Bioremediation of uranium-contaminated groundwater: a systems approach to subsurface biogeochemistry

► Microbial reduction of U(VI) can remove uranium from contaminated groundwater. ► Concerns about the stability of precipitated uranium need further study. ► Environmental omics is useful for diagnosing in situ physiological state of microbes. ► Genome-scale modeling of in situ activity of bioremediation organisms is possible.