کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10344584 | 697864 | 2012 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
On the prediction of glucose concentration under intra-patient variability in type 1 diabetes: A monotone systems approach
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
علوم کامپیوتر (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
A monotonicity analysis of the model states and parameters is performed. An analysis of critical points, state transformations and application of differential inequalities are proposed to deal with non-monotone parameters. In contrast to current methods, the guaranteed simulations for the glucose-insulin model are carried out by considering uncertainty in all the parameters and initial conditions. Furthermore, no time-discretisation is required, which helps to reduce the computational time significantly. As a result, we are able to compute a tight glucose envelope that bounds all the possible patient's glycemic responses with low computational effort.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computer Methods and Programs in Biomedicine - Volume 108, Issue 3, December 2012, Pages 993-1001
Journal: Computer Methods and Programs in Biomedicine - Volume 108, Issue 3, December 2012, Pages 993-1001
نویسندگان
Diego de Pereda, Sergio Romero-Vivo, Beatriz Ricarte, Jorge Bondia,