Asymmetric synthesis of novel tetrahydroquinoline derivatives with a sugar building block and their bioactivities Fulltext Access 4 Pages 2005
Synthesis and in vitro biological evaluation of a carbon glycoside analogue of morphine-6-glucuronide Fulltext Access 4 Pages 2005
Synthesis of isonicotinic acid Nâ²-arylidene-N-[2-oxo-2-(4-aryl-piperazin-1-yl)-ethyl]-hydrazides as antituberculosis agents Fulltext Access 4 Pages 2005
Novel cyclized Pifithrin-α p53 inactivators: synthesis and biological studies Fulltext Access 4 Pages 2005
3H-Quinazolin-4-ones as a new calcilytic template for the potential treatment of osteoporosis Fulltext Access 4 Pages 2005
Identification of small molecule inhibitors of the hepatitis C virus RNA-dependent RNA polymerase from a pyrrolidine combinatorial mixture Fulltext Access 4 Pages 2005
Antitubercular agents. Part 1: Synthesis of phthalimido- and naphthalimido-linked phenazines as new prototype antitubercular agents Fulltext Access 4 Pages 2005
Molecular-modeling based design, synthesis, and activity of substituted piperidines as γ-secretase inhibitors Fulltext Access 4 Pages 2005
Synthesis and pharmacological investigation of novel 1-substituted-4-phenyl-1,2,4-triazolo[4,3-a]quinazolin-5(4H)-ones as a new class of H1-antihistaminic agents Fulltext Access 4 Pages 2005
Structure-activity relationship of the novel bivalent and C-terminal modified analogues of endomorphin-2 Fulltext Access 4 Pages 2005
Structure-activity relationship studies on tetralin carboxamide growth hormone secretagogue receptor antagonists Fulltext Access 4 Pages 2005
Aminocyanopyridine inhibitors of mitogen activated protein kinase-activated protein kinase 2 (MK-2) Fulltext Access 4 Pages 2005
Enhancement in antimicrobial activity of 2-(phenyl)-3-(2-butyl-4-chloro-1H-imidazolyl)-5-butylate isoxazolidine Fulltext Access 4 Pages 2005
Potent pyrimidinetrione-based inhibitors of MMP-13 with enhanced selectivity over MMP-14 Fulltext Access 4 Pages 2005
Novel fluoroquinolones: design, synthesis, and in vivo activity in mice against Mycobacterium tuberculosis H37Rv Fulltext Access 4 Pages 2005
Structure-activity relationships of the oxindole growth hormone secretagogues Fulltext Access 4 Pages 2005
Novel 2-aminothiazonaphthalimides as visible light activatable photonucleases: effects of intercalation, heterocyclic-fused area and side chains Fulltext Access 4 Pages 2005
N-Acyl arylsulfonamides as novel, reversible inhibitors of human steroid sulfatase Fulltext Access 4 Pages 2005
Discovery and structure-activity relationships of 2-benzylpyrrolidine-substituted aryloxypropanols as calcium-sensing receptor antagonists Fulltext Access 4 Pages 2005
Halogenated and isosteric cytisine derivatives with increased affinity and functional activity at nicotinic acetylcholine receptors Fulltext Access 4 Pages 2005
The structure of the capsular polysaccharide of Shewanella oneidensis strain MR-4 Fulltext Access 4 Pages 2005
Determination of the degree of deacetylation of chitin and chitosan by X-ray powder diffraction Fulltext Access 4 Pages 2005
Preparation of dehydro-l-ascorbic acid dimer by air oxidation of l-ascorbic acid in the presence of catalytic amounts of copper(II) acetate and pyridine Fulltext Access 4 Pages 2005
Further evidence of the changing nature of biopolymer networks in the presence of sugar Fulltext Access 4 Pages 2005
Synthesis of 2,3-unsaturated C-glycosides by HClO4-SiO2 catalyzed Ferrier rearrangement of glycals Fulltext Access 4 Pages 2005
Preparation of N-nosyl-3,4-epimines derived from levoglucosan by sodium borohydride reduction Fulltext Access 4 Pages 2005
