Streaming current and wall dissolution over 48Â h in silica nanochannels

► Fabrication and modeling of bare and cyanosilane-coated fused silica nanochannels. ► 2D modeling coupling chemical equilibrium theory for surface and bulk. ► Continuous measurements of streaming currents in silica nanochannels over 48 h. ► Developed method for determination of dissolution rates of silica under confinement.