کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
10351561 | 864493 | 2012 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A novel algorithm combining support vector machine with the discrete wavelet transform for the prediction of protein subcellular localization
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
مهندسی کامپیوتر
نرم افزارهای علوم کامپیوتر
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A novel algorithm combining support vector machine with the discrete wavelet transform for the prediction of protein subcellular localization A novel algorithm combining support vector machine with the discrete wavelet transform for the prediction of protein subcellular localization](/preview/png/10351561.png)
چکیده انگلیسی
Knowing the subcellular localization of proteins within the cell is an important step in elucidating its role in biological processes, its function and its potential as a drug target for disease diagnosis. As the number of complete genomes rapidly increases, accurate and efficient methods that automatically predict the subcellular localizations become more urgent. In the current paper, we developed a novel method that coupled the discrete wavelet transform with support vector machine based on the amino acid polarity to predict the subcellular localizations of prokaryotic and eukaryotic proteins. The results obtained by the jackknife test were quite promising, and indicated that the proposed method remarkably improved the prediction accuracy of subcellular locations, and could be as an effective and promising high-throughput method in the subcellular localization research.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Computers in Biology and Medicine - Volume 42, Issue 2, February 2012, Pages 180-187
Journal: Computers in Biology and Medicine - Volume 42, Issue 2, February 2012, Pages 180-187
نویسندگان
Ru-Ping Liang, Shu-Yun Huang, Shao-Ping Shi, Xing-Yu Sun, Sheng-Bao Suo, Jian-Ding Qiu,