کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10351237 | 864341 | 2005 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Digital staining for multispectral images of pathological tissue specimens based on combined classification of spectral transmittance
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موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
نرم افزارهای علوم کامپیوتر
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Digital staining for multispectral images of pathological tissue specimens based on combined classification of spectral transmittance Digital staining for multispectral images of pathological tissue specimens based on combined classification of spectral transmittance](/preview/png/10351237.png)
چکیده انگلیسی
In this study, the digital transformation (digital staining) of the 16-band multispectral image of a hematoxylin and eosin (HE) stained pathological specimen to its Masson's trichrome (MT) stained counterpart is addressed. The digital staining procedure involves the classification of the various H&E-stained tissue components and then the transformation of their transmittance spectra to their equivalent MT-stained transmittance configurations. Combination of transmittance classifiers were designed to classify the various tissue components found in the multispectral images of an HE-stained specimen, e.g. nucleus, cytoplasm, red blood cell (RBC), fibrosis, etc.; while pseudo-inverse method was used to obtain the transformation matrices that would translate the transmittance spectra of the classified HE-stained multispectral pixels to their MT-stained configurations. To generate the digitally stained image, weighting factors, which were based on the classifiers beliefs, were introduced to the generated transformation matrices. Initial results of our experiments on liver specimens show the viability of multispectral imaging (MSI) to implement a digital staining framework in the pathological context.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computerized Medical Imaging and Graphics - Volume 29, Issue 8, December 2005, Pages 649-657
Journal: Computerized Medical Imaging and Graphics - Volume 29, Issue 8, December 2005, Pages 649-657
نویسندگان
Pinky A. Bautista, Tokiya Abe, Masahiro Yamaguchi, Yukako Yagi, Nagaaki Ohyama,