Cryptadines A and B, novel C27N3-type pentacyclic alkaloids from Lycopodium cryptomerinum Fulltext Access 6 Pages 2007
(1R,2S)-4-(2-Cyano-cyclohexyl-oxy)-2-trifluoromethyl-benzonitrile, a potent androgen receptor antagonist for stimulating hair growth and reducing sebum production Fulltext Access 6 Pages 2007
Design, synthesis, and biological evaluation of triazolopiperazine-based β-amino amides as potent, orally active dipeptidyl peptidase IV (DPP-4) inhibitors Fulltext Access 6 Pages 2007
Discovery, synthesis, and structure–activity studies of tetrazole based growth hormone secretagogues Fulltext Access 6 Pages 2007
Structure–activity relationship (SAR) investigations of substituted imidazole analogs as TRPV1 antagonists Fulltext Access 6 Pages 2007
Synthesis and TNF expression inhibitory properties of new thalidomide analogues derived via Heck cross coupling Fulltext Access 6 Pages 2007
4-Arylcyclohexylalanine analogs as potent, selective, and orally active inhibitors of dipeptidyl peptidase IV Fulltext Access 6 Pages 2007
Pentacyclic triterpenes. Part 5: Synthesis and SAR study of corosolic acid derivatives as inhibitors of glycogen phosphorylases Fulltext Access 6 Pages 2007
Natural triterpenoids from Cecropia lyratiloba are cytotoxic to both sensitive and multidrug resistant leukemia cell lines Fulltext Access 6 Pages 2007
Role of glutamate 243 in the active site of 2-deoxy-scyllo-inosose synthase from Bacillus circulans Fulltext Access 6 Pages 2007
Preparation and antitubercular activities of alkylated amino alcohols and their glycosylated derivatives Fulltext Access 6 Pages 2007
Synthesis and evaluation of N-acylsulfonamide and N-acylsulfonylurea prodrugs of a prostacyclin receptor agonist Fulltext Access 6 Pages 2007
Highly efficient antitumor agents of heterocycles containing sulfur atom: Linear and angular thiazonaphthalimides against human lung cancer cell in vitro Fulltext Access 6 Pages 2007
Novel (E)-2-(aryl)-3-(4-methanesulfonylphenyl)acrylic ester prodrugs possessing a diazen-1-ium-1,2-diolate moiety: Design, synthesis, cyclooxygenase inhibition, and nitric oxide release studies Fulltext Access 6 Pages 2007
Carbonic anhydrase inhibitors: The inhibition profiles of the human mitochondrial isoforms VA and VB with anions are very different Fulltext Access 6 Pages 2007
Bivalent ligand approach on 4-[2-(3-methoxyphenyl)ethyl]-1-(2-methoxyphenyl)piperazine: Synthesis and binding affinities for 5-HT7 and 5-HT1A receptors Fulltext Access 6 Pages 2007
New amino and acetamido monomethine cyanine dyes for the detection of DNA in agarose gels Fulltext Access 6 Pages 2007
3-Hydroxy-1,5-dihydro-pyrrol-2-one derivatives as advanced inhibitors of HIV integrase Fulltext Access 6 Pages 2007
Molecular design of anti-MRSA agents based on the anacardic acid scaffold Fulltext Access 6 Pages 2007
Fatty acyl amides of endogenous tetrahydroisoquinolines are active at the recombinant human TRPV1 receptor Fulltext Access 6 Pages 2007
Malondialdehyde scavenging and aldose-derived Schiff bases’ transglycation properties of synthetic histidyl-hydrazide carnosine analogs Fulltext Access 6 Pages 2007
Synthesis and anti-inflammatory activity of 3-(4′-geranyloxy-3′-methoxyphenyl)-2-trans propenoic acid and its ester derivatives Fulltext Access 6 Pages 2007
A novel series of potent cytotoxic agents targeting G2/M phase of the cell cycle and demonstrating cell killing by apoptosis in human breast cancer cells Fulltext Access 6 Pages 2007
Agonist lead identification for the high affinity niacin receptor GPR109a Fulltext Access 6 Pages 2007
Design, synthesis, and evaluation of isoindolinone-hydroxamic acid derivatives as histone deacetylase (HDAC) inhibitors Fulltext Access 6 Pages 2007
Synthesis of desformylflustrabromine and its evaluation as an α4β2 and α7 nACh receptor modulator Fulltext Access 6 Pages 2007
Synthesis of novel bicyclo[4.1.0]heptane and bicyclo[3.1.0]hexane derivatives as melanin-concentrating hormone receptor R1 antagonists Fulltext Access 6 Pages 2007
Synthesis and antibacterial activity of novel oxazolidinones with methylene oxygen- and methylene sulfur-linked substituents at C5-position Fulltext Access 6 Pages 2007
Identification and characterization of 3-substituted pyrazolyl esters as alternate substrates for cathepsin B: The confounding effects of DTT and cysteine in biological assays Fulltext Access 6 Pages 2007
Synthesis, structure analysis, and antibacterial activity of some novel 10-substituted 2-(4-piperidyl/phenyl)-5,5-dioxo[1,2,4]triazolo[1,5-b][1,2,4]benzothiadiazine derivatives Fulltext Access 6 Pages 2007