Structure of 2-C-(hydroxymethyl)-d-ribose (hamamelose) in the solid-state analyzed by CP MAS NMR and X-ray crystallography Fulltext Access 4 Pages 2005
The crystal structure of a cyclic glycolipid reveals a carbohydrate-carbohydrate interaction interface Fulltext Access 4 Pages 2005
One-pot synthesis of per-O-acetylated thioglycosides from unprotected reducing sugars Fulltext Access 4 Pages 2005
Carbonic anhydrase inhibitors. Interaction of isozymes I, II, IV, V, and IX with organic phosphates and phosphonates Fulltext Access 4 Pages 2005
Nonpeptide αvβ3 antagonists: identification of potent, chain-shortened 7-oxo RGD mimetics Fulltext Access 4 Pages 2005
3-(2,5-Dihydro-1H-pyrrol-2-ylmethoxy)pyridines: synthesis and analgesic activity Fulltext Access 4 Pages 2005
3-Arylidene-1-(4-nitrophenylmethylene)-3,4-dihydro-1H-naphthalen-2-ones and related compounds displaying selective toxicity and reversal of multidrug resistance in neoplastic cells Fulltext Access 4 Pages 2005
Synthesis and activity of oleanolic acid derivatives, a novel class of inhibitors of osteoclast formation Fulltext Access 4 Pages 2005
The stability of lipidic analogues of GnRH in plasma and kidney preparations: the stereoselective release of the parent peptide Fulltext Access 4 Pages 2005
Inositol tripyrophosphate: a new membrane permeant allosteric effector of haemoglobin Fulltext Access 4 Pages 2005
Cyclization-activated prodrugs. Synthesis, reactivity and toxicity of dipeptide esters of paracetamol Fulltext Access 4 Pages 2005
Pyrazolo[1,5-a]pyrimidin-7-yl phenyl amides as novel anti-proliferative agents: parallel synthesis for lead optimization of amide region Fulltext Access 4 Pages 2005
Ability of thrombin to act as molecular chaperone, inducing formation of quadruplex structure of thrombin-binding aptamer Fulltext Access 4 Pages 2005
Synthesis and biological activity of the tea catechin metabolites, M4 and M6 and their methoxy-derivatives Fulltext Access 4 Pages 2005
Determination of coenzyme Q biosynthesis in cultured cells without the necessity for lipid extraction Fulltext Access 4 Pages 2005
Carbohydrate analysis by a phenol-sulfuric acid method in microplate format Fulltext Access 4 Pages 2005
Effect of sampling interval on the use of “doubly labeled” water for measuring CO2 production Fulltext Access 4 Pages 2005
Gradient polymerase chain reaction performance using regular thermal cycle machine Fulltext Access 4 Pages 2005
Gold layer-based dual crosslinking procedure of glucose oxidase with ferrocene monocarboxylic acid provides a stable biosensor Fulltext Access 4 Pages 2005
Reversed-phase HPLC with UV detection for the determination of N-acetylaspartate and creatine Fulltext Access 4 Pages 2005
High-density fluorescently labeled rolling-circle amplicons for DNA diagnostics Fulltext Access 4 Pages 2005
Capturing SDS-treated biotinylated protein and peptide by avidin functional affinity electrophoresis with or without SDS in the gel running buffer Fulltext Access 4 Pages 2005
A method for functional mouse MDR3 P-glycoprotein reconstitution in Escherichia coli lipids Fulltext Access 4 Pages 2005
Chemoenzymatic synthesis of CD52 glycoproteins carrying native N-glycans Fulltext Access 4 Pages 2005
Fluorescent assay for studying the substrate specificity of neuraminidase Fulltext Access 4 Pages 2005
SVM-BALSA: Remote homology detection based on Bayesian sequence alignment Fulltext Access 4 Pages 2005
A common sequence-associated physicochemical feature for proteins of beta-trefoil family Fulltext Access 4 Pages 2005
Survival analysis of microarray expression data by transformation models Fulltext Access 4 Pages 2005
A molecular docking model of SARS-CoV S1 protein in complex with its receptor, human ACE2 Fulltext Access 4 Pages 2005
