کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10337209 | 692753 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Accurate prediction of scorpion toxin functional properties from primary structures
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
شیمی
شیمی تئوریک و عملی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Accurate prediction of scorpion toxin functional properties from primary structures Accurate prediction of scorpion toxin functional properties from primary structures](/preview/png/10337209.png)
چکیده انگلیسی
Scorpion toxins are common experimental tools for studies of biochemical and pharmacological properties of ion channels. The number of functionally annotated scorpion toxins is steadily growing, but the number of identified toxin sequences is increasing at much faster pace. With an estimated 100,000 different variants, bioinformatic analysis of scorpion toxins is becoming a necessary tool for their systematic functional analysis. Here, we report a bioinformatics-driven system involving scorpion toxin structural classification, functional annotation, database technology, sequence comparison, nearest neighbour analysis, and decision rules which produces highly accurate predictions of scorpion toxin functional properties.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Molecular Graphics and Modelling - Volume 24, Issue 1, September 2005, Pages 17-24
Journal: Journal of Molecular Graphics and Modelling - Volume 24, Issue 1, September 2005, Pages 17-24
نویسندگان
Paul T.J. Tan, K.N. Srinivasan, Seng Hong Seah, Judice L.Y. Koh, Tin Wee Tan, Shoba Ranganathan, Vladimir Brusic,