Kinesin spindle protein (KSP) inhibitors. Part 6: Design and synthesis of 3,5-diaryl-4,5-dihydropyrazole amides as potent inhibitors of the mitotic kinesin KSP Fulltext Access 6 Pages 2007
Design and synthesis of quinolin-2(1H)-one derivatives as potent CDK5 inhibitors Fulltext Access 6 Pages 2007
Small conformationally restricted piperidine N-arylsulfonamides as orally active γ-secretase inhibitors Fulltext Access 6 Pages 2007
Cytotoxicity of the novel spin trapping compound 5-ethoxycarbonyl-3,5-dimethyl-pyrroline N-oxide (3,5-EDPO) and its derivatives Fulltext Access 6 Pages 2007
Kinesin spindle protein (KSP) inhibitors. Part 8: Design and synthesis of 1,4-diaryl-4,5-dihydropyrazoles as potent inhibitors of the mitotic kinesin KSP Fulltext Access 6 Pages 2007
Kinesin spindle protein (KSP) inhibitors. Part 7: Design and synthesis of 3,3-disubstituted dihydropyrazolobenzoxazines as potent inhibitors of the mitotic kinesin KSP Fulltext Access 6 Pages 2007
Cyanopyridyl containing 1,4-dihydroindeno[1,2-c]pyrazoles as potent checkpoint kinase 1 inhibitors: Improving oral biovailability Fulltext Access 6 Pages 2007
Design, synthesis, and cytostatic activity of novel cyclic curcumin analogues Fulltext Access 6 Pages 2007
Discovery of potent HIV-1 protease inhibitors incorporating sulfoximine functionality Fulltext Access 6 Pages 2007
Pyrazole inhibitors of HMG-CoA reductase: An attempt to dramatically reduce synthetic complexity through minimal analog re-design Fulltext Access 6 Pages 2007
Structure–activity relationship study of novel NR2B-selective antagonists with arylamides to avoid reactive metabolites formation Fulltext Access 6 Pages 2007
From ATP to AZD6140: The discovery of an orally active reversible P2Y12 receptor antagonist for the prevention of thrombosis Fulltext Access 6 Pages 2007
High-throughput determination of OROS® drug release rate profile using micro parallel liquid chromatography Fulltext Access 6 Pages 2007
Determination of loratadine and its active metabolite in human plasma by high-performance liquid chromatography with mass spectrometry detection Fulltext Access 6 Pages 2007
Application of an improved column characterisation system to evaluate the within and between batch variability Fulltext Access 6 Pages 2007
Validation and application of a stability-indicating HPLC method for the in vitro determination of gastric and intestinal stability of venlafaxine Fulltext Access 6 Pages 2007
A novel quantification method of pantaprazole sodium monohydrate in sesquihydrate by thermogravimetric analyzer Fulltext Access 6 Pages 2007
Development and validation of a method for quantitative determination of valsartan in human plasma by liquid chromatography-tandem mass spectrometry Fulltext Access 6 Pages 2007
Determination of fentanyl in human plasma by head-space solid-phase microextraction and gas chromatography–mass spectrometry Fulltext Access 6 Pages 2007
Simultaneous determination of nikethamide and lidocaine in human blood and cerebrospinal fluid by high performance liquid chromatography Fulltext Access 6 Pages 2007
Simultaneous quantification of five major bioactive flavonoids in Rhizoma Smilacis Glabrae by high-performance liquid chromatography Fulltext Access 6 Pages 2007
Separation and determination of four active components in medicinal preparations by flow injection-capillary electrophoresis Fulltext Access 6 Pages 2007
An approach to develop binary chromatographic fingerprints of the total alkaloids from Caulophyllum robustum by high performance liquid chromatography/diode array detector and gas chromatography/mass spectrometry Fulltext Access 6 Pages 2007
Simultaneous determination of nitrendipine and one of its metabolites in plasma samples by gas chromatography with electron-capture detection Fulltext Access 6 Pages 2007
Carbon film resistor electrode for amperometric determination of acetaminophen in pharmaceutical formulations Fulltext Access 6 Pages 2007
Extraction spectrophotometric determination of aluminum in dialysis concentrates with 3,5-ditertbutylsalicylfluorone and ionic liquid 1-butyl-3-trimethylsilylimidazolium hexafluorophosphate Fulltext Access 6 Pages 2007
Development and validation of a rapid HPLC method for the determination of oseltamivir phosphate in Tamiflu® and generic versions Fulltext Access 6 Pages 2007
Validation of rapid and simple LC–MS/MS method for determination of voriconazole in rat plasma Fulltext Access 6 Pages 2007
Separation and determination of flavonoids in Lamiophlomis rotata by capillary electrophoresis using borate as electrolyte Fulltext Access 6 Pages 2007
