthesis and in vitro activity of a series 1β-methylcarbapenem derivatives Fulltext Access 9 Pages 2006
Cryopreserved human hepatocytes in suspension are a convenient high throughput tool for the prediction of metabolic clearance Fulltext Access 9 Pages 2006
Cytotoxic 5-aryl-1-(4-nitrophenyl)-3-oxo-1,4-pentadienes mounted on alicyclic scaffolds Fulltext Access 9 Pages 2006
Molecular hurdles in polyfectin design and mechanistic background to polycation induced cytotoxicity Fulltext Access 9 Pages 2006
Synthesis and antiproliferative activity of benzo[d]isothiazole hydrazones Fulltext Access 9 Pages 2006
Application of two-photon microscopy to the study of cellular pharmacology of central neurons Fulltext Access 9 Pages 2006
In vitro mutagenicity of anti-inflammatory parsalmide analogues PA7, PA10, and PA31 triggered by biotransformation into hydroxy derivatives Fulltext Access 9 Pages 2006
Using cyclodextrin complexation to enhance secondary photoprotection of topically applied ibuprofen Fulltext Access 9 Pages 2006
Chitosan microparticles containing plasmid DNA as potential oral gene delivery system Fulltext Access 9 Pages 2006