Impedimetric biosensor based on self-assembled hybrid cystein-gold nanoparticles and CramoLL lectin for bacterial lipopolysaccharide recognition

► A new strategy to construct an electrochemical biosensor for bacterial LPS has been described. ► AFM images showed that LPS was specifically recognized. ► A sensor for selective discrimination of LPS types with high sensitivity has been achieved. ► The biosensor provides an appropriate biomimetic interface for specific recognition of LPS.