Conversion of carbazole carboxamide based reversible inhibitors of Bruton's tyrosine kinase (BTK) into potent, selective irreversible inhibitors in the carbazole, tetrahydrocarbazole, and a new 2,3-dimethylindole series

Conversion of carbazole carboxamide based reversible inhibitors of Bruton's tyrosine kinase (BTK) into potent, selective irreversible inhibitors in the carbazole, tetrahydrocarbazole, and a new 2,3-dimethylindole series

Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Bioorganic & Medicinal Chemistry Letters - Volume 28, Issue 18, 1 October 2018, Pages 3080-3084

Qingjie Liu, Douglas G. Batt, Charu Chaudhry, Jonathan S. Lippy, Mark A. Pattoli, Neha Surti, Songmei Xu, Percy H. Carter, James R. Burke, Joseph A. Tino,