کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10232436 42519 2005 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Adding value to fusion proteins through covalent labelling
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی بیو مهندسی (مهندسی زیستی)
پیش نمایش صفحه اول مقاله
Adding value to fusion proteins through covalent labelling
چکیده انگلیسی
Recombinant proteins are often expressed with an additional polypeptide the role of which is to aid purification, detection or functional studies. Recently, the role of these tags has been extended to mediate the labelling of the protein of interest with chemically diverse compounds. These approaches are of importance for protein science as they allow proteins to be equipped with properties that cannot be genetically encoded and also enable the use of a single fusion protein for several different applications. Several new approaches have been developed for the covalent labelling of fusion proteins both in living cells and in vitro.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Biotechnology - Volume 16, Issue 4, August 2005, Pages 453-458
نویسندگان
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