Bio-silica and bio-polyphosphate: applications in biomedicine (bone formation)

► Siliceous skeletal elements from sponges as blueprints for the biofabrication of inorganic-organic composites and biomaterials. ► Preparation of bio-silica and bio-polyphosphate as morphogenetic material for nano-biomedical applications. ► Increase in the OPG and RANKL gene expression ratio. ► Potential application in the treatment of osteoporosis.