Quantitative determination of 1-deoxynojirimycin in mulberry leaves using liquid chromatography–tandem mass spectrometry Fulltext Access 6 Pages 2007
Development and validation of a high performance liquid chromatographic method for the determination of oxcarbazepine and its main metabolites in human plasma and cerebrospinal fluid and its application to pharmacokinetic study Fulltext Access 6 Pages 2007
Assay of artemether, methylparaben and propylparaben in a formulated paediatric antimalarial dry suspension Fulltext Access 6 Pages 2007
Development and validation of a LC-MS/MS method with electrospray ionization for determination of LASSBio-579 in rat plasma Fulltext Access 6 Pages 2007
A direct HPLC method to estimate streptomycin and its putative ototoxic derivative, streptidine, in blood serum: Application to streptomycin-treated humans Fulltext Access 6 Pages 2007
Rapid quantification of malondialdehyde in plasma by high performance liquid chromatography–visible detection Fulltext Access 6 Pages 2007
Development and validation of reversed phase high performance liquid chromatography method for determination of dexpanthenol in pharmaceutical formulations Fulltext Access 6 Pages 2007
Synthesis and antimicrobial activity of some new thiazolyl thiazolidine-2,4-dione derivatives Fulltext Access 6 Pages 2007
Comparative rates of sialylation by recombinant trans-sialidase and inhibitor properties of synthetic oligosaccharides from Trypanosoma cruzi mucins-containing galactofuranose and galactopyranose Fulltext Access 6 Pages 2007
Antidiabetic copper(II)-picolinate: Impact of the first transition metal in the metallopicolinate complexes Fulltext Access 6 Pages 2007
Mechanism of the melanogenesis stimulation activity of (−)-cubebin in murine B16 melanoma cells Fulltext Access 6 Pages 2007
Sulfated glucosamine inhibits MMP-2 and MMP-9 expressions in human fibrosarcoma cells Fulltext Access 6 Pages 2007
Conformation selectivity in the binding of diazepam and analogues to α1-acid glycoprotein Fulltext Access 6 Pages 2007
Mass transport kinetics of the DNA-binding dye Hoechst-33342 into bovine spermatozoa Fulltext Access 6 Pages 2007
Determination of bismuth in pharmaceutical products using methyltriphenylphosphonium bromide as a molecular probe by resonance light scattering technique Fulltext Access 6 Pages 2007
Simultaneous determination of neomycin sulfate and polymyxin B sulfate by capillary electrophoresis with indirect UV detection Fulltext Access 6 Pages 2007
Simultaneous analysis of eight bioactive compounds in Danning tablet by HPLC-ESI-MS and HPLC-UV Fulltext Access 6 Pages 2007
Simultaneous determination of eight components in Radix Tinosporae by high-performance liquid chromatography coupled with diode array detector and electrospray tandem mass spectrometry Fulltext Access 6 Pages 2007
Simultaneous determination of sildenafil and N-desmethyl sildenafil in human plasma by high-performance liquid chromatography method using electrochemical detection with application to a pharmacokinetic study Fulltext Access 6 Pages 2007
High-performance liquid chromatography–electrospray ionization mass spectrometry determination of sodium ferulate in human plasma Fulltext Access 6 Pages 2007
Analysis of dencichine in Panax notoginseng by gas chromatography–mass spectrometry with ethyl chloroformate derivatization Fulltext Access 6 Pages 2007
Method development and validation for the simultaneous determination of cetirizine dihydrochloride, paracetamol, and phenylpropanolamine hydrochloride in tablets by capillary zone electrophoresis Fulltext Access 6 Pages 2007
A rapid HPLC method for simultaneous determination of tretinoin and isotretinoin in dermatological formulations Fulltext Access 6 Pages 2007
Analysis of plasmid DNA damage induced by melanin with capillary electrophoresis Fulltext Access 6 Pages 2007
Fingerprint analysis of fruiting bodies of cultured Cordyceps militaris by high-performance liquid chromatography–photodiode array detection Fulltext Access 6 Pages 2007
Quality assessment of Rhizoma et Radix Notopterygii by HPTLC and HPLC fingerprinting and HPLC quantitative analysis Fulltext Access 6 Pages 2007
Study on the interaction between salicylic acid and catalase by spectroscopic methods Fulltext Access 6 Pages 2007
Structural elucidation of in vivo and in vitro metabolites of anisodine by liquid chromatography–tandem mass spectrometry Fulltext Access 6 Pages 2007
Simultaneous determination of six major stilbenes and flavonoids in Smilax china by high performance liquid chromatography Fulltext Access 6 Pages 2007