Mild conditions for releasing mono and bis-biotinylated macromolecules from immobilized streptavidin Fulltext Access 4 Pages 2005
Usefulness of repeated GenomiPhi, a phi29 DNA polymerase-based rolling circle amplification kit, for generation of large amounts of plasmid DNA Fulltext Access 4 Pages 2005
Selection and characteristics of peptides that bind thermally grown silicon dioxide films Fulltext Access 4 Pages 2005
7α,11β-Dimethyl-19-nortestosterone: a potent and selective androgen response modulator with prostate-sparing properties Fulltext Access 4 Pages 2005
Synthesis and structure-activity relationships of isoxazole carboxamides as growth hormone secretagogue receptor antagonists Fulltext Access 4 Pages 2005
Dipyridyl amides: potent metabotropic glutamate subtype 5 (mGlu5) receptor antagonists Fulltext Access 4 Pages 2005
Effects of a verbenachalcone derivative on neurite outgrowth, inhibition of caspase induction and gene expression Fulltext Access 4 Pages 2005
Pyrrolidinedione derivatives as antibacterial agents with a novel mode of action Fulltext Access 4 Pages 2005
Uric acid may inhibit glucose-induced insulin secretion via binding to an essential arginine residue in rat pancreatic β-cells Fulltext Access 4 Pages 2005
Design, synthesis and antiinflammatory activity of novel phthalimide derivatives, structurally related to thalidomide Fulltext Access 4 Pages 2005
De novo design, synthesis, and in vitro activity of LFA-1 antagonists based on a bicyclic[5.5]hydantoin scaffold Fulltext Access 4 Pages 2005
Five-member thio-heterocyclic fused naphthalimides with aminoalkyl side chains: intercalation and photocleavage to DNA Fulltext Access 4 Pages 2005
Synthesis of half-mustard combi-molecules with fluorescence properties: correlation with EGFR status Fulltext Access 4 Pages 2005
Reversal of anticancer drug resistance by COTC based on intracellular glutathione and glyoxalase I Fulltext Access 4 Pages 2005
Salt-assisted acid hydrolysis of chitosan to oligomers under microwave irradiation Fulltext Access 4 Pages 2005
Structure-activity relations of azafluorenone and azaanthraquinone as antimicrobial compounds Fulltext Access 4 Pages 2005
Design, synthesis, and evaluation of oxazole transthyretin amyloidogenesis inhibitors Fulltext Access 4 Pages 2005
Detection and control of aspartimide formation in the synthesis of cyclic peptides Fulltext Access 4 Pages 2005
Tryptamine-based human β3-adrenergic receptor agonists. Part 3: Improved oral bioavailability via modification of the sulfonamide moiety Fulltext Access 4 Pages 2005
Antimitotic activity and reversal of breast cancer resistance protein-mediated drug resistance by stilbenoids from Bletilla striata Fulltext Access 4 Pages 2005
Synthesis and pharmacological evaluation of substituted 5-[4-[2-(6,7-dimethyl-1,2,3,4-tetrahydro-2-oxo-4-quinoxalinyl)ethoxy]phenyl]methylene]thiazolidine-2,4-dione derivatives as potent euglycemic and hypolipidemic agents Fulltext Access 4 Pages 2005
Synthesis of ring-substituted 4-aminoquinolines and evaluation of their antimalarial activities Fulltext Access 4 Pages 2005
Synthesis of argentatin A derivatives as growth inhibitors of human cancer cell lines in vitro Fulltext Access 4 Pages 2005
Two new irreversible inhibitors of dihydrodipicolinate synthase: diethyl (E,E)-4-oxo-2,5-heptadienedioate and diethyl (E)-4-oxo-2-heptenedioate Fulltext Access 4 Pages 2005
Studies towards the next generation of antidepressants. Part 4: Derivatives of 4-(5-fluoro-1H-indol-3-yl)cyclohexylamine with affinity for the serotonin transporter and the 5-HT1A receptor Fulltext Access 4 Pages 2005