کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
10345572 698342 2013 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
pocrm: An R-package for Phase I trials of combinations of agents
موضوعات مرتبط
مهندسی و علوم پایه مهندسی کامپیوتر علوم کامپیوتر (عمومی)
پیش نمایش صفحه اول مقاله
pocrm: An R-package for Phase I trials of combinations of agents
چکیده انگلیسی
This paper presents the R package pocrm for implementing and simulating the partial order continual reassessment method (PO-CRM; [1], [2]) in Phase I trials of combinations of agents. The aim of this article is to illustrate, through examples of the pocrm package, how the PO-CRM works and how its operating characteristics can inform clinical trial investigators. This should promote the use of the PO-CRM in designing and conducting dose-finding Phase I trials of combinations of agents.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computer Methods and Programs in Biomedicine - Volume 112, Issue 1, October 2013, Pages 211-218
نویسندگان
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